Abstract:
BACKGROUND:Disparities in treatment and mortality for colorectal cancer (CRC) may reflect differences in access to specialized care or other characteristics of the area where an individual lives. METHODS:Surveillance, Epidemiology and End Results Program-Medicare data for seniors diagnosed with CRC were linked to area measures of the sociodemographic characteristics and the capacity of surgeons, medical oncologists, and radiation oncologists. Outcomes included receipt of stage-appropriate CRC care and mortality. RESULTS:After adjustment, blacks and Hispanics were less likely than whites to undergo surgery (odds ratio [OR] 0.57, 95% confidence interval (CI) 0.52-0.63 and OR 0.82, 95% CI 0.70-0.95, respectively). Individuals who lived in areas with the highest tertile of surgeon capacity were more likely to undergo resection than those in the lowest, and use of surgery declined as the percentage of blacks in the area increased. Adjustment for the area measures resulted in a modest decline in disparities in care relative to whites (5.3% for black). Blacks also experienced greater all-cause and cancer-specific mortality than whites. Further adjustment for area sociodemographics and surgeon capacity reduced the disparity in mortality between blacks and whites. Although there was a similar black/white disparity in the use of adjuvant chemotherapy, the disparity remained after adjustment for area characteristics, although use of chemotherapy was greater in areas with the greatest capacity of medical oncologists. CONCLUSIONS:Sociodemographic characteristics and measures of the availability of specialized cancer providers in the area in which an individual resides modestly mediated disparities in the receipt of CRC care and mortality, suggesting that other factors may also be important.
journal_name
Cancerjournal_title
Cancerauthors
Haas JS,Brawarsky P,Iyer A,Fitzmaurice GM,Neville BA,Earle Cdoi
10.1002/cncr.26034subject
Has Abstractpub_date
2011-09-15 00:00:00pages
4267-76issue
18eissn
0008-543Xissn
1097-0142journal_volume
117pub_type
杂志文章相关文献
CANCER文献大全abstract::To assess the efficacy and safety of Adriamycin (Adria Laboratories, Columbus, OH) in inoperable hepatocellular carcinoma (HCC), 60 patients were randomized to receive Adriamycin 60 to 75 mg/m2 at 3-week intervals and 46 patients to receive no antitumor therapy. The median survival rate of the Adriamycin group was 10....
journal_title:Cancer
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/1097-0142(19880801)62:3<479::aid-cncr28206
更新日期:1988-08-01 00:00:00
abstract::The 136 patients who underwent total laryngectomy as the primary treatment for squamous cell carcinoma of the glottis at the Mayo Clinic in 1970 through 1981 were followed by retrospective record review for at least 4 years or until death, local recurrence, neck recurrence, or delayed neck metastasis. Cancer recurred ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19890701)64:1<143::aid-cncr28206
更新日期:1989-07-01 00:00:00
abstract::Testis cancer and ichthyosis are both relatively rare diseases. Hence the finding of six individuals with both these conditions in a small population with testicular cancer is highly conspicuous and indicates some kind of connection among such persons. Despite the identical clinical appearances of their ichthyoses, th...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19910201)67:3<730::aid-cncr28206
更新日期:1991-02-01 00:00:00
abstract::To test the hypothesis that there is a positive association between chronic alcoholism and carcinoma of the pancreas, the mortality experience of 1382 chronic alcoholics was studied. Analysis was limited to a comparison of observed and expected proportional mortality of different causes of death in the 894 whites who ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197509)36:3<1077::aid-cncr282036
更新日期:1975-09-01 00:00:00
abstract:BACKGROUND:Malignant lymphomas and solid tumors that mimic or are associated with epithelioid granulomas are widely recognized in surgical pathology, but have received little attention in the cytopathology literature. In this study the authors present their experience with six such cases in which the presence of granul...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(sici)1097-0142(19980425)84:2<84::aid-cncr
更新日期:1998-04-25 00:00:00
abstract:BACKGROUND:The uptake of thallium-201 (T1-201) in malignant tumors is associated with malignant potential (metastatic potential and proliferative activity). The grade of accumulation of T1-201 in malignant tumors may provide information regarding prognosis. METHODS:A T1-201 single photon emission computed tomography w...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(sici)1097-0142(19970715)80:2<198::aid-cnc
更新日期:1997-07-15 00:00:00
abstract::Two cases of primary non-Hodgkin's lymphomas of the breast were studied with light and electron microscopy. By light microscopy, according to Rappaport's classification, one was a poorly differentiated lymphocytic lymphoma, the other a diffuse histiocytic lymphoma. However, the ultrastructural features of the latter w...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197705)39:5<2025::aid-cncr282039
更新日期:1977-05-01 00:00:00
abstract::Despite relatively high response rates to chemotherapy for ovarian carcinoma, most patients eventually will have progressive disease that will require additional therapy. Most efforts to study such second-line or "salvage" chemotherapy have been single-arm trials of small numbers of patients, which report widely varia...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/cncr.2820710422
更新日期:1993-02-15 00:00:00
abstract:BACKGROUND:The clinical significance of atypical glandular cells of undetermined significance (AGUS) remains poorly understood, and patient management is not standardized. The authors evaluated the rate, qualification, and follow-up (FU) findings of AGUS patients. METHODS:Computerized records from the authors' institu...
journal_title:Cancer
pub_type: 杂志文章
doi:
更新日期:2000-08-25 00:00:00
abstract:BACKGROUND:Human papillomavirus (HPV) DNA has been identified in esophageal carcinomas. However, the incidence of HPV varies significantly in different geographic locations. In the current study, neoplasms from two separate geographic regions were analyzed for the presence of HPV DNA: METHODS:One hundred and ten esoph...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0142(19960815)78:4<704::AID-CNC
更新日期:1996-08-15 00:00:00
abstract:BACKGROUND:Androgen receptor blocking agents have become an established form of therapy for men with disseminated prostate carcinoma. The purpose of this study was to evaluate markers of bone turnover and to measure bone mineral densities (BMD) in men with disseminated prostate carcinoma treated with combined androgen ...
journal_title:Cancer
pub_type: 杂志文章
doi:
更新日期:1998-10-15 00:00:00
abstract::High-dose multiagent chemotherapy followed by autologous marrow rescue was used in the treatment of 13 patients with Stage III or IV childhood tumors. Encouraging results are being obtained in abdominal lymphoma (1/3 complete remissions (CR); rhabdomyosarcoma (2/4 CR); and retinoblastoma (1/2 CR). In neuroblastoma, th...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19820201)49:3<603::aid-cncr28204
更新日期:1982-02-01 00:00:00
abstract::Management of testis cancer in children differs from that in adults due to the histological types and varying tolerances to chemotherapy agents. Embryonal adrenocarcinoma (endodermal sinus tumor, Teilum's tumor) is a tumor of infancy and young children and less aggressive than other testis cancers. Most cases require ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.1980.45.s7.1803
更新日期:1980-04-01 00:00:00
abstract::A retrospective analysis of 74 cases of transitional cell carcinoma of the renal pelvis and ureter treated at this institution over the past 30 years is presented. When nephrectomy alone or incomplete nephroureterectomy was performed, subsequent transitional cell carcinoma developed in 30% of the ureteral stumps. Subs...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197611)38:5<2178::aid-cncr282038
更新日期:1976-11-01 00:00:00
abstract::One hundred fifty-six evaluable patients with metastatic breast cancer were treated with vincristine, Adriamycin and cyclophosphamide alternating at fixed intervals with 5-FU and methotrexate. Immunotherapy with BCG or MER-BCG was administered to all patients in two consecutive treatment programs. Overall objective re...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/1097-0142(19800215)45:4<742::aid-cncr28204
更新日期:1980-02-15 00:00:00
abstract:BACKGROUND:This qualitative study investigated the medical decision-making preferences of adolescent oncology patients and the parental and clinician behaviors that adolescents report to be supportive of their preferred level of decision-making involvement. METHODS:Interviews were conducted with 40 adolescents between...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.29663
更新日期:2015-12-15 00:00:00
abstract::The evidence that various endogenous and exogenous sex hormones play a role in the etiology of breast cancer is reviewed. It is hypothesized that prolonged exposure to normal levels of ovarian estrogens and cyclic progesterone resulting from early menarche and late menopause, and primarily willful nulliparity and late...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(19840201)53:3+<595::aid-cncr2820
更新日期:1984-02-01 00:00:00
abstract:BACKGROUND:To assess the ability of [(18)F]fluorodeoxyglucose (F-18 FDG) positron emission tomography (PET) to predict the viability of residual masses after chemotherapy in patients with metastatic nonseminomatous germ cell tumors (GCT), PET results were compared in a blinded analysis with computed tomography (CT) sca...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.10494
更新日期:2002-05-01 00:00:00
abstract:BACKGROUND:Upfront autologous hematopoietic stem cell transplantation (AHCT) remains an important therapy in the management of patients with multiple myeloma (MM), a disease of older adults. METHODS:The authors investigated the outcomes of AHCT in patients with MM who were aged ≥70 years. The Center for International ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.33171
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:Gastric carcinoids are uncommon, and are unlike carcinoids at other gastrointestinal sites, clinically and pathologically. METHODS:The authors studied specimens from 104 patients with gastric carcinoid, with study emphasis being placed on pathologic features, immunohistochemistry, clinical associations, and...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19940415)73:8<2053::aid-cncr2820
更新日期:1994-04-15 00:00:00
abstract:BACKGROUND:Patients with aggressive non-Hodgkin lymphoma (NHL) develop central nervous system (CNS) progression or recurrence during the course of their disease. Patients with human immunodeficiency virus (HIV)-NHL often develop CNS progression despite the use of prophylaxis. Liposomal cytarabine (DepoCyte) has shown a...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.24922
更新日期:2010-03-15 00:00:00
abstract:BACKGROUND:Patients with metachronous multiple colorectal carcinomas have been reported to have a higher frequency of a family history of colorectal carcinoma, associated colorectal adenomas, and extracolonic malignancies. These clinicopathologic factors also are considered to be related to the development of metachron...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:
更新日期:1999-05-01 00:00:00
abstract:BACKGROUND:It remains unclear whether primary tumor resection benefits patients with metastatic neuroblastoma. The authors assessed the impact of extent and timing of resection on outcome in these patients. METHODS:The authors reviewed the records of 124 patients > 1 year of age at diagnosis of International Neuroblas...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.21566
更新日期:2005-12-15 00:00:00
abstract::The reactivity of serum alpha-fetoprotein (AFP) from 20 patients with hepatocellular carcinoma (HCC) with immobilized lentil lectin was examined and found to be significantly greater (39% +/- 18%) than that of the same protein from seven patients with chronic liver disease (CLD, 11.2% +/- 3.3%), seven with fulminant h...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19910115)67:2<476::aid-cncr28206
更新日期:1991-01-15 00:00:00
abstract::One promising area of current research in chemoprevention is the possibility that micronutrients, including vitamin A analogues, may decrease cancer incidence. The term "vitamin A" refers either to retinol (preformed vitamin A) and its synthetic analogues, or to certain carotenoids (provitamin A), which are converted ...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/1097-0142(19861015)58:8+<1837::aid-cncr282
更新日期:1986-10-15 00:00:00
abstract:BACKGROUND:Nonsteroidal antiinflammatory drugs (NSAIDs) inhibit the development of lung tumors in experimental animals. To the authors' knowledge there are little data regarding whether regular use of NSAIDs reduces the risk of developing lung carcinoma in humans. METHODS:The association between lung carcinoma risk an...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.11242
更新日期:2003-04-01 00:00:00
abstract::The glucocorticoid receptor (GR) quantitation by a whole-cell assay and/or cytosol technique and the in vitro sensitivity to steroids have been assessed in peripheral blood cells from normal donors and patients with chronic lymphatic leukemia (CLL), acute lymphoblastic leukemia (ALL), lymphosarcoma cell leukemia (LSCL...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19820215)49:4<623::aid-cncr28204
更新日期:1982-02-15 00:00:00
abstract:BACKGROUND:Previous data from the National Cancer Data Base have examined time trends in stage of disease, treatment patterns, and survival for selected cancers. The most current (1993) data for breast carcinoma are described here. METHODS:Five Calls for Data have yielded a total of 508,724 breast cancer cases diagnos...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(sici)1097-0142(19961015)78:8<1838::aid-cn
更新日期:1996-10-15 00:00:00
abstract::The relationship between DNA content, clinicopathologic findings, and patient survival in synovial sarcoma was investigated. Patient age at diagnosis (P less than 0.001), tumor size (P less than 0.001), and ploidy status (P less than 0.003) correlated significantly with patient survival. A marginally significant corre...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19900515)65:10<2295::aid-cncr282
更新日期:1990-05-15 00:00:00
abstract::A study of 112 biopsy specimens from Danish oral leukoplakia patients and 145 biopsy specimens from Indian leukoplakia patients revealed a chevron-like keratinization of the epithelium in a number of cases. Clinically, this type of keratinization was often characterized by a pumice-like appearance. The clinical and hi...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19800501)45:9<2330::aid-cncr2820
更新日期:1980-05-01 00:00:00