Prognostic value of the proliferation-related antigen Ki-67 in oligodendrogliomas.

abstract：:Molecular characterization of hepatocellular carcinoma (HCC) has greatly improved our understanding of disease pathogenesis. Mutational analysis, RNA and microRNA expression profiling, and epigenetic characterization have revealed common aberrations in oncogenes and tumor suppressors that correlate with disease biolog...

journal_title：Cancer

authors： Erstad DJ,Fuchs BC,Tanabe KK

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Older women are less likely than younger women to receive definitive care for a new diagnosis of breast cancer, but the reasons are not well understood. Although coordination of referral among specialists is an important component of quality of care, it has not been studied as a factor that contributes to ob...

journal_title：Cancer

authors： Thwin SS,Fink AK,Lash TL,Silliman RA

更新日期：2005-09-01 00:00:00

abstract：:High dose methotrexate followed by citrovorum factor reversal has been utilized in twenty-six patients with advanced cancer. Four of 10 patients with head and neck cancer had an objective response. One of 7 patients with metastatic osteosarcoma to the lungs had stabilization with twenty treatments over 23 months. One ...

journal_title：Cancer

authors： Ambinder EP,Perloff M,Ohnuma T,Biller HF,Holland JF

更新日期：1979-04-01 00:00:00

abstract：BACKGROUND:Although >70% of younger women with nonmetastatic breast cancer (BC) received adjuvant chemotherapy, only approximately 15% to 20% of elderly women with BC received chemotherapy. The decision to treat may be associated with nonmedical factors, such as patient, physician, or practice characteristics. In the c...

journal_title：Cancer

authors： Hershman DL,Buono D,McBride RB,Tsai WY,Neugut AI

更新日期：2009-09-01 00:00:00

abstract：:One-hundred-eighty-eight children up to 16 years of age were randomized in the second National Wilms' Tumor Study (NWTS) with tumors that were confined to the kidney and that had been totally excised (Group I). Most fared well whether treated for six or for 15 months with both actinomycin D (AMD) and vincristine (VCR)...

journal_title：Cancer

authors： D'Angio GJ,Evans A,Breslow N,Beckwith B,Bishop H,Farewell V,Goodwin W,Leape L,Palmer N,Sinks L,Sutow W,Tefft M,Wolff J

更新日期：1981-05-01 00:00:00

abstract：BACKGROUND:Human papillomavirus (HPV) DNA has been identified in esophageal carcinomas. However, the incidence of HPV varies significantly in different geographic locations. In the current study, neoplasms from two separate geographic regions were analyzed for the presence of HPV DNA: METHODS:One hundred and ten esoph...

journal_title：Cancer

authors： Suzuk L,Noffsinger AE,Hui YZ,Fenoglio-Preiser CM

更新日期：1996-08-15 00:00:00

abstract：:Testicular function was studied in 26 men with sarcoma who received adjuvant treatment with doxorubicin, cyclophosphamide, and high-dose methotrexate (with or without radiotherapy). Testicular size, sperm output, and serum FSH, LH and testosterone levels were assessed after treatment. Five of 17 men who received chemo...

journal_title：Cancer

authors： Shamberger RC,Sherins RJ,Rosenberg SA

更新日期：1981-05-15 00:00:00

abstract：BACKGROUND:In regional lymph node metastasis of cutaneous melanoma, the number and volume of involved lymph nodes are the most important prognostic factors. Several studies have revealed that palpation of the lymphatic drainage area(s) and regional lymph nodes has a high rate of false-negative results during follow-up....

journal_title：Cancer

authors： Blum A,Schlagenhauff B,Stroebel W,Breuninger H,Rassner G,Garbe C

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:The development of new chelating agents and radiolabeling protocols is essential to progress in radioimmunotherapy with antibody-chelate conjugates. METHODS:Immunoconjugates of four polyazamacrocycles with N-bonded acetate groups were prepared by conjugation via 2-iminothiolane to Lym-1, a murine antilympho...

journal_title：Cancer

authors： Kukis DL,Diril H,Greiner DP,DeNardo SJ,DeNardo GL,Salako QA,Meares CF

更新日期：1994-02-01 00:00:00

abstract：:The National Wilms' Tumor Study (NWTS) was initiated in 1969. One of its objectives was to modulate treatments according to risk factors to minimize the number and severity of treatment-related short-term and long-term iatrogenic complications. The NWTS has therefore incorporated a Long Term Follow-up Study (LTFS) wit...

journal_title：Cancer

authors： Evans AE,Norkool P,Evans I,Breslow N,D'Angio GJ

更新日期：1991-01-15 00:00:00

abstract：BACKGROUND:Current clinical guidelines recommend earlier, more intensive breast cancer screening with both magnetic resonance imaging (MRI) and mammography for women with breast cancer susceptibility gene (BRCA) mutations. Unspecified details of screening schedules are a challenge for implementing guidelines. METHODS:...

journal_title：Cancer

authors： Cott Chubiz JE,Lee JM,Gilmore ME,Kong CY,Lowry KP,Halpern EF,McMahon PM,Ryan PD,Gazelle GS

更新日期：2013-03-15 00:00:00

abstract：BACKGROUND:Many patients with stage III colon adenocarcinoma do not receive adjuvant chemotherapy despite the proven survival advantage it offers. To enhance the provision of optimal cancer care, patient characteristics associated with not receiving guideline-adherent treatment must be identified among patients with op...

journal_title：Cancer

authors： Winget M,Hossain S,Yasui Y,Scarfe A

更新日期：2010-10-15 00:00:00

abstract：BACKGROUND:In addition to possessing many physiologic functions, human growth hormone-1 (GH1) has been shown in recent in vitro and in vivo experiments to induce malignant disease, including breast carcinoma. The authors investigated the association of breast carcinoma with genetic polymorphisms in the GH1 gene in the ...

journal_title：Cancer

authors： Ren Z,Cai Q,Shu XO,Cai H,Cheng JR,Wen WQ,Gao YT,Zheng W

更新日期：2004-07-15 00:00:00

abstract：BACKGROUND:Prostate carcinoma metastasizes frequently to the skeleton, causing significant morbidity, particularly severe bone pain. Metastatic lesions typically are osteosclerotic, but there is experimental, histologic, and biochemical evidence of increased bone resorption. Furthermore, bone resorption rates appear to...

journal_title：Cancer

authors： Papapoulos SE,Hamdy NA,van der Pluijm G

更新日期：2000-06-15 00:00:00

abstract：BACKGROUND:The authors compared the relative efficacy and safety of low-molecular-weight heparin (LMWH) and unfractionated heparin (UFH) for the initial treatment of venous thromboembolism (VTE) between patients with and without cancer. METHODS:By using Cochrane methodology for systematic reviews, separate meta-analys...

journal_title：Cancer

authors： Akl EA,Rohilla S,Barba M,Sperati F,Terrenato I,Muti P,Bdair F,Schünemann HJ

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:A single-institution, prospective, randomized open trial was performed to compare ondansetron and granisetron in the prevention of chemotherapy-related nausea and vomiting. The effect of antemetic drugs was analyzed indipendently for patients treated with highly emetogenic chemotherapy (Study 1), and those t...

journal_title：Cancer

authors： Gebbia V,Cannata G,Testa A,Curto G,Valenza R,Cipolla C,Latteri MA,Gebbia N

更新日期：1994-10-01 00:00:00

abstract：:Thirty-eight patients with metastatic colorecal carcinoma were treated with 5-fluorouracil (5-FU), and 38 patients were treated with the combination of 5-FU, cyclophosphamide, and methotrexate. In terms of percent response, response duration, and survival there was no apparent difference between the two regimens. Comb...

journal_title：Cancer

authors： Richards F 2nd,Pajak TL,Cooper MR,Spurr CL

更新日期：1975-11-01 00:00:00

abstract：BACKGROUND:Interleukin-2 (IL-2) has immunomodulatory effects, including stimulating the activity of cytotoxic T cells and natural killer cells, and inducing the generation of lymphokine-activated killer cells. The authors investigated whether IL-2 may improve the duration of complete remission (CR) and survival in acut...

journal_title：Cancer

authors： Cortes JE,Kantarjian HM,O'Brien S,Giles F,Keating MJ,Freireich EJ,Estey EH

更新日期：1999-04-01 00:00:00

abstract：:This report is to make the general scientific community aware of availability of human tissues through this network. During the short period of its existence, this network has developed useful procedures for distributing human tumor tissue in a rapid, scientifically useful, cost-effective manner to investigators to wh...

journal_title：Cancer

authors： Clausen KP,Grizzle WE,Livolsi V,Newton WA Jr,Aamodt R

更新日期：1989-04-01 00:00:00

abstract：BACKGROUND:Outcomes for patients with relapsed/refractory acute myeloid leukemia (R/R AML) remain poor. Novel therapies specifically targeting AML are of high interest. Brentuximab vedotin (BV) is an antibody-drug conjugate that is specific for human CD30. In this phase 1 dose escalation study, the authors evaluated th...

journal_title：Cancer

authors： Narayan R,Blonquist TM,Emadi A,Hasserjian RP,Burke M,Lescinskas C,Neuberg DS,Brunner AM,Hobbs G,Hock H,McAfee SL,Chen YB,Attar E,Graubert TA,Bertoli C,Moran JA,Bergeron MK,Foster JE,Ramos AY,Som TT,Vartanian MK,

更新日期：2020-03-15 00:00:00

abstract：:The objective of this study was to evaluate the sensitivity of two methods for determining bone marrow involvement with non-Hodgkin's lymphoma. These methods were histologic review of bone marrow aspirates, and clot sections versus in vitro growth of lymphoma colonies on soft agar. Forty-two bone marrow aspirates were...

journal_title：Cancer

authors： Smith SD,Kisker S,Bush L,Trueworthy RC

更新日期：1984-04-15 00:00:00

abstract：BACKGROUND:Although delay to diagnosis after a breast screening abnormality causes anxiety, its effect on prognosis is unknown. METHODS:Using pooled data from five Canadian organized breast cancer screening programs, the authors used unconditional logistic regression to evaluate the effect of delay to diagnosis on pro...

journal_title：Cancer

authors： Olivotto IA,Gomi A,Bancej C,Brisson J,Tonita J,Kan L,Mah Z,Harrison M,Shumak R

更新日期：2002-04-15 00:00:00

abstract：:The 4F2 antigen is a cell-membrane glycoprotein which arises early in the G0-G1 phases of the cell cycle. This molecule is present in all established human cell lines and most malignant human cells. The authors used an indirect immunophosphatase method to study 50 squamous cell carcinomas of the larynx and ten lymph-n...

journal_title：Cancer

authors： Esteban F,Ruiz-Cabello F,Concha A,Perez Ayala M,Delgado M,Garrido F

更新日期：1990-10-01 00:00:00

abstract：:The nitroblue tetrazolium test (NBT) was evaluated in 111 patients with cancer. Patients were placed into control and "presumed infected" groups. The mean NBT score for the control group, 6.3, was significantly greater than the mean for a group of normal volunteers, 3.1, but the mean score for the "presumed infected" ...

journal_title：Cancer

authors： Lehane DE,Watson S,Lane M

更新日期：1975-05-01 00:00:00

abstract：BACKGROUND:Squamous cell lung carcinoma (SLC), the most frequent type of lung cancer, generally is treated surgically and its prognosis is poor. The only current clinically useful prognostic criterion is lymph node staging (TNM classification). Expression of a novel tumor-associated carbohydrate epitope Gal beta 1-3[Fu...

journal_title：Cancer

authors： Battifora H,Sorensen HR,Mehta P,Ahn C,Niland J,Hage E,Pettijohn DE,Olsson L

更新日期：1992-10-01 00:00:00

abstract：:The pathologic features, clinical presentation and natural history of hepatocellular carcinoma (HCC) developing in the noncirrhotic liver were studied in 61 patients against a background of 63 patients seen concurrently with HCC complicating cirrhosis. Noncirrhotic HCC had a bimodal age distribution, with females pred...

journal_title：Cancer

authors： Smalley SR,Moertel CG,Hilton JF,Weiland LH,Weiand HS,Adson MA,Melton LJ 3rd,Batts K

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND:Recently, invasion of vascular spaces by endometrial carcinoma has received particular attention as a prognostic factor. The goal of the current investigation was to re-examine the effect of vascular invasion on tumor recurrence and survival in patients with endometrial carcinoma. METHODS:Surgical specimens...

journal_title：Cancer

authors： Inoue Y,Obata K,Abe K,Ohmura G,Doh K,Yoshioka T,Hoshiai H,Noda K

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:Specialty of the endoscopist has been related to the postcolonoscopy interval risk of colorectal cancer (CRC). However, the impact of such a difference on the long-term CRC prevention rate by screening colonoscopy is largely unknown. METHODS:A Markov model was constructed to simulate the efficacy and cost o...

journal_title：Cancer

authors： Hassan C,Rex DK,Zullo A,Cooper GS

更新日期：2012-09-15 00:00:00

abstract：BACKGROUND:Most gynecologists determine therapy based on current International Society of Gynecologic Pathologists (ISGP)/World Health Organization classification of endometrial hyperplasia, the reproducibility of which has been questioned. The Gynecologic Oncology Group (GOG) initiated a protocol to assess the efficac...

journal_title：Cancer

authors： Zaino RJ,Kauderer J,Trimble CL,Silverberg SG,Curtin JP,Lim PC,Gallup DG

更新日期：2006-02-15 00:00:00

abstract：BACKGROUND:Tumor-related temporal lobe epilepsy (TLE) has a high likelihood of medical intractability and requires surgical treatment. The aims of this study were to analyze the long-term surgical outcomes of and to present appropriate surgical strategies for tumor-related TLE. METHODS:The clinical data of 87 consecut...

journal_title：Cancer

authors： Phi JH,Kim SK,Cho BK,Lee SY,Park SY,Park SJ,Lee SK,Kim KJ,Chung CK

更新日期：2009-12-15 00:00:00