Abstract:
:The objective of this study was to evaluate the sensitivity of two methods for determining bone marrow involvement with non-Hodgkin's lymphoma. These methods were histologic review of bone marrow aspirates, and clot sections versus in vitro growth of lymphoma colonies on soft agar. Forty-two bone marrow aspirates were studied from 14 children who were without bone marrow involvement at diagnosis. There were seven bone marrow aspirates (from five patients) that had histologic evidence of metastatic lymphoma. Six of these seven specimens formed colonies in vitro. Twenty-nine of 35 histologically negative specimens showed no lymphoma colony growth. However, six histologically negative specimens (from three patients) formed lymphoma colonies. Both the Fisher's exact test and the K statistic were significant, indicating not only an association between histology and in vitro culture results, but also a close agreement. In addition, growth of lymphoma colonies in vitro was associated statistically with both a short duration of complete remission and a short duration of survival.
journal_name
Cancerjournal_title
Cancerauthors
Smith SD,Kisker S,Bush L,Trueworthy RCdoi
10.1002/1097-0142(19840415)53:8<1724::aid-cncr2820subject
Has Abstractpub_date
1984-04-15 00:00:00pages
1724-9issue
8eissn
0008-543Xissn
1097-0142journal_volume
53pub_type
杂志文章相关文献
CANCER文献大全abstract::Three patients had supratentorial malignant brain tumors 7 to 9 years after prophylactic central nervous system (CNS) treatment for acute lymphocytic leukemia or malignant T-cell lymphoma. Therapy was administered at the age of 3 to 8 years and included cranial irradiation (total dose, 1800 to 2400 cGy) and intratheca...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19920501)69:9<2385::aid-cncr2820
更新日期:1992-05-01 00:00:00
abstract::Plasminogen activator is a serine protease which exists in two forms, known as tissue-type plasminogen activator and urokinase-type plasminogen activator. Here, we show that urokinase-type plasminogen activator activity in primary breast carcinomas correlates with both size of tumor and number of axillary nodes with m...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19880801)62:3<531::aid-cncr28206
更新日期:1988-08-01 00:00:00
abstract:BACKGROUND:Breast cancer is the most common cancer and the second leading cause of cancer death among women in the United States; annual breast cancer deaths are exceeded only by those for lung cancer. METHODS:Data from the Surveillance, Epidemiology, and End Results (SEER) program registry of the National Cancer Inst...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19950101)75:1+<257::aid-cncr2820
更新日期:1995-01-01 00:00:00
abstract::In 230 cases of chronic lymphocytic leukemia (CLL), marker analysis was performed with rosette techniques and a panel of xeno-antisera. A monoclonal B-cell proliferation was found in the majority of cases (94%). In most cases, the B-cells carried IgM, with or without IgD. Cytoplasmic immunoglobulin-inclusion bodies we...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19821215)50:12<2826::aid-cncr282
更新日期:1982-12-15 00:00:00
abstract:BACKGROUND:The authors previously identified sperm protein 17 (Sp17) as being expressed in patients with multiple myeloma. The restricted expression of Sp17 in normal tissue makes it an ideal target for tumor vaccine. In the current study, the authors extended their research to include ovarian carcinoma. METHODS:A pai...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.10506
更新日期:2002-05-01 00:00:00
abstract:BACKGROUND:Patients with renal cell carcinoma brain metastases (RCCBM) are frequently excluded from trials and to the authors' knowledge no guidelines currently exist regarding central nervous system (CNS) surveillance or treatment. The objective of the current study was to assist in the creation of treatment guideline...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.23769
更新日期:2008-10-01 00:00:00
abstract::Several decades ago, it was reported that normal and malignant mesothelial cells were transformed into distinct cell types (epithelial to fibrous and fibrous to epithelial) when transferred to in vitro conditions. Those tissue culture data are still cited as evidence supporting that the mesothelial cell has multipoten...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19870801)60:3<334::aid-cncr28206
更新日期:1987-08-01 00:00:00
abstract::Levels of immunoreactive ACTH and calcitonin (CT), as well as CEA, were determined serially in 144 patients with lung cancer and in 62 patients with metastatic carcinoma to the lungs. Patients with neoplasms not involving the lungs, with nonmalignant blood dyscrasias, and with chronic obstructive pulmonary disease wer...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19810515)47:10<2485::aid-cncr282
更新日期:1981-05-15 00:00:00
abstract::Thymic carcinomas are rare malignant neoplasms of the thymic epithelium that are distinguished from the malignant thymomas by the presence of cytologic atypia. Thymic carcinomas may metastasize outside of the thorax and are associated with a very poor prognosis. Complete responses of thymic carcinoma to chemotherapy a...
journal_title:Cancer
pub_type: 临床试验,杂志文章,评审
doi:10.1002/1097-0142(19901115)66:10<2092::aid-cncr282
更新日期:1990-11-15 00:00:00
abstract:BACKGROUND:Prostate-specific antigen (PSA) screening for prostate cancer has high risks of overdiagnosis, particularly among older men, and reports from screening trials indicate that it saves few lives after 11 to 13 years of follow-up. New clinical guidelines recommend against PSA screening for all men or for men age...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.28932
更新日期:2014-11-15 00:00:00
abstract:BACKGROUND:Radiotherapy with its advantage of organ preservation has been used to treat laryngeal cancer (LC) for several decades. However, the impact of radiation on overall survival (OS) in a large population-based study has not been evaluated to date. METHODS:The authors analyzed all patients who had localized and/...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.26357
更新日期:2012-03-01 00:00:00
abstract:BACKGROUND:This study aimed to determine the potential diagnostic value of migration-inhibitory factor (MIF) for gastric cancer in patients presenting with dyspepsia and its prognostic value for gastric cancer. METHODS:A cohort of 97 patients with histologically confirmed gastric adenocarcinoma and 222 patients with d...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.24609
更新日期:2009-12-01 00:00:00
abstract:BACKGROUND:It is unclear whether new treatment modalities have improved the survival of follicular lymphoma patients. Some data show that there has been no improvement in survival in the last 3 decades of the 20th century, whereas the results of recent retrospective studies suggest that evolving therapy has improved th...
journal_title:Cancer
pub_type: 杂志文章,多中心研究
doi:10.1002/cncr.22649
更新日期:2007-05-15 00:00:00
abstract::Five hundred forty three adult patients with acute leukemia were entered on the study designed to: (1) test efficacy of vincristine and prednisone used as primary drug therapy in patients with good prognosis as judged by a circulating blast cell count less than 30,000 cm2; (2) investigate the use of either simultaneou...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19830915)52:6<958::aid-cncr28205
更新日期:1983-09-15 00:00:00
abstract::Flow cytometry studies of the DNA distribution of tumor cells from 92 human breast cancers showed measurable aneuploidy (hyperploidy) in 83 cases (92%). The DNA ploidy values were unimodal in each case, but there was a bimodal distribution for the entire series. One group of tumors had a diploid or near diploid DNA di...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19810815)48:4<980::aid-cncr28204
更新日期:1981-08-15 00:00:00
abstract::When 70 children with disseminated neuroblastoma were treated for 4 months with a course of cyclophosphamide and doxorubicin (Adriamycin) 35 (52%) of 68 assessable patients achieved complete remissions, 13 had partial responses, and 20 had either less than a 50% regression of tumor or evidence of tumor progression. Of...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19811115)48:10<2310::aid-cncr282
更新日期:1981-11-15 00:00:00
abstract:BACKGROUND:In patients with locoregional carcinoma of the esophagus or esophagogastric junction who underwent preoperative chemoradiation, it is unclear whether survival was better predicted by pretherapy clinical stage or by posttherapy pathologic stage. METHODS:The authors studied 235 consecutive patients with preth...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.20916
更新日期:2005-04-01 00:00:00
abstract::One hundred two long-term survivors of childhood cancers with second malignant neoplasms (SMNs) were collected from 10 institutions. Forty-seven cases fulfilling study criteria were studied to determine the risk of developing a SMN in irradiated fields after exposure to various chemotherapeutic agents. The case contro...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197602)37:2+<1177::aid-cncr28203
更新日期:1976-02-01 00:00:00
abstract::There is currently no adequate staging system for cerebral astrocytomas. A scheme for acquiring data that can be used to stage cerebral hemisphere tumors is suggested. This data base, in conjunction with treatment and survival information, may be useful in the management of childhood hemispheric tumors. ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19851001)56:7+<1784::aid-cncr282
更新日期:1985-10-01 00:00:00
abstract::Amyloid as defined by positive Congo red green birefringence and STB red birefringence was observed in the stroma of a tubular carcinoma of minor salivary gland origin. The amyloid exhibited additional histochemical characteristics of immunamyloid, viz., positive DMAB-nitrate and DC-reactions and spontaneous autofluor...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197805)41:5<1836::aid-cncr282041
更新日期:1978-05-01 00:00:00
abstract:BACKGROUND:This year, the 7th edition of the AJCC staging manual has for the first time attributed a unique pTNM staging to intrahepatic cholangiocarcinoma (IHCC) that is intended to replace the 2 Western and ideally also the 2 Eastern systems currently in use. This proposal, which has not yet been validated, was teste...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.25712
更新日期:2011-05-15 00:00:00
abstract:BACKGROUND:Many histologic classifications of thymic epithelial tumors have been reported to date, but to the authors' knowledge, none of them closely reflect the clinical behavior or prognosis of the tumor. Therefore, it is necessary to establish a biologic marker for thymic epithelial tumors. Variants of CD44 may be ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.21046
更新日期:2005-05-15 00:00:00
abstract:BACKGROUND:The poor prognosis reported for patients with high-grade glial neoplasms indicates a need for the development of multimodality therapeutic approaches. The addition of chemotherapy has contributed variably to increased survival. The objective of the current study (Southwest Oncology Group [SWOG] 9016) was to ...
journal_title:Cancer
pub_type: 杂志文章,多中心研究
doi:10.1002/cncr.23585
更新日期:2008-08-01 00:00:00
abstract::During 6375 patient-years of observation, 136 new cancers developed in 117 of 1429 patients with squamous cell carcinoma of the oral cavity. The risk of multiple cancers was excessive in the upper digestive or respiratory tract in patients with squamous cell carcinoma of the oral cavity, accounting for 87 (64%) of the...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19871215)60:12<3083::aid-cncr282
更新日期:1987-12-15 00:00:00
abstract::The medical records of 243 patients admitted over a five-year period with a diagnosis of carcinoma of the cervix were reviewed to determine (1) the frequency of pulmonary metastasis, (2) the relationship between the stage of the primary lesion and the incidence of pulmonary metastasis, and (3) the relationship between...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19820415)49:8<1705::aid-cncr2820
更新日期:1982-04-15 00:00:00
abstract:BACKGROUND:It remains unclear whether health-related quality of life (HRQoL) measurements from patients and staff can be combined with medical data to predict survival in patients with terminal cancer. METHODS:The correlations between survival and potential health-related quality-of-life (HRQoL) prognostic variables w...
journal_title:Cancer
pub_type: 杂志文章,多中心研究
doi:10.1002/cncr.20472
更新日期:2004-09-01 00:00:00
abstract:BACKGROUND:Historically, estrogen receptor (ER) determinations have been made by the ligand-binding assay of tumor homogenates, primarily by the dextran-coated charcoal method (DCC). Immunocytochemical assays (ICA) for ER are more recent and have been executed mostly on frozen sections with the monoclonal antibody H222...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0142(19960615)77:12<2514::AID-C
更新日期:1996-06-15 00:00:00
abstract::A case of diffuse histiocytic lymphoma with sclerosis and chylous pleural and peritoneal effusions spanning four years from onset to diagnosis is presented. Treatment with combination chemotherapy and consolidative radiotherapy resulted in clinical improvement and the patient remains free of disease 14 months after st...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19830601)51:11<2144::aid-cncr282
更新日期:1983-06-01 00:00:00
abstract::Records of 100 consecutive hospitalized cancer patients referred for psychiatric consultation were reviewed. These patients constituted only 5% of those seen by the Psychiatry Consultation Service during the study period. Fifty-six percent of the referred patients were diagnosed as depressed and 40% as having organic ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197809)42:3<1385::aid-cncr282042
更新日期:1978-09-01 00:00:00
abstract::The hemoptysis which occurs following lymphography typically consists of one or more episodes of blood-tinged sputum, and generally requires no treatment. In contradistinction to this "mild" form of hemoptysis, the current report describes a case of hemoptysis following lymphography--hemoptysis so severe as to require...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197902)43:2<482::aid-cncr2820430
更新日期:1979-02-01 00:00:00