Introduction of rituximab in front-line and salvage therapies has improved outcome of advanced-stage follicular lymphoma patients.

abstract：BACKGROUND:Karyotypic abnormalities in sporadic Burkitt lymphoma (BL) have been described extensively. However, to the authors' knowledge, very limited studies have focused on the secondary chromosomal abnormalities in pediatric BL as compared with those of adult BL and on their prognostic impact. METHODS:A retrospect...

journal_title：Cancer

authors： Onciu M,Schlette E,Zhou Y,Raimondi SC,Giles FJ,Kantarjian HM,Medeiros LJ,Ribeiro RC,Pui CH,Sandlund JT

更新日期：2006-09-01 00:00:00

abstract：:An atypical case of adult T-cell leukemia/lymphoma (ATL) associated with human T-cell lymphotropic virus type I (HTLV-I) occurred in a 46-year-old Inupiat Eskimo man with no behavioral risk factors for HTLV-I infection. The case was characterized by lack of atypical circulating lymphocytes, hypercalcemia, and opportun...

journal_title：Cancer

authors： Davidson M,Braziel RM,Lairmore MD,Jacobson S,Sprott JM,Tucker SB,Levine PH,Kaplan JE

更新日期：1993-06-15 00:00:00

abstract：:The accumulation of large amounts of fluid in the pleural space is a common sequela of disseminated carcinomatosis. Traditional management has included therapeutic thoracentesis or the placement of a large bore chest tube for drainage with the subsequent installation of a sclerosing agent in an attempt to achieve pleu...

journal_title：Cancer

authors： Parker LA,Charnock GC,Delany DJ

更新日期：1989-09-15 00:00:00

abstract：BACKGROUND:Postchemotherapy surgery is an essential component in the management of patients with metastatic germ cell tumors (GCT). The authors assessed their institutional experience of retroperitoneal lymph node dissection (RPLND) after multiple chemotherapy regimens for advanced GCT. METHODS:By analyzing the instit...

journal_title：Cancer

authors： Eggener SE,Carver BS,Loeb S,Kondagunta GV,Bosl GJ,Sheinfeld J

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:For patients with stage III through IVB head and neck squamous cell carcinoma (HNSCC), concurrent high-dose cisplatin plus radiation therapy is a widely accepted standard of care. HNSCC tumors that express high levels of vascular endothelial growth factor have been associated with a worse prognosis, and beva...

journal_title：Cancer

authors： Fury MG,Lee NY,Sherman E,Lisa D,Kelly K,Lipson B,Carlson D,Stambuk H,Haque S,Shen R,Kraus D,Shah J,Pfister DG

更新日期：2012-10-15 00:00:00

abstract：BACKGROUND:Fadrozole hydrochloride (CGS 16949A) is a highly potent, nonsteroidal aromatase inhibitor that significantly lowers estrogen levels in postmenopausal women and can be effective therapy for patients with advanced hormone-dependent breast carcinoma. Circulating estradiol, estrone, and estrone sulfate are reduc...

journal_title：Cancer

authors： Costa LA,Kopreski MS,Demers LM,Chinchilli VM,Santen RJ,Harvey HA,Lipton A

更新日期：1999-01-01 00:00:00

abstract：:A new human lymphoblastic lymphoma cell line was established (designated HT-1) from the pleural fluid lymphoma cells of a patient with lymphoblastic lymphoma of T-cell type. The HT-1 cells expressed CD1, CD2, CD3, CD4, CD5, CD7, CD8, CD57, and terminal deoxynucleotidyl transferase (TdT) but lacked B-cell-associated an...

journal_title：Cancer

authors： Abe M,Tasaki K,Nozawa Y,Tominaga K,Fukuhara S,Ohsato T,Wakasa H

更新日期：1992-03-01 00:00:00

abstract：:To determine whether steroid hormone receptor expression is clinically relevant in ovarian cancer, cytoplasmic and nuclear estrogen (ER) and progesterone (PR) receptor levels have been measured and their concentration calculated by Scatchard analysis. Of 89 samples from patients with non-pretreated epithelial ovarian ...

journal_title：Cancer

authors： Harding M,Cowan S,Hole D,Cassidy L,Kitchener H,Davis J,Leake R

更新日期：1990-02-01 00:00:00

abstract：BACKGROUND:Soft tissue sarcomas of the head and neck represent uncommon malignant neoplasms. With the exception of orbital and parameningeal sites, the treatment of sarcomas in the head and neck has not been standardized. The authors used a prospectively collected database of adult soft tissue sarcomas to identify prog...

journal_title：Cancer

authors： Kraus DH,Dubner S,Harrison LB,Strong EW,Hajdu SI,Kher U,Begg C,Brennan MF

更新日期：1994-07-15 00:00:00

abstract：BACKGROUND:The combination of paclitaxel with cisplatin or carboplatin has become the preferred chemotherapy regimen in the treatment of epithelial ovarian carcinoma. Anthracyclines also have activity in this disease. We conducted a Phase II study by using the combination of paclitaxel, cisplatin, and epirubicin for th...

journal_title：Cancer

authors： Papadimitriou CA,Moulopoulos LA,Vlahos G,Voulgaris Z,Kiosses E,Georgoulias N,Gika D,Diakomanolis E,Michalas S,Dimopoulos MA

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:Patients with myeloproliferative neoplasms (MPNs) including polycythemia vera, essential thrombocythemia, and myelofibrosis, are faced with oppressive symptom profiles that compromise daily functioning and quality of life. Among these symptoms, sexuality-related symptoms have emerged as particularly prominen...

journal_title：Cancer

authors： Geyer HL,Andreasson B,Kosiorek HE,Dueck AC,Scherber RM,Martin KA,Butler KA,Harrison CN,Radia DH,Cervantes F,Kiladjian JJ,Reiter A,Birgegard G,Passamonti F,Senyak Z,Vannucchi AM,Paoli C,Xiao Z,Samuelsson J,Mesa RA

更新日期：2016-06-15 00:00:00

abstract：:Until recently the prognosis of childhood non-Hodgkin's lymphoma has been poor. A program of combination chemotherapy and involved area radiotherapy was instituted in the Department of Pediatrics at Roswell Park Memorial Institute in 1971. Thirty-one biopsy proven untreated children entered this study. There were 4 St...

journal_title：Cancer

authors： Brecher ML,Sinks LF,Thomas RR,Freeman AI

更新日期：1978-05-01 00:00:00

abstract：:Plasma TSH and thyroxine levels were measured in 74 early breast cancer patients and 53 with advanced disease, 77 patients with cancer arising in other organs and 67 healthy women of similar age. The mean plasma TSH levels were higher in the breast cancer cases than the other two groups; the difference was statistical...

journal_title：Cancer

authors： Rose DP,Davis TE

更新日期：1978-02-01 00:00:00

abstract：:The ganglioside composition of neuroblastoma samples from 53 patients was determined. Tumor sites included the adrenals (15), and the thoracic (20), abdominal (15), and pelvic (3) areas. Age of the patients at the time of surgery ranged from 1 day to over 10 years and the Stage of the tumors from A to D. Differences i...

journal_title：Cancer

authors： Schengrund CL,Repman MA,Shochat SJ

更新日期：1985-12-01 00:00:00

abstract：:This study is based on 38 patients, each of whom had a malignant lymphoma in which the gonad was the site of the main tumor mass at the time of diagnosis. Histiocytic lymphoma was the predominant type in the 27 male patients; in the 11 female patients, poorly differentiated lymphocytic lymphoma was the most frequent t...

journal_title：Cancer

authors： Paladugu RR,Bearman RM,Rappaport H

更新日期：1980-02-01 00:00:00

abstract：BACKGROUND:Recurrent central neurocytoma is very rare and to the authors' knowledge data regarding its response to chemotherapy currently are not available. METHODS:Three patients with progressive neurocytoma received chemotherapy after their informed consent was obtained. Disease recurred in two patients after surger...

journal_title：Cancer

authors： Brandes AA,Amistà P,Gardiman M,Volpin L,Danieli D,Guglielmi B,Carollo C,Pinna G,Turazzi S,Monfardini S

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:The necessity to develop more effective chemotherapy regimens in advanced nonsmall cell lung carcinoma (NSCLC) prompted the authors to evaluate the paclitaxel-ifosfamide-cisplatin (PIC) combination, developed on the basis of high individual single-agent activity, in vitro synergism, and tolerance as determin...

journal_title：Cancer

authors： Kosmas C,Tsavaris NB,Polyzos A,Kalofonos HP,Sepsas E,Malamos NA,Vadiaka M,Dosios T,Antonopoulos MJ

更新日期：2000-08-15 00:00:00

abstract：:Disparities in minorities' representation in cancer clinical trials have been shown only in adult populations, which suggest that the main causes of these disparities relate to health system-based barriers, including issues of poverty (lack of insurance), poor access to trials, and an inadequate number of clinical tri...

journal_title：Cancer

authors： Colon-Otero G,Smallridge RC,Solberg LA Jr,Keith TD,Woodward TA,Willis FB,Dunn AN

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Although various mechanisms have been recognized as being associated with the development of resistance to imatinib mesylate in vitro and in clinical situations, their relative significance and contributions remain poorly understood, as is the sequence of events leading to the selection of the resistant phen...

journal_title：Cancer

authors： Scappini B,Gatto S,Onida F,Ricci C,Divoky V,Wierda WG,Andreeff M,Dong L,Hayes K,Verstovsek S,Kantarjian HM,Beran M

更新日期：2004-04-01 00:00:00

abstract：:From 1959 to 1986, 24 patients with primary malignant tumors of the trachea received radiotherapy as all or part of treatment. Common presentations included respiratory symptoms in 20 patients and hemoptysis in 15. Thirteen patients had squamous carcinomas with undifferentiated and adenoid cystic cancers in five and f...

journal_title：Cancer

authors： Fields JN,Rigaud G,Emami BN

更新日期：1989-06-15 00:00:00

abstract：BACKGROUND:Achieving a pathologic complete response (pCR) with neoadjuvant chemotherapy (NAC) in patients with muscle-invasive bladder cancer (MIBC) has been associated with improved overall survival (OS). This study was aimed at evaluating the impact of pathologic downstaging (pDS; ie, a pT stage at least 1 stage lowe...

journal_title：Cancer

authors： Martini A,Jia R,Ferket BS,Waingankar N,Plimack ER,Crabb SJ,Harshman LC,Yu EY,Powles T,Rosenberg JE,Pal SK,Vaishampayan UN,Necchi A,Wiklund NP,Mehrazin R,Mazumdar M,Sfakianos JP,Galsky MD

更新日期：2019-09-15 00:00:00

abstract：BACKGROUND:Patients with metachronous multiple colorectal carcinomas have been reported to have a higher frequency of a family history of colorectal carcinoma, associated colorectal adenomas, and extracolonic malignancies. These clinicopathologic factors also are considered to be related to the development of metachron...

journal_title：Cancer

authors： Masubuchi S,Konishi F,Togashi K,Okamoto T,Senba S,Shitoh K,Kashiwagi H,Kanazawa K,Tsukamoto T

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:Supratentorial gangliogliomas (GGs) are rare tumors of the central nervous system and are commonly associated with chronic seizures. To date, only case reports and small series of patients with short-term follow-up have been available for the assessment of the potential of GGs to recur and progress. METHODS...

journal_title：Cancer

authors： Luyken C,Blümcke I,Fimmers R,Urbach H,Wiestler OD,Schramm J

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Colorectal cancer (CRC) develops through the alteration of several critical pathways. This study was aimed at evaluating the influence of critical pathways on survival outcomes for patients with CRC. METHODS:Targeted next-generation sequencing of 40 genes included in the 5 critical pathways of CRC (WNT, P53...

journal_title：Cancer

authors： Lee DW,Han SW,Cha Y,Bae JM,Kim HP,Lyu J,Han H,Kim H,Jang H,Bang D,Huh I,Park T,Won JK,Jeong SY,Park KJ,Kang GH,Kim TY

更新日期：2017-09-15 00:00:00

abstract：BACKGROUND:Low-grade gliomas (LGGs) and low-grade glioneuronal tumors (LGGNTs) diagnosed during the first year of life carry unique clinical characteristics and challenges in management. However, data on the treatment burden, outcomes, and morbidities are lacking. METHODS:A retrospective study of LGGs and LGGNTs diagn...

journal_title：Cancer

authors： Liu APY,Hastings C,Wu S,Bass JK,Heitzer AM,Ashford J,Vestal R,Hoehn ME,Ghazwani Y,Acharya S,Conklin HM,Boop F,Merchant TE,Gajjar A,Qaddoumi I

更新日期：2019-04-01 00:00:00

abstract：:The design of many antineoplastic agents has been based on atom or group replacement in normal metabolites. New dimensions are being added to this approach by the synthesis of transition state, bisubstrate and "suicide" inhibitors. These provide greater potency and in some cases selectivity. Leads for differential sen...

journal_title：Cancer

authors： Handschumacher RE

更新日期：1977-07-01 00:00:00

abstract：BACKGROUND:Curative resection does not guarantee long term survival for the patient with extrahepatic bile duct carcinoma because of the possibility of metastases to the liver (LM). Expression of mucin core protein-1 (MUC1), sialyl-Le(x), and sialosyl-Tn in bile duct carcinoma was determined and compared with LM and pr...

journal_title：Cancer

authors： Takao S,Uchikura K,Yonezawa S,Shinchi H,Aikou T

更新日期：1999-11-15 00:00:00

abstract：BACKGROUND:Increasingly, the quality of life (QOL) of women diagnosed with breast carcinoma is being studied. However, there is little information regarding long term survivors among ethnic minority women. The purpose of this study was to describe the QOL of long term breast carcinoma survivors (BCS) and to examine the...

journal_title：Cancer

authors： Ashing-Giwa K,Ganz PA,Petersen L

更新日期：1999-01-15 00:00:00

abstract：BACKGROUND:Most relapses of Hodgkin's disease (HD) occur within the first 2 years after diagnosis, but they may develop after a longer observation period. The aim of this study was to define the incidence, clinical course, and prognostic factors for late relapse (LR) of Hodgkin's disease. For this purpose, the authors ...

journal_title：Cancer

authors： Garcia-Carbonero R,Paz-Ares L,Arcediano A,Lahuerta J,Bartolome A,Cortes-Funes H

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND:The observed seasonal and geographic variations in the incidence of immunoproliferative small intestinal disease (IPSID) suggest that environmental factors contribute to its pathogenesis. One such environmental factor, the Epstein-Barr virus (EBV), has been associated with other B-cell lymphoproliferative di...

journal_title：Cancer

authors： Baddoura FK,Unger ER,Mufarrij A,Nassar VH,Zaki SR

更新日期：1994-09-15 00:00:00