Small bore catheter drainage and sclerotherapy for malignant pleural effusions.


:The accumulation of large amounts of fluid in the pleural space is a common sequela of disseminated carcinomatosis. Traditional management has included therapeutic thoracentesis or the placement of a large bore chest tube for drainage with the subsequent installation of a sclerosing agent in an attempt to achieve pleural symphysis. An evaluation of all patients treated in this manner during a 4-year period was undertaken to assess the degree of success obtained with a large bore standard chest tube versus a small pigtail catheter. A study group consisting of 20 patients with a total of 24 pleural effusions was treated with drainage and sclerotherapy. In this group, eight of 13 effusions were adequately treated with pigtail catheter drainage and sclerotherapy, compared with four of 11 effusions adequately treated with standard chest tube drainage and sclerotherapy. Although the numbers are small, it appears that pigtail catheter drainage and sclerosis is at least as successful as the more traditional drainage with the standard chest tube.






Parker LA,Charnock GC,Delany DJ




Has Abstract


1989-09-15 00:00:00














  • Simultaneous gastric cancer in monozygotic twins.

    abstract::Monozygotic twins developed gastric cancers that were found almost simultaneously. A 47-year-old man complained of nausea and vomiting; an upper gastrointestinal series and endoscopy revealed advanced gastric cancer invading the serosa. Palliative subtotal gastrectomy was performed. In his asymptomatic twin a gastric ...


    pub_type: 杂志文章,评审


    authors: Matsukura N,Onda M,Tokunaga A,Yoshiyuki T,Shimizu Y,Nishi K,Furukawa K,Yoshiyasu M,Kiyama T,Tanaka N

    更新日期:1988-12-01 00:00:00

  • The usefulness of (18)F-fluorodeoxyglucose positron emission tomography ((18)F-FDG-PET) and a comparison of (18)F-FDG-pet with (67)gallium scintigraphy in the evaluation of lymphoma: relation to histologic subtypes based on the World Health Organization c

    abstract:BACKGROUND:Although studies comparing conventional imaging modalities with (18)F-fluorodeoxyglucose positron emission tomography ((18)F-FDG-PET) for the detection of lymphoma and although the relations between (18)F-FDG-PET and histologic types were reported previously, most studies were not systematic and involved rel...


    pub_type: 杂志文章


    authors: Tsukamoto N,Kojima M,Hasegawa M,Oriuchi N,Matsushima T,Yokohama A,Saitoh T,Handa H,Endo K,Murakami H

    更新日期:2007-08-01 00:00:00

  • Are prognostic factors for local control of breast cancer treated by primary radiotherapy significant for patients treated by mastectomy?

    abstract::Recent follow-up studies of patients with mammary carcinoma treated with breast-conserving primary radiotherapy identified a triad of pathologic features significantly associated with local treatment failure. These unfavorable characteristics of the primary tumor were: poor or undifferentiated nuclear grade; intraduct...


    pub_type: 杂志文章


    authors: Rosen PP,Kinne DW,Lesser M,Hellman S

    更新日期:1986-04-01 00:00:00

  • A multicenter study of the prognosis and treatment of adult brain ependymal tumors.

    abstract:BACKGROUND:The current analysis of outcomes in a large series of adult patients with intracranial ependymal tumors contributes to the characterization of the primary prognostic factors and to the therapeutic management of this rare disease, for which limited information is available in the literature. METHODS:The auth...


    pub_type: 杂志文章,多中心研究


    authors: Reni M,Brandes AA,Vavassori V,Cavallo G,Casagrande F,Vastola F,Magli A,Franzin A,Basso U,Villa E

    更新日期:2004-03-15 00:00:00

  • A nomogram predicting long-term biochemical recurrence after radical prostatectomy.

    abstract:BACKGROUND:Men who undergo radical prostatectomy (RP) are at long-term risk of biochemical recurrence (BCR). In this report, the authors have described a model capable of predicting BCR up to at least 15 years after RP that can adjust predictions according to the disease-free interval. METHODS:Cox regression was used ...


    pub_type: 杂志文章


    authors: Suardi N,Porter CR,Reuther AM,Walz J,Kodama K,Gibbons RP,Correa R,Montorsi F,Graefen M,Huland H,Klein EA,Karakiewicz PI

    更新日期:2008-03-15 00:00:00

  • Adjuvant whole-abdominal radiation therapy in uterine papillary serous carcinoma.

    abstract::Nine patients from 34 to 74 years of age (median, 67 years of age) with uterine papillary serous carcinoma (UPSC) were treated with whole-abdominal radiation therapy (WART) on an adjuvant basis after cytoreductive surgery. All patients were treated with megavoltage photons to an abdominopelvic field to a median dose o...


    pub_type: 杂志文章


    authors: Frank AH,Tseng PC,Haffty BG,Papadopoulos DP,Kacinski BM,Dowling SW,Carcangiu ML,Kohorn EI,Chambers JT,Chambers SK

    更新日期:1991-10-01 00:00:00

  • Image cytometric classification of premalignant breast disease in fine needle aspirates.

    abstract::Image cytometry for the classification of fine needle aspirate (FNA) biopsies was evaluated in samples from 39 women. Eighteen of them had benign lesions, seven had premalignant lesions, nine had carcinoma in situ, and five had carcinoma. The term, premalignant, here refers to lesions with an increased risk of develop...


    pub_type: 杂志文章


    authors: King EB,Chew KL,Duarte L,Hom JD,Mayall BH,Miller TR,Petrakis NL

    更新日期:1988-07-01 00:00:00

  • Adenosarcoma of uterus and ovary: a clinicopathologic study of two cases.

    abstract::We report the clinical and pathologic features of two cases of adenosarcoma. Our first case occurred in the ovary of a 51-year-old woman with extensive pelvic involvement. She was treated vigorously with radiation and chemotherapy and at the present time almost 9 years later the patient is free of disease. This repres...


    pub_type: 杂志文章


    authors: Valdez VA,Planas AT,Lopez VF,Goldberg M,Herrera NE

    更新日期:1979-04-01 00:00:00

  • Target organ disposition and plasma pharmacokinetics of doxorubicin incorporated into albumin microspheres after intrarenal arterial administration.

    abstract::We synthesized doxorubicin (Adriamycin, Adria Laboratories, Columbus, OH)-loaded human albumin microspheres (containing approximately 1% doxorubicin w/w) between 15 and 20 micron in diameter. Intrarenal arterial administration of 99mTC-labeled microspheres demonstrated a high renal entrapment ratio (97% of recovered r...


    pub_type: 杂志文章


    authors: Kerr DJ,Willmott N,McKillop JH,Cummings J,Lewi HJ,McArdle CS

    更新日期:1988-09-01 00:00:00

  • Multidrug resistance proteins in rhabdomyosarcomas: comparison between children and adults.

    abstract:BACKGROUND:Pediatric rhabdomyosarcomas (RMS) have a more advantageous prognosis after multimodality treatment compared with adult RMS, which might be related to a decreased sensitivity to chemotherapy in adults. Resistance to chemotherapy might be conveyed by the multidrug resistance (MDR)-associated proteins P-glycopr...


    pub_type: 杂志文章


    authors: Komdeur R,Klunder J,van der Graaf WT,van den Berg E,de Bont ES,Hoekstra HJ,Molenaar WM

    更新日期:2003-04-15 00:00:00

  • 9p21 Deletion in the diagnosis of malignant mesothelioma in serous effusions additional to immunocytochemistry, DNA-ICM, and AgNOR analysis.

    abstract:BACKGROUND:The diagnosis of malignant mesothelioma (MM) in serous effusions is difficult but may be achieved by the application of adjuvant methods. METHODS:The authors cytologically diagnosed 33 effusions as suspicious or positive for MM cells by using DNA-image cytometry (DNA-ICM), immunocytochemistry and AgNOR anal...


    pub_type: 杂志文章


    authors: Onofre FB,Onofre AS,Pomjanski N,Buckstegge B,Grote HJ,Böcking A

    更新日期:2008-06-25 00:00:00

  • Cancer in collagen disease. A statistical analysis by reviewing the Annual of Pathological Autopsy Cases (Nippon Boken Shuho) in Japan.

    abstract::Cases of systemic lupus erythematosus, systemic sclerosis, periarteritis nodosa, and dermato- and polymyositis autopsied in Japan during a recent, 7-year period (1972-1978) were studied to assess the incidence of cancer as a complication. In comparison with the other three groups, cases of dermato- and polymyositis (D...


    pub_type: 杂志文章


    authors: Okayasu I,Mizutani H,Kurihara H,Yanagisawa F

    更新日期:1984-11-01 00:00:00

  • Prognostic impact of morphometric nuclear grade of endometrial carcinoma.

    abstract:BACKGROUND:The identification of high risk patients with endometrial carcinoma is considered essential for individualized therapy to improve prognosis and avoid overtreatment. The goal of the current study was to investigate the prognostic value of nuclear morphometry, particularly for patients with localized endometri...


    pub_type: 杂志文章


    authors: Salvesen HB,Iversen OE,Akslen LA

    更新日期:1998-09-01 00:00:00

  • Epithelioid hemangioendothelioma of the liver: a clinicopathologic study of 137 cases.

    abstract:BACKGROUND:Epithelioid hemangioendothelioma (EHE) is a rare neoplasm of vascular origin that occurs in the liver and other organs; its etiology is unknown. METHODS:The authors analyzed the clinicopathologic and immunohistochemical features of 137 patients with EHE of the liver in an attempt to identify features that m...


    pub_type: 杂志文章


    authors: Makhlouf HR,Ishak KG,Goodman ZD

    更新日期:1999-02-01 00:00:00

  • Combination therapy of hormone and cytotoxic agents in advanced breast cancer.

    abstract::The effectiveness of combination therapy with diethylstilbestrol, cyclophosphamide, and 5-fluorouracil (DES + CTx + FU) was compared with DES alone or CTx + FU in 87 postmenopausal women with advanced breast cancer. Therapy was randomized according to the tumor estrogen-receptor (ER) status. In 30 patients with ER-ric...


    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Kiang DT,Frenning DH,Gay J,Goldman AI,Kennedy BJ

    更新日期:1981-02-01 00:00:00

  • Thalidomide in the treatment of patients with hepatocellular carcinoma: a phase II trial.

    abstract:BACKGROUND:The treatment of patients with hepatocellular carcinoma (HCC) presents a major challenge, because associated cirrhosis limits the choice of chemotherapeutic agents. However, the abundant vascularity of HCC presents an attractive target for antiangiogenic therapy that potentially may be tolerated by cirrhotic...


    pub_type: 临床试验,杂志文章


    authors: Patt YZ,Hassan MM,Lozano RD,Nooka AK,Schnirer II,Zeldis JB,Abbruzzese JL,Brown TD

    更新日期:2005-02-15 00:00:00

  • Angioimmunoblastic lymphadenopathy. Review of 44 patients with emphasis on prognostic behavior.

    abstract::In order to investigate the relationship between histologic findings and clinical behavior in angioimmunoblastic lymphadenopathy (AILD), 44 patients with AILD were reviewed. These patients comprised 24 men and 20 women with age range from 25 to 84 years of age (median, 64 years). Lymphadenopathy was observed in all pa...


    pub_type: 杂志文章


    authors: Aozasa K,Ohsawa M,Fujita MQ,Kanayama Y,Tominaga N,Yonezawa T,Matsubuchi T,Hirata M,Uda H,Kanamaru A

    更新日期:1989-04-15 00:00:00

  • Prognostic significance of RUNX3 expression in human melanoma.

    abstract:BACKGROUND:RUNX3 is a tumor suppressor that plays important roles in cell proliferation, apoptosis, and metastasis. The authors investigated the role of RUNX3 in melanoma pathogenesis and analyzed the prognostic impact of RUNX3 expression in a large series of melanoma patients. METHODS:Two sets of tissue microarrays w...


    pub_type: 杂志文章


    authors: Zhang Z,Chen G,Cheng Y,Martinka M,Li G

    更新日期:2011-06-15 00:00:00

  • Survivorship programs and care planning.

    abstract::Formal cancer survivorship care is a growing focus internationally. This article provides a broad overview of the national strategies currently in progress for the development of survivorship programs and care plans within the United States and across Europe. The different approaches taken in their implementation, sta...


    pub_type: 杂志文章,评审


    authors: McCabe MS,Faithfull S,Makin W,Wengstrom Y

    更新日期:2013-06-01 00:00:00

  • Human monoclonal antibodies derived from lymph nodes of a patient with breast carcinoma react with MuMTV polypeptides.

    abstract::Nine human hybridoma cell lines were established from a fusion of axillary lymph node lymphocytes of a patient with breast ductal carcinoma with a human lymphoblastoid cell line. The human hybridoma nature of the fusion products was confirmed by chromosomal analysis and HLA typing. The hybridomas are stable over a yea...


    pub_type: 杂志文章


    authors: Shoenfeld Y,Hizi A,Tal R,Smorodinsky NI,Lavie G,Mor C,Schteren S,Mammon Z,Pinkhas J,Keydar T

    更新日期:1987-01-01 00:00:00

  • Combined therapy for metastatic extradural tumors of the spine.

    abstract::The effectiveness of combined modality therapy was studied in 29 patients with metastatic extradural spinal tumor who had had a previous diagnosis of malignancy. Dexamethasone was begun upon suspicion of the diagnosis in a dose of 40 mg daily. Following emergency myelography, in all patients without rapid progression,...


    pub_type: 临床试验,杂志文章


    authors: Marshall LF,Langfitt TW

    更新日期:1977-11-01 00:00:00

  • Symptomatic reduction in free testosterone levels secondary to crizotinib use in male cancer patients.

    abstract:BACKGROUND:Crizotinib is a tyrosine kinase inhibitor active against ALK, MET, and ROS1. We previously reported that crizotinib decreases testosterone in male patients. The detailed etiology of the effect, its symptomatic significance, and the effectiveness of subsequent testosterone replacement have not been previously...


    pub_type: 杂志文章,多中心研究


    authors: Weickhardt AJ,Doebele RC,Purcell WT,Bunn PA,Oton AB,Rothman MS,Wierman ME,Mok T,Popat S,Bauman J,Nieva J,Novello S,Ou SH,Camidge DR

    更新日期:2013-07-01 00:00:00

  • Randomized trial comparing cyclophosphamide, methotrexate, and 5-fluorouracil (CMF) with rotational CMF, epirubicin and vincristine as primary chemotherapy in operable breast carcinoma.

    abstract:BACKGROUND:According to the overview of Early Breast Cancer Trialists' Collaborative Group, anthracycline containing regimens are superior to cyclophosphamide, methotrexate, and 5-fluorouracil (CMF) as adjuvant chemotherapy for breast carcinoma, but no comparative information is available in terms of primary chemothera...


    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验


    authors: Cocconi G,Di Blasio B,Boni C,Bisagni G,Ceci G,Rondini E,Bella M,Leonardi F,Savoldi L,Camisa R,Bruzzi P

    更新日期:2002-07-15 00:00:00

  • Adolescents' preferences for treatment decisional involvement during their cancer.

    abstract:BACKGROUND:This qualitative study investigated the medical decision-making preferences of adolescent oncology patients and the parental and clinician behaviors that adolescents report to be supportive of their preferred level of decision-making involvement. METHODS:Interviews were conducted with 40 adolescents between...


    pub_type: 杂志文章


    authors: Weaver MS,Baker JN,Gattuso JS,Gibson DV,Sykes AD,Hinds PS

    更新日期:2015-12-15 00:00:00

  • Identification of novel mutations by exome sequencing in African American colorectal cancer patients.

    abstract:BACKGROUND:The purpose of this study was to identify genome-wide single nucleotide variants and mutations in African American patients with colorectal cancer (CRC). There is a need of such studies in African Americans, because they display a higher incidence of aggressive CRC tumors. METHODS:We performed whole exome s...


    pub_type: 杂志文章


    authors: Ashktorab H,Daremipouran M,Devaney J,Varma S,Rahi H,Lee E,Shokrani B,Schwartz R,Nickerson ML,Brim H

    更新日期:2015-01-01 00:00:00

  • Postsurgical disparity in survival between African Americans and Caucasians with colonic adenocarcinoma.

    abstract:BACKGROUND:Studies of colorectal adenocarcinoma (CRC) indicate a higher mortality rate for African Americans compared with Caucasians in the United States. In the current study, the authors evaluated the racial differences in survival based on tumor location and pathologic stage between African-American patients and Ca...


    pub_type: 杂志文章


    authors: Alexander D,Chatla C,Funkhouser E,Meleth S,Grizzle WE,Manne U

    更新日期:2004-07-01 00:00:00

  • Phase II trial of recombinant human interleukin-2 and interferon-alpha-2a: implications for the treatment of patients with metastatic melanoma.

    abstract:BACKGROUND:An intensive in-patient Phase II study of continuous infusion recombinant human interleukin-2 (rhIL-2) 3 X 10(6) Roche units (9 MIU/m2)/day plus intramuscular injection of interferon-alpha-2a (rIFN-alpha-2a) 5 x 10(6) U/m2/day, four consecutive days per week, was performed to determine whether four consecuti...


    pub_type: 临床试验,杂志文章


    authors: Eton O,Talpaz M,Lee KH,Rothberg JM,Brell JM,Benjamin RS

    更新日期:1996-03-01 00:00:00

  • Replacement estrogens and risk of gynecologic cancers and breast cancer.

    abstract::The two cancers specific to women for which substantial research on their relationship to exogenous estrogens has been reported are endometrial cancer and breast cancer. With the former, the link to estrogen use is well established. The estrogen use patterns associated with increased risk of endometrial cancer are cha...


    pub_type: 杂志文章,评审


    authors: Hulka BS

    更新日期:1987-10-15 00:00:00

  • Frequent incidence of extrapulmonary sites of initial metastasis in patients with liposarcoma.

    abstract:BACKGROUND:The vast majority of soft tissue sarcomas spread initially to the lungs and then to other sites. The lung has been the most carefully monitored organ system during routine surveillance for a metastasis. Liposarcoma is one of the most common soft tissue sarcomas and has been noted to have extrapulmonary sites...


    pub_type: 杂志文章


    authors: Cheng EY,Springfield DS,Mankin HJ

    更新日期:1995-03-01 00:00:00

  • Specific active immunotherapy in patients with adenocarcinoma of the colon utilizing tumor-associated antigens (TAA). A phase I clinical trial.

    abstract::Twenty-two patients received specific active immunotherapy (TAA vaccine once per month for 3 months), with the duration of follow-up, as of July 1984, ranging from 3 months to 36 months (median, 21 months). Of these, seven had Dukes B2, seven had Dukes C, and eight had Dukes D lesions. All received surgical resection,...


    pub_type: 杂志文章


    authors: Hollinshead A,Elias EG,Arlen M,Buda B,Mosley M,Scherrer J

    更新日期:1985-08-01 00:00:00