Ganglioside composition of human neuroblastomas. Correlation with prognosis. A Pediatric Oncology Group Study.

abstract：:Studies of calcium metabolism in 38 patients with cancer indicated that: 1) intestinal absorption of calcium was reduced in patients with skeletal metastases and in those with hypercalcemia; 2) calcium-47 space (a measurement of bone turnover rate) was high in the patients with skeletal metastases; 3) hypercalcemic pa...

journal_title：Cancer

authors： Coombes RS,Ward MK,Greenberg PB,Hillyard CJ,Tulloch BR,Morrison R,Joplin GF

更新日期：1976-11-01 00:00:00

abstract：BACKGROUND:Irinotecan-based chemotherapy regimens are 1 option for treatment of metastatic colorectal cancer (mCRC). The authors report the safety and efficacy of such regimens in elderly patients using a large phase III trial (bolus, infusional, or capecitabine with camptostar-celecoxib [BICC-C]) cohort. METHODS:In p...

journal_title：Cancer

authors： Jackson NA,Barrueco J,Soufi-Mahjoubi R,Marshall J,Mitchell E,Zhang X,Meyerhardt J

更新日期：2009-06-15 00:00:00

abstract：BACKGROUND:The pretherapy prediction of occult lymph node involvement and the avoidance of otherwise futile and potentially morbid definitive local therapy is paramount in men with newly diagnosed prostate carcinoma. To identify patients with prostate carcinoma who likely have lymph node involvement and would benefit f...

journal_title：Cancer

authors： Polascik TJ,Manyak MJ,Haseman MK,Gurganus RT,Rogers B,Maguire RT,Partin AW

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:Patients with prostate cancer receiving androgen deprivation therapy (ADT) are at risk of sleep disturbance; however, to the authors' knowledge, the mechanisms by which ADT may affect sleep are not well understood. The current study compared objective and subjective sleep disturbance in ADT recipients and co...

journal_title：Cancer

authors： Gonzalez BD,Small BJ,Cases MG,Williams NL,Fishman MN,Jacobsen PB,Jim HSL

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Many patients with stage III colon adenocarcinoma do not receive adjuvant chemotherapy despite the proven survival advantage it offers. To enhance the provision of optimal cancer care, patient characteristics associated with not receiving guideline-adherent treatment must be identified among patients with op...

journal_title：Cancer

authors： Winget M,Hossain S,Yasui Y,Scarfe A

更新日期：2010-10-15 00:00:00

abstract：:In certain experimental tumor models, tumor growth is less pronounced in immune deficient animals. Characteristically, tumors such as the murine B16 melanoma and Lewis lung carcinoma (3LL) are weakly antigenic. We proposed that with such tumors that are weakly antigenic, growth is enhanced by T-cell factors. Young mic...

journal_title：Cancer

authors： Ershler WB,Tuck D,Moore AL,Klopp RG,Kramer KE

更新日期：1988-05-01 00:00:00

abstract：BACKGROUND:The head and neck region is one of the most common locations of rhabdomyosarcoma. Salivary gland involvement is usually secondary to advanced disease, and presentation as a primary salivary gland tumor is very rare. METHODS:Three cases of rhabdomyosarcoma presenting as parotid masses, in 2 boys (ages 3 and ...

journal_title：Cancer

authors： Salomão DR,Sigman JD,Greenebaum E,Cohen MB

更新日期：1998-08-25 00:00:00

abstract：:METHODS. Social class differences in colon cancer survival were studied in 3147 patients with colon cancer diagnosed in Finland from 1979-1982. Of these patients, 2969 were eligible for survival analysis. RESULTS. A clear social class gradient in colon cancer survival was detected. The difference in the age-adjusted r...

journal_title：Cancer

authors： Auvinen A

更新日期：1992-07-15 00:00:00

abstract：BACKGROUND:Children with diffuse brainstem glioma (BSG) commonly undergo novel therapies because their outcome is poor with radiation therapy (RT). Although recent clinical trials using new biologic agents documented intratumoral hemorrhage (IH) among several children with BSG, to the authors' knowledge little is known...

journal_title：Cancer

authors： Broniscer A,Laningham FH,Kocak M,Krasin MJ,Fouladi M,Merchant TE,Kun LE,Boyett JM,Gajjar A

更新日期：2006-03-15 00:00:00

abstract：BACKGROUND:In 1991, the Italian Association for Pediatric Hematology-Oncology and the National Council of Research (CNR) initiated an Italian Cooperative Study (SE 91-CNR Protocol) with the main objective of improving the overall survival (SUR) and the event free survival (EFS) of children and young adults with localiz...

journal_title：Cancer

authors： Rosito P,Mancini AF,Rondelli R,Abate ME,Pession A,Bedei L,Bacci G,Picci P,Mercuri M,Ruggieri P,Frezza G,Campanacci M,Paolucci G

更新日期：1999-08-01 00:00:00

abstract：:Scanning electron microscopy was used to examine the appearances of the colonic mucus layer of rats during chemical carcinogenesis with dimethylhydrazine. The normal colonic mucus layer had a dense homogeneous appearance and provided a complete cover for the mucosal epithelium. At high magnifications tiny fenestration...

journal_title：Cancer

authors： Traynor OJ,Costa NL,Wood CB

更新日期：1983-05-15 00:00:00

abstract：:The exact nature of the association between hormones and the development of breast cancer remains uncertain. Studies of endogenous hormone levels and breast cancer suggest a possible role of estrogens and androgens in the cause of breast cancer. Numerous studies have been conducted to assess the risk of breast cancer ...

journal_title：Cancer

authors： Helzlsouer KJ,Couzi R

更新日期：1995-11-15 00:00:00

abstract：:Lymphocyte cyclic nucleotide content was studied before and after Levamisole administration to cancer patients. Twelve patients with disseminated cancer received 100 mg/m2 on two consecutive days; nine comparable patients with disseminated cancer served as controls. Endogenous cyclic adenosine monophosphate (cAMP) and...

journal_title：Cancer

authors： Lewinski UH,Mavligit GM,Thompson WJ,Hersh EM,Ortez RA

更新日期：1979-10-01 00:00:00

abstract：:A previously unreported high incidence of endoscopically identifiable, diffuse, largely nonulcerative esophagitis, is described in a selected population of Southern African blacks at risk of cancer of the esophagus. This is comparable with findings in similar groups in Iran and China. The incidence of dysplasia and "e...

journal_title：Cancer

authors： Oettlé GJ,Paterson AC,Leiman G,Segal I

更新日期：1986-06-01 00:00:00

abstract：BACKGROUND:The aim was to determine the long-term outcome for patients with FIGO stage IV epithelial ovarian carcinoma (EOC) treated with intraperitoneal (IP) chemotherapy after second-look assessment. METHODS:By using data from a retrospective cohort of 433 patients who received IP therapy after second-look assessmen...

journal_title：Cancer

authors： Zivanovic O,Barakat RR,Sabbatini PJ,Brown CL,Konner JA,Aghajanian CA,Abu-Rustum NR,Levine DA

更新日期：2008-06-15 00:00:00

abstract：:Four courses of ifosfamide with mesna given by intravenous infusions were combined with bolus doxorubicin in a phase II trial to treat patients with breast cancer. Ifosfamide can deplete intracellular glutathione levels and because doxorubicin resistance may be associated with elevated levels of intracellular glutathi...

journal_title：Cancer

authors： Millward MJ,Harris AL,Cantwell BM

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:Disruption of the lymphatic circulation through breast carcinoma-associated axillary lymph node dissection, with or without radiation therapy, reportedly is the most common cause of lymphedema in developed countries. There is no cure for breast carcinoma-associated lymphedema. Although intermittent pneumatic...

journal_title：Cancer

authors： Szuba A,Achalu R,Rockson SG

更新日期：2002-12-01 00:00:00

abstract：:Patients with cancer experience a much higher than expected incidence of thromboembolic disorders, commonly referred as Trousseau syndrome. Although this association has been well documented, the etiology of the hypercoagulable state is not known. The expression on tumor cells of tissue factor (TF), a membrane-bound l...

journal_title：Cancer

authors： Callander NS,Varki N,Rao LV

更新日期：1992-09-01 00:00:00

abstract：:The authors studied 11 pediatric intrathoracic neoplasms that share clinicopathologic features and constitute a specific tumor in children. These neoplasms were intrapulmonary, mediastinal, or pleural-based masses. A common histologic feature was the presence of small, primitive cells with blastematous qualities separ...

journal_title：Cancer

authors： Manivel JC,Priest JR,Watterson J,Steiner M,Woods WG,Wick MR,Dehner LP

更新日期：1988-10-15 00:00:00

abstract：:Malignant struma ovarii is a very rare tumor, consisting of a struma ovarii with malignant change. Only 17 examples with metastases have previously been reported. We present a case which involved both ovaries and produced multiple metastases. Microscopy and ultrastructure were identical to a mixed papillary and follic...

journal_title：Cancer

authors： Pardo-Mindan FJ,Vazquez JJ

更新日期：1983-01-15 00:00:00

abstract：BACKGROUND:Granular cell tumors (GCTs) are uncommon tumors of putative schwannian derivation that are rarely malignant. Although recent studies have addressed a histologic correlation with malignant behavior, similar studies have not been done on cytologic material. METHODS:The authors evaluated 3 malignant GCTs and 1...

journal_title：Cancer

authors： Wieczorek TJ,Krane JF,Domanski HA,Akerman M,Carlén B,Misdraji J,Granter SR

更新日期：2001-12-25 00:00:00

abstract：BACKGROUND:The presence of tumor at the inked margins (IMs) of breast specimens is associated with an increased risk of local recurrence after breast-conserving therapy for invasive breast carcinoma and ductal carcinoma in situ (DCIS). Given the importance of margin status, some have advocated the use of shaved margins...

journal_title：Cancer

authors： Guidi AJ,Connolly JL,Harris JR,Schnitt SJ

更新日期：1997-04-15 00:00:00

abstract：:Of 387 patients who died with lung cancer, 28 cases were reviewed (7.2%) which were clinically undiagnosed. The male:female ratio was 3.6 and mean age was 64 years in the males, 47 years in the females. The most frequent presenting symptoms were neurologic. Prior to death, 21 patients had known or suspected metastatic...

journal_title：Cancer

authors： Clary CF,Michel RP,Wang NS,Hanson RE

更新日期：1983-01-15 00:00:00

abstract：BACKGROUND:Current adjuvant hormone therapy in postmenopausal women with breast cancer is debatable between upfront aromatase inhibitors (AIs) and sequential treatment with tamoxifen. A major concern is the higher rate of early recurrences observed with sequential treatment. The authors conducted a retrospective analys...

journal_title：Cancer

authors： Debled M,MacGrogan G,Brouste V,Mathoulin-Pelissier S,Durand M,Mauriac L

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:Telomeres are protective structures at the ends of linear chromosomes, regulated by a host of associated proteins. When telomeres become dysfunctional, genomic instability ensues. The vast majority of cells undergo apoptosis, although a rare cell may survive and become tumorigenic. METHODS:The authors used ...

journal_title：Cancer

authors： Prescott J,McGrath M,Lee IM,Buring JE,De Vivo I

更新日期：2010-09-15 00:00:00

abstract：BACKGROUND:Questions have existed as to whether residential segregation is a mediator of racial/ethnic disparities in breast cancer care and breast cancer mortality, or has a differential effect by race/ethnicity. METHODS:Data from the Surveillance, Epidemiology, and End Results-Medicare database on white, black, and ...

journal_title：Cancer

authors： Haas JS,Earle CC,Orav JE,Brawarsky P,Keohane M,Neville BA,Williams DR

更新日期：2008-10-15 00:00:00

abstract：:Eighty-one primary ovarian carcinoids and intraovarian metastases from six mid-gut carcinoids were examined for the presence of tumor cells immunoreactive with antisera raised against various neurohormonal peptides, mostly of gastroenteropancreatic (GEP) origin. Twenty of the primary and two of the metastatic carcinoi...

journal_title：Cancer

authors： Sporrong B,Falkmer S,Robboy SJ,Alumets J,Håkanson R,Ljungberg O,Sundler F

更新日期：1982-01-01 00:00:00

abstract：:109 cases of breast cancer were treated by tumorectomy and radiotherapy or radiotherapy alone. Almost 30% with small tumors (T1, T2) were considered inoperable for medical reasons and 70% refused mastectomy. Over the past five years the number of patients refusing mastectomy has definitely increased. 59 cases of surgi...

journal_title：Cancer

authors： Alpert S,Ghossein NA,Stacey P,Migliorelli FA,Efron G,Krishnaswamy V

更新日期：1978-10-01 00:00:00

abstract：BACKGROUND:Recent clinical studies have demonstrated that tumor angiogenesis is a potent prognostic indicator for breast cancer patients. The quantitation of endothelial growth factors is thought to be useful to assess angiogenic phenotype in the tumor. Among the many new endothelial growth factors, vascular endothelia...

journal_title：Cancer

authors： Toi M,Kondo S,Suzuki H,Yamamoto Y,Inada K,Imazawa T,Taniguchi T,Tominaga T

更新日期：1996-03-15 00:00:00

abstract：:Renal cell carcinoma is the most common renal neoplasm associated with pregnancy. The most common presenting symptoms are pain and a palpable mass. Although renal neoplasms in pregnancy are rare, the pregnancy demands special consideration in the methods of diagnostic evaluation. The relationship between renal cell ca...

journal_title：Cancer

authors： Walker JL,Knight EL

更新日期：1986-11-15 00:00:00