Comparing safety and efficacy of first-line irinotecan/fluoropyrimidine combinations in elderly versus nonelderly patients with metastatic colorectal cancer: findings from the bolus, infusional, or capecitabine with camptostar-celecoxib study.

abstract：:A ganglioneuroma with areas of melanosis was resected from the cerebellum of a 6.5-year-old girl. At 2.5 years of age, she was diagnosed to have cerebellar neuroblastoma, which was incompletely resected and then radiated. Histologic, ultrastructural, and immunocytochemical studies undertaken on tissue from both stages...

journal_title：Cancer

authors： de Chadarévian JP,Montes JL,O'Gorman AM,Freeman CR

更新日期：1987-01-01 00:00:00

abstract：:Based on laboratory studies showing enhanced cytotoxicity of floxuridine (FUDR) when used with high doses of leucovorin (LV), a pilot study of FUDR and LV through an implantable pump was initiated for the treatment of hepatic metastases from colorectal cancer. The highest dose of LV that could be administered, taking ...

journal_title：Cancer

authors： Kemeny N,Cohen A,Bertino JR,Sigurdson ER,Botet J,Oderman P

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:The objective of this study was to investigate the potential of virtual microscopy (VM) as an avenue for the delivery of mandatory cytology proficiency tests). METHODS:Three senior cytotechnologists and 2 board-certified cytopathologists participated in 3 virtual proficiency tests. Each set consisted of 10 ...

journal_title：Cancer

authors： Stewart J 3rd,Miyazaki K,Bevans-Wilkins K,Ye C,Kurtycz DF,Selvaggi SM

更新日期：2007-08-25 00:00:00

abstract：BACKGROUND:The importance of the bone marrow microenvironment in multiple myeloma is receiving increasing attention. Recent studies have suggested the importance of cytokine production and cell-cell contact by bone marrow stromal cells in the survival of myeloma cells. METHODS:In the current study, the authors examine...

journal_title：Cancer

authors： Wallace SR,Oken MM,Lunetta KL,Panoskaltsis-Mortari A,Masellis AM

更新日期：2001-04-01 00:00:00

abstract：:The antitumor effect of human leukocyte interferon was investigated on ten patients with malignant brain tumor. In eight cases of primary tumor, IFN alone was administered when their recurrent sign was evident. A dose of 3 X 10(6) IU or 1 X 10(6) IU of IFN was injected intramuscularly two or three times a week in high...

journal_title：Cancer

authors： Hirakawa K,Ueda S,Nakagawa Y,Suzuki K,Fukuma S,Kita M,Imanishi J,Kishida T

更新日期：1983-06-01 00:00:00

abstract：:To determine whether the referral of lung cancer patients to university cancer centers was related to nonclinical factors, the medical charts were reviewed for almost all lung cancer patients diagnosed during the period of 1973-1976 in New Hampshire and Vermont. Greater distance from a cancer center, lower functional ...

journal_title：Cancer

authors： Greenberg ER,Dain B,Freeman D,Yates J,Korson R

更新日期：1988-10-15 00:00:00

abstract：:Fifteen patients developed acute nonlymphocytic leukemia (ANLL) 31 to 182 months following chemotherapy and/or radiotherapy for various malignancies and one non-neoplastic disorder. The ANLL was commonly heralded by a brief preleukemic phase consisting of cytopenias and a variety of morphologic abnormalities. At diagn...

journal_title：Cancer

authors： Foucar K,McKenna RW,Bloomfield CD,Bowers TK,Brunning RD

更新日期：1979-04-01 00:00:00

abstract：:The geographic and demographic data obtained during the Third National Cancer Survey have provided a perspective on etiologic factors and incidence trends for cancers of low frequency. The incidence of cancer of the lip, oral cavity and skin from this survey was compared to similar studies in 1947 and intra-regional p...

journal_title：Cancer

authors： Szpak CA,Stone MJ,Frenkel EP

更新日期：1977-07-01 00:00:00

abstract：:High dose methotrexate followed by citrovorum factor reversal has been utilized in twenty-six patients with advanced cancer. Four of 10 patients with head and neck cancer had an objective response. One of 7 patients with metastatic osteosarcoma to the lungs had stabilization with twenty treatments over 23 months. One ...

journal_title：Cancer

authors： Ambinder EP,Perloff M,Ohnuma T,Biller HF,Holland JF

更新日期：1979-04-01 00:00:00

abstract：BACKGROUND:Patients with locoregional carcinoma of the esophagus or gastroesophageal junction have a poor survival rate after surgery. Preoperative chemotherapy or chemoradiotherapy has not improved the outcome for these patients. Our study was designed to assess the feasibility of preoperative induction combination ch...

journal_title：Cancer

authors： Ajani JA,Komaki R,Putnam JB,Walsh G,Nesbitt J,Pisters PW,Lynch PM,Vaporciyan A,Smythe R,Lahoti S,Raijman I,Swisher S,Martin FD,Roth JA

更新日期：2001-07-15 00:00:00

abstract：:The present study was carried out to investigate a distinctive type of carcinoma of the uterine cervix categorized under the designation as circumscribed carcinoma with lymphocytic infiltration. Grossly this carcinoma is characterized by defined circumscription with a superficial ulceration. A microscropic feature cha...

journal_title：Cancer

authors： Hasumi K,Sugano H,Sakamoto G,Masubuchi K,Kubo H

更新日期：1977-06-01 00:00:00

abstract：BACKGROUND:: Invasive aspergillosis (IA) is a common complication in patients with hematologic malignancies. Patients with solid tumors also are at risk for IA because they may develop neutropenia as a result of chemotherapy and radiotherapy. However, studies of IA in patients with solid tumors are rare. In this study,...

journal_title：Cancer

authors： Yan X,Li M,Jiang M,Zou LQ,Luo F,Jiang Y

更新日期：2009-11-01 00:00:00

abstract：:Renal cell carcinoma (RCC) has remained refractory to substantive change of its natural history despite intervention with a number of therapeutic modalities. Alpha interferons leukocyte interferon alpha [HuIFN-alpha (Le)] and lymphoblastoid interferon alpha [HuIFN-alpha (Ly)] initially were shown to produce regression...

journal_title：Cancer

authors： Neidhart JA

更新日期：1986-04-15 00:00:00

abstract：BACKGROUND:Validation of the prognostic indices for the recurrence-free interval of patients with parotid carcinoma, the development of which was described in a previous report, is needed to be confident of their generalizability and justified prospective use. METHODS:The Dutch Cooperative Group on Head and Neck Cance...

journal_title：Cancer

authors： Vander Poorten VL,Hart AA,van der Laan BF,Baatenburg de Jong RJ,Manni JJ,Marres HA,Meeuwis CA,Lubsen H,Terhaard CH,Balm AJ

更新日期：2003-03-15 00:00:00

abstract：BACKGROUND:While the question of whether the trials of breast cancer screening have resulted in a reduction in breast cancer death has been the subject of much scrutiny, there has been less attention to the reduction in tumor size achieved by screening. METHODS:Size data for invasive breast tumors were assembled from ...

journal_title：Cancer

authors： Michaelson JS,Satija S,Kopans D,Moore R,Silverstein M,Comegno A,Hughes K,Taghian A,Powell S,Smith B

更新日期：2003-11-15 00:00:00

abstract：BACKGROUND:The primary objective of this study was to clarify the significance of p21WAF1/CIP1(p21) gene expression in the tumorgenicity of hepatitis B virus (HBV) and hepatitis C virus (HCV) infected human hepatocelluar carcinoma (HCC). METHODS:The authors performed Northern blot hybridization to compare the p21 mess...

journal_title：Cancer

authors： Kobayashi S,Matsushita K,Saigo K,Urashima T,Asano T,Hayashi H,Ochiai T

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND:The ability to divide subsets of patients with glial neoplasms into prognostic groups currently is limited because only a few clinical and pathologic variables are available. The goal of this investigation was to identify biologic factors of potential prognostic value in patients with cerebral gliomas. METH...

journal_title：Cancer

authors： Ganju V,Jenkins RB,O'Fallon JR,Scheithauer BW,Ransom DT,Katzmann JA,Kimmel DW

更新日期：1994-08-01 00:00:00

abstract：:The cancer experience among 754 first-degree relatives (mothers, fathers, and siblings) of a population-based series of 177 children with soft tissue sarcoma is reported. The current study represents an extension of our earlier work in which the authors found an excess of breast cancer in the mothers of 143 of these c...

journal_title：Cancer

authors： Birch JM,Hartley AL,Blair V,Kelsey AM,Harris M,Teare MD,Jones PH

更新日期：1990-11-15 00:00:00

abstract：:Of 209 Hodgkin's disease patients treated at least 6 months with a five-drug combination of induction chemotherapy and having a complete remission, four patients developed acute myelogenous leukemia (AML) as a second malignant neoplasm. The overall relative risk for development of AML is 185.0 (P less than 0.05) and t...

journal_title：Cancer

authors： Bartolucci AA,Liu C,Durant JR,Gams RA

更新日期：1983-12-15 00:00:00

abstract：:Forty-eight cases of primary insular carcinoid of the ovary were analyzed from a clinicopathologic viewpoint. Sixteen (33%) were associated with preoperative clinical evidence of the carcinoid syndrome. At operation only one ovary was usually enlarged, but in 16% the contralateral ovary was also enlarged by either a d...

journal_title：Cancer

authors： Robboy SJ,Norris HJ,Scully RE

更新日期：1975-08-01 00:00:00

abstract：BACKGROUND:Gene expression profiling (GEP) has been rapidly adopted for early breast cancer and can aid in chemotherapy decision making. Study results regarding racial disparities in testing are conflicting, and may reflect different care settings. To the authors' knowledge, data regarding the influence of provider fac...

journal_title：Cancer

authors： Reeder-Hayes KE,Wheeler SB,Baggett CD,Zhou X,Meng K,Roberts MC,Carey LA,Meyer AM

更新日期：2018-04-15 00:00:00

abstract：:A case of sinus histiocytosis with massive lymphadenopathy (SHML) in which cranial nerve function was impaired is described. Severe paraparesis due to an epidural block at the C2 and C5-T2 levels was also present. Treatment with cytotoxic agents resulted in a dramatic decrease in the size of the involved lymph nodes a...

journal_title：Cancer

authors： Haas RJ,Helmig MS,Prechtel K

更新日期：1978-07-01 00:00:00

abstract：BACKGROUND:A growing body of research has demonstrated that individuals who live in neighborhoods with more severe socioeconomic deprivation may have higher risks for colorectal cancer (CRC). However, previous studies have examined neighborhood socioeconomic status (SES) at only 1 point in time, and it is unclear wheth...

journal_title：Cancer

authors： Zhang D,Matthews CE,Powell-Wiley TM,Xiao Q

更新日期：2019-02-15 00:00:00

abstract：BACKGROUND:Childhood cancer is a highly curable disease when timely diagnosis and appropriate therapy are provided. A negative impact of the coronavirus disease 2019 (COVID-19) pandemic on access to care for children with cancer is likely but has not been evaluated. METHODS:A 34-item survey focusing on barriers to ped...

journal_title：Cancer

authors： Saab R,Obeid A,Gachi F,Boudiaf H,Sargsyan L,Al-Saad K,Javakhadze T,Mehrvar A,Abbas SS,Abed Al-Agele YS,Al-Haddad S,Al Ani MH,Al-Sweedan S,Al Kofide A,Jastaniah W,Khalifa N,Bechara E,Baassiri M,Noun P,El-Houdzi J,K

更新日期：2020-09-15 00:00:00

abstract：BACKGROUND:Quality assurance (QA) of clinical practice is important for any medical specialty. Programs based on the Patterns of Care Study (PCS) have been developed to compare the quality of radiotherapeutic care at individual institutions, with the national average representing the process and outcome of radiotherapy...

journal_title：Cancer

authors： Tanisada K,Teshima T,Ohno Y,Inoue T,Abe M,Ikeda H,Owen JB,Hanks GE,Masuda K,Honke Y

更新日期：2002-07-01 00:00:00

abstract：:Deguelin is a rotenoid compound that exists in abundant quantities in the bark, roots, and leaves of the Leguminosae family of plants. An analysis of evidence from both in vitro and in vivo studies suggests that deguelin displays potent anticancer activity against multiple cancer types and exhibits chemopreventive pot...

journal_title：Cancer

authors： Varughese RS,Lam WS,Marican AABH,Viganeshwari SH,Bhave AS,Syn NL,Wang J,Wong AL,Kumar AP,Lobie PE,Lee SC,Sethi G,Goh BC,Wang L

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:The diagnosis of melanomas at an early stage is associated with improved survival, so the recognition of changes in pigmented skin lesions over time is important. We have developed a computer imaging system with the aim of assisting clinicians in differentiating early melanomas from benign pigmented skin les...

journal_title：Cancer

authors： Aitken JF,Pfitzner J,Battistutta D,O'Rourke PK,Green AC,Martin NG

更新日期：1996-07-15 00:00:00

abstract：BACKGROUND:Several states have opted to expand Medicaid under the Patient Protection and Affordable Care Act (ACA), which offers insurance coverage to low-income individuals up to 138% of the federal poverty level. This expansion of Medicaid to a medically vulnerable population potentially can reduce cancer outcome dis...

journal_title：Cancer

authors： Kim U,Koroukian S,Statler A,Rose J

更新日期：2020-09-15 00:00:00

abstract：BACKGROUND:The development of malignancies in recipients of a cardiothoracic transplant (CTT)--that is, heart, lung, or heart and lung recipients-is of concern. Cutaneous and lymphoproliferative malignancies comprise the two major groups of malignancies encountered. A small subgroup of patients will develop potentially...

journal_title：Cancer

authors： Veness MJ,Quinn DI,Ong CS,Keogh AM,Macdonald PS,Cooper SG,Morgan GW

更新日期：1999-04-15 00:00:00

abstract：:Many clinicians use group support to reduce the psychosocial difficulties of persons with cancer. This study compared the long-term benefits of a thematic counseling model used both as a structure for group support and for counseling patients individually. The thematic model included eight counseling sessions focused ...

journal_title：Cancer

authors： Cain EN,Kohorn EI,Quinlan DM,Latimer K,Schwartz PE

更新日期：1986-01-01 00:00:00