Metastatic carcinoma. The lung as the site for the clinically undiagnosed primary.

abstract：:The most important area in which cancer care and bioethics intersect is in the care of the dying. It is in the shift toward according more control to patients, more choice in the setting in which death will come, and in the willingness to take palliative care and comfort care seriously that bioethics has most usefully...

journal_title：Cancer

authors： Caplan AL

更新日期：2008-10-01 00:00:00

abstract：:A 29-year-old man with metastatic extraadrenal pheochromocytoma developed paraplegia which reversed completely after megavoltage irradiation of the dorsolumbar spine. Later, treated with cyclophosphamide, vincristine, and dacarbazine, he had a temporary decrease in plasma norepinephrine concentration, a partial recalc...

journal_title：Cancer

authors： Siddiqui MZ,Von Eyben FE,Spanos G

更新日期：1988-08-15 00:00:00

abstract：:Chemotherapy for tumors of the central nervous system has a limited efficacy presumably because of restricted blood-brain barrier permeability. The advantage of regional intra-arterial administration of anticancer drugs is an increased uptake during the first passage of the drugs through tumor capillaries. Twenty pati...

journal_title：Cancer

authors： Madajewicz S,Chowhan N,Iliya A,Roque C,Beaton R,Davis R,Fertman S,Meek A,Alvarez O,Pampati M

更新日期：1991-06-01 00:00:00

abstract：BACKGROUND:There have been several recent reports that Wilms tumor gene (WT1) mRNA is overexpressed in many types of neoplasms, and those results suggested that WT1 has oncogenic properties. The objective of the current study was to evaluate the prognostic significance of WT1 mRNA expression in patients with soft tissu...

journal_title：Cancer

authors： Sotobori T,Ueda T,Oji Y,Naka N,Araki N,Myoui A,Sugiyama H,Yoshikawa H

更新日期：2006-05-15 00:00:00

abstract：BACKGROUND:Effective management of symptoms in cancer patients requires early intervention. This study assessed whether the timing of referral to the Supportive Care Center (SCC) and symptom burden outcome varied by race or ethnicity in lung cancer patients who had been seen at a tertiary cancer center. METHODS:Non-Hi...

journal_title：Cancer

authors： Reyes-Gibby CC,Anderson KO,Shete S,Bruera E,Yennurajalingam S

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:A considerable body of evidence supports the concept that a significant number of cutaneous malignant melanomas progress through a precursor lesion or dysplastic melanocytic nevi (DN). Tumor angiogenesis likely plays a critical role in early development of melanoma, and intermediate biomarkers of angiogenesi...

journal_title：Cancer

authors： Einspahr JG,Thomas TL,Saboda K,Nickolof BJ,Warneke J,Curiel-Lewandrowski C,Ranger-Moore J,Duckett L,Bangert J,Fruehauf JP,Alberts DS

更新日期：2007-12-01 00:00:00

abstract：:Twenty-four women with ovarian carcinoma that had metastasized to the liver were treated with intrahepatic infusional therapy. No consistent drug regimen was used. There were no complete responders; however, 33% had a partial response. All responses were noticed after the first course of therapy. The median length of ...

journal_title：Cancer

authors： Malone JM Jr,Gershenson DM,Carrasco CH,Charansangavej C,Copeland LJ,Larson DM,Kavanagh JJ,Edwards CL,Wallace S

更新日期：1987-06-01 00:00:00

abstract：BACKGROUND:The objective of this study was to evaluate the correlation between intratumoral blood flow as assessed by color Doppler ultrasound with stage, tumor grade, depth of invasion, and lymph node metastasis in endometrial carcinoma and determine its clinical usefulness. METHODS:Sixty-six patients with endometria...

journal_title：Cancer

authors： Cheng WF,Chen TM,Chen CA,Wu CC,Huang KT,Hsieh CY,Hsieh FJ

更新日期：1998-05-15 00:00:00

abstract：BACKGROUND:Mycosis fungoides (MF) is predominantly a disease of older patients, but occasionally occurs in children. The aims of the current study were to describe the clinical presentation, pathologic features, and disease progression (DP) in patients who developed MF before age 16 years. METHODS:A retrospective stud...

journal_title：Cancer

authors： Wain EM,Orchard GE,Whittaker SJ,Spittle M Sc MF,Russell-Jones R

更新日期：2003-11-15 00:00:00

abstract：:This communication reports four patients treated with the anthracycline adriamycin and irradiation either concurrently or sequentially, who demonstrated apparent augumentation of radiation reactions. Two of these patients demonstrated the so-called "recall" phenomenon. ...

journal_title：Cancer

authors： Cassady JR,Richter MP,Piro AJ,Jaffe N

更新日期：1975-09-01 00:00:00

abstract：BACKGROUND:In spite of many reports, it remains unclear whether the presence of tumor cells in circulating blood flow predicts a poor prognosis. METHODS:Competitive seminested reverse transcriptase-polymerase chain reaction (RT-PCR), a technique for the quantitative detection of tumor cells, was applied to detect the ...

journal_title：Cancer

authors： Sadahiro S,Suzuki T,Tokunaga N,Yurimoto S,Yasuda S,Tajima T,Makuuchi H,Murayama C,Matsuda K

更新日期：2001-09-01 00:00:00

abstract：:Recent studies have indicated that the nuclear DNA content of certain malignant neoplasms can be used as an adjunct in predicting their biologic behavior. The DNA content of 99 ovarian carcinomas was determined by flow cytometric analysis of nuclei obtained from paraffin-embedded tissue. Of the 99 tumors, 51 were dipl...

journal_title：Cancer

authors： Brescia RJ,Barakat RA,Beller U,Frederickson G,Suhrland MJ,Dubin N,Demopoulos RI

更新日期：1990-01-01 00:00:00

abstract：:The unique case of a 60-year-old patient with a non-Hodgkin's B-cell lymphoma of the lymphoplasmacytic type and three associated monoclonal proteins, is described. The patient also exhibited various autoimmune phenomena that were consistent with the diagnoses of Sjögren's syndrome and autoimmune thyroiditis. The evolu...

journal_title：Cancer

authors： Berg AR,Weisenburger DD,Linder J,Armitage JO

更新日期：1986-05-01 00:00:00

abstract：:From 1949 to 1972, 4732 patients with carcinomas of the lung were seen. Of these, 118 patients were found alive at 10 years from their initial diagnosis and treatment. This number represents only 2.5% of all lung cancers seen because many have been lost to follow-up within the first ten years, and their true status is...

journal_title：Cancer

authors： Temeck BK,Flehinger BJ,Martini N

更新日期：1984-03-15 00:00:00

abstract：BACKGROUND:Outcomes for patients with relapsed/refractory acute myeloid leukemia (R/R AML) remain poor. Novel therapies specifically targeting AML are of high interest. Brentuximab vedotin (BV) is an antibody-drug conjugate that is specific for human CD30. In this phase 1 dose escalation study, the authors evaluated th...

journal_title：Cancer

authors： Narayan R,Blonquist TM,Emadi A,Hasserjian RP,Burke M,Lescinskas C,Neuberg DS,Brunner AM,Hobbs G,Hock H,McAfee SL,Chen YB,Attar E,Graubert TA,Bertoli C,Moran JA,Bergeron MK,Foster JE,Ramos AY,Som TT,Vartanian MK,

更新日期：2020-03-15 00:00:00

abstract：BACKGROUND:Patients with renal masses are at risk for having or developing chronic kidney disease (CKD) stage 3 (glomerular filtration rate [GFR] <60 mL per minute/1.73 m2). In this study, the authors investigated whether the Screening for Occult Renal Disease (SCORED) model could identify patients with renal masses wh...

journal_title：Cancer

authors： Lucas SM,Nuss G,Stern J,Lotan Y,Sagalowsky AI,Cadeddu JA,Raj GV

更新日期：2008-11-15 00:00:00

abstract：BACKGROUND:The Akt/mammalian target of rapamycin (mTOR) pathway mediates cell survival and proliferation and contributes to tumor progression. Soft tissue leiomyosarcoma continues to show poor prognosis, and little is known about its mechanisms of tumor progression. Here the authors investigated the significance of act...

journal_title：Cancer

authors： Setsu N,Yamamoto H,Kohashi K,Endo M,Matsuda S,Yokoyama R,Nishiyama K,Iwamoto Y,Dobashi Y,Oda Y

更新日期：2012-03-15 00:00:00

abstract：:In order to validate xenografted small cell lung carcinomas (SCLC) for biological studies, the authors established 12 lung neuroendocrine (NE) tumors (eight typical SCLC and four atypical NE tumors [ANE]) by heterotransplantation onto nude mice. Their characterization was performed using serial ultrastructural, enzyma...

journal_title：Cancer

authors： Brambilla E,Jacrot M,Batandier C,Brichon PY,Morel F,Nagy-Mignotte H,Paramelle B,Brambilla C

更新日期：1989-09-15 00:00:00

abstract：BACKGROUND:The diagnosis of low-grade squamous intraepithelial lesion (LSIL), cannot exclude high-grade squamous intraepithelial lesion (LSIL-H) was not included in the 2001 Bethesda System. It is used in some institutions to diagnose cases that fulfill criteria for both the diagnosis of LSIL and atypical squamous cell...

journal_title：Cancer

authors： Alsharif M,Kjeldahl K,Curran C,Miller S,Gulbahce HE,Pambuccian SE

更新日期：2009-04-25 00:00:00

abstract：BACKGROUND:Current salvage therapy for recurrent high-risk neuroblastoma is rarely curative. Assessment of the effectiveness of new, primarily cytostatic agents requires the redefinition of study endpoints to reflect disease stabilization rather than tumor response or regression. The intervals of disease control in the...

journal_title：Cancer

authors： Santana VM,Furman WL,McGregor LM,Billups CA

更新日期：2008-06-15 00:00:00

abstract：:To determine the efficacy of adjuvant chemotherapy in patients with advanced head and neck squamous carcinoma, the National Cancer Institute initiated a multi-institutional, prospective randomized trial termed the Head and Neck Contracts Program. Between 1978 and 1982, 462 patients with resectable Stage III or IV canc...

journal_title：Cancer

authors：

更新日期：1987-08-01 00:00:00

abstract：:Oat-cell carcinoma of the thymus gland is exceedingly rare as a primary lesion, and only a few cases have been reported. We report a case in which a neoplasm interpreted as an oat-cell carcinoma was intimately associated with and arose in transition from a carcinoid tumor of the thymus. Ultrastructural features of thi...

journal_title：Cancer

authors： Wick MR,Scheithauer BW

更新日期：1982-04-15 00:00:00

abstract：BACKGROUND:Rapid tumor growth is caused by angiogenesis factors, growth factors, etc. We previously reported a possible connection between nitric oxide (NO) and enhanced vascular permeability in solid tumor. In the present experiment, the role of NO in solid tumor pathology was further investigated in animal tumor. ME...

journal_title：Cancer

authors： Doi K,Akaike T,Horie H,Noguchi Y,Fujii S,Beppu T,Ogawa M,Maeda H

更新日期：1996-04-15 00:00:00

abstract：:Canada is a westernized, market-economy nation with a publicly funded health care and cancer control system and has health indices reflective of a high-resource economy. Provision of health services is in accord with the Canada Health Act and is implemented through federal, provincial, and territorial relations wherei...

journal_title：Cancer

authors： Sutcliffe SB

更新日期：2011-05-15 00:00:00

abstract：BACKGROUND:In the past 4 years, the weekly 24-hour infusion of high dose 5-fluorouracil (5-FU) and leucovorin in the treatment of patients with advanced gastric carcinoma has been prospectively studied at the authors' institution. This has enabled them to explore the possibility that the level of expression of thymidyl...

journal_title：Cancer

authors： Yeh KH,Shun CT,Chen CL,Lin JT,Lee WJ,Lee PH,Chen YC,Cheng AL

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:We previously reported that a single prostate-specific antigen (PSA) measured at ages 44-50 was highly predictive of subsequent prostate cancer diagnosis in an unscreened population. Here we report an additional 7 years of follow-up. This provides replication using an independent data set and allows estimate...

journal_title：Cancer

authors： Lilja H,Cronin AM,Dahlin A,Manjer J,Nilsson PM,Eastham JA,Bjartell AS,Scardino PT,Ulmert D,Vickers AJ

更新日期：2011-03-15 00:00:00

abstract：BACKGROUND:Spouses of cancer survivors are at an increased risk of poor mental health outcomes but are known to underuse supportive services. The objective of the current study was to determine how the health and health care use of cancer survivors were associated with depression and anxiety-related health care use in ...

journal_title：Cancer

authors： Litzelman K,Choi H,Maher ME,Harnish A

更新日期：2020-12-08 00:00:00

abstract：:Adenoid cystic carcinoma (ACC) of the breast is a rare histologic type of breast cancer associated with a good prognosis. A woman who earlier had a pulmonary metastasis surgically resected 6 years postmastectomy developed clinically symptomatic bleeding from a renal metastasis 12 years postmastectomy. An atypical angi...

journal_title：Cancer

authors： Herzberg AJ,Bossen EH,Walther PJ

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND:Cisplatin, 5-flourouracil (5-FU), and leucovorin (PFL) chemotherapy has been reported to be effective in the treatment of cancers but severe mucositis or neutropenia are dose limiting toxicities. This Phase II study evaluated the anticancer effect and the toxicities of a new weekly 24-hour infusional PFL che...

journal_title：Cancer

authors： Chi KH,Chan WK,Shu CH,Law CK,Chen SY,Yen SH,Chen KY

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND:Cisplatin has been reported to enhance the cell-killing effect of radiation. The current study was conducted to evaluate the efficacy and toxicity of radiotherapy combined with cisplatin in patients with locally advanced pancreatic carcinoma. METHODS:Forty-one patients with pancreatic carcinoma that was unr...

journal_title：Cancer

authors： Okusaka T,Okada S,Tokuuye K,Wakasugi H,Saisho H,Ishikawa O,Matsuno S,Sato T,Sato K,Non-surgical Treatment Group for Pancreatic Cancer in Japan.

更新日期：2001-04-01 00:00:00