Clinical significance of the diagnosis of low-grade squamous intraepithelial lesion, cannot exclude high-grade squamous intraepithelial lesion.

abstract：:Four hundred forty-seven women attending a breast clinic because of either suspicious lesions, anxiety about breast cancer, follow-up after the removal of a benign breast lesion, or a family history of breast cancer had a routine test for percentage of ferritin-bearing lymphocytes ( FBL ) in their peripheral blood. Am...

journal_title：Cancer

authors： Moroz C,Kan M,Chaimof C,Marcus H,Kupfer B,Cuckle HS

更新日期：1984-07-01 00:00:00

abstract：BACKGROUND:Heat shock protein 60 (Hsp60) is a chaperonin involved in tumorigenesis, but its participation in tumor development and progression is not well understood and its value as a tumor biomarker has not been fully elucidated. In the current study, the authors presented evidence supporting the theory that Hsp60 ha...

journal_title：Cancer

authors： Campanella C,Rappa F,Sciumè C,Marino Gammazza A,Barone R,Bucchieri F,David S,Curcurù G,Caruso Bavisotto C,Pitruzzella A,Geraci G,Modica G,Farina F,Zummo G,Fais S,Conway de Macario E,Macario AJ,Cappello F

更新日期：2015-09-15 00:00:00

abstract：BACKGROUND:The experience of one institution in treating soft tissue sarcomas of the head and neck in a pediatric population is presented. METHODS:Case materials of 134 patients younger than 20 years who were referred to the University of Texas M. D. Anderson Cancer Center between 1970 and 1989 for treatment of sarcom...

journal_title：Cancer

authors： Lyos AT,Goepfert H,Luna MA,Jaffe N,Malpica A

更新日期：1996-01-01 00:00:00

abstract：:Primary splenic angiosarcomas are rare neoplasms. The diagnosis can only be made at surgery. Splenectomy prior to rupture prolongs survival. An unusual case report is presented and the literature reviewed. ...

journal_title：Cancer

authors： Smith VC,Eisenberg BL,McDonald EC

更新日期：1985-04-01 00:00:00

abstract：BACKGROUND:The incidence of rectal cancer in the United States in young patients is considered to be low. Underestimating this incidence may result in a failure to diagnose younger patients with rectal cancer in a timely manner. METHODS:The authors conducted a retrospective cohort study using Surveillance, Epidemiolog...

journal_title：Cancer

authors： Meyer JE,Narang T,Schnoll-Sussman FH,Pochapin MB,Christos PJ,Sherr DL

更新日期：2010-09-15 00:00:00

abstract：BACKGROUND:There is considerable evidence that one of the strongest risk factors for breast carcinoma can be assessed from the mammographic appearance of the breast. However, the magnitude of the risk factor and the reliability of the prediction depend on the method of classification. Subjective classification requires...

journal_title：Cancer

authors： Byng JW,Yaffe MJ,Lockwood GA,Little LE,Tritchler DL,Boyd NF

更新日期：1997-07-01 00:00:00

abstract：:Two unusual cases of angioimmunoblastic lymphadenopathy with dysproteinemia (AILD), with progression to immunoblastic lymphoma (IL) and prominent gastric involvement are presented, and detailed immunohistologic studies described. In one case, Bence Jones proteinuria of the kappa type was observed during the course of ...

journal_title：Cancer

authors： Bauer TW,Mendelsohn G,Humphrey RL,Mann RB

更新日期：1982-11-15 00:00:00

abstract：BACKGROUND:The objective of this study was to investigate the potential of virtual microscopy (VM) as an avenue for the delivery of mandatory cytology proficiency tests). METHODS:Three senior cytotechnologists and 2 board-certified cytopathologists participated in 3 virtual proficiency tests. Each set consisted of 10 ...

journal_title：Cancer

authors： Stewart J 3rd,Miyazaki K,Bevans-Wilkins K,Ye C,Kurtycz DF,Selvaggi SM

更新日期：2007-08-25 00:00:00

abstract：:Exposure of tumor cells to reduced folates before or with the fluoropyrimidines, 5-fluorouracil or 5-fluoro-2'deoxyuridine, results in a substantial increase in the activity of these drugs. Available evidence suggests that the mechanism of this synergism is a kinetic stabilization of complex formed between thymidylate...

journal_title：Cancer

authors： Morgan RG

更新日期：1989-03-15 00:00:00

abstract：BACKGROUND:Aggressive angiomyxoma is an uncommon mesenchymal tumor that preferentially involves the pelvic and perineal regions of females. Since its initial description in 1983, approximately 65 cases have been reported in the English literature. METHODS:The clinical and pathologic features of 29 cases of aggressive ...

journal_title：Cancer

authors： Fetsch JF,Laskin WB,Lefkowitz M,Kindblom LG,Meis-Kindblom JM

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND:Granular cell tumors (GCTs) are uncommon tumors of putative schwannian derivation that are rarely malignant. Although recent studies have addressed a histologic correlation with malignant behavior, similar studies have not been done on cytologic material. METHODS:The authors evaluated 3 malignant GCTs and 1...

journal_title：Cancer

authors： Wieczorek TJ,Krane JF,Domanski HA,Akerman M,Carlén B,Misdraji J,Granter SR

更新日期：2001-12-25 00:00:00

abstract：:Forty-nine specimens of carcinoma of the breast were analyzed for estrogen receptor content using the sucrose gradient method and a histochemical method using a conjugate of estradiol (6-BSA-Fluor-CMO-17 beta-estradiol). The specimens analyzed by the histochemical method were graded for fluorescent intensity, percenta...

journal_title：Cancer

authors： Panko WB,Mattioli CA,Wheeler TM

更新日期：1982-05-15 00:00:00

abstract：BACKGROUND:The overexpression of HER-2 occurs in a minority of patients with nonsmall cell lung carcinoma. Trastuzumab, which is a monoclonal antibody to HER-2, is an effective treatment in some women with breast carcinomas that overexpress HER-2, as demonstrated by immunohistochemistry. The objective of this Phase II ...

journal_title：Cancer

authors： Clamon G,Herndon J,Kern J,Govindan R,Garst J,Watson D,Green M,Cancer and Leukemia Group B.

更新日期：2005-04-15 00:00:00

abstract：:Forty-three patients with evaluable metastatic breast cancer refractory to hormonal agents and extensive combination chemotherapy including doxorubicin were treated with mitomycin, 20 mg/m2 intravenously every 6 weeks. There were five partial responses (12%) and three minor responses (7%), with a mean time to progress...

journal_title：Cancer

authors： Pasterz RB,Buzdar AU,Hortobagyi GN,Blumenschein GR

更新日期：1985-11-15 00:00:00

abstract：BACKGROUND:Systemic anticancer therapies can produce acute and chronic organ damage, but the eye is usually considered a protected site. Nonetheless, the oculo-visual system has a potentially high degree of sensitivity to toxic substances. Ocular toxicity induced by cancer chemotherapy includes a broad spectrum of diso...

journal_title：Cancer

authors： al-Tweigeri T,Nabholtz JM,Mackey JR

更新日期：1996-10-01 00:00:00

abstract：:Ovarian cancer disproportionately affects women 65 years of age and older who are likely to have concomitant changes in physical ability, physiological functioning, and other chronic conditions associated with advancing age. The National Institute on Aging, National Cancer Institute, and the American Cancer Society co...

journal_title：Cancer

authors： Yancik R,Moore TD,Martin G,Obrams GI,Reed E

更新日期：1993-01-15 00:00:00

abstract：BACKGROUND:Although acquired somatic mutations presumably are crucial in carcinogenesis, nothing is known about the chromosome aberrations of bilateral breast carcinomas. METHODS:Eighteen specimens from 16 bilateral carcinomas were analyzed cytogenetically. The banding analysis was supplemented with fluorescence in si...

journal_title：Cancer

authors： Pandis N,Teixeira MR,Gerdes AM,Limon J,Bardi G,Andersen JA,Idvall I,Mandahl N,Mitelman F,Heim S

更新日期：1995-07-15 00:00:00

abstract：BACKGROUND:The influence of various clinicopathologic features on survival of patients with papillary thyroid carcinoma has been examined. In particular, histologic grade, which was obtained by a combined assessment of nuclear atypia, tumor necrosis, and vascular invasion (VAN score) was studied. According to this, his...

journal_title：Cancer

authors： Akslen LA

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:The activation of the clotting-fibrinolytic system in cancer patients is common and represents an unfavorable clinical sign. D-dimer (DD) is a sensitive marker of fibrinolysis. METHODS:The current study comprised 826 new lung carcinoma patients seen consecutively in a single institution over a 10-year perio...

journal_title：Cancer

authors： Buccheri G,Torchio P,Ferrigno D

更新日期：2003-06-15 00:00:00

abstract：BACKGROUND:Although thin cutaneous melanomas generally have a favorable prognosis, in some cases they may undergo progression. The current study was undertaken to identify variables that may predict a more aggressive clinical outcome in these patients. In addition to classic clinicopathologic features, the authors test...

journal_title：Cancer

authors： Massi D,Franchi A,Borgognoni L,Reali UM,Santucci M

更新日期：1999-03-01 00:00:00

abstract：:Hereditary cancer represents approximately 5-10% of the total cancer burden and may account for 60,000 to 120,000 new cancer occurrences this year in the United States. New developments in molecular genetics and the cloning of cancer-prone genes have intensely fueled interest in dealing with hereditary forms of cancer...

journal_title：Cancer

authors： Lynch HT,Watson P,Shaw TG,Lynch JF,Harty AE,Franklin BA,Kapler CR,Tinley ST,Liu B

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:Hypercalcemia of malignancy (HM) is one of the commonest metabolic complications associated with cancer. Plasma parathyroid hormone-related peptide (PTH-rp) is known to cause hypercalcemia in the vast majority of patients with HM. METHODS:Fifty-two patients with HM were treated with a single infusion of 60 ...

journal_title：Cancer

authors： Wimalawansa SJ

更新日期：1994-04-15 00:00:00

abstract：:The ultrastructure of a human pineoblastoma is described. Tumor cells formed nests, palisading row and rosettes. Cells within nests were undifferentiated. Palisade and rosette forming cells had polarized cytoplasms and showed signs of differentiation and surface membrane specialization which included surface end-bulb-...

journal_title：Cancer

authors： Kline KT,Damjanov I,Katz SM,Schmidek H

更新日期：1979-11-01 00:00:00

abstract：BACKGROUND:The objective of this study was to determine the potential economic implications resulting from using exemestane (EXE), a new steroidal, irreversible aromatase inactivator, compared with megestrol acetate (MA) in patients with advanced breast carcinoma. METHODS:The model used the clinical results from the m...

journal_title：Cancer

authors： Hillner BE,Radice D

更新日期：2001-02-01 00:00:00

abstract：:A case of transfusion-induced graft-versus-host disease (GVHD) occurring in a 31-year-old female with Hodgkin's disease in complete remission is reported. Clinical features are similar to 19 other reported cases of transfusion-induced GVHD associated with malignant lymphoma. The lack of relationship with underlying hi...

journal_title：Cancer

authors： Spitzer TR,Cahill R,Cottler-Fox M,Treat J,Sacher R,Deeg HJ

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND:Selective neck dissection (SND) is a mainstay of head and neck cancer treatment. A common sequela is shoulder syndrome from spinal accessory nerve (SAN) trauma. Extensive dissection in neck levels 2 and 5 leads to SAN dysfunction. However, it is not known whether limited level 2 dissection reduces SAN injury...

journal_title：Cancer

authors： Dziegielewski PT,McNeely ML,Ashworth N,O'Connell DA,Barber B,Courneya KS,Debenham BJ,Seikaly H

更新日期：2020-04-01 00:00:00

abstract：:Two patients with superior vena cava syndrome (SVCS) recurring after maximum-tolerance radiation were treated by placing a Gianturco expandable wire stent (GEWS) into the obstructed superior vena cava. The SVCS symptoms rapidly disappeared and good short-term (6 months) palliation was achieved. GEWS placement is a pro...

journal_title：Cancer

authors： Rösch J,Bedell JE,Putnam J,Antonovic R,Uchida B

更新日期：1987-09-15 00:00:00

abstract：:Almost all patients with prostatic cancer will eventually escape the control of the first-line endocrine therapy and relapse. This escape is attributed to selecting and/or cloning preexisting or de novo appearing hormone-independent or resistant cell lines and occurs in most patients after a median time of 12 to 18 mo...

journal_title：Cancer

authors： Mahler C,Denis L

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:Childhood cancer is a highly curable disease when timely diagnosis and appropriate therapy are provided. A negative impact of the coronavirus disease 2019 (COVID-19) pandemic on access to care for children with cancer is likely but has not been evaluated. METHODS:A 34-item survey focusing on barriers to ped...

journal_title：Cancer

authors： Saab R,Obeid A,Gachi F,Boudiaf H,Sargsyan L,Al-Saad K,Javakhadze T,Mehrvar A,Abbas SS,Abed Al-Agele YS,Al-Haddad S,Al Ani MH,Al-Sweedan S,Al Kofide A,Jastaniah W,Khalifa N,Bechara E,Baassiri M,Noun P,El-Houdzi J,K

更新日期：2020-09-15 00:00:00

abstract：:Acquired myeloperoxidase deficiency has been reported in several hematological malignancies. The clinical course of a patient with acute myelomonocytic leukemia is described which was characterized by staphylococcal infections prior to therapy and again during a period of relapse. Neutropenia was not a feature of thes...

journal_title：Cancer

authors： Kitahara M,Kushner JP

更新日期：1979-12-01 00:00:00