Ferritin-bearing lymphocytes in the diagnosis of breast cancer.

abstract：BACKGROUND:Preclinical and clinical data suggest that both leucovorin (LV) and interferon (IFN) can augment the cytotoxic effects of 5-fluorouracil (5-FU). Based on the rationale of biochemical double modulation, the current Phase II study was undertaken. METHODS:Thirty-two previously untreated patients with advanced ...

journal_title：Cancer

authors： Scheithauer W,Pfeffel F,Kornek G,Marczell A,Wiltschke C,Funovics J

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:Ovarian surface epithelial cells are positionally organized as a single cell layer by a sheet of basement membrane. It is believed that the contact of the ovarian surface epithelial cells with the basement membrane regulates cell growth and ensures the organization of the epithelium. Disabled-2 (Dab2), a sig...

journal_title：Cancer

authors： Capo-Chichi CD,Smith ER,Yang DH,Roland IH,Vanderveer L,Cohen C,Hamilton TC,Godwin AK,Xu XX

更新日期：2002-10-15 00:00:00

abstract：BACKGROUND:Most commercial fecal occult blood tests (FOBT) used for colorectal carcinoma screening of Western populations are guaiac-based, manually developed, subjective, and sensitive to dietary components. Preliminary studies demonstrated the unsuitability of these tests for screening a Chinese population. The goal ...

journal_title：Cancer

authors： Wong WM,Lam SK,Cheung KL,Tong TS,Rozen P,Young GP,Chu KW,Ho J,Law WL,Tung HM,Choi HK,Lee YM,Lai KC,Hu WH,Chan CK,Yuen MF,Wong BC

更新日期：2003-05-15 00:00:00

abstract：:In the past all clear cell carcinomas of the female genital tract were thought to arise from mesonephric remnants. Recently increasing evidence has related their origin to müllerian rather than mesonephric epithelium. One of the main reasons that has been advanced to support their mesonephric origin has been their occ...

journal_title：Cancer

authors： Hasumi K,Ehrmann RL

更新日期：1978-11-01 00:00:00

abstract：BACKGROUND:Childhood cancer survivors are at risk for cardiovascular disease (CVD) because of intensive cancer therapies often accompanied by an unhealthy lifestyle. This study was aimed at 1) describing modifiable CVD risk factors in survivors and 2) investigating the association between different aspects of physical ...

journal_title：Cancer

authors： Schindera C,Zürcher SJ,Jung R,Boehringer S,Balder JW,Rueegg CS,Kriemler S,von der Weid NX

更新日期：2021-01-06 00:00:00

abstract：:Three children with nonlymphoblastic, non-Hodgkin's lymphomas, showed morphologic features that suggested nonlymphoblastic T-cell origin. Tissue for immunologic study was available from two of the three patients; both showed immunophenotypes of T-cells. Although nearly all T-cell lymphomas in children are lymphoblasti...

journal_title：Cancer

authors： Bitter MA,Nachman J,Jones N,Franklin WA,Le Beau MM,Vardiman JW

更新日期：1987-06-15 00:00:00

abstract：BACKGROUND:There is limited published evidence regarding the efficacy of total skin electron beam radiation for patients with the diffuse erythrodermic form of mycosis fungoides. METHODS:Forty-five patients with erythrodermic mycosis fungoides were managed at McMaster University in Hamilton, Ontario, Canada (n=34), an...

journal_title：Cancer

authors： Jones GW,Rosenthal D,Wilson LD

更新日期：1999-05-01 00:00:00

abstract：:Small-cell lung cancer (SCLC) represents 15% to 20% of all lung carcinomas. Approximately 30% to 40% of these cases are diagnosed in patients older than 70 years of age. Staging of SCLC classifies patients as having either limited or extensive-stage disease. The standard treatment for limited-stage disease is platinum...

journal_title：Cancer

authors： Pallis AG,Shepherd FA,Lacombe D,Gridelli C

更新日期：2010-03-01 00:00:00

abstract：:True adenomas of the breast are cellular epithelial lesions, which may be confused with carcinoma and are difficult to classify. We have reviewed 28 adenomas of the breast and have developed specific diagnostic criteria, as well as a classification of breast adenomas based on histologic features. Electron microscopic ...

journal_title：Cancer

authors： Hertel BF,Zaloudek C,Kempson RL

更新日期：1976-06-01 00:00:00

abstract：BACKGROUND:The objective of this study was to estimate the time to treatment failure and survival rate of the three-drug combination of doxorubicin, cisplatin, and ifosfamide as primary and postoperative, adjunctive treatment for teenagers and adults with osteosarcoma (OS). METHODS:Sixty-three eligible patients with n...

journal_title：Cancer

authors： Zalupski MM,Rankin C,Ryan JR,Lucas DR,Muler J,Lanier KS,Budd GT,Biermann JS,Meyers FJ,Antman K

更新日期：2004-02-15 00:00:00

abstract：:Flow cytometry examinations (FCM) were carried out on 110 bladder irrigation specimens from 84 urologic outpatients who had had prior conservative treatment for low stage bladder tumors. The specimens were easily obtained, and adequately cellular in all cases. Of 60 examinations on patients with no cytoscopic abnormal...

journal_title：Cancer

authors： Devonec M,Darzynkiewicz Z,Kostyrka-Claps ML,Collste L,Whitmore WF Jr,Melamed MR

更新日期：1982-01-01 00:00:00

abstract：:High-dose multiagent chemotherapy followed by autologous marrow rescue was used in the treatment of 13 patients with Stage III or IV childhood tumors. Encouraging results are being obtained in abdominal lymphoma (1/3 complete remissions (CR); rhabdomyosarcoma (2/4 CR); and retinoblastoma (1/2 CR). In neuroblastoma, th...

journal_title：Cancer

authors： Ekert H,Ellis WM,Waters KD,Tauro GP

更新日期：1982-02-01 00:00:00

abstract：BACKGROUND:Patients with aggressive non-Hodgkin lymphoma (NHL) require intensive and extensive therapy, which seems impracticable in elderly patients due to hematologic and extrahematologic toxicity. Consequent dose reduction and therapy attenuation can reduce treatment-related toxicity but also decreases therapeutic e...

journal_title：Cancer

authors： Rigacci L,Carpaneto A,Alterini R,Carrai V,Bernardi F,Bellesi G,Longo G,Bosi A,Rossi Ferrini P

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Ovarian tumors of borderline malignancy have a less aggressive behavior and tend to occur at a younger age than their invasive counterparts. The role and extent of fertility-sparing conservative treatments is under continuous evaluation. METHODS:The current study was a retrospective review of 82 patients wi...

journal_title：Cancer

authors： Gotlieb WH,Flikker S,Davidson B,Korach Y,Kopolovic J,Ben-Baruch G

更新日期：1998-01-01 00:00:00

abstract：:Five carcinoid tumors of the thymus were screened immunohistochemically for the occurrence of neuropeptides (ACTH, calcitonin, calcitonin gene-related peptide, cholecystokinin, gastrin, neurotensin, somatostatin, substance P), as well as of serotonin, chromogranin A, and neuron-specific enolase. Most of the patients e...

journal_title：Cancer

authors： Herbst WM,Kummer W,Hofmann W,Otto H,Heym C

更新日期：1987-11-15 00:00:00

abstract：BACKGROUND:In various neoplasms expression of the proliferation-related Ki-67 antigen has successfully been linked with parameters of progression of disease. While a definite grading scheme for oligodendrogliomas has still not been agreed upon, any parameter of tumor proliferation that might be helpful in predicting cl...

journal_title：Cancer

authors： Kros JM,Hop WC,Godschalk JJ,Krishnadath KK

更新日期：1996-09-01 00:00:00

abstract：:This article describes the clinicopathologic features of six cases of uterine papillary serous carcinoma (UPSC), which developed several years after radiation therapy (RT) for cervical carcinoma. The possible etiologic role of radiation is discussed, and the literature on endometrial carcinomas developing after RT is ...

journal_title：Cancer

authors： Parkash V,Carcangiu ML

更新日期：1992-01-15 00:00:00

abstract：:Computed tomography (CT) has emerged from the 1980s to play a dominant role in the pretreatment staging of renal and adrenal carcinomas. For detection, definition (staging), and determination of resectability or recurrence, CT with intravenous contrast enhancement, and more recently, magnetic resonance imaging (MRI) w...

journal_title：Cancer

authors： McClennan BL

更新日期：1991-02-15 00:00:00

abstract：:Until recently the prognosis of childhood non-Hodgkin's lymphoma has been poor. A program of combination chemotherapy and involved area radiotherapy was instituted in the Department of Pediatrics at Roswell Park Memorial Institute in 1971. Thirty-one biopsy proven untreated children entered this study. There were 4 St...

journal_title：Cancer

authors： Brecher ML,Sinks LF,Thomas RR,Freeman AI

更新日期：1978-05-01 00:00:00

abstract：:While investigating the cause of mild polycythemia in a young man, a testicular seminoma was discovered with unusual and tumor-dependent features: an absolute polycythemia with high plasma erythropoietin (EPO) levels, an overproduction of estradiol and testosterone, and a dramatic Leydig cell hyperplasia surrounding t...

journal_title：Cancer

authors： Reman O,Reznik Y,Casadevall N,Lacombe C,Troussard X,Mandard JC,Leporrier M,Mahoudeau J

更新日期：1991-11-15 00:00:00

abstract：:A 30-year-old man underwent orchiectomy in 1962 for a testicular carcinoma composed of choriocarcinomatous and teratocarcinomatous elements. Bilateral pulmonary metastases regressed completely on combination chemotherapy. However, a cerebral metastasis developed in 1963 and caused severe neurologic signs. At craniotom...

journal_title：Cancer

authors： Stolinsky DC

更新日期：1981-03-01 00:00:00

abstract：:Six patients with breast cancer developed pulmonary toxicity following mitomycin therapy. The presenting symptoms were shortness of breath and a dry cough. The radiological pictures varied from a normal chest x-ray to extensive bilateral pneumonitis. The histological findings consisted of diffuse alveolar damage progr...

journal_title：Cancer

authors： Buzdar AU,Legha SS,Luna MA,Tashima CK,Hortobagyi GN,Blumenschein GR

更新日期：1980-01-15 00:00:00

abstract：:Forty-nine patients with regionally confined recurrent malignancy were treated with intra-arterial cis-diamminedichloro platinum II in a Phase I-II trial. A safe starting dose of 120 mg/m2 was established. An overall response rate of 45% was noted with significant responses observed among patients with melanoma, sarco...

journal_title：Cancer

authors： Calvo DB 3rd,Patt YZ,Wallace S,Chuang VP,Benjamin RS,Pritchard JD,Hersh EM,Bodey GP Sr,Mavligit GM

更新日期：1980-03-15 00:00:00

abstract：BACKGROUND:Microsatellite instability occurs frequently in hereditary nonpolyposis colorectal carcinoma, in sporadic gastrointestinal carcinoma, and in other tumors. In these tumors, slippage-related frameshift mutations have been detected at coding mononucleotide repeats in genes such as those for transforming growth ...

journal_title：Cancer

authors： Saeki A,Tamura S,Ito N,Kiso S,Matsuda Y,Yabuuchi I,Kawata S,Matsuzawa Y

更新日期：2000-03-01 00:00:00

abstract：:Two cases of extraskeletal myxoid chondrosarcoma are reported. The patients presented with metastasis to the lung, 10 years and 2 years, respectively, prior to discovery of the primary neoplasms in the soft tissues of the lower extremities. ...

journal_title：Cancer

authors： D'Ambrosio FG,Shiu MH,Brennan MF

更新日期：1986-09-01 00:00:00

abstract：:The unusual genetic disorder epidermolysis bullosa dystrophica has been reported in several patients in whom the chronic cutaneous scars led to the development of cutaneous squamous cell carcinoma. However, only one of these previously reported cases involved the autosomal dominant form of the disease; the remainder o...

journal_title：Cancer

authors： Schwartz RA,Birnkrant AP,Rubenstein DJ,Kim U,Burgess GH,Stoll HL Jr,Chai SW,Southwick GJ,Milgrom H

更新日期：1981-02-01 00:00:00

abstract：BACKGROUND:The goal of this study was to compare health-related quality of life (HRQL) from diagnosis to 10 years postdiagnosis among breast cancer survivors (BCS) and women without cancer over the same period and to identify BCS subgroups exhibiting different HRQL trajectories. METHODS:Our analysis included 141 BCS a...

journal_title：Cancer

authors： Avis NE,Levine B,Goyal N,Crawford SL,Hess R,Colvin A,Bromberger JT,Greendale GA

更新日期：2020-05-15 00:00:00

abstract：:Currently, there is a "divide" between cancer survivorship initiatives and minority participation. The level of participation is nearly nonexistent in many cancer support and control initiatives. Cancer survivorship resources that facilitate access to treatment, psychosocial interventions, clinical trials, and researc...

journal_title：Cancer

authors： Guidry JJ,Torrence W,Herbelin S

更新日期：2005-12-01 00:00:00

abstract：:Between 1957 and February 1981, 782 patients received cytotoxic chemotherapy for gestational trophoblastic tumors (GTT) in the Department of Medical Oncology, Charing Cross Hospital (London, England). Sixty-nine (8.8%) patients had central nervous system (CNS) metastases. Thirty-three of them (48%) presented with CNS ...

journal_title：Cancer

authors： Athanassiou A,Begent RH,Newlands ES,Parker D,Rustin GJ,Bagshawe KD

更新日期：1983-11-01 00:00:00

abstract：:The authors retrospectively searched for human papillomavirus (HPV) types 16 and 18 in 60 cases of carcinoma arising from the nasal cavities (NC) and paranasal sinuses (PS) by using the polymerase chain reaction (PCR) on DNA extracted from formalin-fixed, paraffin-embedded tissues. In cases of SCC (n = 49), the author...

journal_title：Cancer

authors： Furuta Y,Takasu T,Asai T,Shinohara T,Sawa H,Nagashima K,Inuyama Y

更新日期：1992-01-15 00:00:00