Squamous cell carcinoma in dominant type epidermolysis bullosa dystrophica.

abstract：BACKGROUND:The antiviral, proapoptotic, antiproliferative gene 2'-5' oligoadenylate synthetase (2-5OAS1) converts adenosine triphosphate into a series of 2'-5' oligoadenylates (2-5A). In turn, 2-5A activates latent ribonuclease (RNaseL), a candidate hereditary prostate cancer gene. OAS1 polymorphism (reference single n...

journal_title：Cancer

authors： Mandal S,Abebe F,Chaudhary J

更新日期：2011-12-15 00:00:00

abstract：BACKGROUND:It is important for clinicians, researchers, and others who shape public health policy to understand the demographic correlates and psychologic factors that drive health behaviors, such as screening for early detection of cancer, particularly among individuals at high risk for developing the disease. METHOD...

journal_title：Cancer

authors： Beebe-Dimmer JL,Wood DP Jr,Gruber SB,Chilson DM,Zuhlke KA,Claeys GB,Cooney KA

更新日期：2004-04-01 00:00:00

abstract：:Quality assurance for the management of multicenter clinical trials requires timely patient and data accrual and consistency with design parameters. Data from central pathology review, treatment modality, and follow-up as well as trial end points direct the selection of appropriate compliance measures. To integrate th...

journal_title：Cancer

authors： Pollock BH

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to confirm whether black and white women with endometrial cancer are equally tolerant of chemotherapy and identify factors that impact survival. METHODS:A retrospective review of 169 black women and 982 white women with the International Federation of Gynecologists and Obstetri...

journal_title：Cancer

authors： Farley JH,Tian C,Rose GS,Brown CL,Birrer M,Risinger JI,Thigpen JT,Fleming GF,Gallion HH,Maxwell GL

更新日期：2010-01-15 00:00:00

abstract：:Hodgkin's disease (HD) was diagnosed in 24 patients who were either seropositive for human immunodeficiency virus (HIV) (21) or members of a high-risk group (three), but had not developed acquired immune deficiency syndrome (AIDS). Clinical presentation of the disease was characterized by constitutional symptoms in al...

journal_title：Cancer

authors： Ree HJ,Strauchen JA,Khan AA,Gold JE,Crowley JP,Kahn H,Zalusky R

更新日期：1991-03-15 00:00:00

abstract：BACKGROUND:Programmed death 1 (PD-1) signaling in the tumor microenvironment dampens immune responses to cancer, and blocking this axis induces antitumor effects in several malignancies. Clinical studies of PD-1 blockade are only now being initiated in pediatric patients, and little is known regarding programmed death-...

journal_title：Cancer

authors： Majzner RG,Simon JS,Grosso JF,Martinez D,Pawel BR,Santi M,Merchant MS,Geoerger B,Hezam I,Marty V,Vielh P,Daugaard M,Sorensen PH,Mackall CL,Maris JM

更新日期：2017-10-01 00:00:00

abstract：:Chemotherapy once relegated to end stage patients has markedly improved with the use of combinations. Response rates with single agents have improved from 15 to 35%, to 50 to 70%, using combinations with an increase in complete response rates to about 25%. A series of four studies completed by the Eastern Cooperative ...

journal_title：Cancer

authors： Carbone PP,Bauer M,Band P,Tormey D

更新日期：1977-06-01 00:00:00

abstract：:During 1982 and 1983, 4496 new cases were recorded in the French Registry of acute leukemia and myelodysplastic syndromes by the French Group of Hematologic Morphology. This cooperative group associated members of 37 university centers spread throughout France; these centers handle the overwhelming majority of acute l...

journal_title：Cancer

authors：

更新日期：1987-09-15 00:00:00

abstract：METHODS:Between 1983 and 1989, 42 patients with Stage II, III, and IV, node-negative, squamous cell head and neck cancer were treated with concurrent 5-fluorouracil, cisplatin, and radiation therapy. Two courses of chemotherapy with 30 Gy of concurrent radiation therapy were to be followed in all patients by definitive...

journal_title：Cancer

authors： Adelstein DJ,Sharan VM,Damm C,Earle AS,Shah AC,Haria CD,Trey JE,Carter SG,Hines JD

更新日期：1992-12-01 00:00:00

abstract：METHODS:The prognostic significance of flow cytometric analysis in patients with node-negative invasive breast carcinoma was evaluated in a retrospective series of 158 patients with a minimum follow-up study of 9 years. RESULTS:The ploidy status could be assessed in 147 specimens (93%), and the proliferative phase or ...

journal_title：Cancer

authors： Bosari S,Lee AK,Tahan SR,Figoni MA,Wiley BD,Heatley GJ,Silverman ML

更新日期：1992-10-01 00:00:00

abstract：:A clinicopathologic study of 51 patients with endoscopically removed large bowel polyps showing histologic evidence of malignancy, either focally, to a massive extent, or comprising the entire polyp, revealed only one absolute finding capable of predicting residual disease, namely, the presence of cancer at the resect...

journal_title：Cancer

authors： Lipper S,Kahn LB,Ackerman LV

更新日期：1983-11-01 00:00:00

abstract：BACKGROUND:In addition to tumor thickness, several other prognostic parameters have been identified in primary human melanomas. Some are available readily (localization, gender, age, and ulceration). Others must be evaluated with a moderate or even substantial amount of work (mitoses and immunohistochemical markers). T...

journal_title：Cancer

authors： Ostmeier H,Fuchs B,Otto F,Mawick R,Lippold A,Krieg V,Suter L

更新日期：1999-06-01 00:00:00

abstract：:Nine human hybridoma cell lines were established from a fusion of axillary lymph node lymphocytes of a patient with breast ductal carcinoma with a human lymphoblastoid cell line. The human hybridoma nature of the fusion products was confirmed by chromosomal analysis and HLA typing. The hybridomas are stable over a yea...

journal_title：Cancer

authors： Shoenfeld Y,Hizi A,Tal R,Smorodinsky NI,Lavie G,Mor C,Schteren S,Mammon Z,Pinkhas J,Keydar T

更新日期：1987-01-01 00:00:00

abstract：:Extremely high concentrations of human chorionic gonadotropin in the cerebrospinal fluid were found in a 5-year-old boy presenting sexual precocity and leg pain. An intramedullary spinal cord tumor was revealed by myelogram and metrizamide computerized tomography, and a biopsy specimen taken at laminectomy. Histologic...

journal_title：Cancer

authors： Hisa S,Morinaga S,Kobayashi Y,Ojima M,Chikaoka H,Sasano N

更新日期：1985-06-15 00:00:00

abstract：:A case of transfusion-induced graft-versus-host disease (GVHD) occurring in a 31-year-old female with Hodgkin's disease in complete remission is reported. Clinical features are similar to 19 other reported cases of transfusion-induced GVHD associated with malignant lymphoma. The lack of relationship with underlying hi...

journal_title：Cancer

authors： Spitzer TR,Cahill R,Cottler-Fox M,Treat J,Sacher R,Deeg HJ

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND:Prostate carcinoma metastasizes frequently to the skeleton, causing significant morbidity, particularly severe bone pain. Metastatic lesions typically are osteosclerotic, but there is experimental, histologic, and biochemical evidence of increased bone resorption. Furthermore, bone resorption rates appear to...

journal_title：Cancer

authors： Papapoulos SE,Hamdy NA,van der Pluijm G

更新日期：2000-06-15 00:00:00

abstract：:The urinary neopterin excretion was measured by high-performance liquid chromatography in 417 healthy subjects and in 76 patients with clinically and pathohistologically verified neoplasias of the urinary tract (bladder tumor, carcinoma of the prostate, and renal cell carcinoma). The patients with early tumor stages b...

journal_title：Cancer

authors： Aulitzky W,Frick J,Fuchs D,Hausen A,Reibnegger G,Wachter H

更新日期：1985-03-01 00:00:00

abstract：:Oral submucous fibrosis (OSF) is a chronic disease of the oral mucosa characterized by inflammation and a progressive fibrosis of the lamina propria and deeper connective tissues. It is a condition predominantly seen among people of Indian origin, and an epidemiologic survey done a decade ago showed no less than 250,0...

journal_title：Cancer

authors： Pillai R,Balaram P,Reddiar KS

更新日期：1992-04-15 00:00:00

abstract：:Recombinant human granulocyte colony-stimulating factor (rhG-CSF) was administered intraperitoneally in combination with multidrug chemotherapy using methotrexate (M), vinblastine (V), doxorubicin (A), and cisplatin (C, or for the combination, MVAC) to C3H/He mice (5-week-old females) after experimental carcinoma, MBT...

journal_title：Cancer

authors： Akaza H,Fukushima H,Koiso K,Aso Y

更新日期：1992-02-15 00:00:00

abstract：:Chemokines are chemoattractant cytokines that regulate the trafficking and activation of leukocytes and other cell types under a variety of inflammatory and noninflammatory conditions. Over the past few years, studies have increasingly shown that chemokines play an important role in several aspects of tumor progressio...

journal_title：Cancer

authors： Ruffini PA,Morandi P,Cabioglu N,Altundag K,Cristofanilli M

更新日期：2007-06-15 00:00:00

abstract：BACKGROUND:Lysosomal proteases are implicated in cancer progression and metastasis. In the current study, using subtraction cloning for genes that are differentially expressed in metastasis, the authors isolated a clone encoding ceroid lipofuscinosis, neuronal 2 (CLN2), which is a lysosomal serine protease defective in...

journal_title：Cancer

authors： Tsukamoto T,Iida J,Dobashi Y,Furukawa T,Konishi F

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:The goal of the current study was to assess the toxicity, safety, and efficacy of pentostatin in patients with T-cell lymphoid malignancies. METHODS:Patients were eligible if they had biopsy-proven T-cell lymphoma or leukemia and failure to respond to previous therapy or an expected complete response rate t...

journal_title：Cancer

authors： Tsimberidou AM,Giles F,Duvic M,Fayad L,Kurzrock R

更新日期：2004-01-15 00:00:00

abstract：:The current classification of cutaneous malignant lymphomas (ML) into low-grade and high-grade lymphomas was found to be of limited reproducibility and permitted only a rough prediction about outcome. With this in mind, the relationship between nuclear DNA content and both prognosis and histologic grading according to...

journal_title：Cancer

authors： Vogt T,Stolz W,Braun-Falco O,Kaudewitz P,Eckert F,Abmayr W,Dummer R,Burg G

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND:Heparanase up-regulation has been correlated with reduced postoperative survival in various cancers. METHODS:Heparanase expression was analyzed in 60 consenting tongue (mobile) cancer patients by means of immunohistochemistry. Heparanase levels were also analyzed in the saliva of both healthy controls and t...

journal_title：Cancer

authors： Nagler R,Ben-Izhak O,Cohen-Kaplan V,Shafat I,Vlodavsky I,Akrish S,Ilan N

更新日期：2007-12-15 00:00:00

abstract：:Clinical, histological and ultrastructural features of three small cell carcinomas arising in the parotid gland are presented. The light microscopic appearance of two of the neoplasms suggested neuroendocrine cell derivation, confirmed by electron microscopy in both instances. The fine structure of the third neoplasm ...

journal_title：Cancer

authors： Kraemer BB,Mackay B,Batsakis JG

更新日期：1983-12-01 00:00:00

abstract：:An infant who presented with a thigh mass and coagulopathy was found to have a hemangioendothelioma. The tumor rapidly enlarged despite accepted therapeutic modalities, and the child died after a sudden cardiac arrest. Postmortem examination revealed a highly invasive tumor mass that had infiltrated the bowel and invo...

journal_title：Cancer

authors： Weinblatt ME,Kahn E,Kochen JA

更新日期：1984-11-15 00:00:00

abstract：:A study of primary epithelial neoplasms of the appendix (with the exception of classical carcinoids), produced 24 adenocarcinomas and 42 benign lesions from the files of the Laboratory of Surgical Pathology of Columbia University. Invasive adenoarcinomas were often complicated by appendicitis and were then unexpectedl...

journal_title：Cancer

authors： Wolff M,Ahmed N

更新日期：1976-05-01 00:00:00

abstract：BACKGROUND:Fluorescence in situ hybridization (FISH) and immunohistochemistry (IHC) tests are commonly used to assess human epidermal growth factor 2 (HER2) status of tumors in patients with breast cancer. This analysis evaluates the likely cost-effectiveness of expanded retesting to assess HER2 tumor status in women w...

journal_title：Cancer

authors： Garrison LP Jr,Lalla D,Brammer M,Babigumira JB,Wang B,Perez EA

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Local recurrence is the most frequent site of failure after resection for pancreatic cancer. Tolerance, local control, and survival obtained by the association of resection and intraoperative radiation therapy (IORT) were reported. METHODS:Between June 1985 and March 1993, 90 resections for pancreatic cance...

journal_title：Cancer

authors： Zerbi A,Fossati V,Parolini D,Carlucci M,Balzano G,Bordogna G,Staudacher C,Di Carlo V

更新日期：1994-06-15 00:00:00

abstract：:To surgery, radiation, and chemotherapy for cancer has been added a fourth modality: multidisciplinary therapy, which is improving the survival and cure rate among children. Specialists working together in a coordinated effort suspect, confirm, then treat cancer; follow and rehabilitate the patient; analyze and report...

journal_title：Cancer

authors： Murphy ML

更新日期：1975-03-01 00:00:00