Intramedullary spinal cord germinoma producing HCG and precocious puberty in a boy.

Abstract:

:Extremely high concentrations of human chorionic gonadotropin in the cerebrospinal fluid were found in a 5-year-old boy presenting sexual precocity and leg pain. An intramedullary spinal cord tumor was revealed by myelogram and metrizamide computerized tomography, and a biopsy specimen taken at laminectomy. Histologically, the tumor showed germinoma with syncytiotrophoblastic giant cells. The tumor remitted for 5 months after irradiation of 3500 rad and chemotherapy, but recurred in spite of adding 7500 rad and more aggressive chemotherapy. No relapse has been seen for 1 year after amputation of the spinal cord at the T7 level.

journal_name

Cancer

journal_title

Cancer

authors

Hisa S,Morinaga S,Kobayashi Y,Ojima M,Chikaoka H,Sasano N

doi

10.1002/1097-0142(19850615)55:12<2845::aid-cncr282

subject

Has Abstract

pub_date

1985-06-15 00:00:00

pages

2845-9

issue

12

eissn

0008-543X

issn

1097-0142

journal_volume

55

pub_type

杂志文章

相关文献

CANCER文献大全
  • Prognostic significance of DNA cytometry in cutaneous malignant lymphomas.

    abstract::The current classification of cutaneous malignant lymphomas (ML) into low-grade and high-grade lymphomas was found to be of limited reproducibility and permitted only a rough prediction about outcome. With this in mind, the relationship between nuclear DNA content and both prognosis and histologic grading according to...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19910901)68:5<1095::aid-cncr2820

    authors: Vogt T,Stolz W,Braun-Falco O,Kaudewitz P,Eckert F,Abmayr W,Dummer R,Burg G

    更新日期:1991-09-01 00:00:00

  • Indomethacin sensitive suppressor-cell activity in head and neck cancer patients. The role of the adherent mononuclear cell.

    abstract::Head and neck cancer (H&N CA) patients have known depression of cell-mediated immunity. There is suggestive evidence that prostaglandin (PGE2)-secreting cells may be a major factor. The authors have sought to determine the role of PGE2-releasing monocytes-macrophages in this immune depression by determining the effect...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19880201)61:3<462::aid-cncr28206

    authors: Wanebo HJ,Riley T,Katz D,Pace RC,Johns ME,Cantrell RW

    更新日期:1988-02-01 00:00:00

  • Lactase dehydrogenase as a tumor marker for recurrent disease in Ewing's sarcoma.

    abstract::The serum lactase dehydrogenase (LDH) of 56 patients with Ewing's sarcoma was examined to determine the use of LDH as a tumor marker. The initial LDH level was used to determine its ability to predict survival. The follow-up LDH level also was examined, as an indicator of recurrent disease. The initial LDH level was f...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19870401)59:7<1245::aid-cncr2820

    authors: Farley FA,Healey JH,Caparros-Sison B,Godbold J,Lane JM,Glasser DB

    更新日期:1987-04-01 00:00:00

  • Isolation perfusion with cisplatin for malignant melanoma of the limbs.

    abstract::The role of hyperthermic isolation perfusion in the treatment of advanced melanoma of the limbs is clearly important. However, attention has in the past been focussed mainly on surgical aspects of the procedure. Whereas, equivalent interest in chemotherapy considerations has been lacking. A group of 15 patients have b...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19870315)59:6<1068::aid-cncr2820

    authors: Klein ES,Ben-Ari GY

    更新日期:1987-03-15 00:00:00

  • Improved survival in women with BRCA-associated ovarian carcinoma.

    abstract:BACKGROUND:The objective of this study was to determine the clinical characteristics, treatment response, and frequency of p53 overexpression in Ashkenazi Jewish women with hereditary ovarian carcinoma. METHODS:Seventy-one Jewish women with epithelial ovarian carcinoma (EOC) were tested for the three BRCA founder muta...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.11310

    authors: Cass I,Baldwin RL,Varkey T,Moslehi R,Narod SA,Karlan BY

    更新日期:2003-05-01 00:00:00

  • Specific expression of the ras-related rab3A gene in human normal and malignant neuroendocrine cells.

    abstract:BACKGROUND:The authors originally demonstrated the tissue-specific expression of the rab3A gene in the mouse brain. In the current study, they analyze the activity of this gene in fresh human tumors associated with neuronal phenotype compared with normal and malignant cells from other origins. METHODS:The authors stud...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19921115)70:10<2552::aid-cncr282

    authors: Culine S,Rousseau-Merck MF,Honoré N,Nezelof C,Olofsson B

    更新日期:1992-11-15 00:00:00

  • Analysis of ThinPrep cytology in establishing the diagnosis of small cell carcinoma of lung.

    abstract:BACKGROUND:ThinPrep liquid-based cytology (TP) preparations are being used increasingly in nongynecologic specimens. To the authors' knowledge, few studies to date have evaluated TP cytology in the setting of small cell carcinoma of the lung (SCCL). Accurately differentiating SCCL from other lung tumors has important c...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncy.20007

    authors: Kim S,Owens CL

    更新日期:2009-02-25 00:00:00

  • Randomized, placebo-controlled trial of Saforis for prevention and treatment of oral mucositis in breast cancer patients receiving anthracycline-based chemotherapy.

    abstract:BACKGROUND:Oral mucositis (OM) is a frequent complication of mucotoxic cancer therapy, causing significant oral pain, increased infection risk, and impaired functioning. The efficacy and safety of Saforis (glutamine) powder in UpTec for oral suspension was evaluated for the prevention and treatment of OM. METHODS:Thre...

    journal_title:Cancer

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1002/cncr.22384

    authors: Peterson DE,Jones JB,Petit RG 2nd

    更新日期:2007-01-15 00:00:00

  • Public attitudes toward cancer pain.

    abstract::This study examined public attitudes toward pain associated with cancer and its treatment. A variety of issues were assessed, including the extent to which pain is associated with cancer, fear of pain as a factor in the decision to delay seeking treatment, and concerns about the use of narcotic analgesics for pain con...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19851101)56:9<2337::aid-cncr2820

    authors: Levin DN,Cleeland CS,Dar R

    更新日期:1985-11-01 00:00:00

  • Concanavalin A-binding histiocytes in Hodgkin's disease. A predictor of early relapse.

    abstract::Staining with Concanavalin agglutinin (Con A) reveals a far greater number of macrophage-histiocytes (M-H) in paraffin sections than any other staining method. With Con A staining, the shapes of stromal M-H are clearly visualized, thus enabling a study of their morphologic variations. Con A staining patterns were also...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19860701)58:1<87::aid-cncr282058

    authors: Ree HJ

    更新日期:1986-07-01 00:00:00

  • Patterns and risk factors associated with aromatase inhibitor-related arthralgia among breast cancer survivors.

    abstract:BACKGROUND:Arthralgia is common in postmenopausal breast cancer survivors (BCS) who are receiving aromatase inhibitors (AIs). The objective of this study was to evaluate the perceived onset, characteristics, and risk factors for AI-related arthralgia (AIA). METHODS:In a cross-sectional survey of postmenopausal BCS who...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.24419

    authors: Mao JJ,Stricker C,Bruner D,Xie S,Bowman MA,Farrar JT,Greene BT,DeMichele A

    更新日期:2009-08-15 00:00:00

  • Intrahepatic mitomycin C as a salvage treatment for patients with hepatic metastases from colorectal carcinoma.

    abstract::Sixty-four evaluable patients with hepatic metastases from colorectal carcinoma, who did not have evidence of extrahepatic disease, were treated with intrahepatic (IH) mitomycin C (M) after disease progression or intolerance to treatment with IH fluorodeoxyuridine (FUDR). Eleven patients (17%) had a partial response (...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19891201)64:11<2203::aid-cncr282

    authors: Schneider A,Kemeny N,Chapman D,Niedzwiecki D,Oderman P

    更新日期:1989-12-01 00:00:00

  • Multiple early gastric carcinomas. Clinicopathologic features and histogenesis.

    abstract:BACKGROUND:Multiple early gastric carcinomas were found in 5-15% of patients with early gastric carcinoma. The goals of this study were to clarify the clinicopathologic features of multiple early gastric carcinomas and to investigate their histogenesis. METHODS:Of 724 patients with early gastric carcinoma, there were ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:

    authors: Isozaki H,Okajima K,Hu X,Fujii K,Sako S

    更新日期:1996-11-15 00:00:00

  • Impact of lung cancer screening results on participant health-related quality of life and state anxiety in the National Lung Screening Trial.

    abstract:BACKGROUND:Low-dose computed tomography (LDCT) lung screening has been associated with a 20% reduction in lung cancer mortality. A major barrier to the adoption of lung screening is the potential negative psychological impact of a false-positive (FP) screen, occurring in 20% to 50% of those screened. The objective of t...

    journal_title:Cancer

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1002/cncr.28833

    authors: Gareen IF,Duan F,Greco EM,Snyder BS,Boiselle PM,Park ER,Fryback D,Gatsonis C

    更新日期:2014-11-01 00:00:00

  • Risk factors for bilateral testicular germ cell tumors. Does heredity play a role?

    abstract::Twenty-three bilateral testicular germ cell tumors (four synchronous and 19 sequential tumors) were investigated for potential risk factors. The incidence of maldescensus testis was not found to be higher than in patients with unilateral disease. The histologic findings of the first tumor did not have any effect on th...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/1097-0142(19910815)68:4<916::aid-cncr28206

    authors: Kratzik C,Aiginger P,Kuber W,Riccabona M,Kührer I,Joos H,Frick J,Amann G,Mayr W

    更新日期:1991-08-15 00:00:00

  • Distinct cytogenetic and clinicopathologic features in acute myeloid leukemia after occupational exposure to pesticides and organic solvents.

    abstract:BACKGROUND:To study the correlation of environmental exposure to potentially mutagenic agents and the clinicopathologic picture in acute myeloid leukemia (AML), clinical features, morphologic characteristics, immunophenotype, and cytogenetics were studied in 59 patients with newly diagnosed AML. METHODS:Based on inter...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19920701)70:1<77::aid-cncr282070

    authors: Fagioli F,Cuneo A,Piva N,Carli MG,Previati R,Balboni M,Tomasi P,Cariani D,Scapoli G,Castoldi G

    更新日期:1992-07-01 00:00:00

  • Adenoid cystic carcinoma of the salivary gland. Sustained complete response to chemotherapy.

    abstract::A patient developed widely metastatic adenoid cystic carcinoma of the parotid gland after several local recurrences. A complete regression of pleural, pulmonary parenchymal, cutaneous, and bone metastases was seen following therapy with 5-fluorouracil, Adriamycin, and mitomycin C. This is the second complete response ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19830215)51:4<589::aid-cncr28205

    authors: Budd GT,Groppe CW

    更新日期:1983-02-15 00:00:00

  • Separate primary carcinomas of the esophagus and head and neck region in the same patient.

    abstract::From 1949 to 1972 at Memorial Sloan-Kettering Cancer Center, 60 patients with primary cancers of both the oral cavity, pharynx, larynx (OPL) and esophagus were studied. In 15, the cancers occurred synchronously, and in 68% they occurred within 2 years of each other, the longest interval being 27 years. The tongue and ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197601)37:1<85::aid-cncr28203701

    authors: Cahan WG,Castro EB,Rosen PP,Strong EW

    更新日期:1976-01-01 00:00:00

  • How well do medical oncologists' perceptions reflect their patients' reported physical and psychosocial problems? Data from a survey of five oncologists.

    abstract:BACKGROUND:Modern cancer treatments can cure or prolong patients' lives. However, the associated physical and psychosocial problems can detrimentally affect patients' compliance with treatment and, ultimately, their outcomes. Therefore, oncologists need to recognize the problems experienced by their patients and, when ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:

    authors: Newell S,Sanson-Fisher RW,Girgis A,Bonaventura A

    更新日期:1998-10-15 00:00:00

  • Prognostically favorable immunogens of human breast cancer tissue: antigenic similarity to murine mammary tumor virus.

    abstract::A leukocyte migration procedure was utilized to test cellular hypersensitivity of breast cancer patients' leukocytes to autologous and homologous breast cancer tissues and to murine milk containing murine mammary tumor virus (MuMTV). The in vitro responsiveness of the leukocytes and the antigenicity of breast cancer t...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197501)35:1<121::aid-cncr2820350

    authors: Black MM,Zachrau RE,Shore B,Moore DH,Leis HP Jr

    更新日期:1975-01-01 00:00:00

  • The use of oncofetal ferritin-bearing lymphocytes as a marker for the screening, diagnosis, and follow-up of patients with early breast malignancy screening of 3400 women.

    abstract::The potential of using a blood test enumerating oncofetal ferritin-bearing lymphocytes (FBL) as a biomarker for early breast cancer was further explored. Nine hundred women attending a high-risk breast cancer clinic and 2500 normal-risk women were physically examined and their blood drawn for FBL determination using a...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19890801)64:3<691::aid-cncr28206

    authors: Moroz C,Kahn M,Ron E,Luria H,Chaimoff C

    更新日期:1989-08-01 00:00:00

  • A morphometric study of neovascularization in colorectal carcinoma.

    abstract:BACKGROUND:Neovascularization reportedly is correlated with metastasis, recurrence, and prognosis in some types of tumors. Microvessel quantification in so-called "hot spots" has been studied extensively as the only factor reflecting angiogenesis in various malignant tumors. The objective of this report was to evaluate...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:

    authors: Pavlopoulos PM,Konstantinidou AE,Agapitos E,Kavantzas N,Nikolopoulou P,Davaris P

    更新日期:1998-11-15 00:00:00

  • The influence of histologic type on survival in non-Hodgkin's lymphoma.

    abstract::Histologic groups in 231 cases of malignant lymphoma were correlated with survival data at 100 months from the time of initiation of the study. Patients in the first two decades of life fared comparably with adults, but those over 60 years of age showed a poorer survival trend. Seven favorable and four unfavorable his...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19810615)47:12<2894::aid-cncr282

    authors: Barcos M,Herrmann R,Pickren JW,Naeher C,Han T,Stutzman L,Henderson ES

    更新日期:1981-06-15 00:00:00

  • Benign breast lesions at risk of developing cancer--a challenging problem in breast cancer screening programs: five years' experience of the Breast Cancer Screening Program in Verona (1999-2004).

    abstract:BACKGROUND:Cytology and core-needle biopsies are not always sufficient to exclude malignancy in benign breast lesions (BBL) that are at risk of developing cancer, and open biopsy often is mandatory. In screening programs, open biopsies performed for lesions that are at risk of developing malignancy are considered benig...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.24038

    authors: Manfrin E,Mariotto R,Remo A,Reghellin D,Falsirollo F,Dalfior D,Bricolo P,Piazzola E,Bonetti F

    更新日期:2009-02-01 00:00:00

  • Estradiol and testosterone levels in the peripheral and ovarian circulations in patients with endometrial cancer.

    abstract::Estradiol and testosterone levels in the peripheral and ovarian circulation of patients with endometrial cancer and of postmenopausal women were studied. These levels proved to be the same in the two groups. The ovaries of neither group secreted estradiol. The testosterone level in the ovarian circulation of all exami...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197911)44:5<1809::aid-cncr282044

    authors: Schenker JG,Weinstein D,Okon E

    更新日期:1979-11-01 00:00:00

  • Primary chemotherapy for newly diagnosed nonsmall cell lung cancer patients with synchronous brain metastases compared with whole-brain radiotherapy administered first : result of a randomized pilot study.

    abstract:BACKGROUND:This randomized pilot trial investigated whether primary chemotherapy was feasible in terms of efficacy, survival, toxicity profile, and quality of life compared with whole-brain radiotherapy (WBRT) given first in chemotherapy-naive patients nonsmall cell lung cancer (NSCLC) with synchronous brain metastasis...

    journal_title:Cancer

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/cncr.23526

    authors: Lee DH,Han JY,Kim HT,Yoon SJ,Pyo HR,Cho KH,Shin SH,Yoo H,Lee SH,Lee JS

    更新日期:2008-07-01 00:00:00

  • Glandular cardiac myxomas. Histologic, immunohistochemical, and ultrastructural evidence of epithelial differentiation.

    abstract::Histologic, histochemical, immunocytochemical, and ultrastructural features of two cardiac myxomas containing glandular elements are reported. Glandular elements in both cases stained positively with both mucicarmine and periodic acid-Schiff reagent with diastase pretreatment (DPAS). Immunoperoxidase studies demonstra...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19870515)59:10<1767::aid-cncr282

    authors: Goldman BI,Frydman C,Harpaz N,Ryan SF,Loiterman D

    更新日期:1987-05-15 00:00:00

  • Prolactin cell carcinoma of the pituitary. Clinicopathologic, immunohistochemical, and ultrastructural study of a case with cranial and extracranial metastases.

    abstract::A patient with a primary adenohypophyseal neoplasm who had a long course marked by multiple surgical resections, radiation therapy, and high-dose dopamine agonist therapy developed local invasion as well as cranial and extracranial osseous metastatic lesions. The serum prolactin levels were greatly elevated, and immun...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19850201)55:3<598::aid-cncr28205

    authors: Scheithauer BW,Randall RV,Laws ER Jr,Kovacs KT,Horvath E,Whitaker MD

    更新日期:1985-02-01 00:00:00

  • Multiple visceral and cutaneous granular cell tumors. Ultrastructural and immunocytochemical evidence of Schwann cell origin.

    abstract::Granular cell tumor of the stomach is rare and may occur in association with similar tumors in the skin. Two such tumors were found in association with cutaneous granular cell tumors in two black females. Infiltrating carcinoma of the stomach was suspected at surgery in one case. All of the lesions were typical granul...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19840515)53:10<2104::aid-cncr282

    authors: Seo IS,Azzarelli B,Warner TF,Goheen MP,Senteney GE

    更新日期:1984-05-15 00:00:00

  • Prognostic significance of cytomorphology in the cutaneous T-cell lymphomas.

    abstract::In this retrospective study, the degree of differentiation of atypical lymphoid cells was assessed in pretreatment cutaneous biopsy specimens from 248 patients with cutaneous T-cell lymphomas (mycosis fungoides and Sézary syndrome) and the findings were correlated with the subsequent therapeutic results. Overall, pati...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19810101)47:1<119::aid-cncr28204

    authors: Vonderheid EC,Tam DW,Johnson WC,Van Scott EJ,Wallner PE

    更新日期:1981-01-01 00:00:00