A morphometric study of neovascularization in colorectal carcinoma.

abstract：BACKGROUND:The use of docetaxel prolongs survival for patients with castrate-resistant prostate cancer (CRPC). Inhibition of vascular endothelial growth factor (VEGF) with bevacizumab may further enhance the antitumor effect of docetaxel and estramustine in patients with CRPC. METHODS:This cooperative group trial enro...

journal_title：Cancer

authors： Picus J,Halabi S,Kelly WK,Vogelzang NJ,Whang YE,Kaplan EB,Stadler WM,Small EJ,Cancer and Leukemia Group B.

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Because of the small number of cases (five) reported between 1929 and 1969 and a significant increase reported in the decade of the 1970s, the Familial Ovarian Cancer Registry was established in 1981 to study the occurrence of familial ovarian cancer in the United States. METHODS:Any woman (with or without ...

journal_title：Cancer

authors： Piver MS,Baker TR,Jishi MF,Sandecki AM,Tsukada Y,Natarajan N,Mettlin CJ,Blake CA

更新日期：1993-01-15 00:00:00

abstract：:Over a 7 year period, 85 cancer patients were managed by the nutrition service of St. Joseph's Hospital, Toronto. All these patients were nutritionally depleted, had obstruction to the gastrointestinal tract, or had postoperative complications such as enterocutaneous fistulas, evisceration or intraabdominal sepsis, wh...

journal_title：Cancer

authors： Deitel M,Vasic V,Alexander MA

更新日期：1978-06-01 00:00:00

abstract：BACKGROUND:The benefits of an active lifestyle after a breast cancer diagnosis are well recognized, but the majority of survivors are insufficiently active. The ACTIVATE Trial examined the efficacy of an intervention (use of the Garmin Vivofit 2 activity monitor coupled with a behavioral feedback and goal-setting sessi...

journal_title：Cancer

authors： Lynch BM,Nguyen NH,Moore MM,Reeves MM,Rosenberg DE,Boyle T,Vallance JK,Milton S,Friedenreich CM,English DR

更新日期：2019-08-15 00:00:00

abstract：:The autopsies of 80 patients with Hodgkin's disease (HD) were reviewed. Nearly one-third of the patients died without evidence of HD at autopsy. Four patients died with clinically unsuspected HD. Infection was the most common cause of death but a significant number of patients died of complications of therapy, both be...

journal_title：Cancer

authors： Colby TV,Hoppe RT,Warnke RA

更新日期：1981-04-01 00:00:00

abstract：BACKGROUND:Multiple lymphomatous polyposis (MLP) results from gastrointestinal involvement by a B-cell lymphoma that originates from the mantle zone of lymphoid follicles. This well described clinicopathologic entity has a poor prognosis: the rate of complete response after conventional chemotherapy is very low. High d...

journal_title：Cancer

authors： Mahé B,Moreau A,Moreau P,Le Tortorec S,Harousseau JL,Milpied N

更新日期：1995-06-01 00:00:00

abstract：:Breast cancer specimens from 600 women were assayed for estrogen receptors (ER) using an immunocytochemical assay (ICA) employing the monoclonal antiestrophilin antibody H222 Sp gamma. Results showed significant correlation with biochemical ER determinations as well as with tumor grade and menopausal status. In 449 ca...

journal_title：Cancer

authors： Pertschuk LP,Kim DS,Nayer K,Feldman JG,Eisenberg KB,Carter AC,Rong ZT,Thelmo WL,Fleisher J,Greene GL

更新日期：1990-10-15 00:00:00

abstract：BACKGROUND:Vascular endothelial growth factor-C (VEGF-C) plays an important role in lymphangiogenesis and activates VEGF receptor-3 (VEGFR-3). Lymphatic spread is an important prognostic factor in patients with lung adenocarcinoma. The aim of the current study was to determine whether the expression of VEGF-C and VEGFR...

journal_title：Cancer

authors： Kojima H,Shijubo N,Yamada G,Ichimiya S,Abe S,Satoh M,Sato N

更新日期：2005-10-15 00:00:00

abstract：:An unusually high association of other primary cancers (9.7%) was found during the analysis of 403 consecutive cases of carcinoma of the lung diagnosed at DGMC between 1960 and 1975. Incidence by stage included 17.3% for Stage I (75 cases) and 16.9% for Stage II (59 cases). Median survival by stage was not adversely a...

journal_title：Cancer

authors： Reynolds RD,Pajak TF,Greenberg BR,Shirley JH,Lucas RN,Hill RP,Schacht LR

更新日期：1978-12-01 00:00:00

abstract：BACKGROUND:Overall survival (OS) is considered the gold standard for determining treatment efficacy in oncology trials, but the relation between treatment and OS can be challenging to assess because of long study durations and the impact of subsequent therapies on outcome. Using OS can be particularly difficult for new...

journal_title：Cancer

authors： Smith BD,DeZern AE,Bastian AW,Durie BGM

更新日期：2017-05-15 00:00:00

abstract：:A 29-year-old man with metastatic extraadrenal pheochromocytoma developed paraplegia which reversed completely after megavoltage irradiation of the dorsolumbar spine. Later, treated with cyclophosphamide, vincristine, and dacarbazine, he had a temporary decrease in plasma norepinephrine concentration, a partial recalc...

journal_title：Cancer

authors： Siddiqui MZ,Von Eyben FE,Spanos G

更新日期：1988-08-15 00:00:00

abstract：BACKGROUND:Brain metastases from esophageal carcinoma are extremely rare, and information regarding the natural history, results of treatment, and possible prognostic factors in these patients is limited. METHODS:The records of 36 patients with brain metastases from esophageal carcinoma who were treated between 1986 a...

journal_title：Cancer

authors： Ogawa K,Toita T,Sueyama H,Fuwa N,Kakinohana Y,Kamata M,Adachi G,Saito A,Yoshii Y,Murayama S

更新日期：2002-02-01 00:00:00

abstract：:A pulmonary blastoma in a 52-year-old Japanese man was serially transplanted into athymic nude mice. This report emphasizes the characteristics of the neoplasm seen on light and electron microscopic examination. The original tumor consisted of branching tubular structures and primitive mesenchymal components with a fe...

journal_title：Cancer

authors： Tamai S,Kameya T,Shimosato Y,Tsumuraya M,Wada T

更新日期：1980-09-15 00:00:00

abstract：BACKGROUND:The pretherapy prediction of occult lymph node involvement and the avoidance of otherwise futile and potentially morbid definitive local therapy is paramount in men with newly diagnosed prostate carcinoma. To identify patients with prostate carcinoma who likely have lymph node involvement and would benefit f...

journal_title：Cancer

authors： Polascik TJ,Manyak MJ,Haseman MK,Gurganus RT,Rogers B,Maguire RT,Partin AW

更新日期：1999-04-01 00:00:00

abstract：:Seven hundred ninety-five patients were adenocarcinomas of the proximal colon were reviewed. Two hundred forty-five patients presented with disseminated disease at the time of diagnosis, and were analyzed to identify mechanisms and sites of disease spread. Five hundred fifty patients underwent radical resection, and w...

journal_title：Cancer

authors： Russell AH,Tong D,Dawson LE,Wisbeck W

更新日期：1984-01-15 00:00:00

abstract：BACKGROUND:Although cancer has become one of the leading health burdens, to the authors' knowledge, evidence regarding its relationship with a healthy lifestyle in the Chinese population remains limited. METHODS:The authors evaluated the association between clustering of healthy lifestyle factors and cancer risk using...

journal_title：Cancer

authors： Wang X,Yang X,Li J,Liu F,Chen J,Liu X,Cao J,Shen C,Yu L,Lu F,Wu X,Zhao L,Wu X,Li Y,Hu D,Huang J,Lu X,Gu D

更新日期：2019-06-15 00:00:00

abstract：BACKGROUND:To the authors' knowledge, relatively little is known regarding the interaction of risk factors for hepatocellular carcinoma (HCC) with age, sex, and liver disorder status. METHODS:The authors followed 504,646 Korean patients aged 40 to 80 years who underwent routine health checkups between 2002 and 2003 un...

journal_title：Cancer

authors： Yi SW,Choi JS,Yi JJ,Lee YH,Han KJ

更新日期：2018-07-01 00:00:00

abstract：:The prognostic significance of the pretreatment growth characteristics of marrow blasts was examined in 37 patients with acute nonlymphocytic leukemia (ANLL) treated with a similar therapeutic regimen. Initial mitotic index (MI) and in vitro 3H-thymidine labeling index (LI) were broadly distributed showing no correlat...

journal_title：Cancer

authors： Amadori S,Petti MC,De Francesco A,Chierichini A,Mastrovincenzo C,Testa MG,Mandelli F

更新日期：1978-03-01 00:00:00

abstract：:In 95 surgically staged patients with squamous cell carcinoma of the maxillary sinus, multivariate regression analyses were employed to identify prognostic factors. Possible prognostic factors for local control were TNM stage and type of surgical procedures: T2 or T3 tumors and use of total maxillectomy showed better ...

journal_title：Cancer

authors： Kondo M,Ogawa K,Inuyama Y,Yamashita S,Tominaga S,Shigematsu N,Nishiguchi I,Hashimoto S

更新日期：1985-01-01 00:00:00

abstract：:From a total of 874 patients with small cell lung cancer (SCC), a series of 104 patients were reviewed to determine if bone marrow relapses are detectable by routine clinical investigations. Autopsy, including microscopical bone marrow examination, was performed in all the 104 patients and bone metastases were disclos...

journal_title：Cancer

authors： Kristjansen PE,Osterlind K,Hansen M

更新日期：1986-12-01 00:00:00

abstract：BACKGROUND:The altered and anomalous expression of carbohydrate antigens (CA) occur in patients with lung carcinomas. METHODS:To investigate the relationship between prognosis and immunohistochemical findings of CA in serum and pulmonary adenocarcinomas (PA), PA specimens surgically resected from 102 patients were stu...

journal_title：Cancer

authors： Kawai T,Suzuki M,Kase K,Ozeki Y

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:Patients with American Joint Committee on Cancer Stage IV advanced pancreatic carcinoma have been treated by systemic chemotherapy, intraarterial chemotherapy, radiation therapy, and multidisciplinary treatment using a combination of these. However, the outcome has not always been satisfactory. In the curren...

journal_title：Cancer

authors： Homma H,Doi T,Mezawa S,Takada K,Kukitsu T,Oku T,Akiyama T,Kusakabe T,Miyanishi K,Niitsu Y

更新日期：2000-07-15 00:00:00

abstract：BACKGROUND:Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) plays an important role in the process of lymphocyte-mediated cytotoxicity against malignant cells. Osteoprotegerin (OPG) is a soluble decoy receptor for TRAIL, and circulating OPG has been implicated in the protection of cells from TRAIL-mediat...

journal_title：Cancer

authors： Mizutani Y,Matsubara H,Yamamoto K,Nan Li Y,Mikami K,Okihara K,Kawauchi A,Bonavida B,Miki T

更新日期：2004-10-15 00:00:00

abstract：BACKGROUND:The authors reviewed changes in the initial clinical presentation, management techniques, and patterns of disease recurrence over time (1981-1996) in patients with breast carcinoma treated with breast-conserving therapy (BCT) at a single institution. The goals of the current study were to determine the frequ...

journal_title：Cancer

authors： Pass H,Vicini FA,Kestin LL,Goldstein NS,Decker D,Pettinga J,Ingold J,Benitez P,Neumann K,Rebner M,Dekhne N,Martinez A

更新日期：2004-08-15 00:00:00

abstract：:Lobular carcinoma may arise within the epithelial component of fibroadenoma of the breast, as evidenced by 5 cases reported from the files of the Mayo Clinic and 21 cases cited in the literature. The 5 cases reported here occurred in a series of 4000 cases of fibroadenoma during a 43-year period. Lobular carcinoma is ...

journal_title：Cancer

authors： Buzanowski-Konakry K,Harrison EG Jr,Payne WS

更新日期：1975-02-01 00:00:00

abstract：BACKGROUND:Primary central nervous system lymphoma (PCNSL) is the most common brain tumor occurring in patients with acquired immune deficiency syndrome (AIDS). After diagnosis of PCNSL, the median survival time is 2-5 months with treatment with whole brain irradiation (WBI). METHODS:Four (of approximately 40) patient...

journal_title：Cancer

authors： Chamberlain MC

更新日期：1994-03-15 00:00:00

abstract：:The livers of 345 autopsy cases of chronic liver disease were examined for macroregenerative nodule (MRN), a large nodular lesion more than 10 mm in diameter. A total of 86 lesions of MRN was found in 49 cases (14.2%): 32 were from 191 cases of hepatocellular carcinoma (HCC), 16 were from 148 cases of cirrhosis only, ...

journal_title：Cancer

authors： Furuya K,Nakamura M,Yamamoto Y,Togei K,Otsuka H

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Aberrant DNA methylation, which results in leukemogenesis, is frequent in patients with myelodysplastic syndromes (MDS) and is a potential target for pharmacologic therapy. Decitabine indirectly depletes methylcytosine and causes hypomethylation of target gene promoters. METHODS:A total of 170 patients with...

journal_title：Cancer

authors： Kantarjian H,Issa JP,Rosenfeld CS,Bennett JM,Albitar M,DiPersio J,Klimek V,Slack J,de Castro C,Ravandi F,Helmer R 3rd,Shen L,Nimer SD,Leavitt R,Raza A,Saba H

更新日期：2006-04-15 00:00:00

abstract：:Cancer-related fatigue (CRF) has been documented as 1 of the most distressing symptoms reported by breast cancer survivors. CRF affects functioning and impacts quality of life. Possible causal factors include physical conditions, affective and cognitive states, proinflammatory cytokines, and metabolic factors. Several...

journal_title：Cancer

authors： Berger AM,Gerber LH,Mayer DK

更新日期：2012-04-15 00:00:00

abstract：:Nineteen postmenopausal patients with metastatic breast cancer refractory to conventional combination chemotherapy were treated with monthly cycles with the combinations of vinblastine, adriamycin, thiotepa and halotestin. Ten patients (52%) responded with a greater than 50% regression of measurable tumor. The median ...

journal_title：Cancer

authors： Perloff M,Hart RD,Holland JF

更新日期：1978-12-01 00:00:00