Prognostic factors influencing relapse of squamous cell carcinoma of the maxillary sinus.

Abstract:

:In 95 surgically staged patients with squamous cell carcinoma of the maxillary sinus, multivariate regression analyses were employed to identify prognostic factors. Possible prognostic factors for local control were TNM stage and type of surgical procedures: T2 or T3 tumors and use of total maxillectomy showed better local control rates (P less than 0.01). High radiation doses of 40 Gy or more also seemed to be of prognostic significance: P less than 0.2 for 40 to 60 Gy, and P less than 0.1 for 60 Gy or more. The risk of cervical relapse increased when the cheek or alveolus was grossly involved (P less than 0.2). However, since cervical relapse frequently accompanied uncontrollable primary recurrence or distant spread, and since cervical relapse alone was frequently salvaged by radical neck dissection, prophylactic irradiation to the neck is not recommended. Sex, age, nodal state, addition of chemotherapy, total doses of bleomycin or 5-fluorouracil (5-FU), or intra-arterial administration of chemotherapeutic agents did not appear to be of prognostic significance.

journal_name

Cancer

journal_title

Cancer

authors

Kondo M,Ogawa K,Inuyama Y,Yamashita S,Tominaga S,Shigematsu N,Nishiguchi I,Hashimoto S

doi

10.1002/1097-0142(19850101)55:1<190::aid-cncr28205

subject

Has Abstract

pub_date

1985-01-01 00:00:00

pages

190-6

issue

1

eissn

0008-543X

issn

1097-0142

journal_volume

55

pub_type

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