Beta-glucuronidase activity in prostatic carcinoma and benign prostatic hyperplasia.

Abstract:

:Beta-glucuronidase activity was extracted from prostatic carcinomas and hyperplastic prostates. It was 3.6-fold higher (P less than 0.0001) in prostatic carcinoma than in prostatic hyperplasia. Analysis for isoenzymes of prostatic beta-glucuronidase by disc-gel electrophoresis in nondenaturing polyacrylamide gels demonstrated only one form of the enzyme. Histochemically, enzymatic activity was observed almost entirely in epithelial cells in both prostatic carcinoma and benign prostatic hyperplasia.

journal_name

Cancer

journal_title

Cancer

authors

Pearson JP,Pretlow TP,Bradley EL Jr,McGinnis MC,Pretlow TG

doi

10.1002/1097-0142(19890815)64:4<911::aid-cncr28206

subject

Has Abstract

pub_date

1989-08-15 00:00:00

pages

911-5

issue

4

eissn

0008-543X

issn

1097-0142

journal_volume

64

pub_type

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