Beta-glucuronidase activity in prostatic carcinoma and benign prostatic hyperplasia.

abstract：BACKGROUND:Although the biologic characteristics of papillary cystic tumors (PCT) generally indicate a good prognosis, a malignant form has been reported. METHODS:Twenty-two examples of PCT were examined to assess their malignant potential by histologic, flow cytometric, and immunohistochemical studies. RESULTS:Three...

journal_title：Cancer

authors： Nishihara K,Nagoshi M,Tsuneyoshi M,Yamaguchi K,Hayashi I

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:The importance of the bone marrow microenvironment in multiple myeloma is receiving increasing attention. Recent studies have suggested the importance of cytokine production and cell-cell contact by bone marrow stromal cells in the survival of myeloma cells. METHODS:In the current study, the authors examine...

journal_title：Cancer

authors： Wallace SR,Oken MM,Lunetta KL,Panoskaltsis-Mortari A,Masellis AM

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:Receipt of chemotherapy at the end of life (EOL) is considered an indicator of poor quality of care for medical oncology. The objective of this study was to characterize the use of radiotherapy (RT) in patients with nonsmall cell lung cancer (NSCLC) during the same period. METHODS:Treatment characteristics ...

journal_title：Cancer

authors： Kapadia NS,Mamet R,Zornosa C,Niland JC,D'Amico TA,Hayman JA

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Recent scientific advances provide the opportunity to identify women in the general population at increased breast cancer risk and to offer effective early detection and disease prevention interventions. METHODS:A pedigree assessment tool (PAT) was designed to identify women in primary care settings who are...

journal_title：Cancer

authors： Hoskins KF,Zwaagstra A,Ranz M

更新日期：2006-10-15 00:00:00

abstract：BACKGROUND:Transitional cell carcinoma (TCC) is rare in the female genital tract. Although it is most common in the ovary, small series of cases in the cervix have been reported, with isolated cases described in the fallopian tube, adnexa uteri, and endometrium. METHODS:Eight cases of primary TCC involving the endomet...

journal_title：Cancer

authors： Lininger RA,Ashfaq R,Albores-Saavedra J,Tavassoli FA

更新日期：1997-05-15 00:00:00

abstract：BACKGROUND:The induction of estrogen and progesterone receptors (ER and PGR) has been reported in breast and endometrial cancer cells exposed to human fibroblast interferon-beta (hIFN-beta). Clinical verification of this finding might provide the rationale for new therapeutic approaches. This study was designed to eval...

journal_title：Cancer

authors： Codegoni AM,Landoni F,Lomonico S,Losa G,Mangioni C,Taverna M,Lucchini V,D'Incalci M

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND:Previous studies in the literature have suggested that radiolabeled F(ab')2 fragments might be superior to whole immunoglobulin G (IgG) for imaging and therapy of cancer because of their greater penetration in tumors. To test this hypothesis, the authors compared tumor and normal tissue uptake along with pla...

journal_title：Cancer

authors： Murray JL,Rosenblum MG,Zhang HZ,Podoloff DA,Kasi LP,Curley SA,Chan JC,Roh M,Hohn DC,Brewer H

更新日期：1994-02-01 00:00:00

abstract：:The 136 patients who underwent total laryngectomy as the primary treatment for squamous cell carcinoma of the glottis at the Mayo Clinic in 1970 through 1981 were followed by retrospective record review for at least 4 years or until death, local recurrence, neck recurrence, or delayed neck metastasis. Cancer recurred ...

journal_title：Cancer

authors： Foote RL,Buskirk SJ,Stanley RJ,Grambsch PM,Olsen KD,DeSanto LW,Earle JD,Weiland LH

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:The echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK) fusion gene resulting from the chromosome inversion inv(2)(p21;p23) recently was identified in nonsmall cell lung cancer (NSCLC). The authors of this study investigated the frequency, genetic and clinicopathologic prof...

journal_title：Cancer

authors： Wong DW,Leung EL,So KK,Tam IY,Sihoe AD,Cheng LC,Ho KK,Au JS,Chung LP,Pik Wong M,University of Hong Kong Lung Cancer Study Group.

更新日期：2009-04-15 00:00:00

abstract：:The current results of trials testing combined surgery and chemotherapy in patients with breast cancer is reviewed. Information concerning eight trials utilizing nine single-agent regimens was obtained. The results at this time are conflicting. There appear to be differences among the regimens utilized in the various ...

journal_title：Cancer

authors： Tormey DC

更新日期：1975-09-01 00:00:00

abstract：:Thirty-six patients with polycythemia vera were treated with hydroxyurea for 12 to 67 months. Nineteen patients were previously treated with other drugs. In the vast majority of patients, an average dose of 1 g/day was sufficient to control hematocrit value and platelet count. Half of the patients experienced relief o...

journal_title：Cancer

authors： Sharon R,Tatarsky I,Ben-Arieh Y

更新日期：1986-02-15 00:00:00

abstract：:A randomized study was designed to determine the effect of intermittent oral cyclophosphamide on the rate of metastases in children with localized and regional neuroblastoma. Secondary objectives of the study were to determine the value of the proposed staging system, to measure the influence of the peripheral lymphoc...

journal_title：Cancer

authors： Evans AE,Albo V,D'Angio GJ,Finklestein JZ,Leiken S,Santulli T,Weiner J,Hammond GD

更新日期：1976-08-01 00:00:00

abstract：BACKGROUND:Conditional survival is clinically useful, particularly for patients with malignant disease who have a poor prognosis. However, there are no published data on the conditional median survival of patients with advanced carcinoma on a population basis. METHODS:Data on 217,573 patients with breast, colorectal, ...

journal_title：Cancer

authors： Kato I,Severson RK,Schwartz AG

更新日期：2001-10-15 00:00:00

abstract：LAY SUMMARY:Cancer has substantial economic impacts for patients, their families and/or caregivers, employers, and the health care system. However, there is only limited understanding of how economic issues can affect access to cancer care services and the receipt of high-quality cancer care. Health economics research ...

journal_title：Cancer

authors： Halpern MT,Shih YT,Yabroff KR,Ekwueme DU,Bradley CJ,Davidoff AJ,Sabik LM,Lipscomb J

更新日期：2020-11-25 00:00:00

abstract：BACKGROUND:Human papillomaviruses (HPVs) commonly cause proliferative lesions of squamous epithelia, and infection with certain HPV types carries a high risk of malignant transformation, especially in the uterine cervix but also at other sites, including the esophagus. We used molecular techniques to detect and type HP...

journal_title：Cancer

authors： West AB,Soloway GN,Lizarraga G,Tyrrell L,Longley JB

更新日期：1996-06-15 00:00:00

abstract：:Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of severe immune activation and dysregulation resulting in extreme and often life-threatening inflammation. HLH has been well recognized in pediatric populations, and most current diagnostic and therapeutic guidelines are based on pediatric HLH. Recently there has...

journal_title：Cancer

authors： Daver N,McClain K,Allen CE,Parikh SA,Otrock Z,Rojas-Hernandez C,Blechacz B,Wang S,Minkov M,Jordan MB,La Rosée P,Kantarjian HM

更新日期：2017-09-01 00:00:00

abstract：:A case of biliary cystadenoma undergoing malignant dedifferentiation is presented. Biliary cystadenocarcinoma is an infrequently occurring neoplasm; fewer than 20 cases have been reported in the literature. This case is the first in which there is documentation of cystadenocarcinoma arising from a previously diagnosed...

journal_title：Cancer

authors： Woods GL

更新日期：1981-06-15 00:00:00

abstract：:The long-term effect of cisplatin on renal function was studied in a follow-up investigation, 16 to 52 months after chemotherapy in 22 patients with disseminated nonseminomatous testicular cancer. The median cumulated cisplatin dose was 452 mg/m2 (range, 275-650 mg/m2). Prehydration with isotonic saline secured diures...

journal_title：Cancer

authors： Fjeldborg P,Sørensen J,Helkjaer PE

更新日期：1986-11-15 00:00:00

abstract：BACKGROUND:Outcomes have improved significantly in multiple myeloma (MM), but racial disparities in health care access and survival exist. A comprehensive analysis exploring MM care and racial disparities is warranted. METHODS:Patients with MM from 1991 to 2010 in the Surveillance, Epidemiology, and End Results-Medica...

journal_title：Cancer

authors： Ailawadhi S,Frank RD,Sharma M,Menghani R,Temkit M,Paulus S,Khera N,Hashmi S,Advani P,Swaika A,Paulus A,Aslam N,Sher T,Roy V,Colon-Otero G,Chanan-Khan A

更新日期：2018-04-15 00:00:00

abstract：:To determine the quality of survival for children with posterior fossa tumors, comprehensive neuropsychological, behavioral, and academic assessment and physician ratings of functional status were obtained on 15 brain tumor patients (ages 6-19 years) at a median of 20 months post-diagnosis. More than 50% of the childr...

journal_title：Cancer

authors： LeBaron S,Zeltzer PM,Zeltzer LK,Scott SE,Marlin AE

更新日期：1988-09-15 00:00:00

abstract：:Various dose-time treatment plans have been used to obtain long duration pain relief in patients with metastatic bone disease. Very little has appeared in the literature evaluating the relationship of dose and fractionation to initial, delayed and permanent bone pain relief. At the Swedish Hospital Tumor Institute, 15...

journal_title：Cancer

authors： Allen KL,Johnson TW,Hibbs GG

更新日期：1976-02-01 00:00:00

abstract：BACKGROUND:It is believed that in the early stages of hepatocarcinogenesis, some adenomatous hyperplasias (AH) progress to early hepatocellular carcinoma (eHCC), and that many eHCC develop into overt hepatocellular carcinoma (HCC) through nodule-in-nodule formation. However, the proliferative activity of these small no...

journal_title：Cancer

authors： Aoki K,Sakamoto M,Hirohashi S

更新日期：1994-01-15 00:00:00

abstract：BACKGROUND:Gene expression profiling should be applicable to needle biopsy samples if microarray technology is to become practically useful for clinical research or management of breast carcinoma. This study compared gene expression profiles derived from fine-needle aspiration biopsy (FNAB) and from core needle biopsy ...

journal_title：Cancer

authors： Symmans WF,Ayers M,Clark EA,Stec J,Hess KR,Sneige N,Buchholz TA,Krishnamurthy S,Ibrahim NK,Buzdar AU,Theriault RL,Rosales MF,Thomas ES,Gwyn KM,Green MC,Syed AR,Hortobagyi GN,Pusztai L

更新日期：2003-06-15 00:00:00

abstract：BACKGROUND:Since mid-1987, 29 patients with invasive transitional cell carcinoma of the urinary bladder (T1-3 N0-X M0) were treated with concurrent radiation therapy (RT) (target dose [TD], 62-66 Gy) 1.8-2.0 Gy/day for 5 days a week with a break in the middle of treatment of 2-3 weeks and vinblastine weekly 2 mg/5-12 h...

journal_title：Cancer

authors： Kragelj B,Jereb B,Kragelj L,Stanonik M

更新日期：1992-12-15 00:00:00

abstract：BACKGROUND:Patients with American Joint Committee on Cancer Stage IV advanced pancreatic carcinoma have been treated by systemic chemotherapy, intraarterial chemotherapy, radiation therapy, and multidisciplinary treatment using a combination of these. However, the outcome has not always been satisfactory. In the curren...

journal_title：Cancer

authors： Homma H,Doi T,Mezawa S,Takada K,Kukitsu T,Oku T,Akiyama T,Kusakabe T,Miyanishi K,Niitsu Y

更新日期：2000-07-15 00:00:00

abstract：BACKGROUND:Cystic lesions of the adrenal gland are uncommon and demonstrate a spectrum of histologic changes and may vary from pseudocysts to malignant cystic neoplasms. METHODS:The authors analyzed a series of primary cystic lesions of the adrenal gland to evaluate the clinicopathologic features and histologic spectr...

journal_title：Cancer

authors： Erickson LA,Lloyd RV,Hartman R,Thompson G

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:The objective of this study was to examine the source of advanced cancer patients' information about their prognosis and determine whether this source of information could explain racial disparities in the accuracy of patients' life expectancy estimates (LEEs). METHODS:Coping With Cancer was a prospective, ...

journal_title：Cancer

authors： Trevino KM,Zhang B,Shen MJ,Prigerson HG

更新日期：2016-06-15 00:00:00

abstract：BACKGROUND:Aggressive angiomyxoma is an uncommon mesenchymal tumor that preferentially involves the pelvic and perineal regions of females. Since its initial description in 1983, approximately 65 cases have been reported in the English literature. METHODS:The clinical and pathologic features of 29 cases of aggressive ...

journal_title：Cancer

authors： Fetsch JF,Laskin WB,Lefkowitz M,Kindblom LG,Meis-Kindblom JM

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND:Reconstruction is rarely incorporated into the decision-making process for surgical breast cancer treatment. We examined the importance of knowing about reconstruction to patients' surgical decision-making for breast cancer. METHODS:We surveyed women aged < or =79 years with breast cancer (N = 1844) who wer...

journal_title：Cancer

authors： Alderman AK,Hawley ST,Waljee J,Mujahid M,Morrow M,Katz SJ

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Although several refinements have been reported for breast magnetic resonance imaging (MRI), there has been no uniform agreement by researchers on the optimal method. The authors report a simple and effective MRI method that incorporated the best qualities of other breast MRI methods yet eliminated the compl...

journal_title：Cancer

authors： Khatri VP,Stuppino JJ,Espinosa MH,Pollack MS

更新日期：2001-08-01 00:00:00