Radiation therapy at the end of life in patients with incurable nonsmall cell lung cancer.

abstract：BACKGROUND:As we approach the 21st century, clinically useful predictive models for prostate carcinoma are urgently needed to stratify patients reliably for future treatment strategies. Recently, many investigators have developed models that employ prostate specific antigen (PSA)-based constructs or groupings in an att...

journal_title：Cancer

authors： Movsas B,Hanlon AL,Teshima T,Hanks GE

更新日期：1997-09-15 00:00:00

abstract：BACKGROUND:Rapid tumor growth is caused by angiogenesis factors, growth factors, etc. We previously reported a possible connection between nitric oxide (NO) and enhanced vascular permeability in solid tumor. In the present experiment, the role of NO in solid tumor pathology was further investigated in animal tumor. ME...

journal_title：Cancer

authors： Doi K,Akaike T,Horie H,Noguchi Y,Fujii S,Beppu T,Ogawa M,Maeda H

更新日期：1996-04-15 00:00:00

abstract：BACKGROUND:Aggressive non-Hodgkin's lymphoma is now often curable with chemotherapy. The International Prognostic Index (IPI) was recently developed to predict patient survival on the basis of pretreatment clinical features. However, classical multivariate regression models such as the IPI fail to detect time-dependent...

journal_title：Cancer

authors： Mounier N,Morel P,Haioun C,Coiffier B,Tilly H,Chatelain C,Lederlin P,Thyss A,Herbrecht R,Gisselbrecht C,Lepage E

更新日期：1998-05-15 00:00:00

abstract：:This study concerns 75 patients with squamous cell carcinoma of the oral cavity who were patients at the Gustave-Roussy Institute between December 1966 and July 1973. These patients were divided into two groups. The first group was comprised of 39 patients who underwent elective radical neck dissection; nodal involvem...

journal_title：Cancer

authors： Vandenbrouck C,Sancho-Garnier H,Chassagne D,Saravane D,Cachin Y,Micheau C

更新日期：1980-07-15 00:00:00

abstract：BACKGROUND:Although lenalidomide maintenance therapy has demonstrated improved outcomes after autologous hematopoietic stem cell transplantation (auto-HCT) for patients with multiple myeloma (MM), the impact of the duration of this therapy is not clearly known. METHODS:This study retrospectively analyzed all MM patien...

journal_title：Cancer

authors： Mian I,Milton DR,Shah N,Nieto Y,Popat UR,Kebriaei P,Parmar S,Oran B,Shah JJ,Manasanch EE,Orlowski RZ,Shpall EJ,Champlin RE,Qazilbash MH,Bashir Q

更新日期：2016-12-15 00:00:00

abstract：:We present a case with the unusual association of Graves' disease and functioning pulmonary metastases of follicular thyroid carcinoma. Unlike other reports of thyroid cancer and thyrotoxicosis, this patient's hyperthyroidism was related to a hyperfunctioning primary thyroid neoplasm and not merely to large amounts of...

journal_title：Cancer

authors： Grayzel EF,Bennett B

更新日期：1979-05-01 00:00:00

abstract：:The clinical, histological, and ultrastructural aspects of a cervical paraganglioma of the vagus nerve, in a 66-year-old white man, have been discussed in detail. Ultrastructurally, the tumor chief cells contained characteristic membrane-bound and dense-cored neurosecretory granules which ranged in size from 85 millim...

journal_title：Cancer

authors： Chaudhry AP,Haar JG,Koul A,Nickerson PA

更新日期：1979-05-01 00:00:00

abstract：BACKGROUND:Workload is extensively regulated and often used as a measure of quality in gynecologic cytology. Whether workload correlates with the sensitivity of screening in gynecologic cytology is not known. METHODS:The sensitivity of gynecologic cytology screening was measured over an 8-month period using the result...

journal_title：Cancer

authors： Deschenes M,Renshaw AA,Auger M

更新日期：2008-06-25 00:00:00

abstract：BACKGROUND:The authors suggested that the loss of collagen IV and laminin-containing basement membrane and the loss of Disabled-2 (Dab2) expression were two critical events associated with morphologic dysplastic changes of the ovarian surface epithelium as a step in tumorigenicity. Both the basement membrane and Dab2, ...

journal_title：Cancer

authors： Roland IH,Yang WL,Yang DH,Daly MB,Ozols RF,Hamilton TC,Lynch HT,Godwin AK,Xu XX

更新日期：2003-12-15 00:00:00

abstract：BACKGROUND:The authors tested a biotherapy regimen involving recombinant interferon-alpha-2a (rIFN-alpha-2a) and recombinant human interleukin-2 (rhIL-2), given in a "decrescendo" schedule over 5 days, for its activity and toxicity in 21 patients who previously had received chemotherapy for advanced melanoma. METHODS:...

journal_title：Cancer

authors： Eton O,Buzaid AC,Bedikian AY,Smith TM,Papadopoulos NE,Ellerhorst JA,Hibberts JL,Legha SS,Benjamin RS

更新日期：2000-04-01 00:00:00

abstract：BACKGROUND:It has been previously observed that patients with head and neck squamous cell carcinoma or with laryngeal leucoplakia present a significant reduction in plasma folate levels. The current Phase IIA pilot study assessed the effectiveness of folic acid as a chemopreventive agent in patients affected by glottic...

journal_title：Cancer

authors： Almadori G,Bussu F,Navarra P,Galli J,Paludetti G,Giardina B,Maurizi M

更新日期：2006-07-15 00:00:00

abstract：BACKGROUND:The Female Sexual Function Index (FSFI) is the most commonly used self-report instrument to measure sexual functioning among women cancer survivors. Despite this, the validity and reliability of the FSFI for use in cancer populations has not been established. METHODS:Data were combined from 3 separate insti...

journal_title：Cancer

authors： Baser RE,Li Y,Carter J

更新日期：2012-09-15 00:00:00

abstract：BACKGROUND:The purpose of the current study was to determine the frequency of 'probably benign' interpretations at breast magnetic resonance (MR) imaging screening of high-risk women and the frequency of subsequent malignancy in these women. METHODS:The authors performed a retrospective review of the records of 367 as...

journal_title：Cancer

authors： Liberman L,Morris EA,Benton CL,Abramson AF,Dershaw DD

更新日期：2003-07-15 00:00:00

abstract：BACKGROUND:To assess whether the effectiveness of a combination of transcatheter arterial chemoembolization (TACE) and percutaneous ethanol injection (PEI) is superior to PEI alone in the treatment of patients with small hepatocellular carcinoma (HCC), a randomized controlled study was performed. METHODS:Fifty-two pat...

journal_title：Cancer

authors： Koda M,Murawaki Y,Mitsuda A,Oyama K,Okamoto K,Idobe Y,Suou T,Kawasaki H

更新日期：2001-09-15 00:00:00

abstract：BACKGROUND:Colorectal carcinoma (CRC) may be the most frequent form of hereditary cancer. Genetic counseling and testing for heritable CRC is a promising approach for reducing the high incidence and mortality rates associated with the disease. Patients with CRC or those with at least one family member with the disease ...

journal_title：Cancer

authors： Kinney AY,DeVellis BM,Skrzynia C,Millikan R

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Ewing's sarcomas, osteosarcomas, and rhabdomyosarcomas are significantly more responsive to chemotherapy than other sarcomas. Adjuvant chemotherapy is used routinely based on data from randomized trials. Although a percentage of children with locally advanced or metastatic tumors remain curable, few data exi...

journal_title：Cancer

authors： Antman K,Crowley J,Balcerzak SP,Kempf RA,Weiss RB,Clamon GH,Baker LH

更新日期：1998-04-01 00:00:00

abstract：:Forty-three patients with evaluable metastatic breast cancer refractory to hormonal agents and extensive combination chemotherapy including doxorubicin were treated with mitomycin, 20 mg/m2 intravenously every 6 weeks. There were five partial responses (12%) and three minor responses (7%), with a mean time to progress...

journal_title：Cancer

authors： Pasterz RB,Buzdar AU,Hortobagyi GN,Blumenschein GR

更新日期：1985-11-15 00:00:00

abstract：:Irreversible and progressive renal parenchymal damage and functional impairment occurred in the majority of patients receiving at least six courses (200 mg/m2 of BCNU and/or methyl CCNU at eight-week intervals) of nitrosoureas for therapy of malignant brain tumors. Seventeen of 18 patients who received at least six co...

journal_title：Cancer

authors： Schacht RG,Feiner HD,Gallo GR,Lieberman A,Baldwin DS

更新日期：1981-09-15 00:00:00

abstract：:Carcinoembryonic antigen (CEA) values in 529 patients treated in two consecutive adjuvant chemotherapy protocols were analyzed to determine if CEA values correlated with disease-free status or prognostic utility. CEA values were evaluated preoperatively, before chemotherapy, at the conclusion of chemotherapy, and duri...

journal_title：Cancer

authors： Theriault RL,Hortobagyi GN,Fritsche HA,Frye D,Martinez R,Buzdar AU

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND:Multicentric breast carcinomas have a higher frequency of axillary lymph node metastasis than unifocal tumors of similar stage. It remains unclear whether this merely reflects larger tumor volumes or a different biologic behavior. The authors have shown previously that when aggregate tumor diameter are used ...

journal_title：Cancer

authors： Andea AA,Bouwman D,Wallis T,Visscher DW

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Since mid-1987, 29 patients with invasive transitional cell carcinoma of the urinary bladder (T1-3 N0-X M0) were treated with concurrent radiation therapy (RT) (target dose [TD], 62-66 Gy) 1.8-2.0 Gy/day for 5 days a week with a break in the middle of treatment of 2-3 weeks and vinblastine weekly 2 mg/5-12 h...

journal_title：Cancer

authors： Kragelj B,Jereb B,Kragelj L,Stanonik M

更新日期：1992-12-15 00:00:00

abstract：:Five patients with angiosarcoma of the breast were treated with surgery, radiotherapy and an adjuvant Adriamycin containing regimen. Two patients remain disease-free at 38+ and 20+ months. The median survival of previously reported cases is 22 months with only five patients disease-free at five years. Possible hormona...

journal_title：Cancer

authors： Antman KH,Corson J,Greenberger J,Wilson R

更新日期：1982-11-15 00:00:00

abstract：BACKGROUND:In multidisciplinary assessment clinics for screen-detected breast lesions, onsite cytopathologists provide immediate results of fine-needle aspiration biopsies (FNABs) and this information is used for patient counseling and treatment planning. Such consultation is not possible for the increasing proportion ...

journal_title：Cancer

authors： Farshid G,Pieterse S

更新日期：2006-06-25 00:00:00

abstract：BACKGROUND:Significant antitumor effects were previously observed with radioimmunotherapy (RIT) using an anti-carcinoembryonic antigen (CEA) monoclonal antibody (F6) labeled with iodine-131 in medullary thyroid cancer (MTC)-bearing nude mice. Nevertheless, no complete response was achieved. Because angiogenesis is crit...

journal_title：Cancer

authors： Salaun PY,Bodet-Milin C,Frampas E,Oudoux A,Saï-Maurel C,Faivre-Chauvet A,Barbet J,Paris F,Kraeber-Bodéré F

更新日期：2010-02-15 00:00:00

abstract：:The use of preoperative computed tomographic (CT) scans of the chest in carcinoma of the esophagus to associate preoperative staging with postoperative survival is controversial. Thirty-two patients who underwent esophagectomy and reconstruction were examined with respect to a variety of variables available on preoper...

journal_title：Cancer

authors： Lefor AT,Merino MM,Steinberg SM,Dwyer A,Roth JA,Flanagan M,Pass HI

更新日期：1988-10-01 00:00:00

abstract：:Various attempts have been made to improve the effectiveness of radiation in the treatment of cerebral malignant astrocytomas. A trend favoring multiple daily fractionated (MDF) radiation therapy over conventional single daily fractionated (CF) radiation therapy was identified in our previous study. In order to assess...

journal_title：Cancer

authors： Shin KH,Urtasun RC,Fulton D,Geggie PH,Tanasichuk H,Thomas H,Muller PJ,Curry B,Mielke B,Johnson E

更新日期：1985-08-15 00:00:00

abstract：BACKGROUND:Men who receive androgen-deprivation therapy (ADT) for prostate cancer experience several side effects from this treatment. A few recent studies have examined the cognitive implications of ADT and how they impact a patient's treatment decision-making, occupational pursuits, and quality of life. For this repo...

journal_title：Cancer

authors： Nelson CJ,Lee JS,Gamboa MC,Roth AJ

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Inflammatory parameters as acute phase proteins commonly are elevated in patients with renal cell carcinoma. Some of these acute phase reactants have been proposed to influence survival. METHODS:In 170 patients with renal cell carcinoma, the authors studied six acute phase reactant parameters (erythrocyte s...

journal_title：Cancer

authors： Ljungberg B,Grankvist K,Rasmuson T

更新日期：1995-10-15 00:00:00

abstract：BACKGROUND:Cancer cell expression of costimulatory molecule B7-H1 has been implicated as a potent inhibitor of T-cell-mediated antitumoral immunity. The authors recently reported that B7-H1 is aberrantly expressed in primary renal cell carcinoma (RCC). Blockade of B7-H1, as demonstrated in several murine cancer models,...

journal_title：Cancer

authors： Thompson RH,Gillett MD,Cheville JC,Lohse CM,Dong H,Webster WS,Chen L,Zincke H,Blute ML,Leibovich BC,Kwon ED

更新日期：2005-11-15 00:00:00

abstract：:The authors describe a new technique for the subcutaneous heterotopic transplantation of the ovary before pelvic irradiation to treat Hodgkin's disease. Creation of a cavity to receive the transplant and the use of two surgical teams and the surgical microscope during the operation ensured its successful outcome. The ...

journal_title：Cancer

authors： Leporrier M,von Theobald P,Roffe JL,Muller G

更新日期：1987-11-01 00:00:00