Pilot phase IIA study for evaluation of the efficacy of folic acid in the treatment of laryngeal leucoplakia.

abstract：BACKGROUND:Approximately 5% of clear cell renal cell carcinomas contain components with sarcomatoid differentiation. It has been suggested that the sarcomatoid elements arise from the clear cell tumors as a consequence of clonal expansions of neoplastic cells with progressively more genetic alterations. Analysis of the...

journal_title：Cancer

authors： Jones TD,Eble JN,Wang M,Maclennan GT,Jain S,Cheng L

更新日期：2005-09-15 00:00:00

abstract：:A patient with metastatic islet cell carcinoma of the pancreas, recurrent peptic ulcer disease, and hypergastrinemia (Zollinger-Ellison syndrome) developed symptomatic hypercalcemia and renal insufficiency; she was treated with streptozotocin after parathyroidectomy failed to control her hypercalcemia. Shortly after s...

journal_title：Cancer

authors： Cryer PE,Hill GJ II

更新日期：1976-12-01 00:00:00

abstract：:Three children with ALL having poor prognostic features developed clinical and laboratory evidence of disseminated intravascular coagulation (DIC). Two developed a bleeding diathesis associated temporally with a rapid drop in blast cell counts during induction therapy with L-asparaginase, prednisone, and vincristine. ...

journal_title：Cancer

authors： Champion LA,Luddy RE,Schwartz AD

更新日期：1978-04-01 00:00:00

abstract：:The medical records of 243 patients admitted over a five-year period with a diagnosis of carcinoma of the cervix were reviewed to determine (1) the frequency of pulmonary metastasis, (2) the relationship between the stage of the primary lesion and the incidence of pulmonary metastasis, and (3) the relationship between...

journal_title：Cancer

authors： Tellis CJ,Beechler CR

更新日期：1982-04-15 00:00:00

abstract：:Since 1981, 20 patients with anaplastic giant cell carcinoma of the thyroid have been prospectively treated according to a combination regimen of chemotherapy and external beam radiation therapy. Two types of chemotherapy were used every 4 weeks, depending on the patient's age. For those younger than 65 years, a combi...

journal_title：Cancer

authors： Schlumberger M,Parmentier C,Delisle MJ,Couette JE,Droz JP,Sarrazin D

更新日期：1991-02-01 00:00:00

abstract：:The authors report on five patients with secondary leukemia (SL) and one of the "specific" chromosomal rearrangements usually encountered in de novo acute nonlymphoblastic leukemia: inv(16), t(15;17), t(8;21), and t(9;11). They were characterized by solid tumor as the primary malignancy in four of five cases, absence ...

journal_title：Cancer

authors： Fenaux P,Lucidarme D,Laï JL,Bauters F

更新日期：1989-06-15 00:00:00

abstract：BACKGROUND:A large amount of interindividual variability exists in the occurrence of symptoms in patients receiving chemotherapy (CTX). The purposes of the current study, which was performed in a sample of 582 oncology outpatients who were receiving CTX, were to identify subgroups of patients based on their distinct ex...

journal_title：Cancer

authors： Miaskowski C,Cooper BA,Melisko M,Chen LM,Mastick J,West C,Paul SM,Dunn LB,Schmidt BL,Hammer M,Cartwright F,Wright F,Langford DJ,Lee K,Aouizerat BE

更新日期：2014-08-01 00:00:00

abstract：:The current study determines the prognostic factors after hepatectomy for hepatocellular carcinomas. The 295 patients who underwent hepatectomy from 1973 through 1987 were included for a univariate and a Cox multivariate analysis. The favoring conditions were determined as follows. The essential requirements are (1) t...

journal_title：Cancer

authors： Yamanaka N,Okamoto E,Toyosaka A,Mitunobu M,Fujihara S,Kato T,Fujimoto J,Oriyama T,Furukawa K,Kawamura E

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:Endometrial carcinoma is one of the most frequent malignancies in the female genital tract, and its incidence has been increasing in Japan. Histologic grade is an important factor for organizing treatment strategies, including hormone therapy, and for predicting the prognosis of the patient. The objective of...

journal_title：Cancer

authors： Nishimura Y,Watanabe J,Jobo T,Hattori M,Arai T,Kuramoto H

更新日期：2005-02-25 00:00:00

abstract：:For 52 patients with depressed adenomas of the stomach, histopathologic studies were done on 56 tumors and for 43 of them, histochemical and immunohistochemical features were examined. In addition, nondepressed adenomas (n = 57) and the depressed type of early gastric adenocarcinomas of the well-differentiated variety...

journal_title：Cancer

authors： Xuan ZX,Ambe K,Enjoji M

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND:Inflammatory parameters as acute phase proteins commonly are elevated in patients with renal cell carcinoma. Some of these acute phase reactants have been proposed to influence survival. METHODS:In 170 patients with renal cell carcinoma, the authors studied six acute phase reactant parameters (erythrocyte s...

journal_title：Cancer

authors： Ljungberg B,Grankvist K,Rasmuson T

更新日期：1995-10-15 00:00:00

abstract：:Flow cytometry examinations (FCM) were carried out on 110 bladder irrigation specimens from 84 urologic outpatients who had had prior conservative treatment for low stage bladder tumors. The specimens were easily obtained, and adequately cellular in all cases. Of 60 examinations on patients with no cytoscopic abnormal...

journal_title：Cancer

authors： Devonec M,Darzynkiewicz Z,Kostyrka-Claps ML,Collste L,Whitmore WF Jr,Melamed MR

更新日期：1982-01-01 00:00:00

abstract：:Results of remission induction therapy in refractory acute nonlymphocytic leukemia (ANLL) has been improved since the introduction of high-dose cytosine arabinoside. However, the toxicity of these regimens attributes to an early death rate of about 20% to 30%. The authors treated 37 poor-risk patients with ANLL with i...

journal_title：Cancer

authors： Dekker AW,Nieuwenhuis HK,Verdonck LF

更新日期：1990-05-01 00:00:00

abstract：:Two groups of children with refractory acute lymphoblastic leukemia were treated with a regimen of methotrexate (MTX) and asparaginase (Asn'ase) based on studies of the effect of MTX in vitro on human lymphoblasts exposed to Asn'ase. Induction therapy in 12 children produced 4 complete remissions, 3 partial remissions...

journal_title：Cancer

authors： Lobel JS,O'Brien RT,McIntosh S,Aspnes GT,Capizzi RL

更新日期：1979-03-01 00:00:00

abstract：:Primary splenic angiosarcomas are rare neoplasms. The diagnosis can only be made at surgery. Splenectomy prior to rupture prolongs survival. An unusual case report is presented and the literature reviewed. ...

journal_title：Cancer

authors： Smith VC,Eisenberg BL,McDonald EC

更新日期：1985-04-01 00:00:00

abstract：BACKGROUND:: Although platinum-based combinations are considered the best option of care for patients with advanced nonsmall cell lung cancer (NSCLC), single-agent therapy is the preferred treatment for older patients. Since the late 1990s, various combinations of third-generation agents (gemcitabine [G], vinorelbine, ...

journal_title：Cancer

authors： Russo A,Rizzo S,Fulfaro F,Adamo V,Santini D,Vincenzi B,Gebbia N,Carreca I

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:The benefits of an active lifestyle after a breast cancer diagnosis are well recognized, but the majority of survivors are insufficiently active. The ACTIVATE Trial examined the efficacy of an intervention (use of the Garmin Vivofit 2 activity monitor coupled with a behavioral feedback and goal-setting sessi...

journal_title：Cancer

authors： Lynch BM,Nguyen NH,Moore MM,Reeves MM,Rosenberg DE,Boyle T,Vallance JK,Milton S,Friedenreich CM,English DR

更新日期：2019-08-15 00:00:00

abstract：BACKGROUND:Vascular endothelial growth factor (VEGF) signaling is a target for antiangiogenic cancer therapy. The authors have previously observed that up to 40% of vessels in colorectal carcinoma (CRC) tumors are negative for VEGF receptor 2 (VEGFR2) expression. Differential activity of transforming growth factor beta...

journal_title：Cancer

authors： Kuczynski EA,Viloria-Petit AM,Coomber BL

更新日期：2011-12-15 00:00:00

abstract：:To investigate the possible implications of heterogeneity among the non-Hodgkin's lymphomas for bone marrow purging using complement-fixing monoclonal antibodies to lymphoma-associated antigens, a panel of large cell lymphoma cell lines of diverse phenotypes was treated with monoclonal antibodies DLC-48 and LN-1. An a...

journal_title：Cancer

authors： Winter JN,Marder RJ,Mankad B,Epstein AL

更新日期：1988-03-15 00:00:00

abstract：BACKGROUND:Patient navigation may reduce cancer disparities associated with socioeconomic status (SES) and household factors. This study examined whether these factors were associated with delays in diagnostic resolution among patients with cancer screening abnormalities and whether patient navigation ameliorated these...

journal_title：Cancer

authors： Rodday AM,Parsons SK,Snyder F,Simon MA,Llanos AA,Warren-Mears V,Dudley D,Lee JH,Patierno SR,Markossian TW,Sanders M,Whitley EM,Freund KM

更新日期：2015-11-15 00:00:00

abstract：:In this report, the authors describe an innovative antitobacco advertising campaign in Arizona that was aimed at youth. The campaign utilizes traditional as well as non-traditional methods of research to determine the attitudes, behavior and values of today's adolescents. These creative methodologies led to rigorously...

journal_title：Cancer

authors： Riester T,Linton M

更新日期：1998-12-15 00:00:00

abstract：:The possible influence of histologic grade, necrosis and size of invasive breast cancers on the five year survival rate of women treated in NSABP clinical trials with regimens of L-PAM (P) and L-PAM + 5-FU (PF) and for four years in those receiving L-PAM + 5-FU + methotrexate (PMF) was investigated. Generally, all reg...

journal_title：Cancer

authors： Fisher ER,Redmond C,Fisher B

更新日期：1983-01-15 00:00:00

abstract：BACKGROUND:Colorectal cancer patients undergoing chemotherapy (CT) are likely to experience multiple concurrent toxicities that, rather than appearing singularly, may be associated with one another. Graphic and tabular representations of distance matrices were used to identify associations between toxicities and to def...

journal_title：Cancer

authors： Aprile G,Ramoni M,Keefe D,Sonis S

更新日期：2008-01-15 00:00:00

abstract：:A case of pancreatoblastoma, arising in the tail of the pancreas with metastases to the right radius, in an 8-year-old boy is reported. The serum alpha-fetoprotein (AFP) level was over 13 times the normal value before surgery, but returned to normal after removal of the primary tumor. Furthermore, AFP was detected in ...

journal_title：Cancer

authors： Iseki M,Suzuki T,Koizumi Y,Hirose M,Laskin WB,Nakazawa S,Ohaki Y

更新日期：1986-05-01 00:00:00

abstract：BACKGROUND:Chemotherapy improves survival for patients with stage III colon cancer, but some older patients with lymph node-positive colon cancer do not see a medical oncologist and, thus, do not receive adjuvant chemotherapy. METHODS:To evaluate the role of the surgeon in determining referrals to medical oncology amo...

journal_title：Cancer

authors： Luo R,Giordano SH,Zhang DD,Freeman J,Goodwin JS

更新日期：2007-03-01 00:00:00

abstract：:A case-referent study on soft tissue sarcomas (STS) was conducted, to see if previous findings regarding an association between exposure to phenoxyacetic acids or chlorophenols and this tumor type could be reproduced. Fifty-five male STS patients were thereby compared with 220 living and 110 dead population-based refe...

journal_title：Cancer

authors： Hardell L,Eriksson M

更新日期：1988-08-01 00:00:00

abstract：:A case of thymoma in a 12-year-old boy is presented. The patient had a history of thymic irradiation in infancy, and a family history of leukemia. The mass was readily resected and the patient is well 10 years later. The tumor contained an unusual admixture of normal thymic tissue with the neoplastic epithelial elemen...

journal_title：Cancer

authors： Chatten J,Katz SM

更新日期：1976-02-01 00:00:00

abstract：:Proviral DNA of adult T-cell leukemia virus (HTLV-I) was examined by the standard Southern blotting method in lymph nodes of 45 patients with anti-HTLV-I antibody (ATLA)-positive adult T-cell leukemia/lymphoma (ATLL). Six of these patients revealed no monoclonal proviral HTLV-I DNA in tumor cells. These six patients s...

journal_title：Cancer

authors： Yoshida T,Kikuchi M,Ooshima K,Takeshita M,Kimura N,Kozuru M,Satoh H

更新日期：1989-12-15 00:00:00

abstract：:A possible association between gallstones, colorectal cancer, and gastric cancer was investigated. The age distribution and mean age of the two cancer groups were identical. The incidence of gallstones in 378 colorectal cancer cases and 869 gastric cancer cases was 7.1% and 5.5%, respectively. Of colorectal cancer cas...

journal_title：Cancer

authors： Narisawa T,Yamazaki Y,Kusaka H,Takahashi M,Kotanagi H,Koyama K

更新日期：1991-03-15 00:00:00

abstract：:We synthesized doxorubicin (Adriamycin, Adria Laboratories, Columbus, OH)-loaded human albumin microspheres (containing approximately 1% doxorubicin w/w) between 15 and 20 micron in diameter. Intrarenal arterial administration of 99mTC-labeled microspheres demonstrated a high renal entrapment ratio (97% of recovered r...

journal_title：Cancer

authors： Kerr DJ,Willmott N,McKillop JH,Cummings J,Lewi HJ,McArdle CS

更新日期：1988-09-01 00:00:00