Colorectal carcinoma cell production of transforming growth factor beta decreases expression of endothelial cell vascular endothelial growth factor receptor 2.

abstract：:Lobular carcinoma may arise within the epithelial component of fibroadenoma of the breast, as evidenced by 5 cases reported from the files of the Mayo Clinic and 21 cases cited in the literature. The 5 cases reported here occurred in a series of 4000 cases of fibroadenoma during a 43-year period. Lobular carcinoma is ...

journal_title：Cancer

authors： Buzanowski-Konakry K,Harrison EG Jr,Payne WS

更新日期：1975-02-01 00:00:00

abstract：:A case of fatal acute hepatic vein thrombosis occurred during treatment for Hodgkin's disease. At necropsy no evidence of Hodgkin's disease or obliterative venoocclusive disease of the liver was found. We speculate that Adriamycin, DTIC and/or vinblastine may have been responsible for this unusual disorder. ...

journal_title：Cancer

authors： Houghton AN,Shafi N,Rickles FR

更新日期：1979-12-01 00:00:00

abstract：BACKGROUND:To propose 'never-smoking nonsmall cell lung cancer (NSCLC)' as a separate entity, the clinicopathologic differences of operable NSCLC between never-smoking patients and patients with a history of smoking were investigated. METHODS:The medical records of 1405 patients with primary NSCLC who underwent a comp...

journal_title：Cancer

authors： Yano T,Miura N,Takenaka T,Haro A,Okazaki H,Ohba T,Kouso H,Kometani T,Shoji F,Maehara Y

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Historically, patients with nonmetastatic renal cell carcinoma (RCC) involving adjacent organs have been considered inoperable and incurable. The oncologic efficacy of an aggressive surgical approach was evaluated in a selected subpopulation of RCC patients. Further, an attempt was made to define the clinica...

journal_title：Cancer

authors： Margulis V,Sánchez-Ortiz RF,Tamboli P,Cohen DD,Swanson DA,Wood CG

更新日期：2007-05-15 00:00:00

abstract：:Fifty-three patients with advanced lymphocytic lymphoma were randomly assigned to treatment with the combination cyclophosphamide, vincristine, and prednisone (CVP) or the same agents used successively in maximal doses (C-V-P). Complete remissions occurred in 68% with CVP and 48% with C-V-P. For patients with nodular ...

journal_title：Cancer

authors： Kennedy BJ,Bloomfield CD,Kiang DT,Vosika G,Peterson BA,Theologides A

更新日期：1978-01-01 00:00:00

abstract：:Eighty-one primary ovarian carcinoids and intraovarian metastases from six mid-gut carcinoids were examined for the presence of tumor cells immunoreactive with antisera raised against various neurohormonal peptides, mostly of gastroenteropancreatic (GEP) origin. Twenty of the primary and two of the metastatic carcinoi...

journal_title：Cancer

authors： Sporrong B,Falkmer S,Robboy SJ,Alumets J,Håkanson R,Ljungberg O,Sundler F

更新日期：1982-01-01 00:00:00

abstract：:Venous thromboembolism (VTE) is a frequent complication of cancer and cancer treatment and is associated with multiple clinical consequences, including recurrent VTE, bleeding, and an increase in the risk of death. Although the risks associated with VTE have been well recognized in surgical cancer patients, there is a...

journal_title：Cancer

authors： Lyman GH

更新日期：2009-12-15 00:00:00

abstract：BACKGROUND:Fine-needle aspiration biopsy (FNAB) has been used with variable success as a diagnostic test for benign and malignant breast lesions. The goal of this study was to examine the effects of training physicians in the fine-needle aspiration sampling-technique on the diagnostic accuracy of FNAB of palpable breas...

journal_title：Cancer

authors： Ljung BM,Drejet A,Chiampi N,Jeffrey J,Goodson WH 3rd,Chew K,Moore DH 2nd,Miller TR

更新日期：2001-08-25 00:00:00

abstract：BACKGROUND:The balance among cell proliferation, cell differentiation, and cell death determines the cell number in a population as well as the size or even the stage of a tumor. Thus, to improve our understanding of the pathogenesis of neoplasms, it is important to investigate the regulation of both cell proliferation...

journal_title：Cancer

authors： Shen KL,Harn HJ,Ho LI,Yu CP,Chiu SC,Lee WH

更新日期：1998-06-15 00:00:00

abstract：BACKGROUND:Antithymocyte globulin (ATG) is an important component of conditioning regimens to prevent severe graft-versus-host disease (GVHD) in patients undergoing unmanipulated, haploidentical stem cell transplantation (haplo-SCT). However, to the authors' knowledge, the optimal dose of ATG is unknown. METHODS:In th...

journal_title：Cancer

authors： Chang YJ,Wang Y,Mo XD,Zhang XH,Xu LP,Yan CH,Chen H,Chen YH,Chen Y,Han W,Wang FR,Wang JZ,Liu KY,Huang XJ

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:The value of ultrasound-guided fine-needle aspiration cytology (FNAC) in the diagnosis of nonpalpable breast lesions remains a subject of debate. To determine the accuracy of this procedure in these lesions, a comparative analysis with open surgical biopsy in 188 patients was performed. METHODS:Six hundred ...

journal_title：Cancer

authors： Klijanienko J,Côté JF,Thibault F,Zafrani B,Meunier M,Clough K,Asselain B,Vielh P

更新日期：1998-02-25 00:00:00

abstract：BACKGROUND:Cognitive dysfunction experienced by individuals with cancer represents an important survivorship issue because of its potential to affect occupational, scholastic, and social activities. Whereas early efforts to characterize cognitive dysfunction primarily focused on the effects of chemotherapy, more recent...

journal_title：Cancer

authors： Wefel JS,Vidrine DJ,Veramonti TL,Meyers CA,Marani SK,Hoekstra HJ,Hoekstra-Weebers JE,Shahani L,Gritz ER

更新日期：2011-01-01 00:00:00

abstract：:The authors studied the expression of c-myc and ras family oncogene products in 43 cases of malignant lymphoma (ML) using the immunoperoxidase method. Unfixed frozen sections of lymph nodes from four patients with Hodgkin's disease and 39 with non-Hodgkin's lymphoma, together with normal lymph nodes, were studied by t...

journal_title：Cancer

authors： Mitani S,Sugawara I,Shiku H,Mori S

更新日期：1988-11-15 00:00:00

abstract：:Fourteen patients with 16 metastatic ostogenic sarcoma lesions were treated with high-dose methotrexate (HDMTX) with citrovorum factor rescue (CFR), adriamycin, and pulse high-dose cyclophosphamide combined with radiation therapy. Thirteen of 16 lesions responded. Responses consisted of relief of pain (6/6 patients) i...

journal_title：Cancer

authors： Rosen G,Tefft M,Martinez A,Cham W,Murphy ML

更新日期：1975-03-01 00:00:00

abstract：:The American Joint Committee on Cancer proposes the following criteria for evaluating putative prognostic factors: they must be (1) significant, (2) independent, and (3) clinically important. Furthermore, we suggest the criteria for selecting a prognostic system that includes TNM and new prognostic factors. These crit...

journal_title：Cancer

authors： Burke HB,Henson DE

更新日期：1993-11-15 00:00:00

abstract：BACKGROUND:Clips are often placed to mark axillary nodes with biopsy-confirmed metastases in patients with breast cancer. The evaluation of clipped nodes after chemotherapy can identify patients who have eradication of nodal disease. The goal of this study was to determine whether preoperative fine-needle aspiration (F...

journal_title：Cancer

authors： Caudle AS,Kuerer HM,Krishnamurthy S,Shin K,Hobbs BP,Ma J,Mittendorf EA,Washington AC,DeSnyder SM,Black DM,Hunt KK,Yang WT

更新日期：2019-02-01 00:00:00

abstract：:Alkylating agents form the basis of most combination treatment regimens for low-grade lymphoproliferative disorders. Bendamustine is a unique alkylating agent that has distinctive preclinical activity in cell lines resistant to other alkylators. Furthermore, clinical activity has been demonstrated in patients with alk...

journal_title：Cancer

authors： Kalaycio M

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:The clinical value of DNA flow cytometry of colorectal cancer is unclear. The purpose of this retrospective study was to evaluate the relationship between tumor flow cytometry, histopathologic parameters, and survival. METHODS:Flow cytometry was performed on paraffin embedded specimens from 653 patients who...

journal_title：Cancer

authors： Tang R,Ho YS,You YT,Hsu KC,Chen JS,Changchien CR,Wang JY

更新日期：1995-11-15 00:00:00

abstract：:The introduction of trimodal combination therapy (surgery + radiation + intraarterial infusion) for maxillary carcinoma resulted in a change in the sites of recurrence and no satisfactory improvement in the local control rate. To examine the cause of these phenomena, external carotid angiography was performed on 51 pa...

journal_title：Cancer

authors： Shibuya H,Suzuki S,Horiuchi J,Takagi M,Okuyama T,Suzuki H,Takeda M

更新日期：1982-12-15 00:00:00

abstract：:The clinicopathologic features and response to therapy of 28 patients with non-Ewing's flat bone sarcoma treated at St. Jude Children's Research Hospital, Memphis, Tennessee, over a 25-year period were reviewed. Twenty-two patients had osteosarcoma, four malignant fibrous histiocytoma, one chondrosarcoma, and one fibr...

journal_title：Cancer

authors： Kellie SJ,Pratt CB,Parham DM,Fleming ID,Meyer WH,Rao BN

更新日期：1990-02-15 00:00:00

abstract：:In 95 surgically staged patients with squamous cell carcinoma of the maxillary sinus, multivariate regression analyses were employed to identify prognostic factors. Possible prognostic factors for local control were TNM stage and type of surgical procedures: T2 or T3 tumors and use of total maxillectomy showed better ...

journal_title：Cancer

authors： Kondo M,Ogawa K,Inuyama Y,Yamashita S,Tominaga S,Shigematsu N,Nishiguchi I,Hashimoto S

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:The appearance of p53 mutations in colorectal carcinoma was determined, independent of differentiation and tumor stage of the primary tumors, in relation to the survival of patients who were scheduled to undergo liver resection. METHODS:Tumor material was analyzed for p53 mutations in primary colorectal tum...

journal_title：Cancer

authors： Yang Y,Forslund A,Remotti H,Lönnroth C,Andersson M,Brevinge H,Svanberg E,Lindnér P,Hafström L,Naredi P,Lundholm K

更新日期：2001-02-15 00:00:00

abstract：BACKGROUND:Recent studies have shown that multiple cytokines are secreted by ovarian epithelial cancer cells. Previous studies have shown that the cancer cell lines secrete macrophage colony-stimulating factor (M-CSF), granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-1 (IL-1), interleukin-6 (IL-6)...

journal_title：Cancer

authors： Moradi MM,Carson LF,Weinberg B,Haney AF,Twiggs LB,Ramakrishnan S

更新日期：1993-10-15 00:00:00

abstract：BACKGROUND:The objective of this study was to establish the incidence and risk factors for the development of second solid cancers after allogeneic hematopoietic stem cell transplantation (allo-HSCT). METHODS:The authors reviewed the case files of 926 consecutive patients who underwent allo-HSCT at their institution b...

journal_title：Cancer

authors： Gallagher G,Forrest DL

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:The effect on prognosis of adding imatinib mesylate to the treatment of patients with Philadelphia chromosome (Ph)-positive chronic myelogenous leukemia (CML) has not been explored fully. The objective of the current study was to evaluate the benefit of adding imatinib to the treatment sequence of patients w...

journal_title：Cancer

authors： Kantarjian H,O'Brien S,Cortes J,Shan J,Giles F,Garcia-Manero G,Verstovsek S,Faderl S,Rios MB,Talpaz M

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:It is believed that atypical cells identified by nipple duct lavage (NDL) indicate an increased risk for breast carcinoma similar to atypical ductal hyperplasia diagnosed by tissue biopsy, but many basic performance characteristics of NDL currently are undefined. METHODS:NDL was performed in 108 patients un...

journal_title：Cancer

authors： Johnson-Maddux A,Ashfaq R,Cler L,Naftalis E,Leitch AM,Hoover S,Euhus DM

更新日期：2005-03-15 00:00:00

abstract：:The cancer experience among 754 first-degree relatives (mothers, fathers, and siblings) of a population-based series of 177 children with soft tissue sarcoma is reported. The current study represents an extension of our earlier work in which the authors found an excess of breast cancer in the mothers of 143 of these c...

journal_title：Cancer

authors： Birch JM,Hartley AL,Blair V,Kelsey AM,Harris M,Teare MD,Jones PH

更新日期：1990-11-15 00:00:00

abstract：:Between 1957 and February 1981, 782 patients received cytotoxic chemotherapy for gestational trophoblastic tumors (GTT) in the Department of Medical Oncology, Charing Cross Hospital (London, England). Sixty-nine (8.8%) patients had central nervous system (CNS) metastases. Thirty-three of them (48%) presented with CNS ...

journal_title：Cancer

authors： Athanassiou A,Begent RH,Newlands ES,Parker D,Rustin GJ,Bagshawe KD

更新日期：1983-11-01 00:00:00

abstract：:Seven adults had a distinct clinicopathologic type of lymphoproliferative disorder of the bone marrow. All patients presented with weakness and pancytopenia; no evidence of gross extramedullary involvement was found. In 5 cases severe and prolonged bone marrow hypoplasia was associated with combination chemotherapy; 1...

journal_title：Cancer

authors： Barton JC,Conrad ME,Vogler LB,Parmley RT

更新日期：1980-10-15 00:00:00

abstract：:The physician must suspect pancreatic cancer in patients older than age 40 years who present with minimal vague symptoms. The presence of common disorders such as gallstones, hiatal hernia and diverticulosis coli, does not exclude pancreatic cancer. Ultrasonography, computed tomography, ERCP and cytology are the essen...

journal_title：Cancer

authors： Moossa AR

更新日期：1982-12-01 00:00:00