Pathologic findings from the National Surgical Adjuvant Breast Project. VIII. Relationship of chemotherapeutic responsiveness to tumor differentiation.

abstract：:A patient is described with chronic myelogenous leukemia (CML) and an unusual karyotype 46XY,t(Y;12) (q11;p12), whose clinical course was complicated by T-cell lymphoma 5 years later. At that time bone marrow cells showed an additional karyotypic abnormality 46XY,t(Y;12) (q11;p12) del(7) (pter-p21), which remained unc...

journal_title：Cancer

authors： Blonk MC,van der Valk P,Beverstock GC,Ossenkoppele GJ

更新日期：1990-09-15 00:00:00

abstract：BACKGROUND:Factors that could optimize the management of pediatric spinal cord astrocytoma remain unclear and controversial. METHODS:To determine the factors that influence the prognosis of pediatric patients with spinal cord astrocytomas, a series of 73 consecutive patients at 13 French treatment centers with histolo...

journal_title：Cancer

authors： Bouffet E,Pierre-Kahn A,Marchal JC,Jouvet A,Kalifa C,Choux M,Dhellemmes P,Guérin J,Tremoulet M,Mottolese C

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:Patient navigation programs are emerging that aim to address disparities in clinical trial participation among medically underserved populations, including racial/ethnic minorities. However, there is a lack of consensus on the role of patient navigators within the clinical trial process as well as outcome me...

journal_title：Cancer

authors： Ghebre RG,Jones LA,Wenzel JA,Martin MY,Durant RW,Ford JG

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Only five cases of basaloid squamous cell carcinoma (BSCC), a rare tumor of head and neck, have been reported to involve the floor of mouth. METHODS:Clinicopathologic and immunohistochemical features of eight BSCC of floor of mouth were studied to evaluate the significance of the basaloid features. RESULTS...

journal_title：Cancer

authors： Coppola D,Catalano E,Tang CK,Elfenbein IB,Harwick R,Mohr R

更新日期：1993-10-15 00:00:00

abstract：BACKGROUND:Hereditary nonpolyposis colorectal cancer (HNPCC or Lynch syndrome) is an autosomal dominant disease characterized by early-onset intestinal neoplasms, localization of tumors in the proximal colon, and frequent association with cancers at other sites, especially the endometrium, skin, and stomach. The identi...

journal_title：Cancer

authors： Ponz de Leon M,Sassatelli R,Benatti P,Roncucci L

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:The aims of this study were to compare human epidermal growth factor receptor 2 (HER2) results between immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH), and to investigate the clinicopathological characteristics and outcomes according to their results. METHODS:Using consecutive tissu...

journal_title：Cancer

authors： Park S,Park HS,Koo JS,Yang WI,Kim SI,Park BW

更新日期：2012-02-15 00:00:00

abstract：BACKGROUND:The authors administered a combination of docetaxel and topotecan with granulocyte-colony-stimulating factor (G-CSF) support in a Phase I study to define the maximum tolerated dose (MTD) of this regimen. METHODS:Patients with advanced-stage solid tumors were eligible for this trial if they had a Zubrod perf...

journal_title：Cancer

authors： Tsao AS,Shin DM,Palmer JL,Lee JS,Glisson BS

更新日期：2004-05-15 00:00:00

abstract：BACKGROUND:The presence of urinary excretion products of human chorionic gonadotropin (hCG) has been proposed as a tumor marker. To ascertain the clinical value in gynecologic cancers, the authors studied 612 nonpregnant women. METHODS:Three different assays in four clinical groups were compared: no disease, benign di...

journal_title：Cancer

authors： Neven P,Iles RK,Lee CL,Hudson CN,Shepherd JH,Chard T

更新日期：1993-06-15 00:00:00

abstract：:The case history of a woman with a "female adnexal tumor of probable Wolffian origin" is described in which the neoplasm recurred three times during a 16-year interval and responded with prolonged remission after repeated surgical excision and radiotherapy. Ultrastructural data are given to support the Wolffian nature...

journal_title：Cancer

authors： Brescia RJ,Cardoso de Almeida PC,Fuller AF Jr,Dickersin GR,Robboy SJ

更新日期：1985-09-15 00:00:00

abstract：:Between June 1977 and December 1978, occult testicular leukemia (OTL) was discovered at three years of continual complete remission (CCR) from the time of diagnosis of acute lymphoblastic leukemia (ALL) in 5 of 59 (8.5%) of males undergoing bilateral wedge testicular biopsy at 1 of 15 participating Southwest Oncology ...

journal_title：Cancer

authors： Askin FB,Land VJ,Sullivan MP,Ragab AH,Steuber CP,Dyment PG,Talbert J,Moore T

更新日期：1981-02-01 00:00:00

abstract：:A case of an acute myocardial infarction occurring in a 19-year-old woman, 27 months after mantle radiotherapy for Stage II-A Hodgkin's disease is described. The coronary arteriogram demonstrated patent and normal coronary arteries, but the echocardiogram revealed pericarditis. The clinical course was further complica...

journal_title：Cancer

authors： Yahalom J,Hasin Y,Fuks Z

更新日期：1983-08-15 00:00:00

abstract：:Bleomycin (BLM)-inactivating enzyme activity, which is probably a parameter for the efficacy of this antibiotic in cancer therapy, was determined in biopsies from human carcinomas in the head and neck region. Twenty-three cases were studied. It was found that highly differentiated as well as moderately differentiated ...

journal_title：Cancer

authors： Müller WE,Schmidseder R,Rohde HJ,Zahn RK,Scheunemann H

更新日期：1977-12-01 00:00:00

abstract：:Adenoid cystic carcinoma of the esophagus is a relatively rare lesion which characteristically exhibits a clinically aggressive behavior. In spite of this aggressive nature, it is most often referred to as a counterpart of the more common adenoid cystic carcinoma of salivary gland origin, a comparatively indolent tumo...

journal_title：Cancer

authors： Epstein JI,Sears DL,Tucker RS,Eagan JW Jr

更新日期：1984-03-01 00:00:00

abstract：:In a retrospective review (1950-1975) of the Mayo Clinic experience with seminomas (483 cases), twelve patients (2.5%) were found to have a retroperitoneal seminoma without evidence of testicular involvement. The mean age was 47 years (range, 31-67). Eleven patients were treated by radiation alone, with doses ranging ...

journal_title：Cancer

authors： Buskirk SJ,Evans RG,Farrow GM,Earle JD

更新日期：1982-05-01 00:00:00

abstract：:Eighteen patients with unresectable ductal adenocarcinoma of the pancreas received definitive, high-dose, small-volume radiation therapy. All patients had at least one laparotomy, at which time a biopsy was obtained, radio-opaque clips were placed to define the extent of the gross tumor, and usually some form of bypas...

journal_title：Cancer

authors： Dobelbower RR Jr,Borgelt BB,Suntharalingam N,Strubler KA

更新日期：1978-03-01 00:00:00

abstract：BACKGROUND:Transitional cell carcinoma (TCC) of the bladder displays an unpredictable biologic behavior and the morphologic methods of grading tumor malignancy are often insufficient to predict the clinical outcome of patients with TCC of the bladder. Thus, the new indicator should reliably reflect prognosis. In this s...

journal_title：Cancer

authors： Shiina H,Igawa M,Nagami H,Yagi H,Urakami S,Yoneda T,Shirakawa H,Ishibe T,Kawanishi M

更新日期：1996-10-15 00:00:00

abstract：:Late side effects of chemotherapy were studied in 51 women who had received at least 300 mg of melphalan for ovarian cancer and had survived for at least three years. Hematologic, statistical, and cytogenetic methods were employed. Six cases of iatrogenic leukemia were found. They appeared to represent a hematologic e...

journal_title：Cancer

authors： Einhorn N,Eklund G,Franzén S,Lambert B,Lindsten J,Söderhäll S

更新日期：1982-06-01 00:00:00

abstract：:An unusual thyroid carcinoma is described, showing structural, histochemical and radioimmunologic features of both a follicular and a parafollicular cell carcinoma. Radioimmunoassay revealed high levels of thyroglobulin in the patient's serum and in extracts from metastatic tumor tissue. Immunoreactive thyroglobulin w...

journal_title：Cancer

authors： Ljungberg O,Ericsson UB,Bondeson L,Thorell J

更新日期：1983-09-15 00:00:00

abstract：:The evidence that various endogenous and exogenous sex hormones play a role in the etiology of breast cancer is reviewed. It is hypothesized that prolonged exposure to normal levels of ovarian estrogens and cyclic progesterone resulting from early menarche and late menopause, and primarily willful nulliparity and late...

journal_title：Cancer

authors： Thomas DB

更新日期：1984-02-01 00:00:00

abstract：:A humoral microcytotoxicity assay has been used to study the immune response to human malignant astrocytic tumors. Two series are described. When the assay was performed under uniform, ideal conditions, the sera from 36 of 45 patients with these tumors (80%) produced significant cytotoxicity against allogeneic astrocy...

journal_title：Cancer

authors： Wood WC,Kornblith PL,Quindlen EA,Pollock LA

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND:Childhood cancer survivors have been reported to be vulnerable to psychiatric morbidities and risky health behavior. Suicides, substance abuse, accidents, and violence as causes of death can be regarded as an extreme manifestation of risky health behavior. In the current study, the authors studied the risk o...

journal_title：Cancer

authors： Korhonen LM,Taskinen M,Rantanen M,Erdmann F,Winther JF,Bautz A,Feychting M,Mogensen H,Talbäck M,Malila N,Ryynänen H,Madanat-Harjuoja L

更新日期：2019-10-15 00:00:00

abstract：BACKGROUND:The usefulness of fine-needle aspiration biopsy (FNAB) for the histologic subtyping of specific sarcomas still is somewhat controversial but is becoming increasingly popular in the U.S. METHODS:To determine the accuracy and usefulness of FNAB in the differential diagnosis of myxoid sarcoma, the authors retr...

journal_title：Cancer

authors： Kilpatrick SE,Ward WG,Bos GD

更新日期：2000-06-25 00:00:00

abstract：:Serum complements, C3, C4, and C3 proactivator (C3PA), were evaluated prospectively for their diagnostic power in detecting hepatocellular carcinoma (HCC) in patients with liver cirrhosis (LC). Sixty-three LC patients, including 36 LC with HCC patients, were recruited for this study during the period from March to Nov...

journal_title：Cancer

authors： Chang WY,Chuang WL

更新日期：1988-07-15 00:00:00

abstract：:The individual medical histories in the files of the Oxford Record Linkage Study for the years 1963 to 1967 were analyzed to ascertain any previously unsuspected associations between cancers of the large bowel and other diseases in individuals, and to quantify the relative risks of disorders already known to be associ...

journal_title：Cancer

authors： Adelstein P,Baldwin JA,Fedrich J

更新日期：1979-06-01 00:00:00

abstract：BACKGROUND:Multidisciplinary management of head and neck cancer (HNC) must reconcile increasingly sophisticated subspecialty care with timeliness of care. Prior studies examined the individual effects of delays in diagnosis-to-treatment interval, postoperative interval, and radiation interval but did not consider them ...

journal_title：Cancer

authors： Ho AS,Kim S,Tighiouart M,Mita A,Scher KS,Epstein JB,Laury A,Prasad R,Ali N,Patio C,Clair JM,Zumsteg ZS

更新日期：2018-08-01 00:00:00

abstract：:Pel-Epstein fever cycles, consisting of 1-2 weeks of high fever separated by afebrile periods of the same duration, are classically characteristic of Hodgkin's disease. Clinical observation has determined that the lymph nodes enlarge during periods of fever and reduce in size as the fever subsides. To our knowledge, t...

journal_title：Cancer

authors： Scanlon GT,Castellino RA,Rudders R

更新日期：1975-12-01 00:00:00

abstract：BACKGROUND:There is no consistent definition at what age patients with non-Hodgkin lymphoma (NHL) are considered "elderly." This might hamper well balanced decisions with respect to treatment. METHODS:From a population-based NHL registry the age groups younger than 60 years, 60-64 years, 65-69 years, 70-74 years, and ...

journal_title：Cancer

authors： Maartense E,Kluin-Nelemans HC,le Cessie S,Kluin PM,Snijder S,Noordijk EM

更新日期：2000-12-15 00:00:00

abstract：BACKGROUND:Low frequency epithelial cells in bone marrow from colorectal carcinoma patients are associated with an increased risk of recurrence and decreased survival. Current immunohistochemical approaches to detect epithelial cells in bone marrow aspirates rely on antibodies against cytokeratin 18 (CK18). The predict...

journal_title：Cancer

authors： Litle VR,Warren RS,Moore D 2nd,Pallavicini MG

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:Second primary tumors are a leading cause of death among patients with head and neck cancer; therefore, early detection of these tumors is necessary. In the current study, the authors aimed to evaluate the diagnostic capacity of (18)F-fluorodeoxyglucose dual-head positron emission tomography (FDG-PET) for de...

journal_title：Cancer

authors： Stokkel MP,Moons KG,ten Broek FW,van Rijk PP,Hordijk GJ

更新日期：1999-12-01 00:00:00

abstract：:Cancer is among the leading causes of morbidity and mortality in the Western world. Despite recent advances, most therapeutic approaches fail to eradicate the entire neoplastic clone. The remaining cells often develop metastasis and/or recurrences and therefore may represent attractive targets of therapy. A new exciti...

journal_title：Cancer

authors： Schulenburg A,Ulrich-Pur H,Thurnher D,Erovic B,Florian S,Sperr WR,Kalhs P,Marian B,Wrba F,Zielinski CC,Valent P

更新日期：2006-11-15 00:00:00