Multimodality therapy in the management of angiosarcoma of the breast.

abstract：BACKGROUND:In addition to tumor thickness, several other prognostic parameters have been identified in primary human melanomas. Some are available readily (localization, gender, age, and ulceration). Others must be evaluated with a moderate or even substantial amount of work (mitoses and immunohistochemical markers). T...

journal_title：Cancer

authors： Ostmeier H,Fuchs B,Otto F,Mawick R,Lippold A,Krieg V,Suter L

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:Breast carcinoma commonly metastasizes to the skeleton in patients with advanced disease to cause bone destruction and the associated pain, hypercalcemia, fracture, and nerve-compression syndromes. In this scenario, the bone destruction is mediated by the osteoclast. Tumor-produced parathyroid hormone-relate...

journal_title：Cancer

authors： Guise TA

更新日期：2000-06-15 00:00:00

abstract：BACKGROUND:The Akt/mammalian target of rapamycin (mTOR) pathway mediates cell survival and proliferation and contributes to tumor progression. Soft tissue leiomyosarcoma continues to show poor prognosis, and little is known about its mechanisms of tumor progression. Here the authors investigated the significance of act...

journal_title：Cancer

authors： Setsu N,Yamamoto H,Kohashi K,Endo M,Matsuda S,Yokoyama R,Nishiyama K,Iwamoto Y,Dobashi Y,Oda Y

更新日期：2012-03-15 00:00:00

abstract：:This article reviews the clinicopathologic features and the biological behavior of 24 cases of synovial sarcoma that took origin from the cervical prevertebral connective tissue space and manifested as a retropharyngeal tumor or as a palpable mass in the anterior or posterior cervical triangle. The age of the 24 patie...

journal_title：Cancer

authors： Roth JA,Enzinger FM,Tannenbaum M

更新日期：1975-04-01 00:00:00

abstract：:The establishment of a cell culture system for the clonal development of hematopoietic cells has made it possible to discover the proteins that control growth and differentiation of different hematopoietic cell lineages and the molecular basis of normal and abnormal cell development in blood-forming tissues. A model s...

journal_title：Cancer

authors： Sachs L

更新日期：1990-05-15 00:00:00

abstract：:Giant sections from cystectomy specimens in 45 cases of bladder cancer were examined microscopically after en bloc fixation and processing. There were 35 transitional cell, seven squamous cell, and three mixed transitional cell and squamous carcinomas. Broad front invasion was associated with papillary and superficial...

journal_title：Cancer

authors： Soto EA,Friedell GH,Tiltman AJ

更新日期：1977-02-01 00:00:00

abstract：:A hybrid radiofrequency heating system previously reported to produce highly focused heating patterns at less than or equal to 10 cm depth in phantom models was utilized to selectively heat hypervascular, heat resistant rabbit V-2 tumors implanted in the left hindlimb. Spheroidal heating patterns 3 to 4 cm in diameter...

journal_title：Cancer

authors： Boddie AW Jr,Merritt DR,Yamanashi W,Frazer JW,McBride CM,Martin RG

更新日期：1985-03-15 00:00:00

abstract：:Twenty of 391 newly diagnosed cases of prostatic cancer (5%) had a prior prostatectomy for benign disease. Digital rectal examination in 16 of 19 patients (84%) revealed a significant prostatic abnormality. Continued serial digital rectal examination should be performed routinely after prostatectomy for benign disease...

journal_title：Cancer

authors： Schwartz I,Wein AJ,Malloy TR,Glick JH

更新日期：1986-08-15 00:00:00

abstract：BACKGROUND:Clear cell tumors of the thyroid gland in general are uncommon. Metastatic renal cell carcinoma (RCC) to the thyroid gland is a rare occurrence but must be considered in the differential diagnosis of a thyroid gland clear cell neoplasm to prevent misclassification, potentially resulting in inappropriate clin...

journal_title：Cancer

authors： Heffess CS,Wenig BM,Thompson LD

更新日期：2002-11-01 00:00:00

abstract：:A series of 27 typical Krukenberg tumors of the ovary were analyzed. By definition, all examples were characterized by the presence of mucinous signet-ring carcinoma cells within a cellular, nonneoplastic ovarian stroma. The patients' ages ranged from 20-70 years; almost one-half were 40 years of age or younger. A pri...

journal_title：Cancer

authors： Holtz F,Hart WR

更新日期：1982-12-01 00:00:00

abstract：:Ninety-two cases of granulosa cell tumor of the ovary have been studied. The clinical and pathologic data from this group were similar to that obtained in previous series. Because of the long natural history of many granulosa cell tumors, crude death rates over a relatively short period give little indication of the t...

journal_title：Cancer

authors： Fox H,Agrawal K,Langley FA

更新日期：1975-01-01 00:00:00

abstract：:C57B1/6 mice were given intravenous tumor cells on day O. Mice were then given either a brief exposure to halothane anesthesia or given halothane and then underwent a hind limb amputation. Immune testing was done at varying time intervals and correlated with the development of artificial pulmonary metastases. The effe...

journal_title：Cancer

authors： Lundy J,Lovett EJ 3rd,Hamilton S,Conran P

更新日期：1978-03-01 00:00:00

abstract：:The experience of 260 patients with endometrial carcinoma was reviewed. The influence of factors such as age, stage of disease, grade and degree of myometrial penetration on the survival was presented, showing that survival decreases in elderly patients, in patients with advanced stage of disease, when the tumor is un...

journal_title：Cancer

authors： Tavares MA,Patricio MB,Vilhena M,Da Silva JN

更新日期：1977-02-01 00:00:00

abstract：:One-hundred-eighty-eight children up to 16 years of age were randomized in the second National Wilms' Tumor Study (NWTS) with tumors that were confined to the kidney and that had been totally excised (Group I). Most fared well whether treated for six or for 15 months with both actinomycin D (AMD) and vincristine (VCR)...

journal_title：Cancer

authors： D'Angio GJ,Evans A,Breslow N,Beckwith B,Bishop H,Farewell V,Goodwin W,Leape L,Palmer N,Sinks L,Sutow W,Tefft M,Wolff J

更新日期：1981-05-01 00:00:00

abstract：BACKGROUND:Epithelioid hemangioendothelioma (EHE) is a rare neoplasm of vascular origin that occurs in the liver and other organs; its etiology is unknown. METHODS:The authors analyzed the clinicopathologic and immunohistochemical features of 137 patients with EHE of the liver in an attempt to identify features that m...

journal_title：Cancer

authors： Makhlouf HR,Ishak KG,Goodman ZD

更新日期：1999-02-01 00:00:00

abstract：:A previously unreported high incidence of endoscopically identifiable, diffuse, largely nonulcerative esophagitis, is described in a selected population of Southern African blacks at risk of cancer of the esophagus. This is comparable with findings in similar groups in Iran and China. The incidence of dysplasia and "e...

journal_title：Cancer

authors： Oettlé GJ,Paterson AC,Leiman G,Segal I

更新日期：1986-06-01 00:00:00

abstract：BACKGROUND:Diagnosis of nasopharyngeal carcinoma (NPC) at an early disease stage is important for successful treatment and improving the outcome of patients. The use of serum protein profiles and a classification tree algorithm were explored to distinguish NPC from noncancer. METHODS:Serum samples were applied to meta...

journal_title：Cancer

authors： Ho DW,Yang ZF,Wong BY,Kwong DL,Sham JS,Wei WI,Yuen AP

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Cytologic distinction between follicle center lymphoma (FCL) and mantle cell lymphoma (MCL) is difficult with cytomorphology alone and requires immunophenotyping. The current study describes the distinction between follicle center and mantle cell lymphoma made with fine-needle aspiration (FNA) material. MET...

journal_title：Cancer

authors： Rassidakis GZ,Tani E,Svedmyr E,Porwit A,Skoog L

更新日期：1999-08-25 00:00:00

abstract：:While investigating the cause of mild polycythemia in a young man, a testicular seminoma was discovered with unusual and tumor-dependent features: an absolute polycythemia with high plasma erythropoietin (EPO) levels, an overproduction of estradiol and testosterone, and a dramatic Leydig cell hyperplasia surrounding t...

journal_title：Cancer

authors： Reman O,Reznik Y,Casadevall N,Lacombe C,Troussard X,Mandard JC,Leporrier M,Mahoudeau J

更新日期：1991-11-15 00:00:00

abstract：:The cancer experience among 754 first-degree relatives (mothers, fathers, and siblings) of a population-based series of 177 children with soft tissue sarcoma is reported. The current study represents an extension of our earlier work in which the authors found an excess of breast cancer in the mothers of 143 of these c...

journal_title：Cancer

authors： Birch JM,Hartley AL,Blair V,Kelsey AM,Harris M,Teare MD,Jones PH

更新日期：1990-11-15 00:00:00

abstract：BACKGROUND:This study assessed the impact of surgical, histopathologic and patient-related factors on the risks of local and distant recurrence and overall survival for patients with stages I through IIIA nonsmall cell lung carcinoma (NSCLC) undergoing definitive resection with or without adjuvant chemotherapy. METHOD...

journal_title：Cancer

authors： Varlotto JM,Recht A,Flickinger JC,Medford-Davis LN,Dyer AM,Decamp MM

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Despite the widespread use of oxaliplatin-based regimens for colorectal and other gastrointestinal cancers, there is surprisingly little information regarding their empiric use for the treatment of carcinoma of unknown primary site (CUP). In the current study, the combination of oxaliplatin and capecitabine ...

journal_title：Cancer

authors： Hainsworth JD,Spigel DR,Burris HA 3rd,Shipley D,Farley C,Macias-Perez IM,Barton J,Greco FA

更新日期：2010-05-15 00:00:00

abstract：BACKGROUND:A somatic gain-of-function mutation of the Janus kinase 2 (JAK2) gene has been identified in chronic myeloproliferative disorders, which appear to have a sporadic occurrence in most individuals. The authors studied the biologic significance of the JAK2 (V617F) mutation in familial myeloproliferative disorder...

journal_title：Cancer

authors： Rumi E,Passamonti F,Pietra D,Della Porta MG,Arcaini L,Boggi S,Elena C,Boveri E,Pascutto C,Lazzarino M,Cazzola M

更新日期：2006-11-01 00:00:00

abstract：:Twenty-two cases of breast tumor with infiltrating lobular carcinoma were studied. Thirteen showed the classic single-file pattern as a sole component, and 6 as a predominant pattern; the less common confluent pattern was found in 3 instances as a predominant component. Mucin secretion was evidenced in 59% of the prim...

journal_title：Cancer

authors： Van Bogaert LJ,Maldague P

更新日期：1980-03-01 00:00:00

abstract：:Trabecular carcinoma of the skin (Merkel cell tumor), a neoplasm of putative neural origin, must be differentiated from other small cell tumors primary or metastatic to skin. In order to provide more objective diagnostic criteria, four were examined using monoclonal antibodies against neurofilament proteins (NF) and a...

journal_title：Cancer

authors： Leff EL,Brooks JS,Trojanowski JQ

更新日期：1985-08-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to identify biologic differences between ovarian clear cell carcinoma and other ovarian adenocarcinomas by comparing the expression of cell cycle regulatory molecules and by analyzing the survival of the patients. METHODS:In 51 cases of epithelial ovarian carcinoma, the express...

journal_title：Cancer

authors： Shimizu M,Nikaido T,Toki T,Shiozawa T,Fujii S

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:It is unclear whether patients with Stage II colon carcinoma should be offered adjuvant chemotherapy. Therefore, the authors analyzed the risk factors of these patients to identify high-risk subgroups who may benefit from such treatment. METHODS:The data from 305 patients with Stage II colon carcinoma docum...

journal_title：Cancer

authors： Merkel S,Wein A,Günther K,Papadopoulos T,Hohenberger W,Hermanek P

更新日期：2001-09-15 00:00:00

abstract：:The care of patients with cancer and chronic pain, often complicated and demanding, strains the resources of a single physician. Continuity of care programs, such as that developed by the Pain Service of Memorial Sloan-Kettering Cancer Center (New York), with good communication and liaison work between hospital and co...

journal_title：Cancer

authors： Coyle N

更新日期：1989-06-01 00:00:00

abstract：:The clonal growth pattern of bone marrow and peripheral blood cells from 16 patients with clinically suspected chronic myelogenous leukemia (CML) was evaluated in the double-layer agar system. Cytogenetic studies were performed on parallel marrow and peripheral blood samples. In four cases a unique growth pattern emer...

journal_title：Cancer

authors： Selvaggi S,Wolman SR,Bornstein S,Edinger F

更新日期：1984-12-15 00:00:00

abstract：:This report is to make the general scientific community aware of availability of human tissues through this network. During the short period of its existence, this network has developed useful procedures for distributing human tumor tissue in a rapid, scientifically useful, cost-effective manner to investigators to wh...

journal_title：Cancer

authors： Clausen KP,Grizzle WE,Livolsi V,Newton WA Jr,Aamodt R

更新日期：1989-04-01 00:00:00