Can immunohistochemical markers and mitotic rate improve prognostic precision in patients with primary melanoma?

abstract：:The results of trials testing combined surgery and chemotherapy in lung cancer are reviewed. Fifteen adjuvant trials using various chemotherapeutic agents were analyzed to determine reasons for their lack of success. Current trials with adjuvant therapy in lung cancer are briefly outlined. In addition, analysis of the...

journal_title：Cancer

authors： Legha SS,Muggia FM,Carter SK

更新日期：1977-04-01 00:00:00

abstract：BACKGROUND:A hypothesis generated a retrospective analysis of the improvement of survival over time in patients with cutaneous melanoma (CM) in order to identify factors contributing to this progress. METHODS:A cohort of 4791 patients diagnosed with primary CM in southern Germany between 1976 and 2001 was analyzed. Ka...

journal_title：Cancer

authors： Lasithiotakis KG,Leiter U,Eigentler T,Breuninger H,Metzler G,Meier F,Garbe C

更新日期：2007-03-15 00:00:00

abstract：:Although improvements in the management of adults with acute leukemia have lagged behind those seen in the treatment of children, there are clear reasons for optimism. Combination chemotherapy for acute myeloblastic leukemia (AML) and acute lymphoblastic leukemia (ALL) in adults results in complete remissions in 50-85...

journal_title：Cancer

authors： Eyre HJ,Ward JH,Priebat DA

更新日期：1983-06-15 00:00:00

abstract：:Univariate and multivariate regression methods were used to analyze 17 potential clinical prognostic factors among 138 patients with advanced breast cancer who received Adriamycin-cyclophosphamide combination chemotherapy between 1973 and 1977 at the University of Arizona. Follow-up of patients was through September 1...

journal_title：Cancer

authors： Nash CH 3rd,Jones SE,Moon TE,Davis SL,Salmon SE

更新日期：1980-12-01 00:00:00

abstract：:Three-hundred whole thyroid glands were collected at autopsy from patients who had no known clinical history of thyroid disease, and who varied from 13 to 82 years of age; 200 were male and 100 female. Thyroid glands were weighed, measured, and examined after previous formalin fixation. Histologic examination was done...

journal_title：Cancer

authors： Bisi H,Fernandes VS,de Camargo RY,Koch L,Abdo AH,de Brito T

更新日期：1989-11-01 00:00:00

abstract：:Thyroid function and scans were evaluated in fifty disease-free patients 2 to 16 years after receiving neck irradiation for the treatment of Hodgkin's disease. Twenty-five of 50 patients had abnormal thyroid studies: eight were hypothyroid, two were hypothyroid and had abnormal scans, and fifteen had abnormal scans. O...

journal_title：Cancer

authors： Nelson DF,Reddy KV,O'Mara RE,Rubin P

更新日期：1978-12-01 00:00:00

abstract：:A series of nine cases of radiation myelopathy seen at the University of California, San Francisco (UCSF) is reviewed, and their treatment data converted into nominal single doses (NSD) and equivalent single doses (ED). The 1% incidence level of myelopathy in the thoracic cord is 1015 rets (ED), and the 50% incidence...

journal_title：Cancer

authors： Wara WM,Phillips TL,Sheline GE,Schwade JG

更新日期：1975-06-01 00:00:00

abstract：INTRODUCTION:The presence of nodal metastases remains the most significant predictive factor for regional recurrence and survival in patients treated for squamous cell carcinoma of the head and neck. Survival rates are further decreased in patients with nodal metastases that have spread beyond the lymph node capsule, o...

journal_title：Cancer

authors： Myers JN,Greenberg JS,Mo V,Roberts D

更新日期：2001-12-15 00:00:00

abstract：BACKGROUND:Disruption of the lymphatic circulation through breast carcinoma-associated axillary lymph node dissection, with or without radiation therapy, reportedly is the most common cause of lymphedema in developed countries. There is no cure for breast carcinoma-associated lymphedema. Although intermittent pneumatic...

journal_title：Cancer

authors： Szuba A,Achalu R,Rockson SG

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:Caveolin-1 plays a regulatory role in several signaling pathways. Recently caveolin-1 was identified as a metastasis-related gene in prostate carcinoma. However, the clinical impact of caveolin-1 expression in esophageal carcinoma remains unknown. METHODS:One hundred thirty surgical specimens of esophageal ...

journal_title：Cancer

authors： Kato K,Hida Y,Miyamoto M,Hashida H,Shinohara T,Itoh T,Okushiba S,Kondo S,Katoh H

更新日期：2002-02-15 00:00:00

abstract：:An 11-year-old female with a large embryonal carcinoma of the left ovary was treated by unilateral salpingo-oophorectomy combined with a systemic chemotherapy of a total dose of 1.9 mg of dactinomycin. The preoperative serum alpha-fetoprotein (AFP) level of 70,350 ng/ml decreased to 270 ng/ml 5 weeks after the operati...

journal_title：Cancer

authors： Nakakuma K,Tashiro S,Uemura K,Takayama K

更新日期：1983-10-15 00:00:00

abstract：BACKGROUND:To assess whether the effectiveness of a combination of transcatheter arterial chemoembolization (TACE) and percutaneous ethanol injection (PEI) is superior to PEI alone in the treatment of patients with small hepatocellular carcinoma (HCC), a randomized controlled study was performed. METHODS:Fifty-two pat...

journal_title：Cancer

authors： Koda M,Murawaki Y,Mitsuda A,Oyama K,Okamoto K,Idobe Y,Suou T,Kawasaki H

更新日期：2001-09-15 00:00:00

abstract：BACKGROUND:The demonstration of the monoclonality of immunoglobulin heavy chain (IgH) gene rearrangement is an indispensable method for the diagnosis of B-cell lymphoma as well as histocytochemical analysis. For the detection of IgH gene rearrangement, the extraction of DNA from a homogenous cell population is necessar...

journal_title：Cancer

authors： Orba Y,Tanaka S,Nishihara H,Kawamura N,Itoh T,Shimizu M,Sawa H,Nagashima K

更新日期：2003-08-25 00:00:00

abstract：BACKGROUND:For this report, the authors comprehensively summarized the existing literature on patients with pineoblastoma and identified the variables and treatments that had an impact patient on outcomes. METHODS:A comprehensive search identified 109 studies that collectively described the outcomes of patients with p...

journal_title：Cancer

authors： Tate M,Sughrue ME,Rutkowski MJ,Kane AJ,Aranda D,McClinton L,McClinton L,Barani IJ,Parsa AT

更新日期：2012-01-01 00:00:00

abstract：:A routine admission chest radiograph (CXR) in pediatric patients with cancer who are admitted to the hospital for fever and neutropenia has been advised because the signs and symptoms of pneumonia may be absent. The authors studied 131 consecutive patient admissions for fever and neutropenia to evaluate the diagnostic...

journal_title：Cancer

authors： Katz JA,Bash R,Rollins N,Cash J,Buchanan GR

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND:Glioblastoma multiforme (GBM) is the most prevalent and deadly brain tumor. A variety of germline and somatic, genetic and epigenetic alterations at 9p21.3, which encode CDKN2A/CDKN2B tumor suppressor genes, have been isolatedly reported to be associated with GBM risk and prognosis. METHODS:To obtain a comp...

journal_title：Cancer

authors： Feng J,Kim ST,Liu W,Kim JW,Zhang Z,Zhu Y,Berens M,Sun J,Xu J

更新日期：2012-01-01 00:00:00

abstract：:Twenty-two children with acute lymphocytic leukemia (ALL) who had relapsed while on therapy and for whom remissions were successfully reinduced were maintained with a combination of methotrexate, daunomycin, 6-mercaptopurine, prednisone, and vincristine (Djerassi-methotrexate with BOMB). The median duration of remissi...

journal_title：Cancer

authors： Kimball JC,Herson J,Sullivan MP

更新日期：1980-09-01 00:00:00

abstract：:Proficiency testing in cytopathology and in other disciplines should be based on firm statistical and scientific foundations, because test theory in general is a heavily statistical subject. Statistical considerations have demonstrated that the design of "short" proficiency tests in cytopathology, including the curren...

journal_title：Cancer

authors： Nagy GK,Naryshkin S

更新日期：2007-12-25 00:00:00

abstract：BACKGROUND:Fas-expressing cytotoxic T lymphocytes (CTLs) are important antitumor immune effector cells in patients with hepatocellular carcinoma (HCC). The role of transforming growth factor beta 1 (TGF-beta1) in modulating the expression of Fas by CTLs is not known in HCC. The objectives of this study were to characte...

journal_title：Cancer

authors： Yuen MF,Hughes RD,Heneghan MA,Langley PG,Norris S

更新日期：2001-10-15 00:00:00

abstract：BACKGROUND:The authors' goal was to characterize hospice enrollment and aggressiveness of care for pancreatic cancer patients at the end of life. METHODS:Surveillance, Epidemiology, and End Results and linked Medicare claims data (1992-2006) were used to identify patients with pancreatic cancer who had died (n = 22,81...

journal_title：Cancer

authors： Sheffield KM,Boyd CA,Benarroch-Gampel J,Kuo YF,Cooksley CD,Riall TS

更新日期：2011-11-01 00:00:00

abstract：:Since 1975, clinical studies have been carried out to determine whether radiation when combined with localized hyperthermia evokes improved tumor control compared to that achieved with radiation alone. Local tumor hyperthermia was achieved using radiofrequency inductive heating at 27.12 MHz. In bulky lesions (greater ...

journal_title：Cancer

authors： Kim JH,Hahn EW,Ahmed SA

更新日期：1982-08-01 00:00:00

abstract：:Postmenopausal patients with metastatic breast cancer were treated with medroxyprogesterone acetate (MPA) (Clinovir) in dosages between 500 and 1500 mg orally per day. The relation of MPA plasma concentrations and endocrine effects were studied in a longitudinal fashion. MPA exerted suppressive effects on the basal an...

journal_title：Cancer

authors： Blossey HC,Wander HE,Koebberling J,Nagel GA

更新日期：1984-09-15 00:00:00

abstract：BACKGROUND:The goal of this study was to compare health-related quality of life (HRQL) from diagnosis to 10 years postdiagnosis among breast cancer survivors (BCS) and women without cancer over the same period and to identify BCS subgroups exhibiting different HRQL trajectories. METHODS:Our analysis included 141 BCS a...

journal_title：Cancer

authors： Avis NE,Levine B,Goyal N,Crawford SL,Hess R,Colvin A,Bromberger JT,Greendale GA

更新日期：2020-05-15 00:00:00

abstract：:Adrenal cortical carcinoma is an uncommon neoplasm in children. Only a handful of congenital adrenal cortical carcinoma cases have been described. A newborn who had metastatic adrenal cortical carcinoma (skin metastases and cerebral lesions) is described. This patient underwent surgical resection of the right adrenal ...

journal_title：Cancer

authors： Saracco S,Abramowsky C,Taylor S,Silverman RA,Berman BW

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND:Rising health care costs have caused providers to question the benefit of regular follow-up after treatment for patients with early stage cutaneous melanoma. The authors hypothesized that routine reassessment and careful education of these patients would facilitate earlier diagnosis of a subsequent second pr...

journal_title：Cancer

authors： DiFronzo LA,Wanek LA,Morton DL

更新日期：2001-04-15 00:00:00

abstract：:Sixty patients with advanced prostatic carcinoma were treated with monthly subcutaneous injections of a depot formulation of goserelin, a luteinizing hormone-releasing hormone (LHRH) analogue (Zoladex, ICI Pharma, Destelbergen, Belgium). All patients were regularly evaluated with measurements of luteinizing hormone (L...

journal_title：Cancer

authors： Mahler C,Verhelst J,Chaban M,Denis L

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:Testing for oral high-risk human papillomavirus (HPV) DNA may be useful for identifying individuals at increased risk for HPV-driven oropharyngeal cancer (OPC). However, positivity for HPV DNA provides no information on the transforming potential of the infection. In contrast, the detection of high-risk HPV ...

journal_title：Cancer

authors： Rollo F,Pichi B,Benevolo M,Giuliani M,Latini A,Lorenzon L,Colafigli M,Frasca M,Pellini R,Cristaudo A,Donà MG

更新日期：2019-08-01 00:00:00

abstract：:Utah cancer mortality for the years 1950-1969 and morbidity for the years 1966-1970 are reported. Utah had 18% fewer cases of cancer than expected based on the Third National Cancer Survey, and 24% fewer cancer deaths than expected based on national mortality data. Cancer sites associated with cigarette smoking and al...

journal_title：Cancer

authors： Lyon JL,Gardner JW,Klauber MR,Smart CR

更新日期：1977-06-01 00:00:00

abstract：:Temporary neurologic abnormalities were detected in 9 of 60 patients undergoing treatment with high-dose methotrexate and citrovorum factor rescue (MTX-CF) for osteosarcoma. The incidence of abnormalities and abnormalities themselves were more severe than previously reported. This was attributed to an increased dose a...

journal_title：Cancer

authors： Jaffe N,Takaue Y,Anzai T,Robertson R

更新日期：1985-09-15 00:00:00

abstract：:Carcinoembryonic antigen (CEA) values in 529 patients treated in two consecutive adjuvant chemotherapy protocols were analyzed to determine if CEA values correlated with disease-free status or prognostic utility. CEA values were evaluated preoperatively, before chemotherapy, at the conclusion of chemotherapy, and duri...

journal_title：Cancer

authors： Theriault RL,Hortobagyi GN,Fritsche HA,Frye D,Martinez R,Buzdar AU

更新日期：1989-03-01 00:00:00