Radiation tolerance of the spinal cord.

Abstract:

:A series of nine cases of radiation myelopathy seen at the University of California, San Francisco (UCSF) is reviewed, and their treatment data converted into nominal single doses (NSD) and equivalent single doses (ED). The 1% incidence level of myelopathy in the thoracic cord is 1015 rets (ED), and the 50% incidence level is 1476rets (ED). Caution should be used when utilizing a rapid fractionation schedule; it appears that 2000 rads in 5 fractions and 3000 rads in 10 fractions is a safe regimen for the thoracic spinal cord.

journal_name

Cancer

journal_title

Cancer

authors

Wara WM,Phillips TL,Sheline GE,Schwade JG

doi

10.1002/1097-0142(197506)35:6<1558::aid-cncr282035

subject

Has Abstract

pub_date

1975-06-01 00:00:00

pages

1558-62

issue

6

eissn

0008-543X

issn

1097-0142

journal_volume

35

pub_type

杂志文章

相关文献

CANCER文献大全
  • Laboratory aids to diagnosis--enzymes.

    abstract::A summary is presented of those organ specific enzyme assays traditionally used in evaluation of the patient with cancer. In addition, the use of certain serum enzymes such as gamma-glutamyl transpeptidase, phosphohexose isomerase or 5'-nucleotidase as aids in following the course of the disease, particularly in patie...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/1097-0142(197601)37:1+<542::aid-cncr282037

    authors: Schwartz MK

    更新日期:1976-01-01 00:00:00

  • Oncoproteins and tumor progression in papillary thyroid carcinoma: presence of epidermal growth factor receptor, c-erbB-2 protein, estrogen receptor related protein, p21-ras protein, and proliferation indicators in relation to tumor recurrences and patien

    abstract:BACKGROUND:The prognostic relevance of activated oncogenes and oncoproteins has not been well studied in papillary thyroid cancer, which is slow-growing, with only regional spread in most cases. Therefore, the influence of some protein markers and tumor cell proliferation on disease progress in a series of patients wit...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19951101)76:9<1643::aid-cncr2820

    authors: Akslen LA,Varhaug JE

    更新日期:1995-11-01 00:00:00

  • Lymphocyte predominance Hodgkin's disease. A clinicopathologic reassessment.

    abstract::A clinicopathologic analysis of 35 cases of lymphocyte predominance Hodgkin's disease (LPHD) was performed, and the relationship between various histologic features and stage at presentation was examined. The series comprised 31 male and 4 female patients with a median age of 32 years. Twenty patients had Ann Arbor St...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19870101)59:1<99::aid-cncr282059

    authors: Trudel MA,Krikorian JG,Neiman RS

    更新日期:1987-01-01 00:00:00

  • Using data to effectively manage a national screening program.

    abstract::The National Breast and Cervical Cancer Early Detection Program (NBCCEDP) of the Centers for Disease Control and Prevention (CDC) is implemented through cooperative agreements with state health departments, US territories, and tribal health organizations (grantees). Grantees typically contract with clinicians and othe...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.28821

    authors: Yancy B,Royalty JE,Marroulis S,Mattingly C,Benard VB,DeGroff A

    更新日期:2014-08-15 00:00:00

  • Racial/ethnic differences in survival rates in a population-based series of men with breast carcinoma.

    abstract:BACKGROUND:A rare occurrence, about 1500 men in the United States develop breast carcinoma each year. Little is known about survival patterns at the population level, particularly about racial/ethnic variation. METHODS:Using data from the Surveillance, Epidemiology, and End Results Program, we examined survival rates ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.10521

    authors: O'Malley CD,Prehn AW,Shema SJ,Glaser SL

    更新日期:2002-06-01 00:00:00

  • Cure rate estimation and long-term prognosis of uterine cervix carcinoma.

    abstract::This paper reports the prognosis results of a retrospective study of over 2000 cases of uterine cervix carcinoma totally treated at Institut Gustave-Roussy from 1950 to 1963. From the study of their long-term survival, an overall cure rate was estimated at 49% seven years after the start of primary treatment. A study ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19810101)47:1<203::aid-cncr28204

    authors: Pejovic MH,Wolff JP,Kramar A,Goldfarb E

    更新日期:1981-01-01 00:00:00

  • Disparities in access to care at high-volume institutions for uro-oncologic procedures.

    abstract:BACKGROUND:Socioeconomic status represents an established barrier to health care access. Age, sex, and race may also play a role. The authors examined whether these affect the access to high-volume hospitals for uro-oncologic procedures in the United States. METHODS:Within the Nationwide Inpatient Sample (NIS), the au...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.27440

    authors: Trinh QD,Sun M,Sammon J,Bianchi M,Sukumar S,Ghani KR,Jeong W,Dabaja A,Shariat SF,Perrotte P,Agarwal PK,Rogers CG,Peabody JO,Menon M,Karakiewicz PI

    更新日期:2012-09-15 00:00:00

  • Patterns of the first lymph node metastases in patients with cutaneous malignant melanoma of axial localization.

    abstract::At the Finsen Institute, Copenhagen, from 1971 to 1981, 134 patients were treated for lymph node metastases from primary cutaneous malignant melanoma of axial localization (e.g., in the head and neck and trunk), where metastases to regional lymph node groups were the first sign of dissemination. Due to the lack of suf...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19881101)62:9<2073::aid-cncr2820

    authors: Lock-Andersen J,Partoft S,Jensen MG

    更新日期:1988-11-01 00:00:00

  • Ifosfamide with mesna uroprotection and etoposide in recurrent, refractory acute leukemia in childhood. A Pediatric Oncology Group Study.

    abstract:BACKGROUND:Ifosfamide has previously been shown to be active as a single agent and in combination with doxorubicin, etoposide, and teniposide in pediatric solid tumors and adult acute leukemia. The authors performed a dose-escalation trial of ifosfamide with a fixed dosage of etoposide, with mesna uroprotection, in chi...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1002/1097-0142(19930901)72:5<1790::aid-cncr2820

    authors: Bernstein ML,Whitehead VM,Devine S,Grier H,Kung F,Krischer J,Dreyer Z,Bell B,Land V,Buchanan GR

    更新日期:1993-09-01 00:00:00

  • Mucin 1 antigens in the serum and bronchial lavage fluid of patients with lung cancer.

    abstract:BACKGROUND:Lung cancer (LC) is the most common fatal malignancy, but there are no useful tumor markers for diagnosis or monitoring. Mucin 1 has an established role as a marker in other malignancies, but has undergone limited assessment in LC. METHODS:Serum from 86 patients with LC and 24 with benign pulmonary disease ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19931115)72:10<2936::aid-cncr282

    authors: Willsher PC,Xing PX,Clarke CP,Ho DW,McKenzie IF

    更新日期:1993-11-15 00:00:00

  • Stage I small cell carcinoma of the vulva treated with vulvectomy, lymphadenectomy, and adjuvant chemotherapy.

    abstract::Neuroendocrine small cell carcinoma is a lethal, but rare, tumor that arises most frequently in the lung. Small cell cancer also rarely may occur in the female genital tract, usually in the cervix. This article concerns the fourth reported case of neuroendocrine small cell carcinoma of the vulva. Previously, small cel...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/1097-0142(19910501)67:9<2415::aid-cncr2820

    authors: Cliby W,Soisson AP,Berchuck A,Clarke-Pearson DL

    更新日期:1991-05-01 00:00:00

  • External radiotherapy in thyroid cancers.

    abstract::Surgery is the most effective treatment for thyroid cancer; however, in some subsets of patients, the role of radiotherapy (RT) is important. The main indication for external-beam RT is incomplete surgery. When neoplastic tissue is left behind at operation, RT must be considered, but only if an experienced surgeon fee...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19850501)55:9+<2062::aid-cncr282

    authors: Tubiana M,Haddad E,Schlumberger M,Hill C,Rougier P,Sarrazin D

    更新日期:1985-05-01 00:00:00

  • Phase II study of patients with metastatic nonsmall cell carcinoma of the lung treated with paclitaxel by 3-hour infusion.

    abstract:BACKGROUND:Single-agent chemotherapy produces partial responses in the range of 7-27% in patients with Stage IV nonsmall cell lung carcinoma (NSCLC). Cisplatin-based combination regimens have achieved higher response rates but with significant toxicity. Two prior studies employing 24-hour infusions of paclitaxel showed...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:

    authors: Tester WJ,Jin PY,Reardon DH,Cohn JB,Cohen MH

    更新日期:1997-02-15 00:00:00

  • Relationship between 5-fluorouracil (5-FU) dose intensity and therapeutic response in patients with advanced colorectal cancer receiving infusional therapy containing 5-FU.

    abstract:BACKGROUND:A phase II prospective trial was carried out to study the concept of 5-fluorouracil (5-FU) dose-intensity in patients with advanced colorectal cancer. Forty patients were treated with 5-FU plus leucovorin (LV), with individually increasing doses of 5-FU. A 5-FU pharmacokinetic follow up was performed and a r...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/(SICI)1097-0142(19960201)77:3<441::AID-CNC

    authors: Gamelin EC,Danquechin-Dorval EM,Dumesnil YF,Maillart PJ,Goudier MJ,Burtin PC,Delva RG,Lortholary AH,Gesta PH,Larra FG

    更新日期:1996-02-01 00:00:00

  • Mucinous tumors of the ovary. Ultrastructural studies of mucinous cystadenomas with histogenetic considerations.

    abstract::On the basis of light microscopic and scanning and transmission ultrastructural observations, we have classified benign mucinous ovarian neoplasms into two types: a pure endocervical type and a mixed intestinal endocervical type. We have also reviewed the literature pertinent to the histogenetic origin of the ovarian ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197511)36:5<1709::aid-cncr282036

    authors: Fenoglio CM,Ferenczy A,Richart RM

    更新日期:1975-11-01 00:00:00

  • Primary cardiac tumors: forty years' experience with 71 patients.

    abstract:BACKGROUND:Primary cardiac tumors are infrequent, and few cardiac surgeons have extensive experience in treating them. The majority of the tumors are benign. As noninvasive diagnostic imaging of cardiac masses continues to improve, the number of these tumors that are seen by clinicians will increase. More of the malign...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0142(19970501)79:9<1809::aid-cn

    authors: Perchinsky MJ,Lichtenstein SV,Tyers GF

    更新日期:1997-05-01 00:00:00

  • New presentation of alpha heavy chain disease: North American polypoid gastrointestinal lymphoma. Clinical and cellular studies.

    abstract::Alpha Heavy Chain Disease has generally been described in the Mediterranean area in young people with a diffuse gastrointestinal lymphoma and malabsorption. We describe a patient from the United States with polypoid lymphoma of the gastrointestinal tract and a prolonged clinical course, who had the characteristic alph...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197803)41:3<1161::aid-cncr282041

    authors: Cohen HJ,Gonzalvo A,Krook J,Thompson TT,Kremer WB

    更新日期:1978-03-01 00:00:00

  • Soft tissue sarcoma brain metastases. Prevalence in a cohort of 3829 patients.

    abstract:BACKGROUND:Brain metastases from soft tissue sarcoma (STS) are uncommon. To the authors' knowledge limited information is available regarding the influence of the initial STS site, the significance of parenchymal versus leptomeningeal metastases, and the role of surgical resection. METHODS:STS patients evaluated betwe...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.10554

    authors: Espat NJ,Bilsky M,Lewis JJ,Leung D,Brennan MF

    更新日期:2002-05-15 00:00:00

  • Improving prognosis of glioblastoma in the 21st century: who has benefited most?

    abstract:BACKGROUND:Glioblastoma multiforme (GBM) is the most frequent primary brain tumor in adults. Temozolomide was rapidly incorporated into first-line treatment following the publication of the pivotal European Organization for Research and Treatment of Cancer-National Cancer Institute of Canada phase 3 trial in 2005. Howe...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.26685

    authors: Lawrence YR,Mishra MV,Werner-Wasik M,Andrews DW,Showalter TN,Glass J,Shen X,Symon Z,Dicker AP

    更新日期:2012-09-01 00:00:00

  • Biology of the human malignant lymphomas. IV. Functional characterization of ten diffuse histiocytic lymphoma cell lines.

    abstract::Ten consecutive diffuse histiocytic lymphoma (DHL) cell lines established in our laboratory were studied for the presence of Epstein-Barr virus (EBV) genomes, lysozyme, nonspecific esterase and other cytochemical reactions, phagocytic activity, cytoplasmic immunoglobulin light and heavy chains, and surface receptors t...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/1097-0142(197811)42:5<2379::aid-cncr282042

    authors: Epstein AL,Levy R,Kim H,Henle W,Henle G,Kaplan HS

    更新日期:1978-11-01 00:00:00

  • A multivariate analysis of the survival of patients with aggressive lymphoma: variations in the predictive value of prognostic factors during the course of the disease. Groupe d'Etudes des Lymphomes de l'Adulte.

    abstract:BACKGROUND:Aggressive non-Hodgkin's lymphoma is now often curable with chemotherapy. The International Prognostic Index (IPI) was recently developed to predict patient survival on the basis of pretreatment clinical features. However, classical multivariate regression models such as the IPI fail to detect time-dependent...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:

    authors: Mounier N,Morel P,Haioun C,Coiffier B,Tilly H,Chatelain C,Lederlin P,Thyss A,Herbrecht R,Gisselbrecht C,Lepage E

    更新日期:1998-05-15 00:00:00

  • Smoking status and survival in the national comprehensive cancer network non-small cell lung cancer cohort.

    abstract:BACKGROUND:The objectives of this study were to evaluate survival among current smokers, former smokers, and never smokers who are diagnosed with non-small cell lung cancer (NSCLC). METHODS:The study included patients who participated in the National Comprehensive Cancer Network's NSCLC Database Project. Current, form...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.27824

    authors: Ferketich AK,Niland JC,Mamet R,Zornosa C,D'Amico TA,Ettinger DS,Kalemkerian GP,Pisters KM,Reid ME,Otterson GA

    更新日期:2013-02-15 00:00:00

  • Pediatric melanoma in melanoma-prone families.

    abstract:BACKGROUND:In the United States, only approximately 0.4% of all melanomas are diagnosed in patients aged <20 years. To the authors' knowledge, melanoma in pediatric members of melanoma-prone families has not been fully investigated to date. The objective of the current study was to evaluate pediatric patients with mela...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.31641

    authors: Goldstein AM,Stidd KC,Yang XR,Fraser MC,Tucker MA

    更新日期:2018-09-15 00:00:00

  • Correlation of cell-cycle kinetics, hormone receptors, histopathology, and nodal status in human breast cancer.

    abstract::DNA ploidy and percent of (%S-phase) S-phase cells were determined from the DNA content distribution of 21 benign and 76 malignant (69 primary, 7 metastatic) breast tumors using flow cytometry. All of the benign tumors were diploid, whereas 89% of the malignant tumors had measurable aneuploidy. Multiple stem-lines wer...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19841015)54:8<1586::aid-cncr2820

    authors: Moran RE,Black MM,Alpert L,Straus MJ

    更新日期:1984-10-15 00:00:00

  • Prognostic factors for clinically localized prostate carcinoma: analysis of 938 patients irradiated in the prostate specific antigen era.

    abstract:BACKGROUND:Pretreatment serum prostate specific antigen (PSA) level is a powerful prognostic factor for clinically localized prostate carcinoma. The traditional prognostic factors, T classification and Gleason score, appear to have been relegated to a minor position. This study was conducted to evaluate the relative pr...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:

    authors: Zagars GK,Pollack A,von Eschenbach AC

    更新日期:1997-04-01 00:00:00

  • Cardiovascular disease in survivors of hematopoietic cell transplantation.

    abstract::Hematopoietic cell transplantation (HCT) is increasingly offered as a curative option for many patients with hematologic malignancies. Improvements in HCT strategies and supportive care have resulted in a growing number of long-term survivors. However, these survivors are at an increased risk of developing long-term d...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/cncr.28444

    authors: Armenian SH,Chow EJ

    更新日期:2014-02-15 00:00:00

  • Chemoprevention of bladder cancer.

    abstract::There is a growing body of basic science and epidemiologic evidence to support a research thrust to determine whether several natural or synthetic agents, given alone or together, can lower cancer incidence. Candidate agents include analogs of vitamin A and the vitamin A precursor, beta-carotene, vitamins C and E, and...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/1097-0142(19870801)60:3+<650::aid-cncr2820

    authors: Malone WF,Kelloff GJ,Pierson H,Greenwald P

    更新日期:1987-08-01 00:00:00

  • Acupressure bands do not improve chemotherapy-induced nausea control in pediatric patients receiving highly emetogenic chemotherapy: A single-blinded, randomized controlled trial.

    abstract:BACKGROUND:Chemotherapy-induced nausea and vomiting remain common, distressing side effects of chemotherapy. It has been reported that acupressure prevents chemotherapy-induced nausea in adults, but it has not been well studied in children. METHODS:In this multicenter, prospective, randomized, single-blind, sham-contr...

    journal_title:Cancer

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1002/cncr.31198

    authors: Dupuis LL,Kelly KM,Krischer JP,Langevin AM,Tamura RN,Xu P,Chen L,Kolb EA,Ullrich NJ,Sahler OJZ,Hendershot E,Stratton A,Sung L,McLean TW

    更新日期:2018-03-15 00:00:00

  • Expression and prognostic role of tumor suppressor gene PTEN/MMAC1/TEP1 in hepatocellular carcinoma.

    abstract:BACKGROUND:Inactivation of the tumor suppressor gene PTEN/MMAC1/TEP1, located on chromosome 10q23, is a common event in advanced stages of diverse human malignancies. However, the prognostic role of PTEN expression in patients with hepatocellular carcinoma (HCC) has not been characterized. METHODS:One hundred five res...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.11266

    authors: Hu TH,Huang CC,Lin PR,Chang HW,Ger LP,Lin YW,Changchien CS,Lee CM,Tai MH

    更新日期:2003-04-15 00:00:00

  • Activity of temozolomide and bevacizumab in the treatment of locally advanced, recurrent, and metastatic hemangiopericytoma and malignant solitary fibrous tumor.

    abstract:BACKGROUND:Hemangiopericytomas and malignant solitary fibrous tumors (HPC/SFT) are rare, closely related sarcomas with unpredictable behavior that respond infrequently to chemotherapy. An optimal systemic treatment strategy for advanced HPC/SFT has not yet been identified. METHODS:We retrospectively analyzed the recor...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.26098

    authors: Park MS,Patel SR,Ludwig JA,Trent JC,Conrad CA,Lazar AJ,Wang WL,Boonsirikamchai P,Choi H,Wang X,Benjamin RS,Araujo DM

    更新日期:2011-11-01 00:00:00