Activity of temozolomide and bevacizumab in the treatment of locally advanced, recurrent, and metastatic hemangiopericytoma and malignant solitary fibrous tumor.

abstract：:Epidemiology and prognosis were analyzed in a consecutive, population-based series of 137 patients with malignant fibrous histiocytoma of soft tissue in the extremities and trunk wall, with a complete follow-up of minimum 3 years. All but one patient were treated by surgery in 28 cases combined with adjuvant radiother...

journal_title：Cancer

authors： Rööser B,Willén H,Gustafson P,Alvegård TA,Rydholm A

更新日期：1991-01-15 00:00:00

abstract：BACKGROUND:The current study sought to delineate prospectively the rates and clinical course of emotional distress, cognitive impairment, and quality of life (QOL) in chemotherapy-naive patients with cancer and to consider the determinants of global QOL. METHODS:Patients who consented to participate were administered ...

journal_title：Cancer

authors： Iconomou G,Mega V,Koutras A,Iconomou AV,Kalofonos HP

更新日期：2004-07-15 00:00:00

abstract：BACKGROUND:Previous studies have shown that low levels of p27(Kip1), an inhibitor of G1 cyclin-dependent kinases, are associated with high aggressiveness and poor prognosis in a variety of cancers. Decreased levels of p27 are caused, at least in part, by acceleration of the rate of its ubiquitin-mediated degradation. I...

journal_title：Cancer

authors： Hershko D,Bornstein G,Ben-Izhak O,Carrano A,Pagano M,Krausz MM,Hershko A

更新日期：2001-05-01 00:00:00

abstract：:A 20-year-old man with previously treated lymphoblastic lymphoma, a known T-cell disorder, developed progressive disease despite intensive combination chemotherapy with doxorubicin, vincristine, and prednisone. He was subsequently treated with a 21-day course of intravenous antithymocyte globulin at a dose of approxim...

journal_title：Cancer

authors： Wong KK Jr,Sweet DL,Variakojis D

更新日期：1982-07-01 00:00:00

abstract：:In a study conducted by the Eastern Cooperative Oncology Group, 51 evaluable women with advanced ovarian carcinoma were randomized to either abdominal radiation therapy alone, chlorambucil alone, or to a combination of radiation therapy and chlorambucil by members of the Eastern Cooperative Oncology Group. Provision w...

journal_title：Cancer

authors： Miller SP,Brenner S,Horton J,Stolbach L,Shnider BI,Pocock S

更新日期：1975-11-01 00:00:00

abstract：BACKGROUND:Cetuximab in combination with docetaxel was examined in chemotherapy-refractory/resistant patients with advanced nonsmall-cell lung cancer (NSCLC) to determine response rate, survival, safety, and pharmacokinetics (PK). METHODS:Patients had evidence of epidermal growth factor receptor (EGFR) expression (> o...

journal_title：Cancer

authors： Kim ES,Mauer AM,William WN Jr,Tran HT,Liu D,Lee JJ,Windt P,Hong WK,Vokes EE,Herbst RS

更新日期：2009-04-15 00:00:00

abstract：:The monitoring utility of serial patterns of a single marker (carcinoembryonic antigen) level and multiple marker (three carbohydrates-fucose, mannose and galactose) levels in patients with small cell carcinoma of the lung was investigated using a quantitative approach. A serial multiple regression (SMR) model was for...

journal_title：Cancer

authors： Woo KB,Waalkes P,Abeloff MD,Ettinger DS,McNitt KL,Gehrke CW

更新日期：1981-10-01 00:00:00

abstract：BACKGROUND:Carboplatin-based regimens have demonstrated activity in pediatric patients with low-grade glioma (LGG). However, carboplatin hypersensitivity reaction (Cb HSR) represents a common and limiting factor for the continuation of therapy. METHODS:The objectives of this study were to describe the prevalence, char...

journal_title：Cancer

authors： Lafay-Cousin L,Sung L,Carret AS,Hukin J,Wilson B,Johnston DL,Zelcer S,Silva M,Odame I,Mpofu C,Strother D,Bouffet E

更新日期：2008-02-15 00:00:00

abstract：BACKGROUND:Tyrosine kinase inhibitors (TKIs) of the epidermal growth factor receptor (EGFR) have activity in solid tumors. The authors evaluated an oral EGFR TKI, erlotinib, in patients with previously treated esophageal cancer. METHODS:Thirty patients with measurable, metastatic cancer of the esophageal and gastroeso...

journal_title：Cancer

authors： Ilson DH,Kelsen D,Shah M,Schwartz G,Levine DA,Boyd J,Capanu M,Miron B,Klimstra D

更新日期：2011-04-01 00:00:00

abstract：:The incidence of breast cancer rose about 1% per year between 1940 and 1980 according to data in the Connecticut Tumor Registry. A sharp increase of 32% was reported between 1980 and 1987 in the Surveillance, Epidemiology and End Results Program of the National Cancer Institute. Data from this program shows that the i...

journal_title：Cancer

authors： Garfinkel L,Boring CC,Heath CW Jr

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND:In spite of many reports, it remains unclear whether the presence of tumor cells in circulating blood flow predicts a poor prognosis. METHODS:Competitive seminested reverse transcriptase-polymerase chain reaction (RT-PCR), a technique for the quantitative detection of tumor cells, was applied to detect the ...

journal_title：Cancer

authors： Sadahiro S,Suzuki T,Tokunaga N,Yurimoto S,Yasuda S,Tajima T,Makuuchi H,Murayama C,Matsuda K

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:Although it induces a relevant reduction in the risk of both visceral metastases and locoregional recurrences, the combination of chemotherapy and surgery only marginally improves the survival of patients with Stage IIIA(N2) (International Union Against Cancer staging and classification system) nonsmall-cell...

journal_title：Cancer

authors： Andre F,Grunenwald D,Pujol JL,Girard P,Dujon A,Brouchet L,Brichon PY,Westeel V,Le Chevalier T

更新日期：2001-06-15 00:00:00

abstract：:Two published cases of medulloepithelioma, a rare malignant pediatric brain tumor composed of a mixture of primitive neuroepithelium and its differentiated neuronal and glial descendants, were examined by immunohistochemical staining for the presence of growth factors. From a panel of antibodies, those identifying bas...

journal_title：Cancer

authors： Shiurba RA,Buffinger NS,Spencer EM,Urich H

更新日期：1991-08-15 00:00:00

abstract：:To assess the efficacy and safety of Adriamycin (Adria Laboratories, Columbus, OH) in inoperable hepatocellular carcinoma (HCC), 60 patients were randomized to receive Adriamycin 60 to 75 mg/m2 at 3-week intervals and 46 patients to receive no antitumor therapy. The median survival rate of the Adriamycin group was 10....

journal_title：Cancer

authors： Lai CL,Wu PC,Chan GC,Lok AS,Lin HJ

更新日期：1988-08-01 00:00:00

abstract：:Two patients developed extremely bizarre (pseudomalignant) granulation-tissue reactions in the larynx and facial sinuses, following radiation therapy for carcinoma. Containing pleomorphic spindle cells and numerous (sometimes atypical) mitotic figures, both tumefactive lesions simulated high grade malignancies. While ...

journal_title：Cancer

authors： Weidner N,Askin FB,Berthrong M,Hopkins MB,Kute TE,McGuirt FW

更新日期：1987-04-15 00:00:00

abstract：BACKGROUND:Estrogen receptor-alpha (ERalpha) is variably expressed in hepatocellular carcinoma (HCC) and is believed to be correlated with prognosis and survival. Recently, another estrogen receptor (ERbeta) has been identified, but its relevance in liver diseases is unknown. METHODS:The expression of ERbeta in the li...

journal_title：Cancer

authors： Iavarone M,Lampertico P,Seletti C,Francesca Donato M,Ronchi G,del Ninno E,Colombo M

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Achieving a pathologic complete response (pCR) with neoadjuvant chemotherapy (NAC) in patients with muscle-invasive bladder cancer (MIBC) has been associated with improved overall survival (OS). This study was aimed at evaluating the impact of pathologic downstaging (pDS; ie, a pT stage at least 1 stage lowe...

journal_title：Cancer

authors： Martini A,Jia R,Ferket BS,Waingankar N,Plimack ER,Crabb SJ,Harshman LC,Yu EY,Powles T,Rosenberg JE,Pal SK,Vaishampayan UN,Necchi A,Wiklund NP,Mehrazin R,Mazumdar M,Sfakianos JP,Galsky MD

更新日期：2019-09-15 00:00:00

abstract：BACKGROUND:The authors undertook a prospective evaluation of the clinical value of 2-fluoro [18-]-2-deoxyglucose positron emission tomography (FDG-PET) in the detection and staging of malignant lymphoma compared with computed tomography (CT) and bone marrow biopsy (BMB). METHODS:Fifty-two consecutive patients with unt...

journal_title：Cancer

authors： Buchmann I,Reinhardt M,Elsner K,Bunjes D,Altehoefer C,Finke J,Moser E,Glatting G,Kotzerke J,Guhlmann CA,Schirrmeister H,Reske SN

更新日期：2001-03-01 00:00:00

abstract：:Mesenchymal chondrosarcoma of bone and soft tissues treated at the Istituto Ortopedico Rizzoli are reviewed. The skeletal locations were prominent in five cases. Only two cases were in the soft tissues. Radiographic picture in the bone shows an aggressive osteolysis, with soft tissues invasion. Histologic picture is t...

journal_title：Cancer

authors： Bertoni F,Picci P,Bacchini P,Capanna R,Innao V,Bacci G,Campanacci M

更新日期：1983-08-01 00:00:00

abstract：:The correlation between clinicopathologic findings and point mutation in codon 12 of c-Ki-ras gene was examined in primary lung adenocarcinomas using polymerase chain reaction and oligonucleotide hybridization techniques. The mutation was detected in ten of 67 cases (15%). Microscopically, mutation-positive cases reve...

journal_title：Cancer

authors： Kobayashi T,Tsuda H,Noguchi M,Hirohashi S,Shimosato Y,Goya T,Hayata Y

更新日期：1990-07-15 00:00:00

abstract：:Forty-four patients with advanced carcinoma of the head and neck were treated with cyclophosphamide, 400 mg/m2 plus BCNU, 100 mg/m2 day 1 followed by adriamycin 40 mg/m2 day 2, with therapy repeated every 4 weeks. Of 31 evaluable patients, there were 1 complete response, and 10 partial responses (35%). Four of 8 patie...

journal_title：Cancer

authors： Presant CA,Ratkin G,Klahr C,Brown C

更新日期：1979-11-01 00:00:00

abstract：:This article documents the study of 383 cases of lung cancer in uranium miners and presents for the first time the relationship of radioactive radon gas and cigarette smoking. There is evidence that alpha radiation from radon gas at exposure levels above 465 working level months (WLM) is a strong contributor to the de...

journal_title：Cancer

authors： Saccomanno G,Huth GC,Auerbach O,Kuschner M

更新日期：1988-10-01 00:00:00

abstract：:Elective irradiation of sites of potential occult tumor spread is often part of a patient's radiation therapy program. The required radiation dose (D) depends on the probability that occult disease exists (P(occ)), the number of sites at risk (A), the number of tumor clonogens present (Ni), their radiation sensitivity...

journal_title：Cancer

authors： Marks LB

更新日期：1990-12-15 00:00:00

abstract：:The present study was carried out to investigate a distinctive type of carcinoma of the uterine cervix categorized under the designation as circumscribed carcinoma with lymphocytic infiltration. Grossly this carcinoma is characterized by defined circumscription with a superficial ulceration. A microscropic feature cha...

journal_title：Cancer

authors： Hasumi K,Sugano H,Sakamoto G,Masubuchi K,Kubo H

更新日期：1977-06-01 00:00:00

abstract：BACKGROUND:Squamous cell carcinoma of the esophagus is endemic in parts of South Africa. Previous case-control studies have shown many associations but no clear etiologic pathway has been established. METHODS:A case-control study of dietary and social factors was performed for 130 patient/control pairs matched for age...

journal_title：Cancer

authors： Sammon AM

更新日期：1998-08-01 00:00:00

abstract：:Quality indicators applicable to cancer end-of-life care exist, but have not been widely implemented. To advance this field, the authors worked with the Agency for Health Care Research and Quality and the National Cancer Institute to organize a national symposium to discuss key issues and future goals, based on a conc...

journal_title：Cancer

authors： Seow H,Snyder CF,Shugarman LR,Mularski RA,Kutner JS,Lorenz KA,Wu AW,Dy SM

更新日期：2009-09-01 00:00:00

abstract：:On the basis of light microscopic and scanning and transmission ultrastructural observations, we have classified benign mucinous ovarian neoplasms into two types: a pure endocervical type and a mixed intestinal endocervical type. We have also reviewed the literature pertinent to the histogenetic origin of the ovarian ...

journal_title：Cancer

authors： Fenoglio CM,Ferenczy A,Richart RM

更新日期：1975-11-01 00:00:00

abstract：BACKGROUND:Ligand activation of peroxisome proliferator-activated receptor gamma (PPARgamma) results in the inhibition of proliferation of various cancer cells. The aim of this study is to investigate the mechanisms of cell growth inhibition of hepatocellular carcinoma (HCC) cell lines by the PPARgamma ligand, troglita...

journal_title：Cancer

authors： Yoshizawa K,Cioca DP,Kawa S,Tanaka E,Kiyosawa K

更新日期：2002-11-15 00:00:00

abstract：BACKGROUND:Despite the characteristic histopathologic appearance of alveolar soft-part sarcoma (ASPS), its histogenesis remains unclear, and cytogenetic analysis of ASPS is limited to eight cases so far because of the extreme rarity of this disease. METHODS:The authors document a cytogenetic study of a primary case of...

journal_title：Cancer

authors： Joyama S,Ueda T,Shimizu K,Kudawara I,Mano M,Funai H,Takemura K,Yoshikawa H

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:Several histologic classifications of thymomas have been proposed, and attempts have been made to correlate the different histologic subtypes to clinical behavior and prognosis. Recently, Marino and Müller-Hermelink and Kirchner et al. proposed a new morphologic classification of thymomas based on the resemb...

journal_title：Cancer

authors： Quintanilla-Martinez L,Wilkins EW Jr,Choi N,Efird J,Hug E,Harris NL

更新日期：1994-07-15 00:00:00