Developing quality indicators for cancer end-of-life care: proceedings from a national symposium.

Abstract:

:Quality indicators applicable to cancer end-of-life care exist, but have not been widely implemented. To advance this field, the authors worked with the Agency for Health Care Research and Quality and the National Cancer Institute to organize a national symposium to discuss key issues and future goals, based on a conceptual framework. Discussions focused on 8 key domains in end-of-life cancer care: pain; dyspnea; communication, care planning, and decision making; psychosocial care; communication about chemotherapy; depression; continuity, coordination, and care transitions; and spirituality and closure. Key themes included the need for clarity on definitions and key aspects of care within domains, the need to start implementing indicators in more developed domains, and the importance of high-quality symptom assessment and documentation of key processes. Key areas for future work include development of more outcome indicators, methods to better incorporate indicators and patient-reported outcomes into clinical processes of care, and coordination across domains and settings. Measuring the quality of end-of-life cancer care is essential to understanding how best to improve patient outcomes and care.

journal_name

Cancer

journal_title

Cancer

authors

Seow H,Snyder CF,Shugarman LR,Mularski RA,Kutner JS,Lorenz KA,Wu AW,Dy SM

doi

10.1002/cncr.24439

subject

Has Abstract

pub_date

2009-09-01 00:00:00

pages

3820-9

issue

17

eissn

0008-543X

issn

1097-0142

journal_volume

115

pub_type

相关文献

CANCER文献大全
  • Papanicolaou smear sensitivity for the detection of adenocarcinoma of the cervix: a study of 49 cases.

    abstract:BACKGROUND:Papanicolaou smear sensitivity for cervical adenocarcinoma (CVCA) is not well established. Also uncertain are the relative contributions to falsely negative diagnoses of sampling, screening, and interpretive errors. METHODS:Papanicolaou smears were identified from all patients at our institutions with biops...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:

    authors: Krane JF,Granter SR,Trask CE,Hogan CL,Lee KR

    更新日期:2001-02-25 00:00:00

  • Distribution and reproducibility of aryl hydrocarbon hydroxylase inducibility in a prospective population study of middle-aged male smokers and nonsmokers.

    abstract::Aryl hydrocarbon hydroxylase (AHH) inducibility was determined in a lymphoblast test system in 2,000 consecutive middle-aged male smokers, 304 ex-smokers, and 218 never-smokers in the same birth-year cohorts. Intraindividual, intraobserver, and interobserver, as well as temporal, reproducibility was checked in a speci...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19851015)56:8<1988::aid-cncr2820

    authors: Trell L,Korsgaard R,Janzon L,Trell E

    更新日期:1985-10-15 00:00:00

  • Pretreatment and routine echocardiogram monitoring during chemotherapy for anthracycline-induced cardiotoxicity rarely identifies significant cardiac dysfunction or alters treatment decisions: a 5-year review at a single pediatric oncology center.

    abstract:BACKGROUND:The widespread use of anthracycline chemotherapy has contributed to improved outcomes in children with cancer. The most feared complication of the anthracyclines is cardiotoxicity. Routine echocardiographic monitoring typically is used before, during, and after treatment to minimize cardiotoxicity. The ideal...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.26481

    authors: Watts RG,George M,Johnson WH Jr

    更新日期:2012-04-01 00:00:00

  • Comparative genomic hybridization analysis of genetic aberrations associated with development and progression of biliary tract carcinomas.

    abstract:BACKGROUND:Little is known about genetic aberrations associated with development and progression of biliary tract carcinomas. METHODS:To study chromosomal aberrations associated with development and progression of biliary tract carcinomas, the authors used comparative genomic hybridization to examine 50 such carcinoma...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(20010201)91:3<570::aid-cncr1036>

    authors: Shiraishi K,Okita K,Harada T,Kusano N,Furui T,Kondoh S,Oga A,Kawauchi S,Fukumoto Y,Sasaki K

    更新日期:2001-02-01 00:00:00

  • Obesity at diagnosis is associated with inferior outcomes in hormone receptor-positive operable breast cancer.

    abstract:BACKGROUND:Obesity has been associated with inferior outcomes in operable breast cancer, but the relation between body mass index (BMI) and outcomes by breast cancer subtype has not been previously evaluated. METHODS:The authors evaluated the relation between BMI and outcomes in 3 adjuvant trials coordinated by the Ea...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.27527

    authors: Sparano JA,Wang M,Zhao F,Stearns V,Martino S,Ligibel JA,Perez EA,Saphner T,Wolff AC,Sledge GW Jr,Wood WC,Fetting J,Davidson NE

    更新日期:2012-12-01 00:00:00

  • Outcome of palliative urinary diversion in the treatment of advanced malignancies.

    abstract:BACKGROUND:It is unclear whether palliative endourologic or percutaneous urinary diversion in the treatment of advanced cancer provides significant improvement in quality or duration of life. The purpose of this study was to evaluate survival and performance status after endourologic palliative urinary diversion in pat...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0142(19990215)85:4<998::aid-cnc

    authors: Shekarriz B,Shekarriz H,Upadhyay J,Banerjee M,Becker H,Pontes JE,Wood DP Jr

    更新日期:1999-02-15 00:00:00

  • Infections in patients with aplastic anemia: experience at a tertiary care cancer center.

    abstract:BACKGROUND:Infection is a significant cause of death in patients with aplastic anemia (AA). However, few recent studies have examined infectious complications in patients with AA. METHODS:The authors retrospectively evaluated the type of infections, associated pathogens, and outcome of infectious episodes (IEs) in pat...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.11478

    authors: Torres HA,Bodey GP,Rolston KV,Kantarjian HM,Raad II,Kontoyiannis DP

    更新日期:2003-07-01 00:00:00

  • Coexistence of chronic myelogenous leukemia and chronic lymphocytic leukemia.

    abstract::A 55-year-old man is reported who initially developed chronic lymphocytic leukemia. Seven years later, after chemotherapy with chlorambucil, chronic myelogenous leukemia was diagnosed in addition to the chronic lymphocytic leukemia. Four previously reported cases with the same sequence of events are reviewed as well a...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(1984)54:4<697::aid-cncr282054041

    authors: Schreiber ZA,Axelrod MR,Abebe LS

    更新日期:1984-08-15 00:00:00

  • A multicenter study of patients with multisystem Langerhans cell histiocytosis who develop secondary hemophagocytic lymphohistiocytosis.

    abstract:BACKGROUND:Langerhans cell histiocytosis (LCH) is a rare myeloid neoplasm characterized by the presence of abnormal CD1a-positive (CD1a+ )/CD207+ histiocytes. Hemophagocytic lymphohistiocytosis (HLH) represents a spectrum of hyperinflammatory syndromes typified by the dysregulated activation of the innate and adaptive ...

    journal_title:Cancer

    pub_type: 杂志文章,多中心研究

    doi:10.1002/cncr.31893

    authors: Chellapandian D,Hines MR,Zhang R,Jeng M,van den Bos C,Santa-María López V,Lehmberg K,Sieni E,Wang Y,Nakano T,Williams JA,Fustino NJ,Astigarraga I,Dunkel IJ,Abla O,van Halteren AGS,Pei D,Cheng C,Weitzman S,Sung L,N

    更新日期:2019-03-15 00:00:00

  • Serum HER-2/neu and relative resistance to trastuzumab-based therapy in patients with metastatic breast cancer.

    abstract:BACKGROUND:Previous reports based on small patient numbers suggested that changes in serum HER-2/neu levels may predict response or lack of response to trastuzumab-based therapies in metastatic breast cancer (MBC). The objectives of this study were to pool data from 307 patients with MBC from 7 medical institutions to ...

    journal_title:Cancer

    pub_type: 杂志文章,多中心研究

    doi:10.1002/cncr.23689

    authors: Ali SM,Carney WP,Esteva FJ,Fornier M,Harris L,Köstler WJ,Lotz JP,Luftner D,Pichon MF,Lipton A,Serum HER-2\/neu Study Group.

    更新日期:2008-09-15 00:00:00

  • Young and uninsured: Insurance patterns of recently diagnosed adolescent and young adult cancer survivors in the AYA HOPE study.

    abstract:BACKGROUND:Young adults have historically been the least likely to have health insurance in the United States. Previous studies of survivors of childhood cancer found lower rates of insurance and less access to medical care compared with siblings; however, to the authors' knowledge, no studies to date have examined con...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.28685

    authors: Parsons HM,Schmidt S,Harlan LC,Kent EE,Lynch CF,Smith AW,Keegan TH,AYA HOPE Collaborative.

    更新日期:2014-08-01 00:00:00

  • Breast conservation therapy in the United States following the 1990 National Institutes of Health Consensus Development Conference on the treatment of patients with early stage invasive breast carcinoma.

    abstract:BACKGROUND:A National Institutes of Health (NIH) Consensus Development Conference on the treatment of patients with early stage invasive breast carcinoma, held in June 1990, recommended breast conservation therapy for the majority of women with Stage I or II breast carcinoma. The authors evaluated the national use of b...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:

    authors: Lazovich D,Solomon CC,Thomas DB,Moe RE,White E

    更新日期:1999-08-15 00:00:00

  • Risk of contralateral breast cancer. Associations with histologic, clinical, and therapeutic factors.

    abstract::A case-control study was conducted to assess the risk factors associated with the development of a contralateral primary breast cancer among women who had had a first primary breast cancer. Hospital records were reviewed for 292 women with an incident contralateral breast cancer, diagnosed in one of eight hospitals be...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19880715)62:2<412::aid-cncr28206

    authors: Horn PL,Thompson WD

    更新日期:1988-07-15 00:00:00

  • High-dose tamoxifen and sulindac as first-line treatment for desmoid tumors.

    abstract:BACKGROUND:Desmoid tumors are mesenchymal nonmetastasizing neoplasms. Although rare in the general population, they are a common extracolonic manifestation of familial adenomatous polyposis (FAP). Because of high tumor recurrence rates, surgery has been less than satisfactory in the treatment of desmoid tumors. In the ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.11937

    authors: Hansmann A,Adolph C,Vogel T,Unger A,Moeslein G

    更新日期:2004-02-01 00:00:00

  • Expression of Fas antigen (CD95) in peripheral blood lymphocytes and in liver-infiltrating, cytotoxic lymphocytes in patients with hepatocellular carcinoma.

    abstract:BACKGROUND:Fas-expressing cytotoxic T lymphocytes (CTLs) are important antitumor immune effector cells in patients with hepatocellular carcinoma (HCC). The role of transforming growth factor beta 1 (TGF-beta1) in modulating the expression of Fas by CTLs is not known in HCC. The objectives of this study were to characte...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(20011015)92:8<2136::aid-cncr1555

    authors: Yuen MF,Hughes RD,Heneghan MA,Langley PG,Norris S

    更新日期:2001-10-15 00:00:00

  • Clinical and cytogenetic characteristics of myelodysplastic syndromes developing myelofibrosis.

    abstract::Myelofibrosis occurs in various hematologic neoplasias, including myelodysplastic syndrome (MDS), with a relatively low incidence. To gain insight into the clinical and cytogenetic implications of MDS patients in whom myelofibrosis develops, statistical analysis was done on 82 primary MDS patients with successful cyto...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19910701)68:1<178::aid-cncr28206

    authors: Ohyashiki K,Sasao I,Ohyashiki JH,Murakami T,Iwabuchi A,Tauchi T,Saito M,Nakazawa S,Serizawa H,Ebihara Y

    更新日期:1991-07-01 00:00:00

  • Principles of early detection of cancer.

    abstract::Screening for the early detection of cancer offers the potential of increasing the number of patients whose cancer is diagnosed in a localized, curable stage. The operation of an efficient and effective early detection program requires that a number of conditions be fulfilled, some of which are difficult to attain. Fi...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19810301)47:5+<1142::aid-cncr282

    authors: Miller DG

    更新日期:1981-03-01 00:00:00

  • Applied cancer prevention in practice.

    abstract::In 1982, more than 125,000 cancer cases in the United States should be preventable. Every physician should advise all patients to eliminate all tobacco use, moderate alcohol use, avoid the use of drugs which are carcinogenic, minimize sun and x-ray exposure, maintain an ideal weight, and follow a "prudent" diet. Secon...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19830615)51:12+<2430::aid-cncr28

    authors: McKenna RJ

    更新日期:1983-06-15 00:00:00

  • DNA ploidy analysis of mucinous cystic tumors of the pancreas. Correlation of aneuploidy with malignancy and poor prognosis.

    abstract:BACKGROUND:Benign and malignant pancreatic mucinous tumors differ in proliferative activity, production of tumor markers, and expression of growth factors. DNA ploidy is a useful index of aggressiveness and poor survival in ductal adenocarcinoma, but has not been studied in pancreatic cystic tumors. METHODS:The DNA pl...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/(SICI)1097-0142(19960101)77:1<58::AID-CNCR

    authors: Southern JF,Warshaw AL,Lewandrowski KB

    更新日期:1996-01-01 00:00:00

  • Methotrexate: an active drug in bladder cancer.

    abstract::Forty-nine patients with transitional urothelial tract tumors received methotrexate: 0.5-1.0 mg/kg I.V. Q W (40 patients) or 250 mg/M2 in a 2-hour infusion with citrovorum factor rescue 24 hours later (nine patients). Eleven (26%, 95% confidence limits 13-39%) of 42 patients with bidimensionally measurable metastases ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19810315)47:6<1246::aid-cncr2820

    authors: Natale RB,Yagoda A,Watson RC,Whitmore WF,Blumenreich M,Braun DW Jr

    更新日期:1981-03-15 00:00:00

  • Hepatic veno-occlusive disease due to DTIC.

    abstract::A case of fulminant hepatic failure leading to death in a patient receiving DTIC for metastatic melanoma is presented. Autopsy revealed widespread centrilobular necrosis secondary to a veno-occlusive process. There was no evidence of a similar process in other organs, and common causes of similar pathology were ruled ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19800515)45:10<2670::aid-cncr282

    authors: Asbury RF,Rosenthal SN,Descalzi ME,Ratcliffe RL,Arseneau JC

    更新日期:1980-05-15 00:00:00

  • Adriamycin, BCNU plus cyclophosphamide (ABC) in advanced carcinoma of the head and neck.

    abstract::Forty-four patients with advanced carcinoma of the head and neck were treated with cyclophosphamide, 400 mg/m2 plus BCNU, 100 mg/m2 day 1 followed by adriamycin 40 mg/m2 day 2, with therapy repeated every 4 weeks. Of 31 evaluable patients, there were 1 complete response, and 10 partial responses (35%). Four of 8 patie...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197911)44:5<1571::aid-cncr282044

    authors: Presant CA,Ratkin G,Klahr C,Brown C

    更新日期:1979-11-01 00:00:00

  • Vulvar and vaginal melanoma: A unique subclass of mucosal melanoma based on a comprehensive molecular analysis of 51 cases compared with 2253 cases of nongynecologic melanoma.

    abstract:BACKGROUND:Optimal treatments for vulvar and vaginal melanomas (VVMs) have not been identified. Herein, the authors compare molecular profiles between VVM and nongynecologic melanoma (NGM) subtypes with the objective of identifying novel, targetable biomarkers. METHODS:In total, 2304 samples of malignant melanoma that...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.30473

    authors: Hou JY,Baptiste C,Hombalegowda RB,Tergas AI,Feldman R,Jones NL,Chatterjee-Paer S,Bus-Kwolfski A,Wright JD,Burke WM

    更新日期:2017-04-15 00:00:00

  • Histologic features and clinical significance of venous invasion in colorectal carcinoma with hepatic metastasis.

    abstract:BACKGROUND:In colorectal carcinoma, venous invasion has been related to patient survival. Liver metastasis develops more frequently when venous invasion is present. However, the histologic features and clinical significance of venous invasion are not well understood. METHODS:A histologic study of venous invasion in co...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0142(19961201)78:11<2313::aid-c

    authors: Ouchi K,Sugawara T,Ono H,Fujiya T,Kamiyama Y,Kakugawa Y,Mikuni J,Tateno H

    更新日期:1996-12-01 00:00:00

  • Phase II trial of high-dose, intermittent calcitriol (1,25 dihydroxyvitamin D3) and dexamethasone in androgen-independent prostate cancer.

    abstract:BACKGROUND:Data suggest that vitamin D plays a role in the treatment and prevention of prostate cancer. The combination of high-dose, intermittent calcitriol (1,25 dihydroxyvitamin D3) plus dexamethasone was studied based on evidence that dexamethasone potentiates the antitumor effects of calcitriol and ameliorates hyp...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.21890

    authors: Trump DL,Potter DM,Muindi J,Brufsky A,Johnson CS

    更新日期:2006-05-15 00:00:00

  • Is thyroidectomy necessary in RET mutations carriers of the familial medullary thyroid carcinoma syndrome?

    abstract:BACKGROUND:The results and consequences of genetic testing in a family with familial medullary thyroid carcinoma (FMTC) are described. METHODS:In the screening of relatives, serum calcitonin is replaced by RET mutation analysis that was performed in families suspected of hereditary medullary thyroid carcinoma (MTC). I...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:

    authors: Hansen HS,Torring H,Godballe C,Jäger AC,Nielsen FC

    更新日期:2000-08-15 00:00:00

  • The coexistence of lymphangiosarcoma and Kaposi's sarcoma in a renal transplant recipient.

    abstract::A case of coexisting lymphangiosarcoma and Kaposi's sarcoma that occurred in a female renal transplant recipient is presented. Both sarcomas were localized to the skin and were slowly progressive over several years. The coexistence of these two sarcomas may indicate that they arose from a common precursor endothelial ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19911115)68:10<2330::aid-cncr282

    authors: Studniberg HM,Rivers JK,Cooke BE,Barnetson RS

    更新日期:1991-11-15 00:00:00

  • The use of CEA as an early indicator for gastrointestinal tumor recurrence and second-look procedures.

    abstract::Since 1972 plasma CEA levels of 25 cancer patients have been assayed to evaluate the reliability of CEA as an early indicator of recurrent gastrointestinal cancer. Identification of significant elevations in CEA levels required definition of exactly what a given value meant. Intraassay and interassay accuracy was dete...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197702)39:2<440::aid-cncr2820390

    authors: Martin EW Jr,James KK,Hurtubise PE,Catalano P,Minton JP

    更新日期:1977-02-01 00:00:00

  • Immunohistologic detection of lymphocyte subpopulations infiltrating in human oral cancer with special reference to its clinical significance.

    abstract::Cancer tissues from 30 patients with squamous cell carcinoma of the oral cavity were examined immunohistopathologically as to the responsiveness of the host against its own cancer cells in both biopsy and surgically resected specimens from the same patients. Subpopulations of the infiltrating lymphocytes in cancer tis...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19840601)53:11<2456::aid-cncr282

    authors: Hiratsuka H,Imamura M,Ishii Y,Kohama G,Kikuchi K

    更新日期:1984-06-01 00:00:00

  • Expression of bone morphogenetic proteins in human osteosarcoma. Immunohistochemical detection with monoclonal antibody.

    abstract:BACKGROUND:Bone morphogenetic proteins (BMP) induce ectopic bone formation in vivo and may play a role in normal bone development. In addition, bone morphogenetic activity, as measured in a bone-forming assay in immunodeficient, athymic nu/nu mice, is present in a proportion of osteosarcomas; this activity, which may b...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19940101)73:1<85::aid-cncr282073

    authors: Yoshikawa H,Rettig WJ,Takaoka K,Alderman E,Rup B,Rosen V,Wozney JM,Lane JM,Huvos AG,Garin-Chesa P

    更新日期:1994-01-01 00:00:00