Principles of early detection of cancer.

abstract：:The difficulties encountered in establishing a diagnosis of a malignant peritoneal mesothelioma are emphasized in a patient who developed the lesion 16 years after radiation therapy for a seminoma of the testis. Historically, histologically, electron microscopically, and by microincineration, there was no evidence of ...

journal_title：Cancer

authors： Stock RJ,Fu YS,Carter JR

更新日期：1979-09-01 00:00:00

abstract：:Because chronic lymphocytic leukemia is a heterogeneous disease, there are considerable efforts underway to develop increasingly accurate and precise analytics with which to estimate the probability of future events such as the need for and probability of response to therapy, progression-free survival, and survival. T...

journal_title：Cancer

authors： Montserrat E,Gale RP

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Lesions that contain abundant myoepithelial cells may present as a diagnostic challenge in fine-needle aspiration (FNA) specimens. Potential diagnostic problems may arise due to morphologic heterogeneity of myoepithelial cell-rich lesions and difficulty in predicting malignancy in FNA specimens. An accurate ...

journal_title：Cancer

authors： Darvishian F,Lin O

更新日期：2004-12-25 00:00:00

abstract：:This article reports on the diagnostic features, radiographic findings, staging, operative management, treatments, and treatment results for 95 children (mean age, 10 years) with paratesticular sarcoma; they were treated on the Intergroup Rhabdomyosarcoma Study (IRS) I and II protocols. Embryonal rhabdomyosarcoma (RMS...

journal_title：Cancer

authors： Raney RB Jr,Tefft M,Lawrence W Jr,Ragab AH,Soule EH,Beltangady M,Gehan EA

更新日期：1987-11-01 00:00:00

abstract：BACKGROUND:Screening colonoscopy (SC) for colorectal cancer (CRC) is underused by Latino individuals. The current randomized clinical trial examined the impact of 3 interventions: 1) patient navigation; 2) patient navigation plus standard Centers for Disease Control and Prevention print materials; and 3) patient naviga...

journal_title：Cancer

authors： DuHamel KN,Schofield EA,Villagra C,Sriphanlop P,Itzkowitz SH,Cotter G,Cohen N,Erwin DO,Winkel G,Thompson HS,Zauber AG,Jandorf LH

更新日期：2020-02-15 00:00:00

abstract：BACKGROUND:Approximately 30-50% of patients with myelofibrosis with myeloid metaplasia (MMM) demonstrate detectable cytogenetic abnormalities, the prognostic value of which has not been completely defined by previous retrospective studies. The current prospective study addresses this issue in the context of currently a...

journal_title：Cancer

authors： Tefferi A,Dingli D,Li CY,Dewald GW

更新日期：2005-10-15 00:00:00

abstract：BACKGROUND:The echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK) fusion gene resulting from the chromosome inversion inv(2)(p21;p23) recently was identified in nonsmall cell lung cancer (NSCLC). The authors of this study investigated the frequency, genetic and clinicopathologic prof...

journal_title：Cancer

authors： Wong DW,Leung EL,So KK,Tam IY,Sihoe AD,Cheng LC,Ho KK,Au JS,Chung LP,Pik Wong M,University of Hong Kong Lung Cancer Study Group.

更新日期：2009-04-15 00:00:00

abstract：:Twenty-nine patients treated with adjuvant chemotherapy for carcinoma of the breast were evaluated for frequency and amount of weight gained during treatment. No difference with respect to age, menopausal status, estrogen receptor status, nodal status, biochemical parameters, or treatment regimen (CMF versus CMFVP) we...

journal_title：Cancer

authors： Huntington MO

更新日期：1985-08-01 00:00:00

abstract：:The incidence of long thoracic nerve palsy after radical mastectomy has been documented to be approximately 10%. No cases have been reported after the more recent treatment for breast cancer, lumpectomy with axillary dissection. This more recent surgical procedure is customarily followed by aggressive radiation therap...

journal_title：Cancer

authors： Pugliese GN,Green RF,Antonacci A

更新日期：1987-09-15 00:00:00

abstract：BACKGROUND:Radiation recall refers to a tissue reaction produced by a chemotherapeutic agent in a previously irradiated field that would not occur in a nonirradiated field. A number of agents have been reported to cause radiation recall. Recently, there have been case reports of recall dermatitis from paclitaxel treatm...

journal_title：Cancer

authors： Schweitzer VG,Juillard GJ,Bajada CL,Parker RG

更新日期：1995-09-15 00:00:00

abstract：:Based on laboratory studies showing enhanced cytotoxicity of floxuridine (FUDR) when used with high doses of leucovorin (LV), a pilot study of FUDR and LV through an implantable pump was initiated for the treatment of hepatic metastases from colorectal cancer. The highest dose of LV that could be administered, taking ...

journal_title：Cancer

authors： Kemeny N,Cohen A,Bertino JR,Sigurdson ER,Botet J,Oderman P

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:Ovarian dysplasia has been defined by histologic and morphometric studies focusing on architectural and nuclear profile changes. A new technique is used to enhance the accuracy of this diagnosis by a quantitative evaluation of the nuclear texture that represents the nuclear chromatin pattern on which convent...

journal_title：Cancer

authors： Deligdisch L,Miranda C,Barba J,Gil J

更新日期：1993-12-01 00:00:00

abstract：:Temporary neurologic abnormalities were detected in 9 of 60 patients undergoing treatment with high-dose methotrexate and citrovorum factor rescue (MTX-CF) for osteosarcoma. The incidence of abnormalities and abnormalities themselves were more severe than previously reported. This was attributed to an increased dose a...

journal_title：Cancer

authors： Jaffe N,Takaue Y,Anzai T,Robertson R

更新日期：1985-09-15 00:00:00

abstract：BACKGROUND:The authors performed a case-control analysis of local control, progression free survival, and overall survival in patients with Stage I-II aggressive lymphomas measuring > or = 7 cm in greatest dimension who were treated initially with or without surgical debulking: All patients then received cyclophosphami...

journal_title：Cancer

authors： Wilder RB,Romaguera JE,Tucker SL,Ha CS,Hess MA,Cabanillas F,Cox JD

更新日期：2002-02-01 00:00:00

abstract：:The first three well-documented cases of pure, extraskeletal telangiectatic osteosarcoma of the soft tissues are presented in this article. The distinctive gross features were a predominance of large, blood-filled spaces, which, on histologic examination, were large blood-filled cavities in association with cyst-like ...

journal_title：Cancer

authors： Mirra JM,Fain JS,Ward WG,Eckardt JJ,Eilber F,Rosen G

更新日期：1993-05-15 00:00:00

abstract：:The current study determines the prognostic factors after hepatectomy for hepatocellular carcinomas. The 295 patients who underwent hepatectomy from 1973 through 1987 were included for a univariate and a Cox multivariate analysis. The favoring conditions were determined as follows. The essential requirements are (1) t...

journal_title：Cancer

authors： Yamanaka N,Okamoto E,Toyosaka A,Mitunobu M,Fujihara S,Kato T,Fujimoto J,Oriyama T,Furukawa K,Kawamura E

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:Metastasectomy is standard of care for pediatric patients with metastatic sarcoma with limited disease. For patients with unresectable disease, stereotactic body radiotherapy (SBRT) may serve as an alternative. Herein, the authors report the results of a prospective, multi-institutional phase 2 trial of SBRT...

journal_title：Cancer

authors： Elledge CR,Krasin MJ,Ladra MM,Alcorn SR,Han P,Gibbs IC,Hiniker SM,Laack NN,Terezakis SA

更新日期：2020-11-10 00:00:00

abstract：:Histologic examination of bone-marrow from the posterior iliac crest was routinely done as a pretreatment staging procedure in 203 consecutive patients with small-cell anaplastic carcinoma of the lung. Subtyping of the patients according to the WHO classification included 27.8% with "fusiform" cell type (WHO II,1), 28...

journal_title：Cancer

authors： Hirsch F,Hansen HH,Dombernowsky P,Hainau B

更新日期：1977-06-01 00:00:00

abstract：:Three children with ALL having poor prognostic features developed clinical and laboratory evidence of disseminated intravascular coagulation (DIC). Two developed a bleeding diathesis associated temporally with a rapid drop in blast cell counts during induction therapy with L-asparaginase, prednisone, and vincristine. ...

journal_title：Cancer

authors： Champion LA,Luddy RE,Schwartz AD

更新日期：1978-04-01 00:00:00

abstract：BACKGROUND:Cancer and its treatment lead to increased financial distress for patients. To the authors' knowledge, to date, no standardized patient-reported outcome measure has been validated to assess this distress. METHODS:Patients with AJCC Stage IV solid tumors receiving chemotherapy for at least 2 months were recr...

journal_title：Cancer

authors： de Souza JA,Yap BJ,Wroblewski K,Blinder V,Araújo FS,Hlubocky FJ,Nicholas LH,O'Connor JM,Brockstein B,Ratain MJ,Daugherty CK,Cella D

更新日期：2017-02-01 00:00:00

abstract：:A randomized study was designed to determine the effect of intermittent oral cyclophosphamide on the rate of metastases in children with localized and regional neuroblastoma. Secondary objectives of the study were to determine the value of the proposed staging system, to measure the influence of the peripheral lymphoc...

journal_title：Cancer

authors： Evans AE,Albo V,D'Angio GJ,Finklestein JZ,Leiken S,Santulli T,Weiner J,Hammond GD

更新日期：1976-08-01 00:00:00

abstract：:Ten patients with metastatic osteosarcoma were treated at the Joint Center for Radiation Therapy, the Sidney Farber Cancer Institute, and the Children's Hospital Medical Center from 1973 to 1976. Patients were treated with an aggressive multimodality approach with included surgery, chemotherapy, and radiation therapy....

journal_title：Cancer

authors： Weichselbaum RR,Cassady JR,Jaffe N,Filler RM

更新日期：1977-07-01 00:00:00

abstract：:The authors retrospectively reviewed 50 episodes of spinal epidural tumor that occurred in 42 patients with metastatic prostate cancer and were treated with external-beam radiation. Treatment response was evaluated in terms of symptoms, neurologic status, and, in most cases, reduction of tumor on repeat myelography. A...

journal_title：Cancer

authors： Zelefsky MJ,Scher HI,Krol G,Portenoy RK,Leibel SA,Fuks ZY

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:Cervical carcinoma remains a significant health risk for the older woman. In the current study the yield of screening of mature women in an established, opportunistic screening program was examined. Strategies for improving screening in this age group were identified through examination of recent Pap test hi...

journal_title：Cancer

authors： Colgan TJ,Clarke A,Hakh N,Seidenfeld A

更新日期：2002-08-25 00:00:00

abstract：:Neuroendocrine small cell carcinoma is a lethal, but rare, tumor that arises most frequently in the lung. Small cell cancer also rarely may occur in the female genital tract, usually in the cervix. This article concerns the fourth reported case of neuroendocrine small cell carcinoma of the vulva. Previously, small cel...

journal_title：Cancer

authors： Cliby W,Soisson AP,Berchuck A,Clarke-Pearson DL

更新日期：1991-05-01 00:00:00

abstract：METHODS:The diagnostic performance of transrectal ultrasound (TRUS) gland volume and prostate specific antigen (PSA) results were evaluated in 204 men consecutively scheduled to undergo transurethral prostatic resection (TUR). RESULTS:Nonpalpable prostate cancer was detected by TRUS alone in 18% (29 of 161) and by TUR...

journal_title：Cancer

authors： Lee F,Littrup PJ,Loft-Christensen L,Kelly BS Jr,McHugh TA,Siders DB,Mitchell AE,Newby JE

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:Postgastrectomy patients undergoing chemoradiation risk chemoradiation-induced liver disease (CRILD). The objectives of this study were to investigate dosimetric implications and assess biologic susceptibility to CRILD in these patients. METHODS:Sixty-two patients with Stage IB-IV gastric/gastroesophageal a...

journal_title：Cancer

authors： Cheng JC,Liu MC,Tsai SY,Fang WT,Jer-Min Jian J,Sung JL

更新日期：2004-11-01 00:00:00

abstract：:Twenty-three leukemic children were studied prospectively to detect chronic effects of therapy. All patients received CNS prophylaxis, including 2400 R cranial irradiation, and intermittent maintenance therapy with intravenous methotrexate, cyclophosphamide and cytosine arabinoside. Neurologic symptoms were observed i...

journal_title：Cancer

authors： McIntosh S,Klatskin EH,O'Brien RT,Aspnes GT,Kammerer BL,Snead C,Kalavsky SM,Pearson HA

更新日期：1976-02-01 00:00:00

abstract：BACKGROUND:Chemoradiation with 5-fluorouracil and mitomycin remains the standard of care for squamous cell carcinoma (SCC) of the anal canal. A prolonged treatment time is associated with inferior disease-specific outcomes. Radiation Therapy Oncology Group trial 0529 demonstrated decreased toxicity and fewer treatment ...

journal_title：Cancer

authors： Elson JK,Kachnic LA,Kharofa JR

更新日期：2018-11-15 00:00:00

abstract：:It is justifiable to assume that a spontaneous regression of cervical intraepithelial neoplasia is in progress when pathologic epithelium is replaced by normal epithelium. Very rare histologic pictures of this process are shown. Dysplastic squamous epithelium or intraepithelial carcinomas become detached from their ba...

journal_title：Cancer

authors： Bajardi F

更新日期：1984-08-15 00:00:00