Radiation recall dermatitis and pneumonitis in a patient treated with paclitaxel.

abstract：:Chemotherapy of advanced stages of large bowel cancer has until recently made little progress since the introduction of 5-FU 16 years ago. While survival is improved for patients who respond, 5-FU alone has made little impact on life span of the overall population of patients. Mitomycin-C and the chloroethyl nitrosour...

journal_title：Cancer

authors： Schein PS,Kisner D,MacDonald JS

更新日期：1975-12-01 00:00:00

abstract：BACKGROUND:Between January 11, 1991 and January 8, 1992, 104 patients with previously untreated, invasive, primitive breast carcinoma were admitted to the authors' hospital. METHODS:For each patient, flow cytometry DNA analyses on frozen samples and on immunohistochemical staining were performed, including Ki-67, cycl...

journal_title：Cancer

authors： Michels JJ,Duigou F,Marnay J,Henry-Amar M,Delozier T,Denoux Y,Chasle J

更新日期：2003-03-15 00:00:00

abstract：BACKGROUND:The ability to divide subsets of patients with glial neoplasms into prognostic groups currently is limited because only a few clinical and pathologic variables are available. The goal of this investigation was to identify biologic factors of potential prognostic value in patients with cerebral gliomas. METH...

journal_title：Cancer

authors： Ganju V,Jenkins RB,O'Fallon JR,Scheithauer BW,Ransom DT,Katzmann JA,Kimmel DW

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:The overexpression of HER-2 occurs in a minority of patients with nonsmall cell lung carcinoma. Trastuzumab, which is a monoclonal antibody to HER-2, is an effective treatment in some women with breast carcinomas that overexpress HER-2, as demonstrated by immunohistochemistry. The objective of this Phase II ...

journal_title：Cancer

authors： Clamon G,Herndon J,Kern J,Govindan R,Garst J,Watson D,Green M,Cancer and Leukemia Group B.

更新日期：2005-04-15 00:00:00

abstract：:This study delineates the temporal relationship between immune complex formation and tumor growth, and provides one possible explanation for host immunosuppression during tumor growth. The authors have studied serial circulating immune complex (CIC) levels and interleukin (IL) elaboration by peripheral blood cells (IL...

journal_title：Cancer

authors： Ravikumar T,Steele G Jr,Rodrick M,Ross D,Wilson R,Lahey S,Wright D,Munroe A,King V

更新日期：1984-03-15 00:00:00

abstract：BACKGROUND:It is challenging for clinicians to foster coping and allow hope when discussing prognosis and end-of-life (EOL) issues with terminally ill cancer patients and their caregivers. To the authors' knowledge, little research evidence is currently available to guide clinical practice. METHODS:The authors conduct...

journal_title：Cancer

authors： Clayton JM,Butow PN,Arnold RM,Tattersall MH

更新日期：2005-05-01 00:00:00

abstract：:Therapy for acute lymphocytic leukemia (ALL) has been less successful in adults than in children. Many centers treat all adult leukemia with the same regimen. We have used vincristine and prednisone for initial therapy in 14 adults with ALL since 1971 and have followed a treatment regimen developed for childhood ALL f...

journal_title：Cancer

authors： Scavino HF,George JN,Sears DA

更新日期：1976-08-01 00:00:00

abstract：BACKGROUND:Inactivation of the tumor suppressor gene PTEN/MMAC1/TEP1, located on chromosome 10q23, is a common event in advanced stages of diverse human malignancies. However, the prognostic role of PTEN expression in patients with hepatocellular carcinoma (HCC) has not been characterized. METHODS:One hundred five res...

journal_title：Cancer

authors： Hu TH,Huang CC,Lin PR,Chang HW,Ger LP,Lin YW,Changchien CS,Lee CM,Tai MH

更新日期：2003-04-15 00:00:00

abstract：:Two unusual cases of angioimmunoblastic lymphadenopathy with dysproteinemia (AILD), with progression to immunoblastic lymphoma (IL) and prominent gastric involvement are presented, and detailed immunohistologic studies described. In one case, Bence Jones proteinuria of the kappa type was observed during the course of ...

journal_title：Cancer

authors： Bauer TW,Mendelsohn G,Humphrey RL,Mann RB

更新日期：1982-11-15 00:00:00

abstract：:Results of cytogenetic studies of a patient with acute granulocytic leukemia are described. The modal number of chromosomes in cells from bone marrow samples was 43; the karyotype was characterized by missing chromosomes in groups B, C, and E. According to successive studies of the same metaphases by fluorescent stain...

journal_title：Cancer

authors： Sofuni T,Okada H

更新日期：1975-02-01 00:00:00

abstract：BACKGROUND:In addition to tumor thickness, several other prognostic parameters have been identified in primary human melanomas. Some are available readily (localization, gender, age, and ulceration). Others must be evaluated with a moderate or even substantial amount of work (mitoses and immunohistochemical markers). T...

journal_title：Cancer

authors： Ostmeier H,Fuchs B,Otto F,Mawick R,Lippold A,Krieg V,Suter L

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:Arthralgia is common in postmenopausal breast cancer survivors (BCS) who are receiving aromatase inhibitors (AIs). The objective of this study was to evaluate the perceived onset, characteristics, and risk factors for AI-related arthralgia (AIA). METHODS:In a cross-sectional survey of postmenopausal BCS who...

journal_title：Cancer

authors： Mao JJ,Stricker C,Bruner D,Xie S,Bowman MA,Farrar JT,Greene BT,DeMichele A

更新日期：2009-08-15 00:00:00

abstract：BACKGROUND:This retrospective analysis examines the frequency, distribution, and the pattern of disease progression of bone metastasis in patients treated for cervical cancer and the use and results of palliative intent radiation therapy. METHODS:Charts, films, and other available records were reviewed for the 41 pati...

journal_title：Cancer

authors： Ratanatharathorn V,Powers WE,Steverson N,Han I,Ahmad K,Grimm J

更新日期：1994-05-01 00:00:00

abstract：:In 95 surgically staged patients with squamous cell carcinoma of the maxillary sinus, multivariate regression analyses were employed to identify prognostic factors. Possible prognostic factors for local control were TNM stage and type of surgical procedures: T2 or T3 tumors and use of total maxillectomy showed better ...

journal_title：Cancer

authors： Kondo M,Ogawa K,Inuyama Y,Yamashita S,Tominaga S,Shigematsu N,Nishiguchi I,Hashimoto S

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:The role of the interaction between tumor cells and inflammatory cells in nonsmall cell lung carcinoma (NSCLC) is unclear. In this study, the authors assessed the prognostic impact of intratumoral cluster of differentiation 66b (carcinoembryonic antigen-related cell adhesion molecule 8 [CD66b])-positive neut...

journal_title：Cancer

authors： Ilie M,Hofman V,Ortholan C,Bonnetaud C,Coëlle C,Mouroux J,Hofman P

更新日期：2012-03-15 00:00:00

abstract：:A short-term differential staining cytotoxicity (DiSC) assay was used to assess the sensitivity of tumor cells in vitro from patients with chronic lymphocytic leukemia (CLL) and non-Hodgkin's lymphoma to various cytotoxic drugs. The results have been correlated with drug sensitivities of the tumors in vivo. The chemos...

journal_title：Cancer

authors： Bird MC,Bosanquet AG,Forskitt S,Gilby ED

更新日期：1988-03-15 00:00:00

abstract：BACKGROUND:During hospitalization for hematopoietic stem cell transplantation (HCT), patients experience a steep deterioration in quality of life (QOL) and mood. To our knowledge, the impact of this deterioration on patients' QOL and posttraumatic stress disorder (PTSD) symptoms after HCT is unknown. METHODS:We conduc...

journal_title：Cancer

authors： El-Jawahri AR,Vandusen HB,Traeger LN,Fishbein JN,Keenan T,Gallagher ER,Greer JA,Pirl WF,Jackson VA,Spitzer TR,Chen YB,Temel JS

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:The objective of this study was to define the effects of socioeconomic status (SES) and other demographic variables on outcomes for patients with pancreatic adenocarcinoma. METHODS:Florida cancer registry and inpatient hospital data were queried for pancreatic adenocarcinoma diagnosed from 1998 to 2002. RE...

journal_title：Cancer

authors： Cheung MC,Yang R,Byrne MM,Solorzano CC,Nakeeb A,Koniaris LG

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Monoclonal antibodies have not been evaluated in metastasizing endocrine tumors, even though these lesions may induce severe morbidity of hormone excess in absence of considerable tumor burden. METHODS:A murine monoclonal antibody of the IgG2a subtype was generated by immunization with dispersed tumor cells...

journal_title：Cancer

authors： Juhlin C,Papanicolaou V,Arnberg H,Klareskog L,Lörelius LE,Rastad J,Oberg K,Akerström G

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND:Apricoxib, a novel once-daily selective cyclooxygenase-2 inhibitor, was investigated in combination with erlotinib for recurrent stage IIIB/IV nonsmall cell lung cancer to determine the maximum tolerated dose, dose-limiting toxicity, and recommended phase II dose (RP2D) based on changes in urinary prostaglan...

journal_title：Cancer

authors： Reckamp K,Gitlitz B,Chen LC,Patel R,Milne G,Syto M,Jezior D,Zaknoen S

更新日期：2011-02-15 00:00:00

abstract：:Several decades ago, it was reported that normal and malignant mesothelial cells were transformed into distinct cell types (epithelial to fibrous and fibrous to epithelial) when transferred to in vitro conditions. Those tissue culture data are still cited as evidence supporting that the mesothelial cell has multipoten...

journal_title：Cancer

authors： Suzuki Y,Chahinian AP,Ohnuma T

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND:Introduction of human papillomavirus (HPV) vaccination for adolescent girls is being considered in the Punjab state of India. However, evidence regarding cost-effectiveness is sought by policy makers when making this decision. The current study was undertaken to evaluate the incremental cost per quality-adju...

journal_title：Cancer

authors： Prinja S,Bahuguna P,Faujdar DS,Jyani G,Srinivasan R,Ghoshal S,Suri V,Singh MP,Kumar R

更新日期：2017-09-01 00:00:00

abstract：:The unique case of a 60-year-old patient with a non-Hodgkin's B-cell lymphoma of the lymphoplasmacytic type and three associated monoclonal proteins, is described. The patient also exhibited various autoimmune phenomena that were consistent with the diagnoses of Sjögren's syndrome and autoimmune thyroiditis. The evolu...

journal_title：Cancer

authors： Berg AR,Weisenburger DD,Linder J,Armitage JO

更新日期：1986-05-01 00:00:00

abstract：BACKGROUND:The intraoperative evaluation of axillary sentinel lymph nodes (SLNs) allows the surgeon to complete axillary dissection in 1 setting at the time of the primary breast surgery. However, to the authors' knowledge, there is no consensus regarding the optimal method for intraoperative evaluation of SLNs in brea...

journal_title：Cancer

authors： Krishnamurthy S,Meric-Bernstam F,Lucci A,Hwang RF,Kuerer HM,Babiera G,Ames FC,Feig BW,Ross MI,Singletary E,Hunt KK,Bedrosian I

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Heparanase up-regulation has been correlated with reduced postoperative survival in various cancers. METHODS:Heparanase expression was analyzed in 60 consenting tongue (mobile) cancer patients by means of immunohistochemistry. Heparanase levels were also analyzed in the saliva of both healthy controls and t...

journal_title：Cancer

authors： Nagler R,Ben-Izhak O,Cohen-Kaplan V,Shafat I,Vlodavsky I,Akrish S,Ilan N

更新日期：2007-12-15 00:00:00

abstract：:Unraveling cancer-associated molecular defects is crucial for further pharmacological targeting. Although novel techniques are being developed to elucidate genomic, proteomic, and transcriptomic alterations, the map of protein interactions and aberrations in normal but also in malignant cells is still obscure. It has ...

journal_title：Cancer

authors： Karamouzis MV,Papavassiliou AG

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Age-related disparities in colon cancer treatment exist, with older patients being less likely to receive recommended therapy. However, to the authors' knowledge, few studies to date have focused on receipt of surgery. The objective of the current study was to describe patterns of surgery in patients aged ≥ ...

journal_title：Cancer

authors： Neuman HB,O'Connor ES,Weiss J,Loconte NK,Greenblatt DY,Greenberg CC,Smith MA

更新日期：2013-02-01 00:00:00

abstract：:The diagnosis of malignant melanoma is based on clinical grounds and a properly performed biopsy, preferably excision, so that the type of melanoma and the thickness can be assessed by methods described by Clark and Breslow. These facilitate clinical and pathologic staging. Excisions with conservative margins for thin...

journal_title：Cancer

authors： Harris MN,Shapiro RL,Roses DF

更新日期：1995-01-15 00:00:00

abstract：BACKGROUND:Outcomes for patients with relapsed/refractory acute myeloid leukemia (R/R AML) remain poor. Novel therapies specifically targeting AML are of high interest. Brentuximab vedotin (BV) is an antibody-drug conjugate that is specific for human CD30. In this phase 1 dose escalation study, the authors evaluated th...

journal_title：Cancer

authors： Narayan R,Blonquist TM,Emadi A,Hasserjian RP,Burke M,Lescinskas C,Neuberg DS,Brunner AM,Hobbs G,Hock H,McAfee SL,Chen YB,Attar E,Graubert TA,Bertoli C,Moran JA,Bergeron MK,Foster JE,Ramos AY,Som TT,Vartanian MK,

更新日期：2020-03-15 00:00:00

abstract：:Adenoid cystic carcinoma of the esophagus is a relatively rare lesion which characteristically exhibits a clinically aggressive behavior. In spite of this aggressive nature, it is most often referred to as a counterpart of the more common adenoid cystic carcinoma of salivary gland origin, a comparatively indolent tumo...

journal_title：Cancer

authors： Epstein JI,Sears DL,Tucker RS,Eagan JW Jr

更新日期：1984-03-01 00:00:00