Long-term comparison of results of a drug sensitivity assay in vitro with patient response in lymphatic neoplasms.

abstract：BACKGROUND:Second primary tumors are a leading cause of death among patients with head and neck cancer; therefore, early detection of these tumors is necessary. In the current study, the authors aimed to evaluate the diagnostic capacity of (18)F-fluorodeoxyglucose dual-head positron emission tomography (FDG-PET) for de...

journal_title：Cancer

authors： Stokkel MP,Moons KG,ten Broek FW,van Rijk PP,Hordijk GJ

更新日期：1999-12-01 00:00:00

abstract：:The woman treated for gynecologic cancer must contend with a challenging group of issues in her efforts to recover psychologically in the months and years after treatment: chance of dying, changed self-perception, treatment-related menopause, impaired or lost fertility, sexual dysfunction, and relationship problems mu...

journal_title：Cancer

authors： Auchincloss SS

更新日期：1995-11-15 00:00:00

abstract：BACKGROUND:Meticulous selection of patients for esophageal cancer surgery is critical, because major surgical intervention can cause considerable consequences. For this study, the authors explored their institution's large surgical experience to examine the impact of age on long-term patient survival and surgical compl...

journal_title：Cancer

authors： Braiteh F,Correa AM,Hofstetter WL,Rice DC,Vaporciyan AA,Walsh GL,Roth JA,Mehran RJ,Swisher SG,Ajani JA

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:The objective of this analysis was to evaluate the role of autologous stem cell transplantation (ASCT) in prolonging disease free survival (DFS) and overall survival (OS) in patients with chronic myeloid leukemia (CML) who received autografts of Philadelphia chromosome (Ph) positive or Ph negative cell harve...

journal_title：Cancer

authors： Koziner B,Dengra C,Lucero G,Klein G,Cánepa C,Milovic V,Milone G,Robinson A,Cerutti I,Saporito G,Kusminsky G,Milone J,Bordone J,Lastiri F,Argentine Group of Bone Marrow Transplantation.

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:Hyperglycemia is often observed in medically ill patients. Previous studies have shown that patients with hyperglycemia during induction therapy for acute lymphoblastic leukemia develop more infections and have shorter disease-free survival. The authors hypothesized that hyperglycemia may be associated with ...

journal_title：Cancer

authors： Ali NA,O'Brien JM Jr,Blum W,Byrd JC,Klisovic RB,Marcucci G,Phillips G,Marsh CB,Lemeshow S,Grever MR

更新日期：2007-07-01 00:00:00

abstract：:The growth rates of recurrent hepatocellular carcinoma (HCC) after orthotopic liver transplantation (OLTX) were estimated by calculating the tumor doubling time (TDT) in 20 patients. The mean TDT, calculated by multiple measurement of tumor size, was 44.3 +/- 11.3 days (mean +/- standard error) in 12 patients with pul...

journal_title：Cancer

authors： Yokoyama I,Carr B,Saitsu H,Iwatsuki S,Starzl TE

更新日期：1991-11-15 00:00:00

abstract：:Forty-one previously untreated patients with a diagnosis of acute myelogenous leukemia (AML) were entered on a study using early intensification followed by a short-term maintenance chemotherapy. Induction and early intensification consisted of three to four cycles of doxorubicin, vincristine, cytosine arabinoside (Ar...

journal_title：Cancer

authors： Kantarjian HM,Keating MJ,Walters RS,McCredie KB,Bodey GP,Freireich EJ

更新日期：1986-10-15 00:00:00

abstract：BACKGROUND:This article reviews the salient pathologic and clinical features of 171 patients with Stage III-IV disease who were 60 years of age or older who were treated on four Hodgkin disease (HD) protocols from 1969 to 1988. METHODS:Pretherapy sections were reviewed centrally for correlation of the histologic class...

journal_title：Cancer

authors： Mir R,Anderson J,Strauchen J,Nissen NI,Cooper MR,Rafla S,Canellos GP,Bloomfield CD,Gottlieb AJ,Peterson B

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND:Wild-type p53 protein activates the WAF1/CIP-1 (p21) gene, leading to G1 arrest after DNA damage. The authors investigated the relation of p21 and p53 expression in pancreatic adenocarcinomas to disease stage, overall patient survival, and survival when chemotherapy or radiation therapy was given. METHODS:P...

journal_title：Cancer

authors： Dergham ST,Dugan MC,Joshi US,Chen YC,Du W,Smith DW,Arlauskas P,Crissman JD,Vaitkevicius VK,Sarkar FH

更新日期：1997-08-01 00:00:00

abstract：:The authors present a retrospective review of 90 cases of Stage III endometrial carcinoma seen over a 10-year period at the Princess Margaret Hospital, Toronto. Overall 5-year survival was 45.5% and disease-free survival was 36.0%. Prognostic factors identified within Stage III were tumor grade, geographic distributio...

journal_title：Cancer

authors： Mackillop WJ,Pringle JF

更新日期：1985-11-15 00:00:00

abstract：BACKGROUND:The importance of the bone marrow microenvironment in multiple myeloma is receiving increasing attention. Recent studies have suggested the importance of cytokine production and cell-cell contact by bone marrow stromal cells in the survival of myeloma cells. METHODS:In the current study, the authors examine...

journal_title：Cancer

authors： Wallace SR,Oken MM,Lunetta KL,Panoskaltsis-Mortari A,Masellis AM

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:Plasma acidic glutathione S-transferase (GST-pi) concentrations in 135 patients with gastrointestinal cancer were measured by an improved radioimmunoassay (RIA). METHODS:Blood was collected into a silicified glass tube containing a specific anticoagulant. The plasma, which was separated rapidly by centrifug...

journal_title：Cancer

authors： Fan KC,Huang YC,Li CH

更新日期：1995-10-15 00:00:00

abstract：BACKGROUND:Children of different racial/ethnic backgrounds have varying risks of cancer. However, to the authors' knowledge, few studies to date have examined cancer occurrence in children of mixed ancestry. METHODS:This population-based case-control study examined cancer among children aged <15 years using linked can...

journal_title：Cancer

authors： Chow EJ,Puumala SE,Mueller BA,Carozza SE,Fox EE,Horel S,Johnson KJ,McLaughlin CC,Reynolds P,Von Behren J,Spector LG

更新日期：2010-06-15 00:00:00

abstract：BACKGROUND:Health insurance is a key mediator of health care disparities. Outcomes in bladder cancer, one of the costliest diseases to treat, may be especially sensitive to a patient's insurance status. METHODS:The Surveillance, Epidemiology, and End Results registry and the National Cancer Data Base were used to iden...

journal_title：Cancer

authors： Fletcher SA,Cole AP,Lu C,Marchese M,Krimphove MJ,Friedlander DF,Mossanen M,Kilbridge KL,Kibel AS,Trinh QD

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Current research is inconclusive regarding the relation between alcohol consumption and prostate cancer risk. In this study, the authors examined the associations of total alcohol, type of alcoholic beverage, and drinking pattern with the risk of total, low-grade, and high-grade prostate cancer. METHODS:Dat...

journal_title：Cancer

authors： Gong Z,Kristal AR,Schenk JM,Tangen CM,Goodman PJ,Thompson IM

更新日期：2009-08-15 00:00:00

abstract：:Tumor weight, carcass weight, nitrogen balance, energy balance, resting energy expenditure (REE), and activity energy expenditure (AEE) were measured in normal Fischer 344 rats, free-feeding Fischer 344 rats with methylcholanthrene-induced sarcoma (TB-FF), and similar tumor-bearing rats supported with total parenteral...

journal_title：Cancer

authors： Popp MB,Brennan MF,Morrison SD

更新日期：1982-03-15 00:00:00

abstract：BACKGROUND:Tyrosine kinase inhibitors (TKIs) of the epidermal growth factor receptor (EGFR) have activity in solid tumors. The authors evaluated an oral EGFR TKI, erlotinib, in patients with previously treated esophageal cancer. METHODS:Thirty patients with measurable, metastatic cancer of the esophageal and gastroeso...

journal_title：Cancer

authors： Ilson DH,Kelsen D,Shah M,Schwartz G,Levine DA,Boyd J,Capanu M,Miron B,Klimstra D

更新日期：2011-04-01 00:00:00

abstract：:The observation, in 1980, of a rapid increase in platelet counts as a result of administration of intravenous immunoglobulin (IVIG) in a patient with immune thrombocytopenic purpura (ITP) was followed by clinical studies confirming the efficacy of this new treatment alternative in ITP. Simultaneously, new sensitive as...

journal_title：Cancer

authors： Imbach P

更新日期：1991-09-15 00:00:00

abstract：:The DNA content of human plasma cells from myeloma patients relative to that of leukocytes was determined by flow and microscopic cytofluorometry after propidium iodide and fluorescent Feulgen staining, respectively. Mononucleated myeloma plasma cells from all of the 17 patients studied contained more DNA (17 to 58%) ...

journal_title：Cancer

authors： Brox L,Mowles D,Pollock B,Belch A

更新日期：1981-05-15 00:00:00

abstract：:In malignant melanoma, using Sephadex G-200 chromatography and polyacrylamide gel electrophoresis (PAGE), it has been possible to separate two types of skin reactive antigens. The first, found in Sephadex fraction II and PAGE region a appears specific for melanoma. Allogeneic extracts have produced positive reactions ...

journal_title：Cancer

authors： Hollinshead AC

更新日期：1975-10-01 00:00:00

abstract：:Plasminogen activator is a serine protease which exists in two forms, known as tissue-type plasminogen activator and urokinase-type plasminogen activator. Here, we show that urokinase-type plasminogen activator activity in primary breast carcinomas correlates with both size of tumor and number of axillary nodes with m...

journal_title：Cancer

authors： Duffy MJ,O'Grady P,Devaney D,O'Siorain L,Fennelly JJ,Lijnen HJ

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND:Parathyroid hormone-related protein (PTHrP) has been shown to be the principal cause of humoral hypercalcemia associated with renal cell carcinoma (RCC). Recent studies have demonstrated that the amino-terminal region of PTHrP has growth factor-like activities, suggesting it may play a role in the developmen...

journal_title：Cancer

authors： Iwamura M,Wu W,Muramoto M,Ohori M,Egawa S,Uchida T,Baba S

更新日期：1999-09-15 00:00:00

abstract：BACKGROUND:False-positive cancer screening results may affect a patient's willingness to obtain future screening. METHODS:The authors conducted logistic regression analysis of 450,484 person-years of electronic medical records (2006-2015) in 92,405 individuals aged 50 to 75 years. Exposures were false-positive breast,...

journal_title：Cancer

authors： Taksler GB,Keating NL,Rothberg MB

更新日期：2018-06-01 00:00:00

abstract：:The results of assay for estrogen receptor (ER) in the tumor cytosol and thymidine labeling indices (TLI) of 63 primary invasive carcinomas of the breast were analyzed. The ER assay was performed by using dextran-charcoal to adsorb unbound tritiated estradiol-17beta (E2) in cytosol. The TLI was measured as the number ...

journal_title：Cancer

authors： Meyer JS,Rao BR,Stevens SC,White WL

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND:Gastric carcinoids are uncommon, and are unlike carcinoids at other gastrointestinal sites, clinically and pathologically. METHODS:The authors studied specimens from 104 patients with gastric carcinoid, with study emphasis being placed on pathologic features, immunohistochemistry, clinical associations, and...

journal_title：Cancer

authors： Thomas RM,Baybick JH,Elsayed AM,Sobin LH

更新日期：1994-04-15 00:00:00

abstract：:Forty-nine specimens of carcinoma of the breast were analyzed for estrogen receptor content using the sucrose gradient method and a histochemical method using a conjugate of estradiol (6-BSA-Fluor-CMO-17 beta-estradiol). The specimens analyzed by the histochemical method were graded for fluorescent intensity, percenta...

journal_title：Cancer

authors： Panko WB,Mattioli CA,Wheeler TM

更新日期：1982-05-15 00:00:00

abstract：:Six patients with lymphomatoid granulomatosis were studied. Two patients had eye involvement, a rare manifestation of this disease. Both had complete disappearance of disease in this area after radiation therapy. One patient presented with an autoimmune hemolytic anemia, which remitted completely with chemotherapy. Th...

journal_title：Cancer

authors： Sordillo PP,Epremian B,Koziner B,Lacher M,Lieberman P

更新日期：1982-05-15 00:00:00

abstract：BACKGROUND:Early-phase trials in patients with recurrent neuroblastoma historically used an objective "response" of measureable disease (Response Evaluation Criteria In Solid Tumors [RECIST], without bone/bone marrow assessment) to select agents for further study. Historical cohorts may be small and potentially biased;...

journal_title：Cancer

authors： London WB,Bagatell R,Weigel BJ,Fox E,Guo D,Van Ryn C,Naranjo A,Park JR

更新日期：2017-12-15 00:00:00

abstract：BACKGROUND:Radiologic Diagnostic Oncology Group 5 is a multicenter clinical trial designed to evaluate fine-needle aspiration (FNA) of nonpalpable breast lesions performed by multiple operators using the same protocol. METHODS:Four hundred and nineteen women with mammographically detected nonpalpable breast lesions we...

journal_title：Cancer

authors： Pisano ED,Fajardo LL,Tsimikas J,Sneige N,Frable WJ,Gatsonis CA,Evans WP,Tocino I,McNeil BJ

更新日期：1998-02-15 00:00:00

abstract：:The records were reviewed for all patients hospitalized at a pediatric oncology center for complications of leukemia (n = 822) or lymphoma (n = 290) during an 8-year period. The results of surveillance cultures (throat, rectal, and urine) and blood cultures were analyzed to identify cases of Candida tropicalis and C. ...

journal_title：Cancer

authors： Marina NM,Flynn PM,Rivera GK,Hughes WT

更新日期：1991-08-01 00:00:00