Effects of tumor growth on interleukins and circulating immune complexes. Mechanisms of immune unresponsiveness.

abstract：BACKGROUND:Because angiogenesis may play a role in the pathogenesis of acute myeloid leukemia (AML) and high-risk myelodysplastic syndrome (MDS), and thalidomide (Th) has shown significant anti-angiogenic activity, this study was designed to investigate the potential role of Th in the treatment of patients with AML and...

journal_title：Cancer

authors： Cortes J,Kantarjian H,Albitar M,Thomas D,Faderl S,Koller C,Garcia-Manero G,Giles F,Andreeff M,O'Brien S,Keating M,Estey E

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Older adults are an important audience for smoking cessation programs. Over 4.5 million older adults (older than 65) continue to smoke, and the majority are long term, heavy smokers. There is evidence that smoking cessation programs tailored to older smokers can be effective. American Cancer Society (ACS) ma...

journal_title：Cancer

authors： Rimer BK,Orleans CT

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:Low-dose computed tomography (LDCT) lung screening has been associated with a 20% reduction in lung cancer mortality. A major barrier to the adoption of lung screening is the potential negative psychological impact of a false-positive (FP) screen, occurring in 20% to 50% of those screened. The objective of t...

journal_title：Cancer

authors： Gareen IF,Duan F,Greco EM,Snyder BS,Boiselle PM,Park ER,Fryback D,Gatsonis C

更新日期：2014-11-01 00:00:00

abstract：:Poor drug compliance may cause a decreased survival of children with malignancies. Children who fail to take their medications are not receiving optimum amounts of chemotherapy and suboptimal therapy causes a shortened survival in children with cancer. This is a study of prednisone compliance in 52 children with cance...

journal_title：Cancer

authors： Smith SD,Rosen D,Trueworthy RC,Lowman JT

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND:The Edmonton Symptom Assessment Scale (ESAS) is a nine-item patient-rated symptom visual analogue scale developed for use in assessing the symptoms of patients receiving palliative care. The purpose of this study was to validate the ESAS in a different population of patients. METHODS:In this prospective stu...

journal_title：Cancer

authors： Chang VT,Hwang SS,Feuerman M

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:The aim of this study was to determine if extrapulmonary small cell carcinomas (EPSCC) should be managed using protocols similar to those for small cell lung cancer (SCLC). METHODS:Treatment strategies, survival, patterns of failure, and prognostic factors for patients with EPSCC were analyzed retrospective...

journal_title：Cancer

authors： Brennan SM,Gregory DL,Stillie A,Herschtal A,Mac Manus M,Ball DL

更新日期：2010-02-15 00:00:00

abstract：:A patient is presented who developed a peritoneal malignant mesothelioma in association with severe persistent and recurrent diverticulitis. The case is unusual in that a spectrum of mesothelial proliferation was documented beginning initially as benign foci of mesothelial proliferation and passing through a stage of ...

journal_title：Cancer

authors： Riddell RH,Goodman MJ,Moossa AR

更新日期：1981-07-01 00:00:00

abstract：:The author reviewed the question of late side effects of cancer treatment. A late side effect was defined as an unwanted and deleterious effect observed for the first time 12 months or longer after treatment. In a survey of articles published by The New England Journal of Medicine and The Lancet from 1968 to 1988, nin...

journal_title：Cancer

authors： Boivin JF

更新日期：1990-02-01 00:00:00

abstract：:To determine the impact of pulmonary infections on survival in patients with lung cancer, a retrospective review of the records of 121 such patients treated at Howard University Hospital in Washington, DC, was done. There were 77 men and 44 women; 118 were black. The mean age was 63.5 years. Forty-three patients had s...

journal_title：Cancer

authors： Perlin E,Bang KM,Shah A,Hursey PD,Whittingham WL,Hashmi K,Campbell L,Kassim OO

更新日期：1990-08-01 00:00:00

abstract：BACKGROUND:Angiogenesis is essential for tumor growth, progression, and metastases. Microvessel density (MVD), a measure of tumor angiogenesis, has been found to have prognostic significance in many tumor types for predicting metastasis and survival. METHODS:Between 1979-1989, 56 cases of FIGO Clinical Stage I and II ...

journal_title：Cancer

authors： Kaku T,Hirakawa T,Kamura T,Amada S,Kinukawa N,Kobayashi H,Sakai K,Ariyoshi K,Sonoda K,Nakano H

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:Laryngeal cancer is the primary cause of death among patients with head and neck cancer in Argentina. Different prognostic factors have been incidentally dealt with in a number of articles, but there are few studies of prognostic variables, such as age, tobacco, and alcohol, using multifactorial analysis. M...

journal_title：Cancer

authors： Pradier R,González A,Matos E,Loria D,Adan R,Saco P,Califano L

更新日期：1993-04-15 00:00:00

abstract：:Artificial neural networks now are used in many fields. They have become well established as viable, multipurpose, robust computational methodologies with solid theoretic support and with strong potential to be effective in any discipline, especially medicine. For example, neural networks can extract new medical infor...

journal_title：Cancer

authors： Dayhoff JE,DeLeo JM

更新日期：2001-04-15 00:00:00

abstract：:Intersitial pneumonia and pulmonary fibrosis developed in a 72-year-old man during therapy with cyclophosphamide, vincristine, and prednisone. After extensive investigations, including an open lung biopsy, cyclophosphamide appeared to be the cause of the pulmonary disease. Complete disappearance of tachypnea and the p...

journal_title：Cancer

authors： Patel AR,Shah PC,Rhee HL,Sassoon H,Rao KP

更新日期：1976-10-01 00:00:00

abstract：BACKGROUND:Helicobacter pylori recently was identified as a risk factor for gastric cancer. Its association with preneoplastic conditions of the stomach, however, is undocumented. METHODS:Gastric biopsy specimens from 245 symptomatic patients were examined for neoplastic and preneoplastic lesions and for gastric H. py...

journal_title：Cancer

authors： Guarner J,Mohar A,Parsonnet J,Halperin D

更新日期：1993-01-15 00:00:00

abstract：BACKGROUND:Patient navigation may reduce cancer disparities associated with socioeconomic status (SES) and household factors. This study examined whether these factors were associated with delays in diagnostic resolution among patients with cancer screening abnormalities and whether patient navigation ameliorated these...

journal_title：Cancer

authors： Rodday AM,Parsons SK,Snyder F,Simon MA,Llanos AA,Warren-Mears V,Dudley D,Lee JH,Patierno SR,Markossian TW,Sanders M,Whitley EM,Freund KM

更新日期：2015-11-15 00:00:00

abstract：BACKGROUND:Osteosarcomas are typically long bone tumors and rarely affect the skull, with most articles reporting single cases. As elsewhere in the body, these lesions may be classified as primary or secondary, chiefly post-Paget and post-radiation therapy. METHODS:The authors reviewed the osteosarcomas of the skull d...

journal_title：Cancer

authors： Salvati M,Ciappetta P,Raco A

更新日期：1993-04-01 00:00:00

abstract：:The results of surgical treatment alone for 142 cases of carcinoma of the rectum and rectosigmoid from the Massachusetts General Hospital were reviewed. The incidence of local failure as any component of failure was found to be strongly dependent on the pathologic stage, and for Dukes' A was 8.0% (3/39); Dukes' B, 31%...

journal_title：Cancer

authors： Rich T,Gunderson LL,Lew R,Galdibini JJ,Cohen AM,Donaldson G

更新日期：1983-10-01 00:00:00

abstract：:A 37-year-old woman with a giant, lymphocytic predominant thymoma involving the pleura and accompanied by a sharp peripheral blood lymphocytosis is described. Only electromicroscopic and immunohistologic studies could exclude the alternative diagnosis of mediastinal lymphoma. The tumor and peripheral blood lymphocytes...

journal_title：Cancer

authors： Shachor Y,Radnay J,Bernheim J,Rozenszajn A,Bruderman I,Klajman A,Steiner ZP

更新日期：1988-03-15 00:00:00

abstract：BACKGROUND:Consumers increasingly consult the Internet for breast cancer information. Concerned about accuracy, multiple organizations developed quality criteria for online content. However, the effectiveness of these tools is unknown. The authors determined whether existing quality criteria can identify inaccurate bre...

journal_title：Cancer

authors： Bernstam EV,Walji MF,Sagaram S,Sagaram D,Johnson CW,Meric-Bernstam F

更新日期：2008-03-15 00:00:00

abstract：:One hundred eighty-three patients with malignant skeletal (83) or soft tissue sarcoma (100) were entered into the multimodality preoperative limb salvage protocol. Local recurrences were observed in 5 of 183 (2.7%). Six patients required amputation because of complications, and 13 patients died within 1 year from meta...

journal_title：Cancer

authors： Eilber FR,Morton DL,Eckardt J,Grant T,Weisenburger T

更新日期：1984-06-15 00:00:00

abstract：BACKGROUND:The objective of this study was to assess the impact of a prostate-specific antigen (PSA) complete response (PSA-CR), measured at the end of external-beam radiotherapy and short-term hormone therapy, on treatment outcomes. METHODS:The phase 3 Radiation Therapy Oncology Group 9413 trial, as part of its origi...

journal_title：Cancer

authors： Cury FL,Hunt D,Roach M 3rd,Shipley W,Gore E,Hsu IC,Krisch RE,Seider MJ,Sandler H,Lawton C

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Breast carcinoma commonly metastasizes to the skeleton in patients with advanced disease to cause bone destruction and the associated pain, hypercalcemia, fracture, and nerve-compression syndromes. In this scenario, the bone destruction is mediated by the osteoclast. Tumor-produced parathyroid hormone-relate...

journal_title：Cancer

authors： Guise TA

更新日期：2000-06-15 00:00:00

abstract：BACKGROUND:Elderly people constitute a heterogeneous group and are at an increased risk for the development of cancer. It is not clear whether comorbid conditions and functional status influence clinical decisions and the pattern of referral in elderly cancer patients. The current study investigated functional status m...

journal_title：Cancer

authors： Repetto L,Venturino A,Vercelli M,Gianni W,Biancardi V,Casella C,Granetto C,Parodi S,Rosso R,Marigliano V

更新日期：1998-02-15 00:00:00

abstract：BACKGROUND:Childhood cancer is a highly curable disease when timely diagnosis and appropriate therapy are provided. A negative impact of the coronavirus disease 2019 (COVID-19) pandemic on access to care for children with cancer is likely but has not been evaluated. METHODS:A 34-item survey focusing on barriers to ped...

journal_title：Cancer

authors： Saab R,Obeid A,Gachi F,Boudiaf H,Sargsyan L,Al-Saad K,Javakhadze T,Mehrvar A,Abbas SS,Abed Al-Agele YS,Al-Haddad S,Al Ani MH,Al-Sweedan S,Al Kofide A,Jastaniah W,Khalifa N,Bechara E,Baassiri M,Noun P,El-Houdzi J,K

更新日期：2020-09-15 00:00:00

abstract：:Using a modified Feulgen hydrolysis procedure and integrating microdensitometry, the acid-labile nuclear DNA in exfoliated cervical epithelial cells was quantified in a range of histologically confirmed cervical intraepithelial neoplasia (CIN), invasive cancer, and normal controls. The mean relative optical densities ...

journal_title：Cancer

authors： Partington CK,Sincock AM,Steele SJ

更新日期：1991-06-15 00:00:00

abstract：:Methotrexate with citrovorum rescue (MTX-CF) was administered as primary treatment in 106 patients with gestational trophoblastic disease (GTD). Ninety-six patients (90.6%) achieved complete remission with MTX-CF and 77 of these patients (80.2%) required only one course of MTX-CF to attain remission. MTX-CF induced su...

journal_title：Cancer

authors： Berkowitz RS,Goldstein DP,Bernstein MR

更新日期：1982-11-15 00:00:00

abstract：BACKGROUND:The effect of p53 protein expression and MIB-1 proliferative activity on survival and chemotherapeutic response in patients with lymph node (LN)-positive transitional cell carcinoma (TCC) of the urinary bladder remains unclear. The objective of this study was to assess the ability of these markers to predict...

journal_title：Cancer

authors： Frank I,Cheville JC,Blute ML,Lohse CM,Karnes RJ,Weaver AL,Sebo TJ,Nehra A,Zincke H

更新日期：2004-10-15 00:00:00

abstract：BACKGROUND:Melanoma is the most lethal form of skin cancer, with an estimated 68,130 new cases and 8700 deaths in the United States in 2010. The increasing incidence and high death rate associated with metastatic disease support the need to focus on prevention. The authors used data from the Women's Health Initiative (...

journal_title：Cancer

authors： Jagtap D,Rosenberg CA,Martin LW,Pettinger M,Khandekar J,Lane D,Ockene I,Simon MS

更新日期：2012-10-15 00:00:00

abstract：:The authors describe two cases of Fournier's gangrene complicating aggressive therapy for hematologic malignancies. Fournier's gangrene is a fulminant necrotizing fasciitis of the scrotum and penis, often with an infectious etiology. Only one prior case has been reported in a patient receiving aggressive chemotherapy ...

journal_title：Cancer

authors： Berg A,Armitage JO,Burns CP

更新日期：1986-06-15 00:00:00

abstract：BACKGROUND:The purpose of the study was to determine the utility of quantitation of the extracellular domain (ECD) of the HER-2/neu receptor in the serum for predicting response to treatment in patients with primary breast cancer receiving neoadjuvant therapy. METHODS:HER-2/neu ECD was measured in sera obtained from 3...

journal_title：Cancer

authors： Mazouni C,Hall A,Broglio K,Fritsche H,Andre F,Esteva FJ,Hortobagyi GN,Buzdar AU,Pusztai L,Cristofanilli M

更新日期：2007-02-01 00:00:00