Angiogenesis in adenocarcinoma of the uterine cervix.

abstract：BACKGROUND:Gastrointestinal stromal tumors (GISTs) are a specific clinicopathologic entity characterized by activating mutations in the c-KIT gene. These mutations are associated with increased immunohistochemical staining for the c-KIT protein. Because many GISTs display a definitive response to the KIT inhibitor imat...

journal_title：Cancer

authors： Willmore-Payne C,Layfield LJ,Holden JA

更新日期：2005-06-25 00:00:00

abstract：BACKGROUND:The purpose of this project was to develop the M. D. Anderson Symptom Inventory (MDASI), a brief measure of the severity and impact of cancer-related symptoms. METHODS:A list of symptoms was generated from symptom inventories and by panels of clinicians. Twenty-six symptoms and 6 interference items were rat...

journal_title：Cancer

authors： Cleeland CS,Mendoza TR,Wang XS,Chou C,Harle MT,Morrissey M,Engstrom MC

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:Patients who present with squamous cell carcinoma metastatic to cervical lymph nodes and no clinically apparent primary site present a therapeutic dilemma. Positron emission tomography imaging with 2-[F-18]fluoro-2-deoxy-D-glucose (FDG-PET) has been shown to be useful for the examination of known primary tum...

journal_title：Cancer

authors： Greven KM,Keyes JW Jr,Williams DW 3rd,McGuirt WF,Joyce WT 3rd

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:Since the introduction of the TNM residual tumor (R) classification, the involvement of resection margins has been defined either as a microscopic (R1) or a macroscopic (R2) demonstration of tumor directly at the resection margin ("tumor transected"). METHODS:The recognition of the importance of the circumf...

journal_title：Cancer

authors： Wittekind C,Compton C,Quirke P,Nagtegaal I,Merkel S,Hermanek P,Sobin LH

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:This study was undertaken to determine whether the use of intermediate dose methotrexate in combination with vinblastine, doxorubicin, and cisplatin as first-line therapy increases the proportion of major responders and overall survival in patients with unresectable or metastatic transitional cell carcinoma ...

journal_title：Cancer

authors： Dodd PM,McCaffrey JA,Mazumdar M,Scher H,Vlamis V,Higgins G,Herr H,Bajorin DF

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:Endocrine therapy resistance is a major cause of distant recurrence (DR) in hormone receptor-positive breast cancer. This study evaluated differences in survival after DR in patients treated with different adjuvant endocrine therapy regimens in the Breast International Group (BIG) 1-98 trial. METHODS:BIG 1-...

journal_title：Cancer

authors： Leone JP,Cole BF,Regan MM,Thürlimann B,Coates AS,Rabaglio M,Giobbie-Hurder A,Gelber RD,Ejlertsen B,Harvey VJ,Neven P,Láng I,Bonnefoi H,Wardley A,Goldhirsch A,Di Leo A,Colleoni M,Vaz-Luis I,Lin NU

更新日期：2020-12-08 00:00:00

abstract：:Seventeen cases of intranasal epithelial tumors are reviewed. Thirteen were epithelial papillomas and four were squamous cell carcinomas associated with epithelial papillomas. In two cases followed over a 10 year period, transformation from an initial papilloma into a carcinoma was demonstrated. The histopathologic ca...

journal_title：Cancer

authors： Lasser A,Rothfeld PR,Shapiro RS

更新日期：1976-12-01 00:00:00

abstract：BACKGROUND:Tumor volume in radical prostatectomies can be determined by several different techniques and appears to predict clinical progression. Greatest tumor dimension and area are easily obtained measures that are both correlated with tumor volume. The authors sought to determine whether greatest tumor dimension an...

journal_title：Cancer

authors： Renshaw AA,Richie JP,Loughlin KR,Jiroutek M,Chung A,D'Amico AV

更新日期：1998-08-15 00:00:00

abstract：:An all inclusive, widely accepted system for correlation of indices of pathophysiology in endometrial cancer with a spectrum of therapeutic management has yet to be developed. Improved understanding of tumor growth should lead to more logical, individualized treatment especially in terms of irradiation. To support the...

journal_title：Cancer

authors： Lewis GC Jr,Mortel R,Slack NH

更新日期：1977-02-01 00:00:00

abstract：BACKGROUND:Tamoxifen has been used in the treatment of patients with metastatic malignant melanoma either as a single agent or, more commonly, in combination with other chemotherapeutic agents. The aim of the current study was to summarize the available clinical evidence on the role of the tamoxifen in different combin...

journal_title：Cancer

authors： Lens MB,Reiman T,Husain AF

更新日期：2003-10-01 00:00:00

abstract：:Three-hundred whole thyroid glands were collected at autopsy from patients who had no known clinical history of thyroid disease, and who varied from 13 to 82 years of age; 200 were male and 100 female. Thyroid glands were weighed, measured, and examined after previous formalin fixation. Histologic examination was done...

journal_title：Cancer

authors： Bisi H,Fernandes VS,de Camargo RY,Koch L,Abdo AH,de Brito T

更新日期：1989-11-01 00:00:00

abstract：:Plasma TSH and thyroxine levels were measured in 74 early breast cancer patients and 53 with advanced disease, 77 patients with cancer arising in other organs and 67 healthy women of similar age. The mean plasma TSH levels were higher in the breast cancer cases than the other two groups; the difference was statistical...

journal_title：Cancer

authors： Rose DP,Davis TE

更新日期：1978-02-01 00:00:00

abstract：:The authors add six patients with focal nodular hyperplasia of the liver to the increasing number reported. All had ingested hormones as contraceptives for periods of from one and one-half to seven years. In five patients, the initial manifestation was massive intraabdominal hemorrhage and hypovolemic shock. Five of t...

journal_title：Cancer

authors： Catalano PW,Early ME,Topolosky HW,Martin EW Jr,Carey LC

更新日期：1977-02-01 00:00:00

abstract：BACKGROUND:There is an increasing number of articles regarding the long term follow-up of Papanicolaou (Pap) smears with the diagnosis of atypical squamous cells of undetermined significance (ASCUS). Much controversy exists regarding the management of patients with this diagnosis. In a prior study in 1992, the authors ...

journal_title：Cancer

authors： Stastny JF,Remmers RE,London WB,Pedigo MA,Cahill LA,Ryan M,Frable WJ

更新日期：1997-12-25 00:00:00

abstract：BACKGROUND:To evaluate the immunologic activity of regional lymph nodes, the phenotype of lymphocytes and the functional expression of cell adhesion molecules (CAMs) on lymph node lymphocytes (LNL-: uninvolved, LNL+: involved) were investigated in patients with gastrointestinal carcinoma. METHODS:The lymphocyte subpop...

journal_title：Cancer

authors： Shinkal H,Kitayama J,Kimura W,Muto T,Shibata Y

更新日期：1996-10-15 00:00:00

abstract：:Six cases of desmoplastic melanoma were studied by light and electron microscopy. The tumors fulfilled one or more of the following criteria: (1) having the presence of atypical intraepidermal melanocytic proliferation bordering the primary lesions; (2) an antecedent history of melanoma at the site of recurrence; (3) ...

journal_title：Cancer

authors： DiMaio SM,Mackay B,Smith JL Jr,Dickersin GR

更新日期：1982-12-01 00:00:00

abstract：:This protocol study (SWOG-7431) combining adriamycin and methyl CCNU (MAD) for metastatic sarcomas was initially used on patients who were refractory to cytoxan, vincristine, and/or actinomycin-D. After the initial good results, the study was expanded to include any untreated patients with metastatic sarcoma. The init...

journal_title：Cancer

authors： Rivkin SE,Gottlieb JA,Thigpen T,El Mawla NG,Saiki J,Dixon DO

更新日期：1980-08-01 00:00:00

abstract：:Increased in vitro tetraploidy occurred in skin cultures derived from all affected patients and some family members at risk studied in families with heritable colon cancer syndromes (15 of 16 Gardner syndrome families, three Oldfield syndrome families, and four families with heritable colon cancer syndrome without pol...

journal_title：Cancer

authors： Danes BS

更新日期：1981-10-01 00:00:00

abstract：BACKGROUND:The objective of the current study was to correlate pretreatment computed tomography and magnetic resonance imaging studies with outcomes for patients with squamous or basal cell carcinoma of the skin and clinical perineural invasion. METHODS:Between 1986 and 2002, 45 patients were treated with radiotherapy...

journal_title：Cancer

authors： Galloway TJ,Morris CG,Mancuso AA,Amdur RJ,Mendenhall WM

更新日期：2005-03-15 00:00:00

abstract：BACKGROUND:Attrition is common among supportive care/palliative oncology clinical trials. However, to the authors' knowledge, few studies to date have documented the reasons and predictors for dropout. In the current study, the authors' objective was to determine the rate, reasons, and factors associated with attrition...

journal_title：Cancer

authors： Hui D,Glitza I,Chisholm G,Yennu S,Bruera E

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Conditional survival is clinically useful, particularly for patients with malignant disease who have a poor prognosis. However, there are no published data on the conditional median survival of patients with advanced carcinoma on a population basis. METHODS:Data on 217,573 patients with breast, colorectal, ...

journal_title：Cancer

authors： Kato I,Severson RK,Schwartz AG

更新日期：2001-10-15 00:00:00

abstract：BACKGROUND:Hypermethylation of CpG islands has been associated with silencing of various tumor suppressor genes, and the retinoid acid receptor beta (RARbeta), cellular retinol-binding protein 1 (CRBP1), and tazarotene-induced gene 1 (TIG1) genes have been associated with retinoic acid signaling. To the authors' knowle...

journal_title：Cancer

authors： Shutoh M,Oue N,Aung PP,Noguchi T,Kuraoka K,Nakayama H,Kawahara K,Yasui W

更新日期：2005-10-15 00:00:00

abstract：BACKGROUND:This study explores whether externalizing religious and spiritual beliefs is associated with advanced-stage colon cancer at initial oncology presentation and whether this association is stronger for blacks than for whites. METHODS:Patients who had newly diagnosed, invasive colon cancer were recruited at 9 s...

journal_title：Cancer

authors： Polite BN,Cipriano-Steffens TM,Hlubocky FJ,Jean-Pierre P,Cheng Y,Brewer KC,Rauscher GH,Fitchett GA

更新日期：2018-06-15 00:00:00

abstract：BACKGROUND:Patients with aggressive non-Hodgkin lymphoma (NHL) require intensive and extensive therapy, which seems impracticable in elderly patients due to hematologic and extrahematologic toxicity. Consequent dose reduction and therapy attenuation can reduce treatment-related toxicity but also decreases therapeutic e...

journal_title：Cancer

authors： Rigacci L,Carpaneto A,Alterini R,Carrai V,Bernardi F,Bellesi G,Longo G,Bosi A,Rossi Ferrini P

更新日期：2003-01-01 00:00:00

abstract：:The authors evaluated specific gamma-GTP isoenzyme (specific gamma-GTP) found in sera of patients with hepatocellular carcinoma (HCC). In addition to band II and II' which had been reported in our previous publication, band I' also had a high specificity for HCC. One or more of these bands were detectable in 109 (55%)...

journal_title：Cancer

authors： Sawabu N,Nakagen M,Ozaki K,Wakabayashi T,Toya D,Hattori N,Ishii M

更新日期：1983-01-15 00:00:00

abstract：:A series of 27 typical Krukenberg tumors of the ovary were analyzed. By definition, all examples were characterized by the presence of mucinous signet-ring carcinoma cells within a cellular, nonneoplastic ovarian stroma. The patients' ages ranged from 20-70 years; almost one-half were 40 years of age or younger. A pri...

journal_title：Cancer

authors： Holtz F,Hart WR

更新日期：1982-12-01 00:00:00

abstract：BACKGROUND:Exercise is a modifiable lifestyle risk factor associated with prostate cancer risk reduction. However, whether this association is different as a function of race is unclear. In the current study, the authors attempted to characterize the link between exercise and prostate cancer (CaP) in white and black Am...

journal_title：Cancer

authors： Singh AA,Jones LW,Antonelli JA,Gerber L,Calloway EE,Shuler KH,Freedland SJ,Grant DJ,Hoyo C,Bañez LL

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Central neurocytomas are composed of mature neuronal elements, frequently arranged in rosettes similar to those present in pineocytomas. This suggests the possibility of similar patterns of differentiation, including photoreceptor differentiation. The authors analyzed the immunoreactivity of central neurocyt...

journal_title：Cancer

authors： Mena H,Morrison AL,Jones RV,Gyure KA

更新日期：2001-01-01 00:00:00

abstract：:Thirteen patients with a variety of advanced gynecologic malignancies were administered BCG via the dorsal lymphatics of the lower extremity in addition to standard accepted forms of therapy. Prolonged febrile courses, lymphangitis and suppurative adenitis were observed along the lymphatic pathway of the injected lowe...

journal_title：Cancer

authors： Mangan C,Jeglum KA,Sedlacek TV,Giuntoli RL,Wheeler JE,Rubin E,Mikuta JJ

更新日期：1977-12-01 00:00:00

abstract：BACKGROUND:Screening for and the aggressive treatment of prostate carcinoma are controversial, but they are nevertheless being practiced in the U.S. Current clinical studies of the effectiveness of screening will take years to complete. Meanwhile, screening for prostate carcinoma is already having an effect on society....

journal_title：Cancer

authors： Brawley OW

更新日期：1997-11-01 00:00:00