c-KIT mutation analysis for diagnosis of gastrointestinal stromal tumors in fine needle aspiration specimens.

abstract：BACKGROUND:Smoldering multiple myeloma (SMM) presents a high risk of progression to symptomatic MM (sy-MM). Herein, we analyzed some predictors of development of sy-MM. In 144 patients with SMM, we also compared the risk of progression predicted by bone marrow plasma cell (BMPC) involvement on the bone marrow biopsy (B...

journal_title：Cancer

authors： Rago A,Grammatico S,Za T,Levi A,Mecarocci S,Siniscalchi A,De Rosa L,Felici S,Bongarzoni V,Piccioni AL,La Verde G,Pisani F,Franceschini L,Paviglianiti AL,Caravita T,Petrucci MT,De Stefano V,Cimino G,Multiple Myeloma GI

更新日期：2012-11-15 00:00:00

abstract：:Compliance in oncology clinic attendance was prospectively evaluated over a 12-month period at Harlem Hospital Center, an inner city municipal facility serving a predominantly black population. One hundred patients were followed (97 blacks, 2 Hispanics, 1 white) with an average age of 60 years. There were 41 men and 5...

journal_title：Cancer

authors： Garrett TJ,Ashford A,Savage DG

更新日期：1986-08-01 00:00:00

abstract：BACKGROUND:Adult "translocation" renal cell carcinoma (RCC), bearing transcription factor E3 (TFE3) gene fusions at Xp11.2, is a recently recognized, unique entity for which prognosis and therapy remain poorly understood. In the current study, the authors investigated the effect of vascular endothelial growth factor (V...

journal_title：Cancer

authors： Choueiri TK,Lim ZD,Hirsch MS,Tamboli P,Jonasch E,McDermott DF,Dal Cin P,Corn P,Vaishampayan U,Heng DY,Tannir NM

更新日期：2010-11-15 00:00:00

abstract：BACKGROUND:Prostate adenocarcinoma is predominantly a disease of older men. Males younger than 50 years account for 1% of all patients with prostate cancer. The authors retrospectively examined cases of prostate adenocarcinoma in patients younger than 50 years of age to determine the natural history and prognosis of th...

journal_title：Cancer

authors： Aprikian AG,Zhang ZF,Fair WR

更新日期：1994-09-15 00:00:00

abstract：BACKGROUND:To study the correlation of environmental exposure to potentially mutagenic agents and the clinicopathologic picture in acute myeloid leukemia (AML), clinical features, morphologic characteristics, immunophenotype, and cytogenetics were studied in 59 patients with newly diagnosed AML. METHODS:Based on inter...

journal_title：Cancer

authors： Fagioli F,Cuneo A,Piva N,Carli MG,Previati R,Balboni M,Tomasi P,Cariani D,Scapoli G,Castoldi G

更新日期：1992-07-01 00:00:00

abstract：:A family with histopathologically proven intraocular malignant melanoma involving two generations is reported. A member of third generation was likely involved by history. Intraocular malignant melanoma, its familial occurrence, its occurrence with multiple malignancies, and its relationship to multiple malignancies o...

journal_title：Cancer

authors： Green GJ,Hong WK,Everett JR,Bhutani R,Amick RM

更新日期：1978-06-01 00:00:00

abstract：:The prognostic value of nuclear DNA content was studied retrospectively using flow cytometry in 203 cases of resected hepatocellular carcinoma. The occurrence of DNA aneuploidy, which was detected in 50% of patients, correlated significantly with tumor size and the presence of vascular invasion or intrahepatic metasta...

journal_title：Cancer

authors： Fujimoto J,Okamoto E,Yamanaka N,Toyosaka A,Mitsunobu M

更新日期：1991-02-15 00:00:00

abstract：:A 78-year-old Japanese man with chronic liver disease developed hypervascular liver tumors accompanied by marked elevation of alphafetoprotein value (the highest level; 26200 ng/ml) and pathologic fracture of the femur. After an operation for the fracture followed by gastrointestinal bleeding and repeated transfusions...

journal_title：Cancer

authors： Sato Y,Fujiwara K,Nakagawa S,Kanishima S,Ohta Y,Oka Y,Hayashi S,Oka H

更新日期：1985-08-01 00:00:00

abstract：:The objective of this study was to evaluate the sensitivity of two methods for determining bone marrow involvement with non-Hodgkin's lymphoma. These methods were histologic review of bone marrow aspirates, and clot sections versus in vitro growth of lymphoma colonies on soft agar. Forty-two bone marrow aspirates were...

journal_title：Cancer

authors： Smith SD,Kisker S,Bush L,Trueworthy RC

更新日期：1984-04-15 00:00:00

abstract：:Univariate and multivariate regression methods were used to analyze 17 potential clinical prognostic factors among 138 patients with advanced breast cancer who received Adriamycin-cyclophosphamide combination chemotherapy between 1973 and 1977 at the University of Arizona. Follow-up of patients was through September 1...

journal_title：Cancer

authors： Nash CH 3rd,Jones SE,Moon TE,Davis SL,Salmon SE

更新日期：1980-12-01 00:00:00

abstract：BACKGROUND:To evaluate the immunologic activity of regional lymph nodes, the phenotype of lymphocytes and the functional expression of cell adhesion molecules (CAMs) on lymph node lymphocytes (LNL-: uninvolved, LNL+: involved) were investigated in patients with gastrointestinal carcinoma. METHODS:The lymphocyte subpop...

journal_title：Cancer

authors： Shinkal H,Kitayama J,Kimura W,Muto T,Shibata Y

更新日期：1996-10-15 00:00:00

abstract：:One hundred fifteen patients underwent surgical treatment of renal cell carcinoma. Survival time was analyzed by statistical regression methods in order to determine the joint significance of stage, using both the Robson and TNM classifications, histologic grade, cell type, and demographic features of the patient samp...

journal_title：Cancer

authors： Selli C,Hinshaw WM,Woodard BH,Paulson DF

更新日期：1983-09-01 00:00:00

abstract：BACKGROUND:Recent clinical studies have demonstrated that tumor angiogenesis is a potent prognostic indicator for breast cancer patients. The quantitation of endothelial growth factors is thought to be useful to assess angiogenic phenotype in the tumor. Among the many new endothelial growth factors, vascular endothelia...

journal_title：Cancer

authors： Toi M,Kondo S,Suzuki H,Yamamoto Y,Inada K,Imazawa T,Taniguchi T,Tominaga T

更新日期：1996-03-15 00:00:00

abstract：BACKGROUND:It has been shown that adoptive immunotherapy with Epstein-Barr virus (EBV)-specific cytotoxic T-lymphocytes (CTL) is effective for the treatment of EBV-induced lymphoproliferative disease in stem cell transplantation recipients and organ transplantation recipients. The role of EBV CTL in other tumors for wh...

journal_title：Cancer

authors： Lucas KG,Salzman D,Garcia A,Sun Q

更新日期：2004-05-01 00:00:00

abstract：:Five patients with hepatocellular carcinoma in the caudate lobe were evaluated. Computed tomography (CT) scan and/or angiography clearly demonstrated multiple intrahepatic metastases in four (80%), and tumor thrombi in the portal vein in two (40%), and in the inferior vena cava in one. Even though there was no recogni...

journal_title：Cancer

authors： Takayasu K,Muramatsu Y,Shima Y,Goto H,Moriyama N,Yamada T,Makuuchi M,Kaneko A,Itabashi M,Shimamura Y

更新日期：1986-10-01 00:00:00

abstract：:Acute nonlymphocytic leukemia (ANLL) developed in four patients 66 to 157 months following the diagnosis of nodular poorly differentiated lymphocytic lymphoma (PDL-N). The ANLL was signalled by increasing anemia and thrombocytopenia. A characteristic cytologic pattern of the leukemia was found. In each patient, a panm...

journal_title：Cancer

authors： Collins AJ,Bloomfield CD,Peterson BA,McKenna RW

更新日期：1977-10-01 00:00:00

abstract：BACKGROUND:Gene expression profiling (GEP) has been rapidly adopted for early breast cancer and can aid in chemotherapy decision making. Study results regarding racial disparities in testing are conflicting, and may reflect different care settings. To the authors' knowledge, data regarding the influence of provider fac...

journal_title：Cancer

authors： Reeder-Hayes KE,Wheeler SB,Baggett CD,Zhou X,Meng K,Roberts MC,Carey LA,Meyer AM

更新日期：2018-04-15 00:00:00

abstract：BACKGROUND:The first step of colorectal carcinoma spread depends on the ability of the tumor cells to degrade and invade the extracellular matrix (ECM). The objectives of the current study were to evaluate the serum pattern of laminin, C-terminal peptide of Type I (PIP), and N-terminal peptide of Type III (PIIIP) proco...

journal_title：Cancer

authors： Plebani M,Basso D,Roveroni G,De Paoli M,Galeotti F,Corsini A

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:The Hanford Tribal Service Program offers technical assistance and health education to American Indian tribes in an area reported to be affected by radiation from the Hanford Nuclear Reservation, which was developed and operated by the United States federal government. This article describes strategies used ...

journal_title：Cancer

authors： Jensen RA

更新日期：1996-10-01 00:00:00

abstract：:True adenomas of the breast are cellular epithelial lesions, which may be confused with carcinoma and are difficult to classify. We have reviewed 28 adenomas of the breast and have developed specific diagnostic criteria, as well as a classification of breast adenomas based on histologic features. Electron microscopic ...

journal_title：Cancer

authors： Hertel BF,Zaloudek C,Kempson RL

更新日期：1976-06-01 00:00:00

abstract：:Breast cancer specimens from 600 women were assayed for estrogen receptors (ER) using an immunocytochemical assay (ICA) employing the monoclonal antiestrophilin antibody H222 Sp gamma. Results showed significant correlation with biochemical ER determinations as well as with tumor grade and menopausal status. In 449 ca...

journal_title：Cancer

authors： Pertschuk LP,Kim DS,Nayer K,Feldman JG,Eisenberg KB,Carter AC,Rong ZT,Thelmo WL,Fleisher J,Greene GL

更新日期：1990-10-15 00:00:00

abstract：BACKGROUND:Women treated with tamoxifen for breast cancer are at increased risk of endometrial cancer. This study examines the experience at Roswell Park Cancer Institute (RPCI) with women diagnosed with both endometrial carcinoma (EC) and breast carcinoma (BC) to determine the risk and stage of endometrial carcinoma a...

journal_title：Cancer

authors： Cuenca RE,Giachino J,Arredondo MA,Hempling R,Edge SB

更新日期：1996-05-15 00:00:00

abstract：:An in vivo model is described for assessing the antitumor activity of chemotherapeutic agents. Tumors derived from human colon carcinoma cell lines injected into antithymocyte serum (ATS) immunosuppressed mice were used. In this system, both antitumor effects and host toxicity can be quantitated, permitting calculatio...

journal_title：Cancer

authors： Tibbetts LM,Chu MY,Hager JC,Dexter DL,Calabresi P

更新日期：1977-11-01 00:00:00

abstract：:The medical records of 243 patients admitted over a five-year period with a diagnosis of carcinoma of the cervix were reviewed to determine (1) the frequency of pulmonary metastasis, (2) the relationship between the stage of the primary lesion and the incidence of pulmonary metastasis, and (3) the relationship between...

journal_title：Cancer

authors： Tellis CJ,Beechler CR

更新日期：1982-04-15 00:00:00

abstract：:Over an 18-year period a distinctive large cell lymphoreticular neoplasm (Richter's transformation) developed in 9 patients with chronic lymphocytic leukemia. Clinical findings at the onset of Richter's transformation were remarkably uniform and consisted of the abrupt onset of fever, marked asymmetric lymphadenopathy...

journal_title：Cancer

authors： Foucar K,Rydell RE

更新日期：1980-07-01 00:00:00

abstract：:High tissue concentrations of human chorionic gonadotropin (hCG) and alpha-fetoprotein (AFP) were revealed by radioimmunoassay in a hepatic tumor which was surgically removed from a two-year, eight-month-old boy manifesting sexual precocity. Histologically the tumor showed an embryonal type hepatoblastoma admixed with...

journal_title：Cancer

authors： Morinaga S,Yamaguchi M,Watanabe I,Kasai M,Ojima M,Sasano N

更新日期：1983-05-01 00:00:00

abstract：BACKGROUND:Filanesib (ARRY-520) is a highly selective inhibitor of kinesin spindle protein, which has demonstrated preclinical antimyeloma activity. METHODS:This open-label Phase 1/2 study determined the maximum tolerated dose of Filanesib administered on Days 1 and 2 of 14-Day Cycles in patients with multiple myeloma...

journal_title：Cancer

authors： Shah JJ,Kaufman JL,Zonder JA,Cohen AD,Bensinger WI,Hilder BW,Rush SA,Walker DH,Tunquist BJ,Litwiler KS,Ptaszynski M,Orlowski RZ,Lonial S

更新日期：2017-12-01 00:00:00

abstract：:In malignant melanoma, using Sephadex G-200 chromatography and polyacrylamide gel electrophoresis (PAGE), it has been possible to separate two types of skin reactive antigens. The first, found in Sephadex fraction II and PAGE region a appears specific for melanoma. Allogeneic extracts have produced positive reactions ...

journal_title：Cancer

authors： Hollinshead AC

更新日期：1975-10-01 00:00:00

abstract：BACKGROUND:Radiation recall refers to a tissue reaction produced by a chemotherapeutic agent in a previously irradiated field that would not occur in a nonirradiated field. A number of agents have been reported to cause radiation recall. Recently, there have been case reports of recall dermatitis from paclitaxel treatm...

journal_title：Cancer

authors： Schweitzer VG,Juillard GJ,Bajada CL,Parker RG

更新日期：1995-09-15 00:00:00

abstract：:Cases of systemic lupus erythematosus, systemic sclerosis, periarteritis nodosa, and dermato- and polymyositis autopsied in Japan during a recent, 7-year period (1972-1978) were studied to assess the incidence of cancer as a complication. In comparison with the other three groups, cases of dermato- and polymyositis (D...

journal_title：Cancer

authors： Okayasu I,Mizutani H,Kurihara H,Yanagisawa F

更新日期：1984-11-01 00:00:00