Prediction of outcome in metastatic breast cancer treated with adriamycin combination chemotherapy.

abstract：:The clinical course of 29 patients with idiopathic refractory sideroblastic anemia studied by us was reviewed. Four patients developed acute leukemia. We were able to find 27 out of 268 cases of idiopathic refractory sideroblastic anemia reported in the literature which terminated in acute leukemia. Nine of these were...

journal_title：Cancer

authors： Cheng DS,Kushner JP,Wintrobe MM

更新日期：1979-08-01 00:00:00

abstract：BACKGROUND:Reports on lymphoid malignancy and its treatment in children infected with human immunodeficiency virus (HIV) are limited. METHODS:Antibodies to Epstein-Barr virus (EBV) were detected by indirect immunofluorescence. DNA was extracted from peripheral blood lymphocytes or biopsy specimens. Polymerase chain re...

journal_title：Cancer

authors： Nadal D,Caduff R,Frey E,Hassam S,Zimmermann DR,Seigneurin JM,Plüss HJ,Seger RA

更新日期：1994-01-01 00:00:00

abstract：:The authors retrospectively searched for human papillomavirus (HPV) types 16 and 18 in 60 cases of carcinoma arising from the nasal cavities (NC) and paranasal sinuses (PS) by using the polymerase chain reaction (PCR) on DNA extracted from formalin-fixed, paraffin-embedded tissues. In cases of SCC (n = 49), the author...

journal_title：Cancer

authors： Furuta Y,Takasu T,Asai T,Shinohara T,Sawa H,Nagashima K,Inuyama Y

更新日期：1992-01-15 00:00:00

abstract：:In 186 women with breast cancer, there was a progressive increase in the proportion of axillary nodal involvement as the number of pregnancies increased from zero to two or more (P = 0.026). Logistic regression analysis demonstrated that this effect was independent of the known relationship of age and tumor size to no...

journal_title：Cancer

authors： Lehrer S,Levine E,Savoretti P,Cropley J,Botstein C,Song HK,Mandell L,Shank B

更新日期：1992-02-15 00:00:00

abstract：BACKGROUND:Patient navigation may reduce cancer disparities associated with socioeconomic status (SES) and household factors. This study examined whether these factors were associated with delays in diagnostic resolution among patients with cancer screening abnormalities and whether patient navigation ameliorated these...

journal_title：Cancer

authors： Rodday AM,Parsons SK,Snyder F,Simon MA,Llanos AA,Warren-Mears V,Dudley D,Lee JH,Patierno SR,Markossian TW,Sanders M,Whitley EM,Freund KM

更新日期：2015-11-15 00:00:00

abstract：BACKGROUND:Currently, no standard therapy exists for patients with relapsed and/or refractory non-Hodgkin lymphoma (NHL) who are ineligible for transplantation or who have failed after bone marrow transplantation. The authors of this report investigated the safety and efficacy of clofarabine (CLO) in these patients. M...

journal_title：Cancer

authors： Nabhan C,Davis N,Bitran JD,Galvez A,Fried W,Tolzien K,Foss S,Dewey WM,Venugopal P

更新日期：2011-04-01 00:00:00

abstract：:There is a growing body of basic science and epidemiologic evidence to support a research thrust to determine whether several natural or synthetic agents, given alone or together, can lower cancer incidence. Candidate agents include analogs of vitamin A and the vitamin A precursor, beta-carotene, vitamins C and E, and...

journal_title：Cancer

authors： Malone WF,Kelloff GJ,Pierson H,Greenwald P

更新日期：1987-08-01 00:00:00

abstract：:Four cell lines were derived from childhood malignancies: rhabdomyosarcoma, sarcoma, lymphosarcoma and an American Burkitt's lymphoma. Cells of the four lines formed tumors in immunosuppressed newborn hamsters. The tumors had a microscopic appearance like that of the tumors from which the cell lines were derived. No ...

journal_title：Cancer

authors： McAllister RM,Nelson-Rees WA,Peer M,Laug WE,Isaacs H Jr,Gilden RV,Rongey RW,Gardner MB

更新日期：1975-11-01 00:00:00

abstract：:Nine years after biopsy and radiation therapy for an extramedullary plasmacytoma of the nasal cavity, a 64-year-old man developed locally recurrent tumor. Repeat biopsy revealed tumor identical in hematoxylin and eosin stain (H & E) appearance to that found originally, leading to the diagnosis of recurrent extramedull...

journal_title：Cancer

authors： Abrams RA,Wilson JF,Komorowski RA,Collins D,Toohill RJ

更新日期：1987-07-01 00:00:00

abstract：BACKGROUND:Cyclin-dependent kinases (CDK) and cyclins constitute the subunits of the maturation-promoting factor that controls the process of cell division. High levels of these proteins have been reported in human malignancies of the stomach, colon, breast, and lung, and have been implicated in aberrant cell division ...

journal_title：Cancer

authors： Kallakury BV,Sheehan CE,Ambros RA,Fisher HA,Kaufman RP Jr,Ross JS

更新日期：1997-08-15 00:00:00

abstract：BACKGROUND:To enhance the efficacy of chemotherapy for medullary thyroid carcinoma (MTC), we evaluated the effect of combining radioimmunotherapy (RAIT) with 90Y-anticarcinoembryonic antigen (CEA) monoclonal antibody MN-14 and chemotherapy in nude mice bearing human MTC xenografts. A preliminary study evaluated doxorub...

journal_title：Cancer

authors： Stein R,Chen S,Reed L,Richel H,Goldenberg DM

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:For patients who have chondrosarcoma with unresectable disease, because of tumor location, tumor size, or extensive metastatic disease, treatment options are very limited because of their relative resistance to radiotherapy and chemotherapy. The overall survival of this patient population is poor; however, s...

journal_title：Cancer

authors： van Maldegem AM,Gelderblom H,Palmerini E,Dijkstra SD,Gambarotti M,Ruggieri P,Nout RA,van de Sande MA,Ferrari C,Ferrari S,Bovée JV,Picci P

更新日期：2014-10-15 00:00:00

abstract：BACKGROUND:The authors evaluated the role of 5-aminolevulinic acid (5-ALA)-induced fluorescence endoscopy (AFE) in the detection of flat urothelial lesions in light of the suggestions made for flat neoplastic lesions within the 1999 World Health Organization (WHO) classification of urinary bladder tumors. METHODS:From...

journal_title：Cancer

authors： Zaak D,Hungerhuber E,Schneede P,Stepp H,Frimberger D,Corvin S,Schmeller N,Kriegmair M,Hofstetter A,Knuechel R

更新日期：2002-09-15 00:00:00

abstract：BACKGROUND:Interferon-alpha (IFN-alpha) has shown significant activity in the treatment of BCR-ABL-negative myeloproliferative disorders (MPDs), particularly essential thrombocythemia (ET) and polycythemia vera (PV). PEG-IFN-alpha-2b is a pegylated IFN-alpha-2b with a significant advantage over nonpegylated form in tha...

journal_title：Cancer

authors： Jabbour E,Kantarjian H,Cortes J,Thomas D,Garcia-Manero G,Ferrajoli A,Faderl S,Richie MA,Beran M,Giles F,Verstovsek S

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:The mode of tumor growth of intrahepatic cholangiocarcinoma (CC) varies considerably from patient to patient. This study describes the clinicopathologic variety of the extraductal mass-forming type of CC. METHODS:Patients with CC characterized by an extraductal mass (n = 26) who underwent hepatectomy from 1...

journal_title：Cancer

authors： Yamanaka N,Okamoto E,Ando T,Oriyama T,Fujimoto J,Furukawa K,Tanaka T,Tanaka W,Nishigami T

更新日期：1995-12-15 00:00:00

abstract：BACKGROUND:Inferior vena cava obstruction (IVCO) is a poorly characterized complication of metastatic germ cell tumor (GCT). The authors identified 31 cases to describe the clinical features, radiologic findings, complications, and treatment of this clinical entity. METHODS:Patients with GCT and IVCO were identified f...

journal_title：Cancer

authors： Hassan B,Tung K,Weeks R,Mead GM

更新日期：1999-02-15 00:00:00

abstract：:Only three previous reports on the ultrastructural appearance of tibial adamantinoma have been found among some 120 cases of this tumor reported in the literature. The tumor in our case is less differentiated than the cases previously reported. We believe it is of epithelial character and the possibilities of its hist...

journal_title：Cancer

authors： Yoneyama T,Winter WG,Milsow L

更新日期：1977-09-01 00:00:00

abstract：:The nitroblue tetrazolium test (NBT) was evaluated in 111 patients with cancer. Patients were placed into control and "presumed infected" groups. The mean NBT score for the control group, 6.3, was significantly greater than the mean for a group of normal volunteers, 3.1, but the mean score for the "presumed infected" ...

journal_title：Cancer

authors： Lehane DE,Watson S,Lane M

更新日期：1975-05-01 00:00:00

abstract：BACKGROUND:Tyrosine kinases, such as c-KIT, c-ABL, and platelet-derived growth factor-beta (PDGFR-beta), are important regulators of cell growth. Highly potent and selective inhibitors of tyrosine kinases are being investigated as alternatives to standard chemotherapy. One such inhibitor, imatinib mesylate, is being us...

journal_title：Cancer

authors： Schmandt RE,Broaddus R,Lu KH,Shvartsman H,Thornton A,Malpica A,Sun C,Bodurka DC,Gershenson DM

更新日期：2003-08-15 00:00:00

abstract：:The unique case of a 60-year-old patient with a non-Hodgkin's B-cell lymphoma of the lymphoplasmacytic type and three associated monoclonal proteins, is described. The patient also exhibited various autoimmune phenomena that were consistent with the diagnoses of Sjögren's syndrome and autoimmune thyroiditis. The evolu...

journal_title：Cancer

authors： Berg AR,Weisenburger DD,Linder J,Armitage JO

更新日期：1986-05-01 00:00:00

abstract：:A case of congenital acute lymphoblastic leukemia (ALL) displayed an X;6 translocation. This is the third reported case of ALL with an X;6 translocation. In addition, two of the three ALL cases occurred during infancy, at ages 2 months and newborn, and both translocations involved the band q15-16 region of chromosome ...

journal_title：Cancer

authors： Carney LA,Kinney JS,Higgins RR,Freeman AI,Hecht BK,Woods GM

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:Late menarche, early menopause, high parity, and early first birth decrease the risk of development of breast cancer. The influence of these factors on the survival of breast cancer patients has not been explained. METHODS:A group of 1885 patients with operable breast cancer was studied retrospectively. A u...

journal_title：Cancer

authors： Korzeniowski S,Dyba T

更新日期：1994-09-01 00:00:00

abstract：:Plasma TSH and thyroxine levels were measured in 74 early breast cancer patients and 53 with advanced disease, 77 patients with cancer arising in other organs and 67 healthy women of similar age. The mean plasma TSH levels were higher in the breast cancer cases than the other two groups; the difference was statistical...

journal_title：Cancer

authors： Rose DP,Davis TE

更新日期：1978-02-01 00:00:00

abstract：BACKGROUND:Bisphosphonates currently are the most important class of antiresorptive agents used in the treatment of metabolic bone diseases, including tumor-associated osteolysis and hypercalcemia, Paget's disease, and osteoporosis. These compounds have high affinity for calcium and therefore target to bone mineral, wh...

journal_title：Cancer

authors： Rogers MJ,Gordon S,Benford HL,Coxon FP,Luckman SP,Monkkonen J,Frith JC

更新日期：2000-06-15 00:00:00

abstract：:A clinicopathologic study of 48 cases of pleomorphic lipoma from the files of the Armed Forces Institute of Pathology reveals that this tumor occurs principally in males (83%) in the fifth to seventh decades (mean 57 years) and shows a predilection for the posterior neck, shoulder, and back. Typically, the lesion appe...

journal_title：Cancer

authors： Shmookler BM,Enzinger FM

更新日期：1981-01-01 00:00:00

abstract：:Interest in the elderly population, persons 65 years of age or older, as a target group for cancer control has not been great. Age recommendations rarely are made for prevention and early detection of cancer for elderly persons. However, cancer incidence and mortality rates are known to rise rapidly with increasing ag...

journal_title：Cancer

authors： Yancik R,Kessler L,Yates JW

更新日期：1988-10-15 00:00:00

abstract：BACKGROUND:Despite Helicobacter pylori (HP) eradication, individuals can still develop gastric cancer (GC). Prior studies have demonstrated that nonaspirin nonsteroidal anti-inflammatory drugs (NA-NSAIDs) reduce the risk of GC, but this may be caused by immortal time bias and failure to adjust for HP status. The object...

journal_title：Cancer

authors： Li B,Cheung KS,Wong IY,Leung WK,Law S

更新日期：2021-01-20 00:00:00

abstract：BACKGROUND:The Centers for Medicare and Medicaid Services (CMS) has released quality measures regarding potentially avoidable hospitalizations visits in the 30 days after receipt of outpatient chemotherapy. This study evaluated the proportions of patients treated by Medicare-reimbursed clinicians and Veterans Health Ad...

journal_title：Cancer

authors： Gidwani-Marszowski R,Faricy-Anderson K,Asch SM,Illarmo S,Ananth L,Patel MI

更新日期：2020-07-15 00:00:00

abstract：BACKGROUND:Radiofrequency thermal ablation (RFA) is a new minimally invasive treatment for localized cancer. Minimally invasive surgical options require less resources, time, recovery, and cost, and often offer reduced morbidity and mortality, compared with more invasive methods. To be useful, image-guided, minimally i...

journal_title：Cancer

authors： Wood BJ,Ramkaransingh JR,Fojo T,Walther MM,Libutti SK

更新日期：2002-01-15 00:00:00

abstract：:High-dose multiagent chemotherapy followed by autologous marrow rescue was used in the treatment of 13 patients with Stage III or IV childhood tumors. Encouraging results are being obtained in abdominal lymphoma (1/3 complete remissions (CR); rhabdomyosarcoma (2/4 CR); and retinoblastoma (1/2 CR). In neuroblastoma, th...

journal_title：Cancer

authors： Ekert H,Ellis WM,Waters KD,Tauro GP

更新日期：1982-02-01 00:00:00