Chemotherapy of cell-line-derived human colon carcinomas in mice immunosuppressed with antithymocyte serum.

abstract：:The possible influence of histologic grade, necrosis and size of invasive breast cancers on the five year survival rate of women treated in NSABP clinical trials with regimens of L-PAM (P) and L-PAM + 5-FU (PF) and for four years in those receiving L-PAM + 5-FU + methotrexate (PMF) was investigated. Generally, all reg...

journal_title：Cancer

authors： Fisher ER,Redmond C,Fisher B

更新日期：1983-01-15 00:00:00

abstract：BACKGROUND:Hypercalcemia of malignancy (HM) is one of the commonest metabolic complications associated with cancer. Plasma parathyroid hormone-related peptide (PTH-rp) is known to cause hypercalcemia in the vast majority of patients with HM. METHODS:Fifty-two patients with HM were treated with a single infusion of 60 ...

journal_title：Cancer

authors： Wimalawansa SJ

更新日期：1994-04-15 00:00:00

abstract：:A 24-year-old woman was found to have a diffuse large cell lymphoma arising within thyroid tissue within a mature cystic teratoma of the ovary. To the authors' knowledge, this is the first reported case of malignant lymphoma arising within a teratoma of the ovary. ...

journal_title：Cancer

authors： Seifer DB,Weiss LM,Kempson RL

更新日期：1986-12-01 00:00:00

abstract：BACKGROUND:Lysosomal proteases are implicated in cancer progression and metastasis. In the current study, using subtraction cloning for genes that are differentially expressed in metastasis, the authors isolated a clone encoding ceroid lipofuscinosis, neuronal 2 (CLN2), which is a lysosomal serine protease defective in...

journal_title：Cancer

authors： Tsukamoto T,Iida J,Dobashi Y,Furukawa T,Konishi F

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:There are three distinct types of doxorubicin-induced cardiotoxicity (acute, chronic, and late-onset). Although previous studies with animal models suggest that angiotensin II plays a key role in the process of the doxorubicin-induced cardiotoxicity, there has been no such observation in humans. This randomi...

journal_title：Cancer

authors： Nakamae H,Tsumura K,Terada Y,Nakane T,Nakamae M,Ohta K,Yamane T,Hino M

更新日期：2005-12-01 00:00:00

abstract：:A brother and sister with Fanconi's anemia, having typical skeletal deformity and characteristic chromosomal breaks in their lymphocytes and who followed the typical clinical course, with progressive bone marrow insufficiency beginning late in the first decade, are described. The natural history of the disease before ...

journal_title：Cancer

authors： Jacobs P,Karabus C

更新日期：1984-11-01 00:00:00

abstract：:Two patients fulfilled the clinical and hematologic criteria for B-cell acute lymphoblastic leukemia: the malignant cells had L3 morphology, bore B-cell markers, and carried the specific t(8;14) translocation. The leukemic cells of one patient were tetrasomic for 1q, and those of the other patient showed several separ...

journal_title：Cancer

authors： Morris CM,Fitzgerald PH,Neville MA,Wyld PJ,Beard ME

更新日期：1984-07-01 00:00:00

abstract：:Thrombocytosis above 40.0 X 10(4)/mm3 occurred in five of six (83%) patients with malignant mesothelioma. In contrast, the incidence of thrombocytosis was 7.5% in patients with lung adenocarcinoma, 12.5% in squamous cell carcinoma, 5.1% in small cell carcinoma, and 41.7% in large cell carcinoma, respectively. The plat...

journal_title：Cancer

authors： Nakano T,Fujii J,Tamura S,Hada T,Higashino K

更新日期：1986-10-15 00:00:00

abstract：BACKGROUND:To the authors' knowledge, the long term follow-up of patients with carcinoma in situ of the urinary bladder is limited. METHODS:The authors studied 138 patients diagnosed with urothelial carcinoma in situ of the bladder at the Mayo Clinic between 1972-1979. All the histologic slides were reviewed and fulfi...

journal_title：Cancer

authors： Cheng L,Cheville JC,Neumann RM,Leibovich BC,Egan KS,Spotts BE,Bostwick DG

更新日期：1999-06-01 00:00:00

abstract：:A retrospective study of all cases of seminoma treated at Roswell Park Memorial Institute from 1970 through 1979 was conducted. Fifty-six evaluable patients treated initially with radiation therapy were seen during this period, and the overall survival rate at an average follow-up period of 52 months was 82%. The surv...

journal_title：Cancer

authors： Huben RP,Williams PD,Pontes JE,Panahon AM,Murphy GP

更新日期：1984-04-01 00:00:00

abstract：:The clonal growth pattern of bone marrow and peripheral blood cells from 16 patients with clinically suspected chronic myelogenous leukemia (CML) was evaluated in the double-layer agar system. Cytogenetic studies were performed on parallel marrow and peripheral blood samples. In four cases a unique growth pattern emer...

journal_title：Cancer

authors： Selvaggi S,Wolman SR,Bornstein S,Edinger F

更新日期：1984-12-15 00:00:00

abstract：:Pretreatment factors of prognostic value were sought in 54 consecutively treated cases of adult acute myelogenous leukemia. Twenty of 37 patients with a good (greater than 50%) pretreatment Karnofsky performance status (P.S.) achieved complete remission (C.R.), while only 1/17 with a poor P.S. achieved C.R. This diffe...

journal_title：Cancer

authors： Kansal V,Omura GA,Soong SJ

更新日期：1976-07-01 00:00:00

abstract：BACKGROUND:Recent clinical trials have documented activity for combinations of chemotherapeutic agents that target the microtubular apparatus in patients with hormone-refractory prostate cancer. Taxol has a novel antimicrotubular mechanism, acting by stabilizing polymerized tubulin. METHODS:Twenty-three patients with ...

journal_title：Cancer

authors： Roth BJ,Yeap BY,Wilding G,Kasimis B,McLeod D,Loehrer PJ

更新日期：1993-10-15 00:00:00

abstract：:Randomized breast cancer screening trials are helpful in establishing evidence of benefit when they yield statistically significant results. The results of individual randomized screening trials can vary greatly depending on the quality of the images, the frequency of screening, compliance, contamination, sample size,...

journal_title：Cancer

authors： Smart CR

更新日期：1994-07-01 00:00:00

abstract：:Historically coal mining populations have been reported to have elevated stomach cancer incidence rates. To identify which factors might be associated with cases who reside in these high risk areas, and specifically if particulate exposures from coal mining and coal utilization are associated with risk, a mining area ...

journal_title：Cancer

authors： Weinberg GB,Kuller LH,Stehr PA

更新日期：1985-08-01 00:00:00

abstract：:Malignant struma ovarii is a very rare tumor, consisting of a struma ovarii with malignant change. Only 17 examples with metastases have previously been reported. We present a case which involved both ovaries and produced multiple metastases. Microscopy and ultrastructure were identical to a mixed papillary and follic...

journal_title：Cancer

authors： Pardo-Mindan FJ,Vazquez JJ

更新日期：1983-01-15 00:00:00

abstract：:Merkel cell carcinoma (MCC) is a relatively rare cutaneous malignancy that occurs predominantly in the older white population. The incidence of MCC appears to have tripled during the past 20 years; an increase that is likely to continue because of the growing number of older Americans. The pathogenesis of MCC remains ...

journal_title：Cancer

authors： Bichakjian CK,Lowe L,Lao CD,Sandler HM,Bradford CR,Johnson TM,Wong SL

更新日期：2007-07-01 00:00:00

abstract：:Giant cell tumors of synovium (pigmented villonodular synovitis) involving the vertebral column recently have been seen in two women: the third and fourth cases to be reported in the English-language literature. Unlike the previously reported cases, both these tumors grew outside the dura and produced symptoms of spin...

journal_title：Cancer

authors： Weidner N,Challa VR,Bonsib SM,Davis CH Jr,Carrol TJ Jr

更新日期：1986-05-15 00:00:00

abstract：:The mitogen-activated protein kinase/extracellular signal-regulated (MAPK/ERK) pathway is activated by upstream genomic events and/or activation of multiple signaling events in which information coalesces at this important nodal pathway point. This pathway is tightly regulated under normal conditions by phosphatases a...

journal_title：Cancer

authors： Burotto M,Chiou VL,Lee JM,Kohn EC

更新日期：2014-11-15 00:00:00

abstract：BACKGROUND:Hepatocellular carcinoma (HCC) occurs more frequently in patients with hepatitis C virus (HCV)-related chronic liver disease than those with hepatitis B virus-related disease. It is important to assess the factors affecting the development of HCC. METHODS:A long term follow-up study involving patients with ...

journal_title：Cancer

authors： Aizawa Y,Shibamoto Y,Takagi I,Zeniya M,Toda G

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Intralesional radioimmunotherapy (RAIT) may improve the management of malignant gliomas whose prognosis is, at present, very poor. Current treatment modalities (e.g., surgery, radiotherapy, and chemotherapy) may prolong survival by a few months but cannot prevent tumor recurrence. METHODS:Following one or m...

journal_title：Cancer

authors： Riva P,Arista A,Tison V,Sturiale C,Franceschi G,Spinelli A,Riva N,Casi M,Moscatelli G,Frattarelli M

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:There is controversy regarding the effect of age on breast carcinoma, and previous analyses have often excluded the most elderly patients as well as those with advanced cancers. This study assessed treatment variations and outcome in relation to age for a complete series of patients who presented with breast...

journal_title：Cancer

authors： Golledge J,Wiggins JE,Callam MJ

更新日期：2000-01-15 00:00:00

abstract：BACKGROUND:Kaiser Permanente (KP) is a large health maintenance organization (HMO) operating in 14 states and caring for 8,000,000 members in hundreds of facilities staffed by thousands of physicians and support personnel. Cancer care is provided to these KP members as part of the health care package. METHODS:KP insur...

journal_title：Cancer

authors： Glass A

更新日期：1998-05-15 00:00:00

abstract：BACKGROUND:Diabetes is positively associated with various cancers, but its relationship with tumors of the esophagus/esophagogastric junction remains unclear. METHODS:Data were harmonized across 13 studies in the International Barrett's and Esophageal Adenocarcinoma Consortium, comprising 2309 esophageal adenocarcinom...

journal_title：Cancer

authors： Petrick JL,Li N,Anderson LA,Bernstein L,Corley DA,El Serag HB,Hardikar S,Liao LM,Liu G,Murray LJ,Rubenstein JH,Schneider JL,Shaheen NJ,Thrift AP,van den Brandt PA,Vaughan TL,Whiteman DC,Wu AH,Zhao WK,Gammon MD,Coo

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Primary malignant splenic neoplasms are rare tumors. Apart from involvement of the spleen by malignant lymphoma, hemangiosarcoma is the most common form of primary malignant neoplasm in the spleen. The diagnosis often is made at autopsy or after spontaneous splenic rupture. The prognosis is usually poor, and...

journal_title：Cancer

authors： Søndenaa K,Heikkilä R,Nysted A,Søreide JA,Odegaard H,Pollard ML,Holter J

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Patients with bulky laryngopharyngeal masses and a relative or absolute contraindication to general anesthesia present diagnostic difficulties. In the current study, the authors assessed the utility of transcutaneous ultrasound-guided Tru-Cut biopsy (USGTCB) under local anesthesia in such individuals. METHO...

journal_title：Cancer

authors： Ansarin M,De Fiori E,Preda L,Maffini F,Bruschini R,Calabrese L,Jereczek-Fossa BA,Chiesa F,Bellomi M

更新日期：2007-06-01 00:00:00

abstract：:Twenty-nine patients treated with adjuvant chemotherapy for carcinoma of the breast were evaluated for frequency and amount of weight gained during treatment. No difference with respect to age, menopausal status, estrogen receptor status, nodal status, biochemical parameters, or treatment regimen (CMF versus CMFVP) we...

journal_title：Cancer

authors： Huntington MO

更新日期：1985-08-01 00:00:00

abstract：:Thirty-eight metastatic breast cancer patients were treated with aminoglutethimide. All patients had progressive metastatic disease following initial response to Tamoxifen therapy. Thirty-two patients were evaluable for response, of these, two patients (6%) had complete remission, 13 patients (41%) had partial respons...

journal_title：Cancer

authors： Buzdar AU,Powell KC,Legha SS,Blumenschein GR

更新日期：1982-11-01 00:00:00

abstract：BACKGROUND:Angiogenesis is essential for tumor growth, progression, and metastases. Microvessel density (MVD), a measure of tumor angiogenesis, has been found to have prognostic significance in many tumor types for predicting metastasis and survival. METHODS:Between 1979-1989, 56 cases of FIGO Clinical Stage I and II ...

journal_title：Cancer

authors： Kaku T,Hirakawa T,Kamura T,Amada S,Kinukawa N,Kobayashi H,Sakai K,Ariyoshi K,Sonoda K,Nakano H

更新日期：1998-10-01 00:00:00

abstract：:The survival of 78 patients with resected non-small cell lung cancer entered in prospective, randomized investigational trials is compared to that of a population-based group of control patients not included in such trials. The survival of trial patients is significantly better than that of controls (P less than 0.001...

journal_title：Cancer

authors： Davis S,Wright PW,Schulman SF,Hill LD,Pinkham RD,Johnson LP,Jones TW,Kellogg HB Jr,Radke HM,Sikkema WW

更新日期：1985-10-01 00:00:00