Abstract:
:Malignant struma ovarii is a very rare tumor, consisting of a struma ovarii with malignant change. Only 17 examples with metastases have previously been reported. We present a case which involved both ovaries and produced multiple metastases. Microscopy and ultrastructure were identical to a mixed papillary and follicular carcinoma of the thyroid gland. Characteristic ultrastructural features of malignant struma ovarii are: microvilli on the surface and in the cytoplasmatic vacuoles; oncocytic transformation of cytoplasm of some cells; and presence of electron dense, granular and crystalline material (colloid) in the follicles and vacuoles. The patient's thyroid was normal. We conclude that malignant struma ovarii can only be diagnosed wheb a carcinoma arising in the thyroid gland can be excluded. Ultrastructure examination may provide useful diagnostic features separating malignant struma ovarii from strumal carcinoid and serous adenocarcinoma.
journal_name
Cancerjournal_title
Cancerauthors
Pardo-Mindan FJ,Vazquez JJdoi
10.1002/1097-0142(19830115)51:2<337::aid-cncr28205subject
Has Abstractpub_date
1983-01-15 00:00:00pages
337-43issue
2eissn
0008-543Xissn
1097-0142journal_volume
51pub_type
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