Cancer risks among Missouri farmers.

abstract：BACKGROUND:Thymic malignancies are rare tumors. The insulin-like growth factor-1 (IGF-1)/IGF-1 receptor (IGF-1R) system is involved in the development of the thymus. IGF-1R expression in thymic epithelial malignancies is unknown. METHODS:The authors investigated the expression of IGF-1R and phosphorylated AKT serine 4...

journal_title：Cancer

authors： Zucali PA,Petrini I,Lorenzi E,Merino M,Cao L,Di Tommaso L,Lee HS,Incarbone M,Walter BA,Simonelli M,Roncalli M,Santoro A,Giaccone G

更新日期：2010-10-15 00:00:00

abstract：BACKGROUND:Children of different racial/ethnic backgrounds have varying risks of cancer. However, to the authors' knowledge, few studies to date have examined cancer occurrence in children of mixed ancestry. METHODS:This population-based case-control study examined cancer among children aged <15 years using linked can...

journal_title：Cancer

authors： Chow EJ,Puumala SE,Mueller BA,Carozza SE,Fox EE,Horel S,Johnson KJ,McLaughlin CC,Reynolds P,Von Behren J,Spector LG

更新日期：2010-06-15 00:00:00

abstract：BACKGROUND:BRAF inhibitors are effective in melanoma and other cancers with BRAF mutations; however, patients ultimately develop therapeutic resistance through the activation of alternative signaling pathways such as RAF/RAS or MET. The authors hypothesized that combining the BRAF inhibitor vemurafenib with either the ...

journal_title：Cancer

authors： Janku F,Sakamuri D,Kato S,Huang HJ,Call SG,Naing A,Holley VR,Patel SP,Amaria RN,Falchook GS,Piha-Paul SA,Zinner RG,Tsimberidou AM,Hong DS,Meric-Bernstam F

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND:Ovarian serous tumors of low malignant potential (STLMP) occasionally progress; a small percentage of patients die of the tumor. There is no known way to predict which tumors will progress. METHODS:Forty STLMP were analyzed by DNA flow cytometry and compared with 26 serous carcinomas. RESULTS:Forty percent...

journal_title：Cancer

authors： Seidman JD,Norris HJ,Griffin JL,Hitchcock CL

更新日期：1993-06-15 00:00:00

abstract：:Eight hundred sixty-five patients with a microscopically curative resection for carcinoma of the lung were accepted for study, none of whom were excluded from analysis. Adjuvant therapy was randomly assigned about the tenth to 14th postoperative day; 432 patients (treated) were to receive CCNU and hydroxyurea for one ...

journal_title：Cancer

authors： Shields TW,Higgins GA Jr,Humphrey EW,Matthews MJ,Keehn RJ

更新日期：1982-11-01 00:00:00

abstract：:Front loading chemotherapy using methotrexate (200 mg/m2) alone or methotrexate (200 mg/m2) with cisplatin (20 mg/m2 daily for 5 days) was used in epidermoid carcinoma of esophagus. Evaluation after two courses showed objective response of 50% or greater in 48% of patients with methotrexate alone. Response rate was in...

journal_title：Cancer

authors： Advani SH,Saikia TK,Swaroop S,Ramakrishnan G,Nair CN,Dinshaw KA,Sharma S,Vyas JJ,Desai PB

更新日期：1985-10-01 00:00:00

abstract：BACKGROUND:The objective of this study was to determine whether standardized treatment of germ cell tumors (GCTs) could overcome sociodemographic factors limiting patient care. METHODS:The records of all patients undergoing primary treatment for GCTs at both a public safety net hospital and an academic tertiary care c...

journal_title：Cancer

authors： Chertack N,Ghandour RA,Singla N,Freifeld Y,Hutchinson RC,Courtney K,Bowman IA,Arafat W,Meng X,Moore JA,Aydin AM,Sagalowsky AI,Margulis V,Lotan Y,Woldu SL,Bagrodia A

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Pretreatment serum prostate specific antigen (PSA) level is a powerful prognostic factor for clinically localized prostate carcinoma. The traditional prognostic factors, T classification and Gleason score, appear to have been relegated to a minor position. This study was conducted to evaluate the relative pr...

journal_title：Cancer

authors： Zagars GK,Pollack A,von Eschenbach AC

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:A new, internationally accepted histologic classification of renal cell carcinoma (RCC) and a new edition of the TNM staging system were introduced in 1997. In the latter, there was a dramatic change in the pT classification of organ-confined renal cancer in which the break point between category pT1 and pT2...

journal_title：Cancer

authors： Moch H,Gasser T,Amin MB,Torhorst J,Sauter G,Mihatsch MJ

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:Some growth factors may promote tumor growth by affecting tumor angiogenesis. The angiogenic growth factor, pleiotrophin, was demonstrated previously in human breast carcinoma tissues; however, the pattern of pleiotrophin expression in normal breast tissues has not been established. METHODS:The expression o...

journal_title：Cancer

authors： Garver RI Jr,Radford DM,Donis-Keller H,Wick MR,Milner PG

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:Patients with aggressive non-Hodgkin lymphoma (NHL) require intensive and extensive therapy, which seems impracticable in elderly patients due to hematologic and extrahematologic toxicity. Consequent dose reduction and therapy attenuation can reduce treatment-related toxicity but also decreases therapeutic e...

journal_title：Cancer

authors： Rigacci L,Carpaneto A,Alterini R,Carrai V,Bernardi F,Bellesi G,Longo G,Bosi A,Rossi Ferrini P

更新日期：2003-01-01 00:00:00

abstract：:Fourteen examples of intravenous leiomyomatosis in the FIP files were studied. Growth beyond the uterus occurred in 10 of the 14 examples, largely in vessels in the broad ligament and in uterine and iliac veins. Metastasis to the heart occurred in 1 example. The study provides evidence that is consistent with both the...

journal_title：Cancer

authors： Norris HJ,Parmley T

更新日期：1975-12-01 00:00:00

abstract：:Only three previous reports on the ultrastructural appearance of tibial adamantinoma have been found among some 120 cases of this tumor reported in the literature. The tumor in our case is less differentiated than the cases previously reported. We believe it is of epithelial character and the possibilities of its hist...

journal_title：Cancer

authors： Yoneyama T,Winter WG,Milsow L

更新日期：1977-09-01 00:00:00

abstract：BACKGROUND:The use of docetaxel prolongs survival for patients with castrate-resistant prostate cancer (CRPC). Inhibition of vascular endothelial growth factor (VEGF) with bevacizumab may further enhance the antitumor effect of docetaxel and estramustine in patients with CRPC. METHODS:This cooperative group trial enro...

journal_title：Cancer

authors： Picus J,Halabi S,Kelly WK,Vogelzang NJ,Whang YE,Kaplan EB,Stadler WM,Small EJ,Cancer and Leukemia Group B.

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:To describe continuing care and rehabilitation needs of cancer patients, a longitudinal design (6 months) was performed among patients 50 years of age and older with solid tumors. The study examined how age, type of treatment, site of cancer, and symptom experience affect physical functioning and their menta...

journal_title：Cancer

authors： Given CW,Given BA,Stommel M

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:Thyroid carcinomas historically have been divided into two groups according to their presumedly separate embryonic origins: those of neuroectodermal derivation (parafollicular or medullary carcinoma [MCT]) and those of foregut endodermal origin (follicular and papillary carcinomas). The validity of this conc...

journal_title：Cancer

authors： Kovacs CS,Masé RM,Kovacs K,Nguyen GK,Chik CL

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:Radiofrequency (RF)-induced tissue coagulation represents a new approach for the thermal destruction of tumors within the liver. The purpose of the current study was to 1) assess technique safety; 2) determine the extent and evolution of induced cellular damage; and 3) correlate the observed pathologic effec...

journal_title：Cancer

authors： Goldberg SN,Gazelle GS,Compton CC,Mueller PR,Tanabe KK

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:Irinotecan-based chemotherapy regimens are 1 option for treatment of metastatic colorectal cancer (mCRC). The authors report the safety and efficacy of such regimens in elderly patients using a large phase III trial (bolus, infusional, or capecitabine with camptostar-celecoxib [BICC-C]) cohort. METHODS:In p...

journal_title：Cancer

authors： Jackson NA,Barrueco J,Soufi-Mahjoubi R,Marshall J,Mitchell E,Zhang X,Meyerhardt J

更新日期：2009-06-15 00:00:00

abstract：:Actuarial progression-free survival rate at 5 years of a series of 34 patients with medulloblastoma treated by combined surgery, radiotherapy, and chemotherapy was 71%. No relapses were observed in 14 patients followed for more than 5 years. Treatment consisted of a short postoperative course of vincristine (VCR) and ...

journal_title：Cancer

authors： Bellani FF,Gasparini M,Lombardi F,Zucali R,Luccarelli G,Migliavacca F,Moise S,Nicola G

更新日期：1984-11-01 00:00:00

abstract：BACKGROUND:Recent clinical studies have demonstrated that tumor angiogenesis is a potent prognostic indicator for breast cancer patients. The quantitation of endothelial growth factors is thought to be useful to assess angiogenic phenotype in the tumor. Among the many new endothelial growth factors, vascular endothelia...

journal_title：Cancer

authors： Toi M,Kondo S,Suzuki H,Yamamoto Y,Inada K,Imazawa T,Taniguchi T,Tominaga T

更新日期：1996-03-15 00:00:00

abstract：:The National Wilms' Tumor Study (NWTS) was initiated in 1969. One of its objectives was to modulate treatments according to risk factors to minimize the number and severity of treatment-related short-term and long-term iatrogenic complications. The NWTS has therefore incorporated a Long Term Follow-up Study (LTFS) wit...

journal_title：Cancer

authors： Evans AE,Norkool P,Evans I,Breslow N,D'Angio GJ

更新日期：1991-01-15 00:00:00

abstract：:All patients with a diagnosis of cutaneous malignant melanoma (CMM) in Western Australia from 1980 to 1981 were observed for up to 6 years to determine vital status and to detect the development of local recurrences of the primary lesion. Approximately 35% of all patients had their tumors excised with surgical margins...

journal_title：Cancer

authors： Heenan PJ,English DR,Holman CD,Armstrong BK

更新日期：1992-01-15 00:00:00

abstract：BACKGROUND:It is believed that atypical cells identified by nipple duct lavage (NDL) indicate an increased risk for breast carcinoma similar to atypical ductal hyperplasia diagnosed by tissue biopsy, but many basic performance characteristics of NDL currently are undefined. METHODS:NDL was performed in 108 patients un...

journal_title：Cancer

authors： Johnson-Maddux A,Ashfaq R,Cler L,Naftalis E,Leitch AM,Hoover S,Euhus DM

更新日期：2005-03-15 00:00:00

abstract：BACKGROUND:Previously published studies concerning autopsy findings in ovarian cancer failed to consider the broad differences in factors that influence the course of disease. Furthermore, those studies were conducted when the currently accepted standards in diagnostics and therapy had not been fully established. The o...

journal_title：Cancer

authors： Güth U,Huang DJ,Bauer G,Stieger M,Wight E,Singer G

更新日期：2007-09-15 00:00:00

abstract：:The case history of a woman with a "female adnexal tumor of probable Wolffian origin" is described in which the neoplasm recurred three times during a 16-year interval and responded with prolonged remission after repeated surgical excision and radiotherapy. Ultrastructural data are given to support the Wolffian nature...

journal_title：Cancer

authors： Brescia RJ,Cardoso de Almeida PC,Fuller AF Jr,Dickersin GR,Robboy SJ

更新日期：1985-09-15 00:00:00

abstract：BACKGROUND:It is important for clinicians, researchers, and others who shape public health policy to understand the demographic correlates and psychologic factors that drive health behaviors, such as screening for early detection of cancer, particularly among individuals at high risk for developing the disease. METHOD...

journal_title：Cancer

authors： Beebe-Dimmer JL,Wood DP Jr,Gruber SB,Chilson DM,Zuhlke KA,Claeys GB,Cooney KA

更新日期：2004-04-01 00:00:00

abstract：:Two hundred-eighty patients were randomized to receive either BCNU, hydroxyurea and imidazole carboxamide (BHD), BHD plus levamisole, or high-dose DTIC plus actinomycin D. There was no difference in response rate in the three groups (24%, 25% and 22%). Females responded better than males and, as expected, those with a...

journal_title：Cancer

authors： Costanzi JJ,Fletcher WS,Balcerzak SP,Taylor S,Eyre HJ,O'Bryan RM,Al-Sarraf M,Frank J

更新日期：1984-02-15 00:00:00

abstract：BACKGROUND:Obesity has been associated with inferior outcomes in operable breast cancer, but the relation between body mass index (BMI) and outcomes by breast cancer subtype has not been previously evaluated. METHODS:The authors evaluated the relation between BMI and outcomes in 3 adjuvant trials coordinated by the Ea...

journal_title：Cancer

authors： Sparano JA,Wang M,Zhao F,Stearns V,Martino S,Ligibel JA,Perez EA,Saphner T,Wolff AC,Sledge GW Jr,Wood WC,Fetting J,Davidson NE

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:The lack of comparable metrics to evaluate prevention and early detection patient navigation programs impeded the ability to identify best practices. METHODS:The Prevention and Early Detection Workgroup of the Patient Navigation Leadership Summit was charged with making recommendations for common clinical m...

journal_title：Cancer

authors： Battaglia TA,Burhansstipanov L,Murrell SS,Dwyer AJ,Caron SE,Prevention and Early Detection Workgroup, National Patient Navigation Leadership Summit.

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:The objective of this study was to assess whether coregistered whole brain (WB) magnetic resonance imaging-positron emission tomography (MRI-PET) would increase the number of correctly upstaged patients compared with WB PET-computed tomography (PET-CT) plus dedicated brain MRI in patients with nonsmall cell ...

journal_title：Cancer

authors： Yi CA,Lee KS,Lee HY,Kim S,Kwon OJ,Kim H,Choi JY,Kim BT,Hwang HS,Shim YM

更新日期：2013-05-15 00:00:00