Combination chemotherapy plus levamisole in the treatment of disseminated malignant melanoma. A Southwest Oncology Group study.

abstract：:This report describes a unique palliative approach of radical surgical debridement for uncontrollable, recurrent pelvic tumors ulcerating through the perineum. All conservative treatment attempts with radiotherapy and chemotherapy had failed. Seven patients have been treated with resection of the tumor including a por...

journal_title：Cancer

authors： Temple WJ,Ketcham AS

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:The authors originally demonstrated the tissue-specific expression of the rab3A gene in the mouse brain. In the current study, they analyze the activity of this gene in fresh human tumors associated with neuronal phenotype compared with normal and malignant cells from other origins. METHODS:The authors stud...

journal_title：Cancer

authors： Culine S,Rousseau-Merck MF,Honoré N,Nezelof C,Olofsson B

更新日期：1992-11-15 00:00:00

abstract：BACKGROUND:Cell cycle proteins are important markers in predicting tumor behavior in urothelial carcinoma of the bladder. The objectives of this study were 1) to determine the expression levels of some of those markers in a series of patients with bladder carcinoma, 2) to define their value in distinguishing T1a (minim...

journal_title：Cancer

authors： Mhawech P,Greloz V,Oppikofer C,Szalay-Quinodoz I,Herrmann F

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:This study was performed to evaluate the use of the 1992 International Union Against Cancer (UICC)/American Joint Committee on Cancer (AJCC) T categories for localized prostate cancer treated with radiation therapy and to compare the prognostic power of this system with the Whitmore-Jewett scheme. METHODS:T...

journal_title：Cancer

authors： Zagars GK,Geara FB,Pollack A,von Eschenbach AC

更新日期：1994-04-01 00:00:00

abstract：:The American Cancer Society estimates that nearly a million new cases of cancer will occur and that approximately a half million lives will be lost in 1987. These figures may double by the year 2000 primarily because of our aging population, with age being the leading risk factor for cancer. It is believed that the ma...

journal_title：Cancer

authors： Williams PA,Williams M

更新日期：1988-06-01 00:00:00

abstract：:Forty-four patients with advanced carcinoma of the head and neck were treated with cyclophosphamide, 400 mg/m2 plus BCNU, 100 mg/m2 day 1 followed by adriamycin 40 mg/m2 day 2, with therapy repeated every 4 weeks. Of 31 evaluable patients, there were 1 complete response, and 10 partial responses (35%). Four of 8 patie...

journal_title：Cancer

authors： Presant CA,Ratkin G,Klahr C,Brown C

更新日期：1979-11-01 00:00:00

abstract：:The hepatic histopathology was studied in 125 patients with Hodgkin's disease to determine whether there are any features other than Reed-Sternberg (RS) cells that might aid in the diagnosis of hepatic involvement by the neoplastic process. Liver biopsy specimens from 41 patients with Hodgkin's disease in the liver we...

journal_title：Cancer

authors： Dich NH,Goodman ZD,Klein MA

更新日期：1989-11-15 00:00:00

abstract：:Six cases of desmoplastic melanoma were studied by light and electron microscopy. The tumors fulfilled one or more of the following criteria: (1) having the presence of atypical intraepidermal melanocytic proliferation bordering the primary lesions; (2) an antecedent history of melanoma at the site of recurrence; (3) ...

journal_title：Cancer

authors： DiMaio SM,Mackay B,Smith JL Jr,Dickersin GR

更新日期：1982-12-01 00:00:00

abstract：BACKGROUND:Posttransplant lymphoproliferative disorder (PTLD) is a life-threatening complication of solid organ transplantation. Histologic heterogeneity and a lack of treatment standards have made evaluating clinical outcomes in specific patient populations difficult. This systematic literature review investigated the...

journal_title：Cancer

authors： Koff JL,Li JX,Zhang X,Switchenko JM,Flowers CR,Waller EK

更新日期：2018-06-01 00:00:00

abstract：:Primary lymphomas of the small intestine (PIL) show definite racial and geographic distribution. Clinical and laboratory data on 132 patients with PIL treated and followed up over a 14-year period in Baghdad, Iraq, are presented. Based on the pattern of involvement of the bowel and the histopathologic appearance of th...

journal_title：Cancer

authors： Al-Bahrani ZR,Al-Mondhiry H,Bakir F,Al-Saleem T

更新日期：1983-11-01 00:00:00

abstract：:The clinical findings in 262 patients with melanoma were correlated with an assessment of their cellular-mediated immunity by delayed-type hypersensitivity (DTH) skin tests, by lymphocyte blastogenesis, and by leukocyte enumerations. Patients with systemic metastases (stage IV) and those with evidence of tumor burden ...

journal_title：Cancer

authors： Pritchard DJ,Ritts RE Jr,Taylor WF,Miller GC

更新日期：1978-06-01 00:00:00

abstract：:A ganglioneuroma with areas of melanosis was resected from the cerebellum of a 6.5-year-old girl. At 2.5 years of age, she was diagnosed to have cerebellar neuroblastoma, which was incompletely resected and then radiated. Histologic, ultrastructural, and immunocytochemical studies undertaken on tissue from both stages...

journal_title：Cancer

authors： de Chadarévian JP,Montes JL,O'Gorman AM,Freeman CR

更新日期：1987-01-01 00:00:00

abstract：:The authors report the accuracy of mammographically guided fine-needle aspiration (FNA) for the diagnosis of nonpalpable breast lesions in a series of 71 patients. Each mammographically guided FNA was immediately followed by hookwire localization and open biopsy. Seven malignancies were identified cytologically, but t...

journal_title：Cancer

authors： Layfield LJ,Parkinson B,Wong J,Giuliano AE,Bassett LW

更新日期：1991-11-01 00:00:00

abstract：:The effect of multimodal immunotherapy was studied in rats bearing primary gastrointestinal tumors induced by 1,2-dimethylhydrazine dihydrochloride. Multimodal immune manipulation consisted of combinations of splenectomy, C. parvum, unblocking serum, unblocked lymphoid cells, and levamisole. Such immunologic intervent...

journal_title：Cancer

authors： Bansal BR,Mobini J,Bansal SC

更新日期：1978-11-01 00:00:00

abstract：BACKGROUND:Nodal status is one of the most important prognostic factors for distal bile duct cancer. The pattern of lymphatic spread of distal bile duct cancer was analyzed by determining the frequency of involvement of various lymph nodes. MATERIALS AND METHODS:From 1973 to 1991, 29 patients with distal bile duct can...

journal_title：Cancer

authors： Kayahara M,Nagakawa T,Ueno K,Ohta T,Takeda T,Miyazaki I

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND:Secondary acute myeloid leukemia (AML) after treatment with epipodophyllotoxins is being observed with increased frequency. Therapeutic options are limited for patients with secondary AML and the role of bone marrow transplantation is unclear. METHODS:The authors report the treatment outcome of a cohort of ...

journal_title：Cancer

authors： Sandler ES,Friedman DJ,Mustafa MM,Winick NJ,Bowman WP,Buchanan GR

更新日期：1997-03-01 00:00:00

abstract：:In a 10-year incidence survey of breast cancer in the City of Boston, 14 cases in American Chinese women were observed, while approximately 13 were expected on the basis of age-specific incidence in the white population. In Hawaii, on the other hand, while breast cancer incidence rates for ethnic Chinese are approxima...

journal_title：Cancer

authors： Trichopoulos D,Yen S,Brown J,Cole P,MacMahon B

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:Malignant cells exhibit increased glycolytic metabolism, and in many cases increased glucose transporter gene expression. The authors hypothesized that GLUT1 glucose transporter expression is increased in colorectal carcinoma, and that the degree of expression might have prognostic significance. METHODS:GLU...

journal_title：Cancer

authors： Haber RS,Rathan A,Weiser KR,Pritsker A,Itzkowitz SH,Bodian C,Slater G,Weiss A,Burstein DE

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:Preclinical and clinical data suggest that both leucovorin (LV) and interferon (IFN) can augment the cytotoxic effects of 5-fluorouracil (5-FU). Based on the rationale of biochemical double modulation, the current Phase II study was undertaken. METHODS:Thirty-two previously untreated patients with advanced ...

journal_title：Cancer

authors： Scheithauer W,Pfeffel F,Kornek G,Marczell A,Wiltschke C,Funovics J

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:Nonsteroidal anti-inflammatory drugs (NSAIDs) may prevent the development of cancer by inhibiting cyclooxygenase (COX) enzymes, which are involved in carcinogenesis. Therefore, the authors of this report examined the association between NSAID use and the risk of squamous cell carcinoma (SCC), basal cell carc...

journal_title：Cancer

authors： Johannesdottir SA,Chang ET,Mehnert F,Schmidt M,Olesen AB,Sørensen HT

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Two similarly effective treatment options exist for managing clinical low volume Stage II nonseminomatous germ cell testis tumors (NSGCT). Primary retroperitoneal lymph node dissection (RPLND) (with immediate adjuvant chemotherapy or chemotherapy at relapse) and primary chemotherapy have resulted in similar ...

journal_title：Cancer

authors： Baniel J,Roth BJ,Foster RS,Donohue JP

更新日期：1995-06-15 00:00:00

abstract：:For men diagnosed with clinically localized prostate cancer, definitive therapy with radical prostatectomy, external beam radiation therapy, or brachytherapy offers a high chance of cure. Currently, there are insufficient data to recommend 1 treatment approach over another, leaving physicians and patients to decide ba...

journal_title：Cancer

authors： Nguyen CT,Zelefsky MJ,Kattan MW

更新日期：2009-07-01 00:00:00

abstract：:Although clinically evident thyroid carcinoma is not a frequent neoplasm (incidence 2.7 per 100,000 persons in La Plata, Argentina), occult carcinomas are present in a high proportion of the population, but there are marked differences along geographical lines. The purpose of the present study is to establish the prev...

journal_title：Cancer

authors： Ottino A,Pianzola HM,Castelletto RH

更新日期：1989-07-15 00:00:00

abstract：BACKGROUND:Pretreatment serum prostate specific antigen (PSA) level is a powerful prognostic factor for clinically localized prostate carcinoma. The traditional prognostic factors, T classification and Gleason score, appear to have been relegated to a minor position. This study was conducted to evaluate the relative pr...

journal_title：Cancer

authors： Zagars GK,Pollack A,von Eschenbach AC

更新日期：1997-04-01 00:00:00

abstract：:In 1988, Californians passed Proposition 99, which raised the tobacco tax from 10 cents to 35 cents and allocated 20% of the resulting revenues, approximately $100 million, for tobacco education and 5% for tobacco-related research. Seventy percent was allocated for health care costs and 5% for the environment. In this...

journal_title：Cancer

authors： Martin CB,Beerline D,Breslow L

更新日期：1998-12-15 00:00:00

abstract：:Giant cell tumors of synovium (pigmented villonodular synovitis) involving the vertebral column recently have been seen in two women: the third and fourth cases to be reported in the English-language literature. Unlike the previously reported cases, both these tumors grew outside the dura and produced symptoms of spin...

journal_title：Cancer

authors： Weidner N,Challa VR,Bonsib SM,Davis CH Jr,Carrol TJ Jr

更新日期：1986-05-15 00:00:00

abstract：BACKGROUND:Because of morphologic similarities, the differential diagnosis of granulocytic sarcoma (GS) in fine-needle aspiration (FNA) specimens includes non-Hodgkin or Hodgkin lymphoma, extramedullary hematopoiesis, poorly differentiated carcinoma, and infection. METHODS:Twenty-six FNAs and 1 pleural effusion fluid ...

journal_title：Cancer

authors： Suh YK,Shin HJ

更新日期：2000-12-25 00:00:00

abstract：:Nineteen patients with locally advanced bladder cancer were treated with irradiation and concomitant 5-fluorouracil intravenous infusion with or without bolus mitomycin. Eighteen of the 19 patients were evaluated for local response. Eleven of the 18 patients (61%) obtained a complete local response within 3 to 6 month...

journal_title：Cancer

authors： Rotman M,Macchia R,Silverstein M,Aziz H,Choi K,Rosenthal J,Braverman A,Laungani GB

更新日期：1987-02-15 00:00:00

abstract：:A total of 289 cases with malignant pleuroperitoneal effusions were reviewed, and their prognosis were analyzed in relation to the following factors: (1) chronologically divided series; (2) previous tumorectomy of the primary lesion; (3) presence or absence of other metastases; (4) site of effusion; (5) site of the pr...

journal_title：Cancer

authors： Yamada S,Takeda T,Matsumoto K

更新日期：1983-01-01 00:00:00

abstract：:Transgenic model systems provide tools for obtaining information that clarifies important relationships between genetic alterations and carcinogenesis. One such relationship is the induction of specific growth factor activities by dominantly acting oncogenes. Using a "transgenic organ" model referred to as mouse prost...

journal_title：Cancer

authors： Thompson TC,Truong LD,Timme TL,Kadmon D,McCune BK,Flanders KC,Scardino PT,Park SH

更新日期：1993-02-01 00:00:00