Hepatic involvement in Hodgkin's disease. Clues to histologic diagnosis.

Abstract:

:The hepatic histopathology was studied in 125 patients with Hodgkin's disease to determine whether there are any features other than Reed-Sternberg (RS) cells that might aid in the diagnosis of hepatic involvement by the neoplastic process. Liver biopsy specimens from 41 patients with Hodgkin's disease in the liver were compared with biopsy specimens from 84 patients without hepatic involvement. Patients with hepatic involvement by Hodgkin's disease are much more likely to have histologic evidence of portal infiltrates larger than 1 mm in diameter (78% versus 1%), acute cholangitis (85% versus 4%), portal edema (90% versus 8%), and portal infiltrates with a predominance of atypical lymphocytes (78% versus 12%) than patients with Hodgkin's disease who do not have hepatic involvement. When these features are observed alone or in combination in a liver biopsy specimen from a patient with proven or suspected Hodgkin's disease, a diligent search for RS cells is indicated, with serial sections and repeat biopsy if necessary.

journal_name

Cancer

journal_title

Cancer

authors

Dich NH,Goodman ZD,Klein MA

doi

10.1002/1097-0142(19891115)64:10<2121::aid-cncr282

subject

Has Abstract

pub_date

1989-11-15 00:00:00

pages

2121-6

issue

10

eissn

0008-543X

issn

1097-0142

journal_volume

64

pub_type

杂志文章

相关文献

CANCER文献大全
  • Intravascular angiomatosis: development and distinction from angiosarcoma.

    abstract::Histologic features similar to those present in angiosarcomas were found in organizing thrombi. Within the thrombi, freely anastomosing small channels, often lined by one or more layers of prominent, occasionally atypical, endothelial cells were noted. Papillary-like projections of organizing thrombus material lined b...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197509)36:3<995::aid-cncr2820360

    authors: Salyer WR,Salyer DC

    更新日期:1975-09-01 00:00:00

  • Assessment of quality of survival in children with medulloblastoma and cerebellar astrocytoma.

    abstract::To determine the quality of survival for children with posterior fossa tumors, comprehensive neuropsychological, behavioral, and academic assessment and physician ratings of functional status were obtained on 15 brain tumor patients (ages 6-19 years) at a median of 20 months post-diagnosis. More than 50% of the childr...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19880915)62:6<1215::aid-cncr2820

    authors: LeBaron S,Zeltzer PM,Zeltzer LK,Scott SE,Marlin AE

    更新日期:1988-09-15 00:00:00

  • Cancer prevention through health promotion. Defining the role of physicians in public health.

    abstract::In recent years a major focus in the delivery of cancer prevention services has been on the actions of physicians in ambulatory care practice. Whereas delivery of these services has increased markedly, it is likely that physician actions overall are not producing expected measurable benefits to whole populations. The ...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/1097-0142(19940815)74:4+<1418::aid-cncr282

    authors: Love RR

    更新日期:1994-08-15 00:00:00

  • Characterization of six cell lines established from human pancreatic adenocarcinomas.

    abstract:BACKGROUND:Six human pancreatic carcinoma cell lines, designated as KMP-1 to KMP-6, were established and maintained in vitro for > 3 years. All were derived from pancreatic ductal adenocarcinomas. The six cell lines originated from either primary pancreatic tumors, metastatic liver tumors, or metastases to lymph nodes....

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0142(19990215)85:4<832::aid-cnc

    authors: Kato M,Shimada Y,Tanaka H,Hosotani R,Ohshio G,Ishizaki K,Imamura M

    更新日期:1999-02-15 00:00:00

  • Typhlitis in childhood cancer.

    abstract:BACKGROUND:Typhlitis is increasingly recognized in children undergoing chemotherapy but is poorly characterized. The authors investigated the demographic, clinical, and imaging (ultrasonography and computed tomography [CT] scans) variables related to the diagnosis, risk, and outcome of typhlitis. METHODS:The authors r...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.21134

    authors: McCarville MB,Adelman CS,Li C,Xiong X,Furman WL,Razzouk BI,Pui CH,Sandlund JT

    更新日期:2005-07-15 00:00:00

  • Ultrasound examination of regional lymph nodes significantly improves early detection of locoregional metastases during the follow-up of patients with cutaneous melanoma: results of a prospective study of 1288 patients.

    abstract:BACKGROUND:In regional lymph node metastasis of cutaneous melanoma, the number and volume of involved lymph nodes are the most important prognostic factors. Several studies have revealed that palpation of the lymphatic drainage area(s) and regional lymph nodes has a high rate of false-negative results during follow-up....

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(20000601)88:11<2534::aid-cncr15>

    authors: Blum A,Schlagenhauff B,Stroebel W,Breuninger H,Rassner G,Garbe C

    更新日期:2000-06-01 00:00:00

  • Uroplakin as a marker for typing metastatic transitional cell carcinoma on fine-needle aspiration specimens.

    abstract:BACKGROUND:Immunohistological markers specific for a single type of epithelium are rare. Recently, urothelium tissue-specific genes were cloned. The genes encoded a family of transmembrane proteins, uroplakins, that are expressed only in urothelial mucosa. Using uroplakin antibodies on paraffin-embedded tissue, a previ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.9032

    authors: Xu X,Sun TT,Gupta PK,Zhang P,Nasuti JF

    更新日期:2001-06-25 00:00:00

  • Treatment of polycythemia vera with hydroxyurea.

    abstract::Thirty-six patients with polycythemia vera were treated with hydroxyurea for 12 to 67 months. Nineteen patients were previously treated with other drugs. In the vast majority of patients, an average dose of 1 g/day was sufficient to control hematocrit value and platelet count. Half of the patients experienced relief o...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19860215)57:4<718::aid-cncr28205

    authors: Sharon R,Tatarsky I,Ben-Arieh Y

    更新日期:1986-02-15 00:00:00

  • Hepatoma in the noncirrhotic liver.

    abstract::The pathologic features, clinical presentation and natural history of hepatocellular carcinoma (HCC) developing in the noncirrhotic liver were studied in 61 patients against a background of 63 patients seen concurrently with HCC complicating cirrhosis. Noncirrhotic HCC had a bimodal age distribution, with females pred...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19881001)62:7<1414::aid-cncr2820

    authors: Smalley SR,Moertel CG,Hilton JF,Weiland LH,Weiand HS,Adson MA,Melton LJ 3rd,Batts K

    更新日期:1988-10-01 00:00:00

  • Alpha-fetoprotein and human chorionic gonadotropin in a patient with a primary intracranial germ cell tumor.

    abstract::A 17 year old man with a primary intracranial germ cell tumor in the pituitary region is reported. Both serum alpha-fetoprotein (AFP) and serum human chorionic gonadotropin (hCG) were found elevated preoperatively. Normal levels of serum AFP and hCG were found after operation and radiotherapy. By indirect immunofluore...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197806)41:6<2315::aid-cncr282041

    authors: Nørgaard-Pedersen B,Lindholm J,Albrechtsen R,Arends J,Diemer NH,Riishede J

    更新日期:1978-06-01 00:00:00

  • Establishment and characterization of a panel of human lung cancer cell lines.

    abstract::The establishment and characterization of 11 human lung cancer cell lines are described in this article. Nine of these cell lines were established over a 5-year period, from 1983 to 1988, from patients treated at the Kingston Regional Cancer Centre. These include eight definite or probable small cell lung cancer (SCLC...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19920415)69:8<2064::aid-cncr2820

    authors: Campling BG,Haworth AC,Baker HM,Greer DL,Holden JJ,Bradley EC,Pym J,Dexter DF

    更新日期:1992-04-15 00:00:00

  • Serum and ascitic fluid levels of interleukin-1, interleukin-6, and tumor necrosis factor-alpha in patients with ovarian epithelial cancer.

    abstract:BACKGROUND:Recent studies have shown that multiple cytokines are secreted by ovarian epithelial cancer cells. Previous studies have shown that the cancer cell lines secrete macrophage colony-stimulating factor (M-CSF), granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-1 (IL-1), interleukin-6 (IL-6)...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19931015)72:8<2433::aid-cncr2820

    authors: Moradi MM,Carson LF,Weinberg B,Haney AF,Twiggs LB,Ramakrishnan S

    更新日期:1993-10-15 00:00:00

  • The prevalence of patients with colorectal carcinoma under care in the U.S.

    abstract:BACKGROUND:Prevalence usually is defined as the proportion of individuals alive who previously had a diagnosis of the disease, regardless of whether the individuals still are receiving treatment or are cured. The objective of this study was to estimate the proportion of elderly patients with colorectal carcinoma (CRC) ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.11631

    authors: Mariotto A,Warren JL,Knopf KB,Feuer EJ

    更新日期:2003-09-15 00:00:00

  • Intrahepatic cholangiocarcinoma with sarcomatous change. Clinicopathologic and immunohistochemical evaluation of seven cases.

    abstract:BACKGROUND:Although there have been a few reports dealing with the sarcomatous changes of intrahepatic cholangiocarcinoma, its clinicopathologic features as well as immunohistochemical nature remain obscure. METHODS:Among 155 cases of intrahepatic cholangiocarcinoma, 7 cases of sarcomatous cholangiocarcinoma were chos...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19930915)72:6<1872::aid-cncr2820

    authors: Nakajima T,Tajima Y,Sugano I,Nagao K,Kondo Y,Wada K

    更新日期:1993-09-15 00:00:00

  • Role of 5-aminolevulinic acid in the detection of urothelial premalignant lesions.

    abstract:BACKGROUND:The authors evaluated the role of 5-aminolevulinic acid (5-ALA)-induced fluorescence endoscopy (AFE) in the detection of flat urothelial lesions in light of the suggestions made for flat neoplastic lesions within the 1999 World Health Organization (WHO) classification of urinary bladder tumors. METHODS:From...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.10821

    authors: Zaak D,Hungerhuber E,Schneede P,Stepp H,Frimberger D,Corvin S,Schmeller N,Kriegmair M,Hofstetter A,Knuechel R

    更新日期:2002-09-15 00:00:00

  • Physician interpretation of genomic test results and treatment selection.

    abstract:BACKGROUND:Genomic testing is increasingly performed in oncology, but concerns remain regarding the clinician's ability to interpret results. In the current study, the authors sought to determine the agreement between physicians and genomic annotators from the Precision Oncology Decision Support (PODS) team at The Univ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.31112

    authors: Brusco LL,Wathoo C,Mills Shaw KR,Holla VR,Bailey AM,Johnson AM,Khotskaya YB,Litzenburger BC,Sanchez NS,Zeng J,Bernstam EV,Eng C,Kee BK,Amaria RN,Routbort MJ,Mills GB,Mendelsohn J,Meric-Bernstam F

    更新日期:2018-03-01 00:00:00

  • Prostate cancer mortality and metastasis under different biopsy frequencies in North American active surveillance cohorts.

    abstract:BACKGROUND:Active surveillance (AS) is an accepted means of managing low-risk prostate cancer. Because of the rarity of downstream events, data from existing AS cohorts cannot yet address how differences in surveillance intensity affect metastasis and mortality. This study projected the comparative benefits of differen...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.32557

    authors: Lange JM,Laviana AA,Penson DF,Lin DW,Bill-Axelson A,Carlsson SV,Newcomb LF,Trock BJ,Carter HB,Carroll PR,Cooperberg MR,Cowan JE,Klotz LH,Etzioni RB

    更新日期:2020-02-01 00:00:00

  • Improved control of cisplatin-induced emesis with high-dose metoclopramide and with combinations of metoclopramide, dexamethasone, and diphenhydramine. Results of consecutive trials in 255 patients.

    abstract::A series of consecutive trials were undertaken to determine whether higher doses of intravenous metoclopramide and combinations of metoclopramide, dexamethasone, and diphenhydramine would improve antiemetic control or decrease treatment-related side effects in patients receiving cisplatin at 120 mg/m2. Metoclopramide ...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/1097-0142(19850201)55:3<527::aid-cncr28205

    authors: Kris MG,Gralla RJ,Tyson LB,Clark RA,Kelsen DP,Reilly LK,Groshen S,Bosl GJ,Kalman LA

    更新日期:1985-02-01 00:00:00

  • Perineural invasion of prostate carcinoma cells is associated with reduced apoptotic index.

    abstract:BACKGROUND:Prostate carcinoma is often associated with perineural (PN) invasion. The common occurrence of this phenomenon has led to speculation regarding the mechanisms of this association, yet to date there have been no studies that clearly define biologic differences between PN and nonperineural (NPN) carcinoma cell...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/(SICI)1097-0142(19960915)78:6<1267::AID-CN

    authors: Yang G,Wheeler TM,Kattan MW,Scardino PT,Thompson TC

    更新日期:1996-09-15 00:00:00

  • Metaanalysis of the accuracy of rapid prescreening relative to full screening of pap smears.

    abstract:BACKGROUND:Efficient quality assurance and improvement measures are essential ingredients in a well organized cytology-based program for cervical carcinoma screening. Various pap smear review procedures, aiming for optimization of accuracy, are described throughout the literature. Evaluation and synthesis of those meth...

    journal_title:Cancer

    pub_type: 杂志文章,meta分析

    doi:10.1002/cncr.10921

    authors: Arbyn M,Schenck U,Ellison E,Hanselaar A

    更新日期:2003-02-25 00:00:00

  • Conservation surgery and irradiation as an alternative to mastectomy in the treatment of clinically favorable breast cancer.

    abstract::The combination of conservation surgery and radiation therapy for early breast cancer is gaining acceptance as an alternative to radical mastectomy. This article reviews the results of randomized trials showing that there is no advantage to a radical mastectomy in patients with early breast cancer. In addition, the ar...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1002/1097-0142(19841201)54:2+<2668::aid-cncr282

    authors: Montague ED,Ames FC,Schell SR,Romsdahl MM

    更新日期:1984-12-01 00:00:00

  • Bone sarcomas associated with Ollier's disease.

    abstract::Of 55 patients with Ollier's disease seen at the Mayo Clinic between 1907 and 1985, 16 had malignant bone neoplasms: 12 chondrosarcomas, two dedifferentiated chondrosarcomas, one chordoma, and one osteosarcoma. One patient had a chondrosarcoma in two different bones. These findings suggest that approximately 30% of pa...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19870401)59:7<1376::aid-cncr2820

    authors: Liu J,Hudkins PG,Swee RG,Unni KK

    更新日期:1987-04-01 00:00:00

  • Characteristics of patients with stage III colon adenocarcinoma who fail to receive guideline-recommended treatment.

    abstract:BACKGROUND:Many patients with stage III colon adenocarcinoma do not receive adjuvant chemotherapy despite the proven survival advantage it offers. To enhance the provision of optimal cancer care, patient characteristics associated with not receiving guideline-adherent treatment must be identified among patients with op...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.25250

    authors: Winget M,Hossain S,Yasui Y,Scarfe A

    更新日期:2010-10-15 00:00:00

  • Comparison of ureteral washing and biopsy specimens in the community setting.

    abstract:BACKGROUND:Ureteral lesions can be difficult to diagnose. The value of ureteral biopsy in addition to ureteral washings has not been defined clearly. METHODS:All ureteral washings and biopsies with follow-up that were performed at a single institution were reviewed. RESULTS:In total, 39 patients underwent ureteral wa...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.21456

    authors: Renshaw AA

    更新日期:2006-02-25 00:00:00

  • Attrition rates, reasons, and predictive factors in supportive care and palliative oncology clinical trials.

    abstract:BACKGROUND:Attrition is common among supportive care/palliative oncology clinical trials. However, to the authors' knowledge, few studies to date have documented the reasons and predictors for dropout. In the current study, the authors' objective was to determine the rate, reasons, and factors associated with attrition...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.27854

    authors: Hui D,Glitza I,Chisholm G,Yennu S,Bruera E

    更新日期:2013-03-01 00:00:00

  • The efficacy of fiberoptic endoscopic examination and biopsy in the detection of early nasopharyngeal carcinoma.

    abstract::Fiberoptic endoscopic examination and biopsy of the nasopharynx was done in 130 patients as a prospective study. They all had elevated titers of antibodies against the viral capsid antigen of Epstein-Barr virus but no symptoms or signs of nasopharyngeal carcinoma. Each underwent a biopsy from six fixed sites in the na...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19910615)67:12<3127::aid-cncr282

    authors: Wei WI,Sham JS,Zong YS,Choy D,Ng MH

    更新日期:1991-06-15 00:00:00

  • Synchronous neoplasms in patients with diminutive colorectal adenomas.

    abstract::The distribution of synchronous neoplasms was retrospectively analyzed in 220 patients undergoing initial colonoscopic evaluation for colorectal neoplasms. In 159 of the 220 patients, an index neoplasm was present in the rectosigmoid region. Of these 159 patients, 32 had an index rectosigmoid adenoma less than 5 mm in...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19871001)60:7<1599::aid-cncr2820

    authors: Tripp MR,Morgan TR,Sampliner RE,Kogan FJ,Protell RL,Earnest DL

    更新日期:1987-10-01 00:00:00

  • Thomsen-Friedenreich antigen presents as a prognostic factor in colorectal carcinoma: A clinicopathologic study of 264 patients.

    abstract:BACKGROUND:Up to now, the expression of the tumor-associated Thomsen-Friedenreich (TF) antigen in colorectal carcinoma has not been thoroughly investigated with particular emphasis on its correlation with established clinicopathologic characteristics and classifications as well as its prognostic relevance. METHODS:For...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:

    authors: Baldus SE,Zirbes TK,Hanisch FG,Kunze D,Shafizadeh ST,Nolden S,Mönig SP,Schneider PM,Karsten U,Thiele J,Hölscher AH,Dienes HP

    更新日期:2000-04-01 00:00:00

  • Patient variables that predict atypical cytology by nipple duct lavage.

    abstract:BACKGROUND:Nipple duct lavage (NDL) may be useful for breast cancer risk stratification. Published guidelines recommend that women with a 5-year Gail risk >/=1.7% should consider undergoing lavage for any fluid-yielding ducts, but it is not known whether increased breast cancer risk or nipple fluid production predict l...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.22538

    authors: Bushnaq ZI,Ashfaq R,Leitch AM,Euhus D

    更新日期:2007-04-01 00:00:00

  • Minute cancers arising de novo in the human large intestine.

    abstract::In order to search for the histogenesis and progression of colorectal cancer, the background mucosas of 18 patients with a single colorectal cancer, apart from familial adenomatosis coli, were studied by a step sectioning method. Three early minute cancers (3-5 mm in diameter) were detected in the apparently normal mu...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19880215)61:4<829::aid-cncr28206

    authors: Kuramoto S,Oohara T

    更新日期:1988-02-15 00:00:00