Synchronous neoplasms in patients with diminutive colorectal adenomas.

Abstract:

:The distribution of synchronous neoplasms was retrospectively analyzed in 220 patients undergoing initial colonoscopic evaluation for colorectal neoplasms. In 159 of the 220 patients, an index neoplasm was present in the rectosigmoid region. Of these 159 patients, 32 had an index rectosigmoid adenoma less than 5 mm in diameter (diminutive), 105 had an index rectosigmoid adenoma greater than or equal to 5 mm in diameter and 22 had an index rectosigmoid adenocarcinoma. Among these patients with different index neoplasms the frequency of synchronous neoplasms was 34%, 53%, and 73%, respectively. The synchronous neoplasm was an adenoma greater than or equal to 5 mm in diameter in 13%, 40%, and 64%, respectively. The synchronous neoplasm was a carcinoma in 0%, 7%, and 5%, respectively. Two or more synchronous neoplasms occurred in 9%, 34%, and 41% of the index neoplasm groups, respectively. Finally, symptoms providing an indication for colonoscopy were present in 31%, 75%, and 86%, respectively. It is concluded that patients with diminutive index adenomas had fewer and smaller synchronous neoplasms (P less than 0.025) than patients with larger adenomas or invasive carcinoma as the index lesion. Thus, total colonoscopy does not appear to be necessary in asymptomatic patients with only diminutive adenomas found at flexible sigmoidoscopy.

journal_name

Cancer

journal_title

Cancer

authors

Tripp MR,Morgan TR,Sampliner RE,Kogan FJ,Protell RL,Earnest DL

doi

10.1002/1097-0142(19871001)60:7<1599::aid-cncr2820

subject

Has Abstract

pub_date

1987-10-01 00:00:00

pages

1599-603

issue

7

eissn

0008-543X

issn

1097-0142

journal_volume

60

pub_type

杂志文章

相关文献

CANCER文献大全
  • Prognostic significance of Wilms tumor gene (WT1) mRNA expression in soft tissue sarcoma.

    abstract:BACKGROUND:There have been several recent reports that Wilms tumor gene (WT1) mRNA is overexpressed in many types of neoplasms, and those results suggested that WT1 has oncogenic properties. The objective of the current study was to evaluate the prognostic significance of WT1 mRNA expression in patients with soft tissu...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.21861

    authors: Sotobori T,Ueda T,Oji Y,Naka N,Araki N,Myoui A,Sugiyama H,Yoshikawa H

    更新日期:2006-05-15 00:00:00

  • Relationships between steroid receptor and epithelial cell proliferation in benign fibrocystic disease of the breast.

    abstract::Tissue specimens from 27 patients with mammary fibrocystic disease were assayed for estrogen (ER) and progestin (PR) receptors. Seventeen patients (63%) had ER-positive lesions (greater than 5 fmol/mg protein). A progression in ER presence was noted from fibrocystic disease (35%) and fibrosing adenosis (50%) to lobula...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19820615)49:12<2534::aid-cncr282

    authors: Jacquemier JD,Rolland PH,Vague D,Lieutaud R,Spitalier JM,Martin PM

    更新日期:1982-06-15 00:00:00

  • Creating alliances to improve cancer prevention and detection among urban medically underserved minority groups. The East Harlem Partnership for Cancer Awareness.

    abstract::The East Harlem Partnership for Cancer Awareness (EHPCA) was formed in 1999 to reduce disparities in cancer screening and prevention among medically underserved minorities residing in a large urban community (East Harlem, New York City) by increasing awareness of cancer risk, prevention, and treatment, and promoting g...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.22153

    authors: Jandorf L,Fatone A,Borker PV,Levin M,Esmond WA,Brenner B,Butts G,Redd WH

    更新日期:2006-10-15 00:00:00

  • Supratentorial ependymomas: prognostic factors and outcome analysis in a retrospective series of 46 adult patients.

    abstract:BACKGROUND:Ependymomas account for 2% of all intracranial tumors in adults. Supratentorial ependymomas are less common than their infratentorial counterparts. To the authors' knowledge to date, the predictive values of surgery, histology, and patient-related prognostic factors for these tumors remain unresolved. The au...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.23530

    authors: Metellus P,Figarella-Branger D,Guyotat J,Barrie M,Giorgi R,Jouvet A,Chinot O,Club de Neuro-Oncologie de la Société Française de Neurochirurgie and the Association des Neuro-Oncologues d'Expression Française.

    更新日期:2008-07-01 00:00:00

  • Effect of secretin and cholecystokinin-pancreozymin on plasma CEA concentration in patients with pancreatic carcinoma and pancreatitis.

    abstract::Plasma CEA concentration before and after administration of secretin and cholecystokinin-pancreozymin has been determined in 89 patients with neoplastic or inflammatory pancreatric disease and other neoplastic and nonneoplastic disorders. The purpose of the study was to expore the specificity and sensitivity of such a...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197906)43:6<2465::aid-cncr282043

    authors: Lindstedt G,Lundberg PA,Rolny P

    更新日期:1979-06-01 00:00:00

  • Typhlitis in childhood cancer.

    abstract:BACKGROUND:Typhlitis is increasingly recognized in children undergoing chemotherapy but is poorly characterized. The authors investigated the demographic, clinical, and imaging (ultrasonography and computed tomography [CT] scans) variables related to the diagnosis, risk, and outcome of typhlitis. METHODS:The authors r...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.21134

    authors: McCarville MB,Adelman CS,Li C,Xiong X,Furman WL,Razzouk BI,Pui CH,Sandlund JT

    更新日期:2005-07-15 00:00:00

  • Epithelioid sarcoma of the vulva. Evidence suggesting a more aggressive behavior than extra-genital epithelioid sarcoma.

    abstract::The authors describe two cases of epithelioid sarcoma of the vulva and summarize the clinical and pathologic experience with this vulvar neoplasm. Findings indicate that epithelioid sarcoma of the vulva usually occurs in the labia majora of young women, but may occur in later life. Clinically it may mimic a Bartholin'...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/1097-0142(19831015)52:8<1462::aid-cncr2820

    authors: Ulbright TM,Brokaw SA,Stehman FB,Roth LM

    更新日期:1983-10-15 00:00:00

  • A phase I trial of 5-fluorouracil, folinic acid, and alpha-2a-interferon in patients with metastatic colorectal carcinoma.

    abstract::The mechanisms of biochemical modulation of 5-fluorouracil (5-FU) cytotoxicity by folinic acid (FA) have been elucidated, and the clinical use of this combination has improved response rates and survival in patients with metastatic colorectal cancer. Recently, Phase II trials also showed potential synergism between al...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/1097-0142(19920215)69:4<889::aid-cncr28206

    authors: Bukowski RM,Inoshita G,Yalavarthi P,Murthy S,Gibson V,Budd GT,Sergi JS,Bauer L,Prestifilippo J

    更新日期:1992-02-15 00:00:00

  • Impact of the posttransplant lymphoproliferative disorder subtype on survival.

    abstract:BACKGROUND:Posttransplant lymphoproliferative disorder (PTLD) is a life-threatening complication of solid organ transplantation. Histologic heterogeneity and a lack of treatment standards have made evaluating clinical outcomes in specific patient populations difficult. This systematic literature review investigated the...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.31339

    authors: Koff JL,Li JX,Zhang X,Switchenko JM,Flowers CR,Waller EK

    更新日期:2018-06-01 00:00:00

  • Treatment of patients with lymphomas of the uterus or cervix with combination chemotherapy and radiation therapy.

    abstract:BACKGROUND:Primary lymphomas of the uterus or cervix are so rare that treatment series of single institutions consist of very small numbers of patients, making standard treatment difficult to define. The outcome of patients treated with a combination of chemotherapy and radiation therapy was analyzed for all but patien...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19950501)75:9<2392::aid-cncr2820

    authors: Stroh EL,Besa PC,Cox JD,Fuller LM,Cabanillas FF

    更新日期:1995-05-01 00:00:00

  • Value of cytologic Papanicolaou smears and polymerase chain reaction screening for human papillomavirus DNA in detecting anal intraepithelial neoplasia: comparison with histology of a surgical sample.

    abstract:BACKGROUND:The performance of cytologic screening and its correlation with histology and polymerase chain reaction (PCR) detection of human papillomavirus (HPV) DNA have not been evaluated in populations with a low prevalence of anal intraepithelial neoplasia (AIN). The objective of the current study was to analyze the...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.27671

    authors: Etienney I,Vuong S,Si-Mohamed A,Fléjou JF,Atienza P,Bauer P,Cytological Diaconesses Group.

    更新日期:2012-12-15 00:00:00

  • Analysis of racial differences in incidence, survival, and mortality for malignant tumors of the uterine corpus.

    abstract:BACKGROUND:In the United States, incidence rates for malignant tumors of the uterine corpus are lower among blacks than among whites, whereas mortality rates are higher among blacks. Reasons for the higher level of mortality among blacks have been debated. METHODS:Using data from the Surveillance, Epidemiology, and En...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.11484

    authors: Sherman ME,Devesa SS

    更新日期:2003-07-01 00:00:00

  • Acral erythema secondary to high-dose cytosine arabinoside with pain worsened by cyclosporine infusions.

    abstract::Acral erythema after high-dose cytosine arabinoside (Ara-C) has been described as a painful, sharply demarcated, and intense erythema of the palms and soles. This phenomenon occurred and is described in three out of three allogeneic bone marrow transplant (BMT) recipients who received high-dose Ara-C and total-body ir...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19890615)63:12<2482::aid-cncr282

    authors: Kampmann KK,Graves T,Rogers SD

    更新日期:1989-06-15 00:00:00

  • Alcohol consumption, finasteride, and prostate cancer risk: results from the Prostate Cancer Prevention Trial.

    abstract:BACKGROUND:Current research is inconclusive regarding the relation between alcohol consumption and prostate cancer risk. In this study, the authors examined the associations of total alcohol, type of alcoholic beverage, and drinking pattern with the risk of total, low-grade, and high-grade prostate cancer. METHODS:Dat...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.24423

    authors: Gong Z,Kristal AR,Schenk JM,Tangen CM,Goodman PJ,Thompson IM

    更新日期:2009-08-15 00:00:00

  • Risk of mortality in patients with cancer who experience febrile neutropenia.

    abstract:BACKGROUND:Febrile neutropenia (FN) is a serious and potentially life-threatening condition that may develop in patients with cancer who receive myelosuppressive chemotherapy. The risk of mortality from FN is not well characterized in current clinical practice. METHODS:Patients with cancer who were receiving chemother...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.25332

    authors: Lyman GH,Michels SL,Reynolds MW,Barron R,Tomic KS,Yu J

    更新日期:2010-12-01 00:00:00

  • Fatal hepatic vascular toxicity of DTIC. Is it really a rare event?

    abstract::A fatal massive hepatic necrosis with widespread thrombotic occlusion of the small hepatic veins developed in two of 68 patients treated with DTIC for advanced melanoma in a randomized study. Thirteen similar reactions, in patients treated with single-agent DTIC, are reported in the literature. Several clinical and pa...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19880515)61:10<1988::aid-cncr282

    authors: Ceci G,Bella M,Melissari M,Gabrielli M,Bocchi P,Cocconi G

    更新日期:1988-05-15 00:00:00

  • Excessive production of nitric oxide in rat solid tumor and its implication in rapid tumor growth.

    abstract:BACKGROUND:Rapid tumor growth is caused by angiogenesis factors, growth factors, etc. We previously reported a possible connection between nitric oxide (NO) and enhanced vascular permeability in solid tumor. In the present experiment, the role of NO in solid tumor pathology was further investigated in animal tumor. ME...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/(SICI)1097-0142(19960415)77:8<1598::AID-CN

    authors: Doi K,Akaike T,Horie H,Noguchi Y,Fujii S,Beppu T,Ogawa M,Maeda H

    更新日期:1996-04-15 00:00:00

  • 111Indium-bleomycin breast and axilla imaging.

    abstract::111Indium-Bleomycin (111In-Blm), a new radiopharmaceutical, was administered intravenously to 37 patients with benign and malignant breast lesions. Early and delayed images of both the breasts and axillae were made, and results were correlated with physical examination, histopathology of the excised lesion, mammograph...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197601)37:1<36::aid-cncr28203701

    authors: Silverstein MJ,Verma RC,Greenfield L,Morton DL

    更新日期:1976-01-01 00:00:00

  • Long-term results of hyperfractionated radiation and high-dose intraarterial cisplatin for unresectable oropharyngeal carcinoma.

    abstract:BACKGROUND:In this report, the authors present the results from a study of patients with unresectable oropharyngeal squamous cell carcinomas who were treated on a protocol of hyperfractionated radiation and high-dose intraarterial cisplatin (HYPERRADPLAT) at the University of Kentucky. METHODS:The study was designed a...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.21368

    authors: Spring PM,Valentino J,Arnold SM,Sloan D,Kenady D,Kudrimoti M,Haydon RC 3rd,Lee C,Given C,Mohiuddin M,Regine WF

    更新日期:2005-10-15 00:00:00

  • Posttherapy pathologic stage predicts survival in patients with esophageal carcinoma receiving preoperative chemoradiation.

    abstract:BACKGROUND:In patients with locoregional carcinoma of the esophagus or esophagogastric junction who underwent preoperative chemoradiation, it is unclear whether survival was better predicted by pretherapy clinical stage or by posttherapy pathologic stage. METHODS:The authors studied 235 consecutive patients with preth...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.20916

    authors: Chirieac LR,Swisher SG,Ajani JA,Komaki RR,Correa AM,Morris JS,Roth JA,Rashid A,Hamilton SR,Wu TT

    更新日期:2005-04-01 00:00:00

  • The identification of patient-specific mutations reveals dual pathway activation in most patients with melanoma and activated receptor tyrosine kinases in BRAF/NRAS wild-type melanomas.

    abstract:BACKGROUND:Increasing knowledge of cancer genomes has triggered the development of specific targeted inhibitors, thus providing a valuable therapeutic pool. METHODS:In this report, the authors analyze the presence of targetable alterations in 136 tumor samples from 92 patients with melanoma using a comprehensive appro...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.31843

    authors: Appenzeller S,Gesierich A,Thiem A,Hufnagel A,Jessen C,Kneitz H,Regensburger M,Schmidt C,Zirkenbach V,Bischler T,Schilling B,Siedel C,Goebeler ME,Houben R,Schrama D,Gehrig A,Rost S,Maurus K,Bargou R,Rosenwald A,Sch

    更新日期:2019-02-15 00:00:00

  • Radiation for bone metastases: conventional techniques and the role of systemic radiopharmaceuticals.

    abstract::Pain management often is difficult in patients with bone metastases. Metastatic disease represents >40% of oncologic practice, and >70% of patients with metastatic disease have uncontrolled cancer-related pain. Significant morbidity caused by pathologic fracture and spinal cord compression can result from untreated bo...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/(sici)1097-0142(19971015)80:8+<1628::aid-c

    authors: Janjan NA

    更新日期:1997-10-15 00:00:00

  • MammoSite excision volume as a predictor for residual disease.

    abstract:BACKGROUND:The MammoSite catheter is a brachytherapy device used for accelerated partial breast irradiation. Currently, it is available as 2 spherically shaped balloons meant to fill 70-cc and 120-cc cavity volumes. This study was designed to define the relation of these excision volumes to the likelihood of microscopi...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.21269

    authors: Kaufman SA,Dipetrillo TA,Ruthazer R,Wazer DE

    更新日期:2005-09-01 00:00:00

  • Notable effects of angiotensin II receptor blocker, valsartan, on acute cardiotoxic changes after standard chemotherapy with cyclophosphamide, doxorubicin, vincristine, and prednisolone.

    abstract:BACKGROUND:There are three distinct types of doxorubicin-induced cardiotoxicity (acute, chronic, and late-onset). Although previous studies with animal models suggest that angiotensin II plays a key role in the process of the doxorubicin-induced cardiotoxicity, there has been no such observation in humans. This randomi...

    journal_title:Cancer

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/cncr.21478

    authors: Nakamae H,Tsumura K,Terada Y,Nakane T,Nakamae M,Ohta K,Yamane T,Hino M

    更新日期:2005-12-01 00:00:00

  • Squamous cell carcinoma of the buccal mucosa associated with chronic oral polyvinyl chloride exposure: report of a case.

    abstract::The following case report describes a 22-year-old healthy man, non-smoker, non-drinker, who developed a squamous cell carcinoma of the buccal mucosa. The appearance of this unusual tumor in an unexpected clinical setting was unexplained until it was discovered that the patient had a lifetime habit of chewing plastic m...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197704)39:4<1686::aid-cncr282039

    authors: Casterline CL,Casterline PF,Jaques DA

    更新日期:1977-04-01 00:00:00

  • The relationship of increasing radiotherapy dose to reduced distant metastases and mortality in men with prostate cancer.

    abstract:BACKGROUND:The association of increasing radiotherapy (RT) dose with reduced biochemical failure (BF) is accepted widely. However, there is little direct evidence that dose escalation has an impact on distant metastasis (DM) or overall mortality (OM). These associations were examined in the current study. METHODS:The ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.11927

    authors: Jacob R,Hanlon AL,Horwitz EM,Movsas B,Uzzo RG,Pollack A

    更新日期:2004-02-01 00:00:00

  • A compound follicular-parafollicular cell carcinoma of the thyroid: a new tumor entity?

    abstract::An unusual thyroid carcinoma is described, showing structural, histochemical and radioimmunologic features of both a follicular and a parafollicular cell carcinoma. Radioimmunoassay revealed high levels of thyroglobulin in the patient's serum and in extracts from metastatic tumor tissue. Immunoreactive thyroglobulin w...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19830915)52:6<1053::aid-cncr2820

    authors: Ljungberg O,Ericsson UB,Bondeson L,Thorell J

    更新日期:1983-09-15 00:00:00

  • Clear cell sarcoma of tendons and aponeuroses in pediatric patients: a report from the Italian and German Soft Tissue Sarcoma Cooperative Group.

    abstract:BACKGROUND:Clear cell sarcoma (CCS) of tendons and aponeuroses is extremely rare in childhood and little information is available on its clinical management. Originally believed to be a type of melanoma of soft tissue origin, CCS is now considered a distinct clinicopathologic entity that behaves like a high-grade soft ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.10597

    authors: Ferrari A,Casanova M,Bisogno G,Mattke A,Meazza C,Gandola L,Sotti G,Cecchetto G,Harms D,Koscielniak E,Treuner J,Carli M

    更新日期:2002-06-15 00:00:00

  • Indolent diffuse histiocytic lymphoma with sclerosis and chylous effusions.

    abstract::A case of diffuse histiocytic lymphoma with sclerosis and chylous pleural and peritoneal effusions spanning four years from onset to diagnosis is presented. Treatment with combination chemotherapy and consolidative radiotherapy resulted in clinical improvement and the patient remains free of disease 14 months after st...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19830601)51:11<2144::aid-cncr282

    authors: Hansen RM,Komaki R,Hanson GA,Schlueter DP,Anderson T

    更新日期:1983-06-01 00:00:00

  • A nonrandom association between gastrointestinal stromal tumors and myeloid leukemia.

    abstract:BACKGROUND:Gastrointestinal stromal tumors (GISTs) are KIT-positive mesenchymal tumors of the gastrointestinal tract that are driven by activated KIT-signalling or platelet-derived growth factor receptor-alpha (PDFGRA) signaling. These tumors most commonly occur in the stomach and small intestine and encompass a clinic...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.23216

    authors: Miettinen M,Kraszewska E,Sobin LH,Lasota J

    更新日期:2008-02-01 00:00:00