Acral erythema secondary to high-dose cytosine arabinoside with pain worsened by cyclosporine infusions.

abstract：BACKGROUND:To the authors' knowledge, there is no standard treatment for patients with T-cell large granular lymphocyte (LGL) leukemia. Available data are limited by patient numbers and coexisting pathologies. METHODS:The authors report on the use of immunosuppressants (cyclosporin A [CSA] and low-dose oral methotrexa...

journal_title：Cancer

authors： Osuji N,Matutes E,Tjonnfjord G,Grech H,Del Giudice I,Wotherspoon A,Swansbury JG,Catovsky D

更新日期：2006-08-01 00:00:00

abstract：:Trastuzumab is a monoclonal antibody used for the treatment of metastatic breast carcinoma in women whose tumors overexpress the HER2 protein. Cardiotoxicity has been reported to occur with trastuzumab when administered alone and in combination with antineoplastic agents, particularly anthracyclines. The risk of cardi...

journal_title：Cancer

authors： Keefe DL

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Sunitinib and sorafenib are small-molecule tyrosine kinase inhibitors (TKI) with antitumor activity in advanced renal cell carcinoma. A retrospective study was conducted to assess the response of renal cell carcinoma to sequential treatment with these two agents. METHODS:Tumor response was evaluated by usin...

journal_title：Cancer

authors： Dudek AZ,Zolnierek J,Dham A,Lindgren BR,Szczylik C

更新日期：2009-01-01 00:00:00

abstract：:A case of endometrial adenoacanthoma is reported in which two histologically distinct populations of cells were identified in the primary tumor. The two cell types differed in that one had phagocytosed large numbers of polymorphonuclear leucocytes. A subsequent skin metastasis was composed entirely of cells capable of...

journal_title：Cancer

authors： Chandrasoma P

更新日期：1980-05-01 00:00:00

abstract：BACKGROUND:Expression of oncofetal fibronectin (oncFN) and normal fibronectin (norFN) in colorectal cancer specimens was examined to investigate the correlation between fibronectin localization and histologic grade, liver metastasis, and prognosis. METHODS:Immunohistochemical staining of oncFN and norFN was performed ...

journal_title：Cancer

authors： Inufusa H,Nakamura M,Adachi T,Nakatani Y,Shindo K,Yasutomi M,Matsuura H

更新日期：1995-06-15 00:00:00

abstract：BACKGROUND:Desmoid tumors are mesenchymal nonmetastasizing neoplasms. Although rare in the general population, they are a common extracolonic manifestation of familial adenomatous polyposis (FAP). Because of high tumor recurrence rates, surgery has been less than satisfactory in the treatment of desmoid tumors. In the ...

journal_title：Cancer

authors： Hansmann A,Adolph C,Vogel T,Unger A,Moeslein G

更新日期：2004-02-01 00:00:00

abstract：:The authors add six patients with focal nodular hyperplasia of the liver to the increasing number reported. All had ingested hormones as contraceptives for periods of from one and one-half to seven years. In five patients, the initial manifestation was massive intraabdominal hemorrhage and hypovolemic shock. Five of t...

journal_title：Cancer

authors： Catalano PW,Early ME,Topolosky HW,Martin EW Jr,Carey LC

更新日期：1977-02-01 00:00:00

abstract：:Forty-nine specimens of carcinoma of the breast were analyzed for estrogen receptor content using the sucrose gradient method and a histochemical method using a conjugate of estradiol (6-BSA-Fluor-CMO-17 beta-estradiol). The specimens analyzed by the histochemical method were graded for fluorescent intensity, percenta...

journal_title：Cancer

authors： Panko WB,Mattioli CA,Wheeler TM

更新日期：1982-05-15 00:00:00

abstract：:An astroblastoma in the cerebrum was investigated with the electron microscope. A distinctive feature of the tumor was the radial arrangement of astrocytic cells around the blood vessels. The blood vessels in the tumor commonly exhibited fenestrated endothelial cells. The endothelium was generally surrounded by lamell...

journal_title：Cancer

authors： Kubota T,Hirano A,Sato K,Yamamoto S

更新日期：1985-02-15 00:00:00

abstract：BACKGROUND:Chronic myeloid leukemia (CML) can be treated effectively with tyrosine kinase inhibitor therapy directed at BCR-ABL, but access to care, medication cost, and adherence may be barriers to treatment. This study was designed to determine whether the insurance status at diagnosis influences CML patient outcomes...

journal_title：Cancer

authors： Perry AM,Brunner AM,Zou T,McGregor KL,Amrein PC,Hobbs GS,Ballen KK,Neuberg DS,Fathi AT

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:We have often encountered difficulties in identifying small liver cancers during surgery. Fluorescent imaging using indocyanine green (ICG) has the potential to detect liver cancers through the visualization of the disordered biliary excretion of ICG in cancer tissues and noncancerous liver tissues compresse...

journal_title：Cancer

authors： Ishizawa T,Fukushima N,Shibahara J,Masuda K,Tamura S,Aoki T,Hasegawa K,Beck Y,Fukayama M,Kokudo N

更新日期：2009-06-01 00:00:00

abstract：:Ewing's sarcoma is a small cell malignant tumor that usually arises in the medullary cavity of bone. Less frequently, it originates in soft tissue and may secondarily invade underlying bone. The origin of Ewing's sarcoma in a periosteal location without extension into either the bone or adjacent soft tissue has not be...

journal_title：Cancer

authors： Bator SM,Bauer TW,Marks KE,Norris DG

更新日期：1986-10-15 00:00:00

abstract：:Screening for the early detection of cancer offers the potential of increasing the number of patients whose cancer is diagnosed in a localized, curable stage. The operation of an efficient and effective early detection program requires that a number of conditions be fulfilled, some of which are difficult to attain. Fi...

journal_title：Cancer

authors： Miller DG

更新日期：1981-03-01 00:00:00

abstract：BACKGROUND:To determine whether high-risk patients with hematuria receive evaluation according to guideline recommendations. METHODS:We recently performed a screening study for bladder cancer using a urine-based tumor marker in 1502 subjects at high risk based on aged > or = 50 years, > or = 10-year smoking history, a...

journal_title：Cancer

authors： Elias K,Svatek RS,Gupta S,Ho R,Lotan Y

更新日期：2010-06-15 00:00:00

abstract：:Scanning electron microscopy was used to examine the appearances of the colonic mucus layer of rats during chemical carcinogenesis with dimethylhydrazine. The normal colonic mucus layer had a dense homogeneous appearance and provided a complete cover for the mucosal epithelium. At high magnifications tiny fenestration...

journal_title：Cancer

authors： Traynor OJ,Costa NL,Wood CB

更新日期：1983-05-15 00:00:00

abstract：:Peanut agglutinin (PNA) receptors were studied in 37 cases of reactive follicular hyperplasia and 66 follicular lymphomas, using the unlabeled peroxidase-antiperoxidase (PAP) method on paraffin embedded material. Based on the binding sites of the lectin, positively stained cells were easily recognized as either cytopl...

journal_title：Cancer

authors： Ree HJ,Hsu SM

更新日期：1983-05-01 00:00:00

abstract：:Metastatic tumors to the mucosa of the stomach are unusual occurrences that can cause clinical and pathologic problems in diagnosis. The authors report 67 cases from the files of the Veterans Administration Center at Houston. Ten cases were found on endoscopic biopsy and 57 at necropsy. Each patient endoscopically eva...

journal_title：Cancer

authors： Green LK

更新日期：1990-04-01 00:00:00

abstract：BACKGROUND:More cases of bronchogenic carcinoma have been reported in recent years, and these patients are more prone to secondary aspergillosis. However, the frequency of secondary aspergillosis in bronchogenic carcinoma still has not been defined clearly in the literature. METHODS:The current study population was co...

journal_title：Cancer

authors： Shahid M,Malik A,Bhargava R

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:A randomized, multicenter trial, double-blind for antiandrogen therapy, compared the antiandrogens bicalutamide and flutamide, each combined with luteinizing hormone-releasing hormone analogue therapy (LHRH-A) in 813 patients with Stage D2 prostate carcinoma. An analysis of time to progression (median follow...

journal_title：Cancer

authors： Schellhammer PF,Sharifi R,Block NL,Soloway MS,Venner PM,Patterson AL,Sarosdy MF,Vogelzang NJ,Chen Y,Kolvenbag GJ

更新日期：1996-11-15 00:00:00

abstract：:As resources become increasingly scarce, oncology professionals and consumers of oncology services are increasingly engaging in advocacy efforts to achieve goals in cancer control. Effective advocacy includes both legislative and direct educational efforts. ...

journal_title：Cancer

authors： Berkman B,Stevenson E,Cravedi KG,Davis A,Lawrence W Jr,Mor V,Ostrander V,Rubenstein LJ,Speers M,Wilson K

更新日期：1991-12-01 00:00:00

abstract：:All patients with a diagnosis of cutaneous malignant melanoma (CMM) in Western Australia from 1980 to 1981 were observed for up to 6 years to determine vital status and to detect the development of local recurrences of the primary lesion. Approximately 35% of all patients had their tumors excised with surgical margins...

journal_title：Cancer

authors： Heenan PJ,English DR,Holman CD,Armstrong BK

更新日期：1992-01-15 00:00:00

abstract：BACKGROUND:The prognostic significance and optimal care of children with differentiated thyroid cancer and pulmonary metastases are not well established. METHODS:Of 209 patients younger than 25 years of age who were treated at University of Texas M. D. Anderson Cancer Center between 1960 and 1990 and for whom there wa...

journal_title：Cancer

authors： Vassilopoulou-Sellin R,Klein MJ,Smith TH,Samaan NA,Frankenthaler RA,Goepfert H,Cangir A,Haynie TP

更新日期：1993-02-15 00:00:00

abstract：BACKGROUND:Hemangiopericytomas and malignant solitary fibrous tumors (HPC/SFT) are rare, closely related sarcomas with unpredictable behavior that respond infrequently to chemotherapy. An optimal systemic treatment strategy for advanced HPC/SFT has not yet been identified. METHODS:We retrospectively analyzed the recor...

journal_title：Cancer

authors： Park MS,Patel SR,Ludwig JA,Trent JC,Conrad CA,Lazar AJ,Wang WL,Boonsirikamchai P,Choi H,Wang X,Benjamin RS,Araujo DM

更新日期：2011-11-01 00:00:00

abstract：:A retrospective study of all cases of seminoma treated at Roswell Park Memorial Institute from 1970 through 1979 was conducted. Fifty-six evaluable patients treated initially with radiation therapy were seen during this period, and the overall survival rate at an average follow-up period of 52 months was 82%. The surv...

journal_title：Cancer

authors： Huben RP,Williams PD,Pontes JE,Panahon AM,Murphy GP

更新日期：1984-04-01 00:00:00

abstract：:One hundred twenty-three women younger than 70 years of age and at clinical Stages I or II were enrolled in a randomized clinical trial of radical versus extended radical mastectomy. The 5-year survival rates in the radical and extended radical groups were 75 +/- 6.7% and 80 +/- 6.7%, respectively. (Cox P value for co...

journal_title：Cancer

authors： Meier P,Ferguson DJ,Karrison T

更新日期：1985-02-15 00:00:00

abstract：:From November 1987 to April 1989, 1000 women 40 years or older underwent screening vaginal sonography at the University of Kentucky Medical Center (Lexington, KY). Patients included in this investigation were all asymptomatic and had no known pelvic abnormalities. Each ovary was measured in three planes and ovarian vo...

journal_title：Cancer

authors： van Nagell JR Jr,Higgins RV,Donaldson ES,Gallion HH,Powell DE,Pavlik EJ,Woods CH,Thompson EA

更新日期：1990-02-01 00:00:00

abstract：BACKGROUND:The demonstration of the monoclonality of immunoglobulin heavy chain (IgH) gene rearrangement is an indispensable method for the diagnosis of B-cell lymphoma as well as histocytochemical analysis. For the detection of IgH gene rearrangement, the extraction of DNA from a homogenous cell population is necessar...

journal_title：Cancer

authors： Orba Y,Tanaka S,Nishihara H,Kawamura N,Itoh T,Shimizu M,Sawa H,Nagashima K

更新日期：2003-08-25 00:00:00

abstract：BACKGROUND:Apricoxib, a novel once-daily selective cyclooxygenase-2 inhibitor, was investigated in combination with erlotinib for recurrent stage IIIB/IV nonsmall cell lung cancer to determine the maximum tolerated dose, dose-limiting toxicity, and recommended phase II dose (RP2D) based on changes in urinary prostaglan...

journal_title：Cancer

authors： Reckamp K,Gitlitz B,Chen LC,Patel R,Milne G,Syto M,Jezior D,Zaknoen S

更新日期：2011-02-15 00:00:00

abstract：:The design of many antineoplastic agents has been based on atom or group replacement in normal metabolites. New dimensions are being added to this approach by the synthesis of transition state, bisubstrate and "suicide" inhibitors. These provide greater potency and in some cases selectivity. Leads for differential sen...

journal_title：Cancer

authors： Handschumacher RE

更新日期：1977-07-01 00:00:00

abstract：BACKGROUND:Soft tissue sarcomas (STSs) are heterogeneous neoplasms that have variable clinical outcome. Several clinical parameters and few molecular markers, including Ki-67 proliferative index, have been shown to correlate with patient prognosis. To the authors' knowledge, no definitive report exists to identify one ...

journal_title：Cancer

authors： Hoos A,Stojadinovic A,Mastorides S,Urist MJ,Polsky D,Di Como CJ,Brennan MF,Cordon-Cardo C

更新日期：2001-08-15 00:00:00