Abstract:
:A case of endometrial adenoacanthoma is reported in which two histologically distinct populations of cells were identified in the primary tumor. The two cell types differed in that one had phagocytosed large numbers of polymorphonuclear leucocytes. A subsequent skin metastasis was composed entirely of cells capable of phagocytosing polymorphs. The ability of cancer cells to phagocytose other cellular elements may provide a histologic marker for the presence of surface membrane abnormalities in these cells. The possibility that this may be associated with metastasis is considered.
journal_name
Cancerjournal_title
Cancerauthors
Chandrasoma Pdoi
10.1002/1097-0142(19800501)45:9<2348::aid-cncr2820subject
Has Abstractpub_date
1980-05-01 00:00:00pages
2348-51issue
9eissn
0008-543Xissn
1097-0142journal_volume
45pub_type
杂志文章相关文献
CANCER文献大全abstract::Grilled or fried meat and fish contain various mutagenic heterocyclic amines, and structures of at least 19 compounds have already been determined. Among these, 10 have been examined for long term carcinogenicity, all proving to be positive. 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), for example, preferen...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19940801)74:3+<1063::aid-cncr282
更新日期:1994-08-01 00:00:00
abstract:BACKGROUND:Monoclonal antibodies have not been evaluated in metastasizing endocrine tumors, even though these lesions may induce severe morbidity of hormone excess in absence of considerable tumor burden. METHODS:A murine monoclonal antibody of the IgG2a subtype was generated by immunization with dispersed tumor cells...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/1097-0142(19940301)73:5<1346::aid-cncr2820
更新日期:1994-03-01 00:00:00
abstract::DNA ploidy and percent of (%S-phase) S-phase cells were determined from the DNA content distribution of 21 benign and 76 malignant (69 primary, 7 metastatic) breast tumors using flow cytometry. All of the benign tumors were diploid, whereas 89% of the malignant tumors had measurable aneuploidy. Multiple stem-lines wer...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19841015)54:8<1586::aid-cncr2820
更新日期:1984-10-15 00:00:00
abstract:BACKGROUND:Radiofrequency (RF)-induced tissue coagulation represents a new approach for the thermal destruction of tumors within the liver. The purpose of the current study was to 1) assess technique safety; 2) determine the extent and evolution of induced cellular damage; and 3) correlate the observed pathologic effec...
journal_title:Cancer
pub_type: 杂志文章
doi:
更新日期:2000-06-01 00:00:00
abstract::Because increased effects have been achieved when murine tumors are irradiated after a period of hypoxia and because of anecdotal clinical experiences of an improved result after irradiation of previously anemic patients in hyperbaric oxygen, the relationship between irradiation and increased survival was investigated...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19890801)64:3<646::aid-cncr28206
更新日期:1989-08-01 00:00:00
abstract::The concentrations of sex hormone binding globulin (SHBG) were measured in the plasma of 56 men, who were 47 to 85 years of age, by time-resolved immunofluorometric assay with a monoclonal antibody. Twenty-five of the men had untreated carcinoma of the prostate and 17 had untreated prostatic hyperplasia. There were 14...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19900715)66:2<354::aid-cncr28206
更新日期:1990-07-15 00:00:00
abstract::Fifty patients with non resectable and/or inoperable bronchogenic carcinoma were entered into a feasibility study of cisplatin (CDDP) given in continuous infusion with concurrent radiation therapy. The radiation therapy regimen consisted of 2 Gy given 5 days a week in the first 3 and last 2 weeks of a 7-week split cou...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19910115)67:2<357::aid-cncr28206
更新日期:1991-01-15 00:00:00
abstract:BACKGROUND:The long-term impact of breast carcinoma and its treatment was assessed in 153 breast carcinoma survivors previously treated on a Phase III randomized trial (Cancer and Leukemia Group B [CALGB 7581]) a median of 20 years after entry to CALGB 7581. METHODS:Survivors were interviewed by telephone using the fo...
journal_title:Cancer
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1002/cncr.11531
更新日期:2003-08-15 00:00:00
abstract::Late side effects of chemotherapy were studied in 51 women who had received at least 300 mg of melphalan for ovarian cancer and had survived for at least three years. Hematologic, statistical, and cytogenetic methods were employed. Six cases of iatrogenic leukemia were found. They appeared to represent a hematologic e...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19820601)49:11<2234::aid-cncr282
更新日期:1982-06-01 00:00:00
abstract:BACKGROUND:The authors hypothesized that insurance payer and race would influence the care and outcomes for patients with breast carcinoma. METHODS:The authors examined treatments and adjusted risk of death (through 1997) for all incident cases of breast carcinoma occurring in Florida in 1994 (n = 11,113) by using sta...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(20001201)89:11<2202::aid-cncr8>3
更新日期:2000-12-01 00:00:00
abstract:BACKGROUND:Interleukin-2 (IL-2) is used in the treatment of solid tumors and hematologic malignancies. Sudden death is a rare complication of IL-2 treatment. METHODS:A patient with lymphoma underwent chemoradiotherapy myeloablation and autologous stem cell transplantation. The stem cells were cultured in IL-2 (6000 IU...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(sici)1097-0142(19980915)83:6<1231::aid-cn
更新日期:1998-09-15 00:00:00
abstract:BACKGROUND:Overall survival (OS) is considered the gold standard for determining treatment efficacy in oncology trials, but the relation between treatment and OS can be challenging to assess because of long study durations and the impact of subsequent therapies on outcome. Using OS can be particularly difficult for new...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.30622
更新日期:2017-05-15 00:00:00
abstract:BACKGROUND:Oral mucositis (OM) is a frequent complication of mucotoxic cancer therapy, causing significant oral pain, increased infection risk, and impaired functioning. The efficacy and safety of Saforis (glutamine) powder in UpTec for oral suspension was evaluated for the prevention and treatment of OM. METHODS:Thre...
journal_title:Cancer
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/cncr.22384
更新日期:2007-01-15 00:00:00
abstract::A parotid tumor having sebaceous differentiation and a particular histologic picture previously undescribed is reported. The tumor showed features of an adenolymphoma but almost completely lacked a lymphoid component. Sebaceous differentiation was seen in the epithelium of many cysts. Additionally, groups of oxyphilic...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197904)43:4<1429::aid-cncr282043
更新日期:1979-04-01 00:00:00
abstract::Histologic groups in 231 cases of malignant lymphoma were correlated with survival data at 100 months from the time of initiation of the study. Patients in the first two decades of life fared comparably with adults, but those over 60 years of age showed a poorer survival trend. Seven favorable and four unfavorable his...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19810615)47:12<2894::aid-cncr282
更新日期:1981-06-15 00:00:00
abstract::A 69-year-old man with metastatic islet cell carcinoma was treated with streptozotocin and achieved excellent tumor regression. Sixty-seven grams of streptozotocin were given over 28 months. After completion of streptozotocin therapy, the patient had progressive leukopenia. Thirteen months after discontinuation of str...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19810415)47:8<1963::aid-cncr2820
更新日期:1981-04-15 00:00:00
abstract:BACKGROUND:A National Institutes of Health (NIH) Consensus Development Conference on the treatment of patients with early stage invasive breast carcinoma, held in June 1990, recommended breast conservation therapy for the majority of women with Stage I or II breast carcinoma. The authors evaluated the national use of b...
journal_title:Cancer
pub_type: 杂志文章
doi:
更新日期:1999-08-15 00:00:00
abstract:BACKGROUND:Breast cancer advocacy movements, driven by advocate-led civil society organizations (CSOs), have proven to be a powerful force for the advancement of cancer control in high-income countries (HICs). However, although patient advocacy movements are growing in low-income and middle-income countries (LMICs) in ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.32852
更新日期:2020-05-15 00:00:00
abstract::Until recently the prognosis of childhood non-Hodgkin's lymphoma has been poor. A program of combination chemotherapy and involved area radiotherapy was instituted in the Department of Pediatrics at Roswell Park Memorial Institute in 1971. Thirty-one biopsy proven untreated children entered this study. There were 4 St...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197805)41:5<1997::aid-cncr282041
更新日期:1978-05-01 00:00:00
abstract:BACKGROUND:In the past 4 years, the weekly 24-hour infusion of high dose 5-fluorouracil (5-FU) and leucovorin in the treatment of patients with advanced gastric carcinoma has been prospectively studied at the authors' institution. This has enabled them to explore the possibility that the level of expression of thymidyl...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/(sici)1097-0142(19980501)82:9<1626::aid-cn
更新日期:1998-05-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to analyze the extent of hypoxia in prostate carcinoma tumors using the Eppendorf pO(2) microelectrode and correlate this with pretreatment characteristics and prognostic factors. METHODS:Custom-made Eppendorf pO(2) microelectrodes were used to obtain pO(2) measurements from th...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(20001101)89:9<2018::aid-cncr19>3
更新日期:2000-11-01 00:00:00
abstract:BACKGROUND:: Although platinum-based combinations are considered the best option of care for patients with advanced nonsmall cell lung cancer (NSCLC), single-agent therapy is the preferred treatment for older patients. Since the late 1990s, various combinations of third-generation agents (gemcitabine [G], vinorelbine, ...
journal_title:Cancer
pub_type: 杂志文章,meta分析
doi:10.1002/cncr.24207
更新日期:2009-05-01 00:00:00
abstract:BACKGROUND:Soft tissue sarcomas of the head and neck represent uncommon malignant neoplasms. With the exception of orbital and parameningeal sites, the treatment of sarcomas in the head and neck has not been standardized. The authors used a prospectively collected database of adult soft tissue sarcomas to identify prog...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19940715)74:2<697::aid-cncr28207
更新日期:1994-07-15 00:00:00
abstract:BACKGROUND:High mobility group AT-hook 1 (HMGA1) proteins are architectural transcription factors that are overexpressed by pancreatic adenocarcinomas. The authors hypothesized that tumor HMGA1 status represents a novel prognostic marker in pancreatic adenocarcinoma. They also tested the hypothesis that HMGA1 promotes ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.23560
更新日期:2008-07-15 00:00:00
abstract:BACKGROUND:This Phase III trial was performed to compare the roles of oral etoposide and intravenous (i.v.) vinblastine in the treatment of Mediterranean Kaposi's Sarcoma (MEKS) in elderly patients with severe disease (Stages II, Ac/B, III, and IV). PATIENTS AND METHODS:Sixty-five patients were randomized to receive e...
journal_title:Cancer
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/1097-0142(19941115)74:10<2873::aid-cncr282
更新日期:1994-11-15 00:00:00
abstract:BACKGROUND:Previous studies have suggested an excess cancer risk in patients with carcinoid tumors. This association was reexamined using truly population-based data. METHODS:By means of data from the Danish Cancer Registry all carcinoid tumors diagnosed in Denmark between 1978 and 1989 were identified. All patients w...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19950701)76:1<106::aid-cncr28207
更新日期:1995-07-01 00:00:00
abstract::We assessed the frequency of silent (i.e., clinically asymptomatic) cirrhosis among 305 patients with hepatocellular carcinoma (HCC) and cirrhosis in relation to the patients' country of birth, the cause of the cirrhosis, clinical features, and hepatitis B surface antigen (HBsAg) status. Overall, 56% of the patients h...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19900401)65:7<1607::aid-cncr2820
更新日期:1990-04-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to determine the independent prognostic variables in a well documented subset of 216 patients with localized primary malignant fibrous histiocytomas (MFH). METHODS:Between the years 1980 and 1989, 216 patients with localized, primary (International Union Against Cancer [UICC]/A...
journal_title:Cancer
pub_type: 杂志文章,多中心研究
doi:10.1002/(SICI)1097-0142(19960501)77:9<1823::AID-CN
更新日期:1996-05-01 00:00:00
abstract:BACKGROUND:A high prevalence of thrombocytosis in malignant mesothelioma has been reported, although its pathogenesis remains unknown. METHODS:The case of a patient with marked thrombocytosis in peritoneal malignant mesothelioma is reported. To investigate the cytokines responsible for thrombocytosis in this patient, ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19921015)70:8<2105::aid-cncr2820
更新日期:1992-10-15 00:00:00
abstract:BACKGROUND:The usefulness of fine-needle aspiration biopsy (FNAB) for the histologic subtyping of specific sarcomas still is somewhat controversial but is becoming increasingly popular in the U.S. METHODS:To determine the accuracy and usefulness of FNAB in the differential diagnosis of myxoid sarcoma, the authors retr...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(20000625)90:3<167::aid-cncr5>3.0
更新日期:2000-06-25 00:00:00