Sequential therapy with sorafenib and sunitinib in renal cell carcinoma.

abstract：:Although progress has been made in providing cancer prevention and control services to the population, there remain sizeable segments of the population that are either uninvolved or underinvolved with national and state efforts. One method of reaching most of the population, including those segments currently not invo...

journal_title：Cancer

authors： Iverson DC

更新日期：1993-08-01 00:00:00

abstract：:The report describes a clinical trial on conservative surgery in progress at the National Cancer Institute of Milan, Italy. The randomized clinical trial compares radical mastectomy with a more conservative procedure consisting of mammary resection plus axillary dissection plus radiotherapy. The resection comprises an...

journal_title：Cancer

authors： Veronesi U,Banfi A,Saccozzi R,Salvadori B,Zucali R,Uslenghi C,Greco M,Luini A,Rilke F,Sultan L

更新日期：1977-06-01 00:00:00

abstract：:Adrenal cortical carcinoma is an uncommon neoplasm in children. Only a handful of congenital adrenal cortical carcinoma cases have been described. A newborn who had metastatic adrenal cortical carcinoma (skin metastases and cerebral lesions) is described. This patient underwent surgical resection of the right adrenal ...

journal_title：Cancer

authors： Saracco S,Abramowsky C,Taylor S,Silverman RA,Berman BW

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND:Recent scientific advances provide the opportunity to identify women in the general population at increased breast cancer risk and to offer effective early detection and disease prevention interventions. METHODS:A pedigree assessment tool (PAT) was designed to identify women in primary care settings who are...

journal_title：Cancer

authors： Hoskins KF,Zwaagstra A,Ranz M

更新日期：2006-10-15 00:00:00

abstract：BACKGROUND:The AKT inhibitor MK-2206 at a dose of 60 mg every other day was evaluated in gastric/gastroesophageal junction cancers. METHODS:Patients who had progressed after first-line treatment were eligible. Pertinent eligibility criteria included adequate organ function, a fasting serum glucose level ≤ 150 mg/dL, a...

journal_title：Cancer

authors： Ramanathan RK,McDonough SL,Kennecke HF,Iqbal S,Baranda JC,Seery TE,Lim HJ,Hezel AF,Vaccaro GM,Blanke CD

更新日期：2015-07-01 00:00:00

abstract：:Sixteen patients with metastatic neuroendocrine tumors and the malignant carcinoid syndrome were treated with cyproheptadine (Periactin, Merck, Sharp & Dohme, West Point, PA) at maximum tolerable doses that ranged from 12 to 48 mg daily. Usual side effects were mild sedation and dry mouth, but three patients found it ...

journal_title：Cancer

authors： Moertel CG,Kvols LK,Rubin J

更新日期：1991-01-01 00:00:00

abstract：:A retrospective study of all cases of seminoma treated at Roswell Park Memorial Institute from 1970 through 1979 was conducted. Fifty-six evaluable patients treated initially with radiation therapy were seen during this period, and the overall survival rate at an average follow-up period of 52 months was 82%. The surv...

journal_title：Cancer

authors： Huben RP,Williams PD,Pontes JE,Panahon AM,Murphy GP

更新日期：1984-04-01 00:00:00

abstract：BACKGROUND:Preclinical and clinical studies suggest synergistic activity between somatostatin analogues and mammalian target of rapamycin inhibitors. The activity and safety of everolimus was assessed in combination with octreotide long-acting repeatable (LAR) in patients with neuroendocrine tumors (NETs) of gastroente...

journal_title：Cancer

authors： Bajetta E,Catena L,Fazio N,Pusceddu S,Biondani P,Blanco G,Ricci S,Aieta M,Pucci F,Valente M,Bianco N,Mauri CM,Spada F

更新日期：2014-08-15 00:00:00

abstract：BACKGROUND:Few previous articles have analyzed the relation between infection with Helicobacter pylori (H. pylori) and primary gastric lymphoma in a large number of patients. METHODS:Resected and biopsied specimens from 237 patients with primary gastric lymphoma were investigated for H. pylori using hematoxylin and eo...

journal_title：Cancer

authors： Nakamura S,Yao T,Aoyagi K,Iida M,Fujishima M,Tsuneyoshi M

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:At the time of diagnosis of colorectal carcinoma, 2-3% of patients are likely to be harboring brain metastases, and another 10% of patients will develop brain lesions during the course of their disease. The purpose of this study was to examine the clinical course of a group of patients with metastatic brain ...

journal_title：Cancer

authors： Wroński M,Arbit E

更新日期：1999-04-15 00:00:00

abstract：:There were no significant differences between the mean blood plasma (leukocyte-free) RNAase activity among 128 healthy women volunteers age 13-70 and 49 women with benign gynecological tumors. Exceptions to this finding were three apparently healthy women volunteers who had plasma enzyme activity which was higher than...

journal_title：Cancer

authors： Sheid B,Lu T,Pedrinan L,Nelson JH Jr

更新日期：1977-05-01 00:00:00

abstract：BACKGROUND:Despite significant advances in understanding the biology of renal cell carcinoma (RCC) during the past decade, metastatic disease remains nearly incurable and a major medical challenge. Because RCC is known to be immunogenic, immunotherapeutic agents such as recombinant human interleukin-2 (rIL-2) and inter...

journal_title：Cancer

authors： Bukowski RM

更新日期：1997-10-01 00:00:00

abstract：:This paper presents an overview of factors, attitudes, and beliefs that may influence the adoption of cancer prevention and detection strategies by health-care providers and the public. Health-care practitioners require education about prevention and detection approaches to health care and the social variations in the...

journal_title：Cancer

authors： Fink DJ,Sheehan HE

更新日期：1988-06-01 00:00:00

abstract：BACKGROUND:In the past 4 years, the weekly 24-hour infusion of high dose 5-fluorouracil (5-FU) and leucovorin in the treatment of patients with advanced gastric carcinoma has been prospectively studied at the authors' institution. This has enabled them to explore the possibility that the level of expression of thymidyl...

journal_title：Cancer

authors： Yeh KH,Shun CT,Chen CL,Lin JT,Lee WJ,Lee PH,Chen YC,Cheng AL

更新日期：1998-05-01 00:00:00

abstract：:A prospective study of four cycles of etoposide with ifosfamide and cisplatin (VIP) chemotherapy was conducted in 42 germ cell tumor (GCT) patients who were refractory to cisplatin with etoposide/vinblastine-based therapy. Forty patients were evaluable for response. Ten patients (25%) had a complete response: seven to...

journal_title：Cancer

authors： Motzer RJ,Cooper K,Geller NL,Bajorin DF,Dmitrovsky E,Herr H,Morse M,Fair W,Sogani P,Russo P

更新日期：1990-12-15 00:00:00

abstract：BACKGROUND:Aprotinin has been used to decrease blood loss with complicated cardiac surgery but has not been investigated in extrapleural pneumonectomy, an operation that does not use cardiopulmonary bypass. In this prospective, randomized, placebo-controlled, double-blind trial, the authors investigated whether aprotin...

journal_title：Cancer

authors： Norman PH,Thall PF,Purugganan RV,Riedel BJ,Thakar DR,Rice DC,Huynh L,Qiao W,Wen S,Smythe WR

更新日期：2009-02-15 00:00:00

abstract：:A case of a hemangiopericytoma tumor metastatic to the lung from a central nervous system primary tumor in the posterior fossa is reported. The tumor was not responsive to treatment with cyclophosphamide, Adriamycin (doxorubicin), vincristine, DTIC (CYVADIC), high-dose methotrexate with citrovorum factor rescue, aziri...

journal_title：Cancer

authors： Hart LL,Weinberg JB

更新日期：1987-08-15 00:00:00

abstract：:The unique characteristics of tumor vasculature represent an attractive target that may be exploited by vascular-targeting anticancer agents. A promising strategy involves the selective disruption of established tumor blood vessels by tumor-vascular disrupting agents (tumor-VDAs), which exhibit antivascular activity, ...

journal_title：Cancer

authors： McKeage MJ,Baguley BC

更新日期：2010-04-15 00:00:00

abstract：BACKGROUND:Tropisetron (ICS 205-930) antagonizes the serotonin type 3 receptor and has antiemetic activity in animals given cisplatin. Its mean serum half-life in 11.1 hours. METHODS:In this dose-ranging trial, 22 patients undergoing anti-cancer chemotherapy received 24 courses of a single intravenous infusion of trop...

journal_title：Cancer

authors： Pisters KM,Kris MG,Tyson LB,Clark RA,Gralla RJ

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Louisiana is one of the few Southern states that enacted the Medicaid expansion of the Patient Protection and Affordable Care Act (ACA). To the authors' knowledge, the issue of how this has affected the breast cancer landscape in Louisiana is unknown. The authors have postulated that ACA expansion had a posi...

journal_title：Cancer

authors： Chu QD,Li T,Hsieh MC,Yi Y,Gibbs JF,Lyons JM 3rd,Wu XC

更新日期：2020-11-03 00:00:00

abstract：BACKGROUND:Because the prostatic capsule is often indistinct, recognition of extraprostatic extension by carcinoma depends heavily on the identification of carcinoma cells in the periprostatic adipose tissue. However, the distribution of adipose tissue along the prostatic surfaces has not been studied extensively. MET...

journal_title：Cancer

authors： Hong H,Koch MO,Foster RS,Bihrle R,Gardner TA,Fyffe J,Ulbright TM,Eble JN,Cheng L

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:The current study was conducted to evaluate severe mucocutaneous toxicity during treatment with hydroxyurea (HU) in a large cohort of patients with Philadelphia chromosome-negative myeloproliferative neoplasms (MPN). METHODS:Among 993 consecutive patients newly diagnosed with MPN at 4 centers in Rome betwee...

journal_title：Cancer

authors： Latagliata R,Spadea A,Cedrone M,Di Giandomenico J,De Muro M,Villivà N,Breccia M,Anaclerico B,Porrini R,Spirito F,Rago A,Avvisati G,Alimena G,Montanaro M,Andriani A,Gruppo Laziale SMPC Ph1 neg.

更新日期：2012-01-15 00:00:00

abstract：BACKGROUND:Disseminated intravascular coagulation (DIC) and primary fibrinolysis have both been reported in association with prostate carcinoma. The correct diagnosis of the coagulopathy can be difficult and the appropriate management controversial. METHODS:A case is presented of a man in whom DIC and soft tissue hemo...

journal_title：Cancer

authors： Cooper DL,Sandler AB,Wilson LD,Duffy TP

更新日期：1992-08-01 00:00:00

abstract：:Serum sialyltransferases and fucosyltransferases measured by an affinity adsorbent technique were studied in 27 exactly defined patients with malignant pulmonary diseases. Fourteen patients with benign pulmonary diseases and 56 with benign surgical diseases were used as controls. Enzyme activities were expressed as am...

journal_title：Cancer

authors： Ronquist G,Nou E

更新日期：1983-11-01 00:00:00

abstract：:Androgen receptors (AR) and estrogen receptors (ER) were consecutively assayed for hepatocellular carcinoma (HCC) and the surrounding liver was removed surgically from 19 female patients. Patient age ranged from 43 to 79 years, with an average of 61 +/- 9 years. All patients had underlying liver disease (liver cirrhos...

journal_title：Cancer

authors： Nagasue N,Kohno H,Chang YC,Hayashi T,Utsumi Y,Nakamura T,Yukaya H

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Adenocarcinomas of the appendix represent a heterogeneous disease depending on the presence of mucinous histology, histologic grade, and stage. In the current study, the authors sought to explore the interplay of these factors with systemic chemotherapy in a large population data set. METHODS:Patients in th...

journal_title：Cancer

authors： Asare EA,Compton CC,Hanna NN,Kosinski LA,Washington MK,Kakar S,Weiser MR,Overman MJ

更新日期：2016-01-15 00:00:00

abstract：:The authors add six patients with focal nodular hyperplasia of the liver to the increasing number reported. All had ingested hormones as contraceptives for periods of from one and one-half to seven years. In five patients, the initial manifestation was massive intraabdominal hemorrhage and hypovolemic shock. Five of t...

journal_title：Cancer

authors： Catalano PW,Early ME,Topolosky HW,Martin EW Jr,Carey LC

更新日期：1977-02-01 00:00:00

abstract：BACKGROUND:To identify the factors that contribute to poorer colon carcinoma survival rates for African Americans compared with Caucasians, the authors evaluated survival differences based on the histologic grade (differentiation) of the tumor. METHODS:All 169 African Americans and 229 randomly selected non-Hispanic C...

journal_title：Cancer

authors： Alexander D,Jhala N,Chatla C,Steinhauer J,Funkhouser E,Coffey CS,Grizzle WE,Manne U

更新日期：2005-05-15 00:00:00

abstract：:Six patients with Hodgkin's disease who developed idiopathic thrombocytopenic purpura (ITP) are presented. In contrast to prior cases reported in the literature, none of these patients developed recurrent Hodgkin's disease at the time of or subsequent to their thrombocytopenia, with follow-up data available up to 10 y...

journal_title：Cancer

authors： Cohen JR

更新日期：1978-02-01 00:00:00

abstract：BACKGROUND:To describe continuing care and rehabilitation needs of cancer patients, a longitudinal design (6 months) was performed among patients 50 years of age and older with solid tumors. The study examined how age, type of treatment, site of cancer, and symptom experience affect physical functioning and their menta...

journal_title：Cancer

authors： Given CW,Given BA,Stommel M

更新日期：1994-10-01 00:00:00