Abstract:
:A case of a hemangiopericytoma tumor metastatic to the lung from a central nervous system primary tumor in the posterior fossa is reported. The tumor was not responsive to treatment with cyclophosphamide, Adriamycin (doxorubicin), vincristine, DTIC (CYVADIC), high-dose methotrexate with citrovorum factor rescue, aziridinobenzoquinone (AZQ), or dibromodulcitol. However, the patient has had a prolonged survival, lasting for more than 26 years from original diagnosis, despite extensive recurrent primary disease and massive pulmonary metastases. Clinical and pathologic characteristics of these tumors are reviewed, with emphasis on the potential for long-term survival.
journal_name
Cancerjournal_title
Cancerauthors
Hart LL,Weinberg JBdoi
10.1002/1097-0142(19870815)60:4<916::aid-cncr28206subject
Has Abstractpub_date
1987-08-15 00:00:00pages
916-20issue
4eissn
0008-543Xissn
1097-0142journal_volume
60pub_type
杂志文章相关文献
CANCER文献大全abstract:BACKGROUND:Investigations regarding the impact of tumor biology after surgical management of colorectal liver metastasis have focused largely on overall survival. We investigated the impact of codon-specific KRAS mutations on the rates and patterns of recurrence in patients after surgery for colorectal liver metastasis...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.30085
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:Microwave ablation has recently been developed as a safe and effective treatment for a variety of tumors. The authors evaluated the safety and efficacy of computed tomography (CT)-guided percutaneous microwave ablation of adrenal malignant tumors. METHODS:Nine patients between 41 and 83 years of age (averag...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.26128
更新日期:2011-11-15 00:00:00
abstract:BACKGROUND:Six human pancreatic carcinoma cell lines, designated as KMP-1 to KMP-6, were established and maintained in vitro for > 3 years. All were derived from pancreatic ductal adenocarcinomas. The six cell lines originated from either primary pancreatic tumors, metastatic liver tumors, or metastases to lymph nodes....
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(sici)1097-0142(19990215)85:4<832::aid-cnc
更新日期:1999-02-15 00:00:00
abstract:BACKGROUND:Deletion or loss of heterozygosity (LOH) at the polymorphic loci on the short arm of chromosome 3 has been reported in a large number of renal cell, small cell lung, non-small cell lung, and cervical carcinomas, suggesting the presence of one or more putative tumor suppressor genes at chromosome 3p. Similar ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19930801)72:3<881::aid-cncr28207
更新日期:1993-08-01 00:00:00
abstract::Sixty-four adult patients with refractory acute lymphocytic leukemia (ALL) received salvage therapy with the vincristine, doxorubicin (Adriamycin, Adria Laboratories, Columbus, OH), and dexamethasone (VAD) regimen consisting of induction chemotherapy with the three agents followed by multiple-agent maintenance therapy...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19890701)64:1<16::aid-cncr282064
更新日期:1989-07-01 00:00:00
abstract::Between September 21, 1973 and May 9, 1975, 36 patients with metastatic cervical adenopathy from cancers primarily arising in the pharynx or oral cavity, including six with bilateral cervical involvement, received fast neutron teletherapy at the University of Washington. At the conclusion of treatment, the masses were...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197606)37:6<2613::aid-cncr282037
更新日期:1976-06-01 00:00:00
abstract::Thrombocytopenia in patients with multiple myeloma is usually due to chemotherapy or marrow replacement with myeloma cells. Two patients with multiple myeloma who fulfilled criteria for the diagnosis of immune thrombocytopenic purpura are presented. The etiologic and therapeutic implications of this unusual associatio...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19850901)56:5<1199::aid-cncr2820
更新日期:1985-09-01 00:00:00
abstract::Epidemiologic variables related to breast cancer risk were assessed in a case-control study of 332 women with breast carcinoma and 1353 comparison women. Risk factors for breast cancer as a whole included nulliparity, late age at first childbirth, early age at menarche, late age at menopause, personal history of benig...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19820501)49:9<1937::aid-cncr2820
更新日期:1982-05-01 00:00:00
abstract::Improvement in the management of acute leukemia in adults has not progressed nearly so rapidly as has the treatment of childhood leukemia. One important difference is that most adults have myeloblastic or related forms of the disease (AML), whereas the majority of children have lymphoblastic leukemia (ALL). However, e...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197508)36:2+<775::aid-cncr282036
更新日期:1975-08-01 00:00:00
abstract::Non-Hodgkin's lymphoma confined to the liver is unusual in adults and has not been reported in children. Two children with primary hepatic and one with hepatosplenic NHL are described. All three patients are males, and both tumors examined for cell surface markers were of B-cell origin. Two patients, treated with chem...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19831215)52:12<2285::aid-cncr282
更新日期:1983-12-15 00:00:00
abstract:BACKGROUND:The authors investigated the prevalence of pretreatment urinary, sexual, hormonal, and bowel dysfunction in a contemporary, population-based prostate cancer cohort. They also explored the associations between baseline function and age, comorbidity, and timing of baseline survey completion with respect to tre...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.28563
更新日期:2014-04-15 00:00:00
abstract:BACKGROUND:Since the introduction of the TNM residual tumor (R) classification, the involvement of resection margins has been defined either as a microscopic (R1) or a macroscopic (R2) demonstration of tumor directly at the resection margin ("tumor transected"). METHODS:The recognition of the importance of the circumf...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.24320
更新日期:2009-08-01 00:00:00
abstract:BACKGROUND:Ewing's sarcomas, osteosarcomas, and rhabdomyosarcomas are significantly more responsive to chemotherapy than other sarcomas. Adjuvant chemotherapy is used routinely based on data from randomized trials. Although a percentage of children with locally advanced or metastatic tumors remain curable, few data exi...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:
更新日期:1998-04-01 00:00:00
abstract:BACKGROUND:Apricoxib, a novel once-daily selective cyclooxygenase-2 inhibitor, was investigated in combination with erlotinib for recurrent stage IIIB/IV nonsmall cell lung cancer to determine the maximum tolerated dose, dose-limiting toxicity, and recommended phase II dose (RP2D) based on changes in urinary prostaglan...
journal_title:Cancer
pub_type: 杂志文章,多中心研究
doi:10.1002/cncr.25473
更新日期:2011-02-15 00:00:00
abstract::Major advances have been made in melanoma treatment with the use of molecularly targeted therapies and immunotherapies, and numerous regimens are now approved by the US Food and Drug Administration for patients with stage IV disease. However, therapeutic resistance remains an issue to both classes of agents, and relia...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/cncr.30681
更新日期:2017-06-01 00:00:00
abstract::The ultrastructure of three cases of osteoblastoma is described. The osteoblasts resemble normal osteoblasts with a few exceptions: irregular, indented nuclei, and occasional mitochondria with curved cristae and electron-lucent areas. The osteocytes and osteoclasts basically resemble their normal counterparts. There a...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197705)39:5<2127::aid-cncr282039
更新日期:1977-05-01 00:00:00
abstract:BACKGROUND:This survey documents the strategies used by pain control physicians in the selection of opioid drugs and routes of administration in the management of inpatients referred to a cancer pain service. METHODS:The following approaches were prospectively evaluated during the treatment of 100 consecutive inpatien...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19951001)76:7<1283::aid-cncr2820
更新日期:1995-10-01 00:00:00
abstract:BACKGROUND:DNA flow cytometry of hepatocellular carcinoma (HCC) cells has been investigated in many studies, but, to the best of our knowledge, there are no data on DNA analysis of cirrhotic parenchyma around the HCC. In this study, cell kinetics and ploidy of parenchymal cells around HCC were performed to ascertain if...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0142(19960915)78:6<1195::AID-CN
更新日期:1996-09-15 00:00:00
abstract::The lymphocytotoxic effect of therapeutic irradiation may lead to immune depression. The significance of such effects is yet to be determined in many malignancies, especially in light of the persistant immune depression in many "cured" patients. The present review examines the effects of age, type of cancer, and stage...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197702)39:2+<737::aid-cncr282039
更新日期:1977-02-01 00:00:00
abstract::Results of cytogenetic studies of a patient with acute granulocytic leukemia are described. The modal number of chromosomes in cells from bone marrow samples was 43; the karyotype was characterized by missing chromosomes in groups B, C, and E. According to successive studies of the same metaphases by fluorescent stain...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197502)35:2<378::aid-cncr2820350
更新日期:1975-02-01 00:00:00
abstract:BACKGROUND:Prognostic implications of overexpression of the HER-2 gene in nonsmall cell lung carcinoma (NSCLC) are a matter of controversy. Many conflicting results have been reported from different laboratories. METHODS:A metaanalysis of published studies was performed for this quantitative review of the effects of H...
journal_title:Cancer
pub_type: 杂志文章,meta分析
doi:10.1002/cncr.20957
更新日期:2005-05-01 00:00:00
abstract:BACKGROUND:Oral tongue cancer incidence has increased among whites in the United States; however, the cause remains unknown. If an infectious agent is implicated, then elevated risk would be expected among immunosuppressed individuals. METHODS:By using population-based registry linkage information from the US Transpla...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.31359
更新日期:2018-06-15 00:00:00
abstract::The expression of the Thomsen-Friedenreich antigen (T-antigen) in normal and neoplastic urothelium was investigated using paraffin-processed and fresh frozen tissue sections obtained by biopsy from 56 patients. The T-antigen was detected through its binding to the peanut agglutinin (PNA) with two methods: a biotin-avi...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19860915)58:6<1236::aid-cncr2820
更新日期:1986-09-15 00:00:00
abstract:BACKGROUND:Assessment of the responses of osteosarcoma patients to preoperative chemotherapy is of clinical importance. The purpose of this study was to estimate the accuracy of angiography and thallium-201 scintigraphy, compared with histology, in assessing the responses of patients with osteosarcoma to preoperative c...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(sici)1097-0142(19990915)86:6<949::aid-cnc
更新日期:1999-09-15 00:00:00
abstract:BACKGROUND:Some patients with chronic myeloid leukemia (CML) have a history of previous malignancies. To the authors' knowledge, outcomes for CML diagnosed in these patients have not been well described. The current study was conducted to determine the outcome of patients with CML and a history of prior malignancies. ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.30362
更新日期:2017-02-15 00:00:00
abstract::To assess whether chemosensitivity in metastatic soft tissue sarcoma (STS) is influenced by the histologic grade of the tumor, the authors retrospectively analyzed tumor responses to doxorubicin-based chemotherapy in four prospective studies conducted at the Mayo Clinic, Rochester, Minnesota, between 1976 and 1984. A ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19911201)68:11<2354::aid-cncr282
更新日期:1991-12-01 00:00:00
abstract::Transthoracic fine needle aspiration (FNA) biopsies performed under computed tomography (CT) scan (CT-FNA) have greatly improved the cytodiagnosis of lung tumors. However, the distinction between a primary lesion and a metastatic lesion still may be difficult on the basis of morphologic criteria. To evaluate whether a...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19891215)64:12<2493::aid-cncr282
更新日期:1989-12-15 00:00:00
abstract:BACKGROUND:Transforming growth factor beta (TGFbeta) is important in colorectal cancer (CRC) progression. Bone morphogenetic proteins (BMPs), a subgroup within the TGFbeta superfamily, recently also have been implicated in CRC, but their precise role in CRC has yet to be investigated. METHODS:The authors used a tissue...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.23160
更新日期:2008-01-15 00:00:00
abstract::African American men experience worse prostate cancer outcomes compared with those of Caucasian men, not only in incidence and mortality rates, but also in coping with the side effects of treatment. Unfortunately, African American men have been significantly under-represented in research evaluating the efficacy of psy...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.22355
更新日期:2007-01-15 00:00:00
abstract:BACKGROUND:Obesity is a well known risk factor for the development of endometrial cancer; however, weight alone does not account for all cases. The authors hypothesized that insulin resistance also contributes to an increased risk for endometrial cancer. Adiponectin is a protein secreted by adipose cells and has been s...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.21866
更新日期:2006-06-01 00:00:00