Does histologic grade in soft tissue sarcoma influence response rate to systemic chemotherapy?

abstract：BACKGROUND:Fine-needle aspiration biopsy (FNA) has been successful in diagnosing epithelial lesions of the breast. Its role in the evaluation of spindle cell and mesenchymal lesions of the breast, which include a variety of benign and malignant conditions, is less clear. This article discusses the cytologic features an...

journal_title：Cancer

authors： Chhieng DC,Cangiarella JF,Waisman J,Fernandez G,Cohen JM

更新日期：1999-12-25 00:00:00

abstract：BACKGROUND:The objective of this study was to assess the racial and ethnic disparities in outcomes and their association with process-of-care measures for elderly Medicare recipients with localized prostate cancer. METHODS:The Surveillance, Epidemiology, and End Results-Medicare databases for the period from 1995 to 2...

journal_title：Cancer

authors： Jayadevappa R,Chhatre S,Johnson JC,Malkowicz SB

更新日期：2011-06-01 00:00:00

abstract：:Serum ferritin levels were monitored in nine patients with acute lymphoblastic leukemia (ALL), nine patients with acute nonlymphoblastic leukemia (ANLL), four patients with chronic myelogenous leukemia (CML), three patients with non-Hodgkin's lymphoma (NHL), and three patients with severe aplastic anemia (SAA) undergo...

journal_title：Cancer

authors： Or R,Matzner Y,Konijn AM

更新日期：1987-09-01 00:00:00

abstract：BACKGROUND:Several studies have shown that lysophosphatidic acid (LPA), a phospholipidic chemical mediator, is relevant to the pathogenesis of ovarian carcinoma. Higher plasma levels of LPA have been reported in patients with ovarian carcinoma than in healthy patients, and LPA is known to activate ovarian carcinoma cel...

journal_title：Cancer

authors： Tokumura A,Tominaga K,Yasuda K,Kanzaki H,Kogure K,Fukuzawa K

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:The development of novel therapeutic approaches for cancer therapy is important, especially for tumors that have poor response or develop resistance to standard chemotherapy and radiation. We discovered that noninvasive radiofrequency (RF) fields can affect cancer cells but not normal cells, inhibit progress...

journal_title：Cancer

authors： Curley SA,Palalon F,Lu X,Koshkina NV

更新日期：2014-11-01 00:00:00

abstract：:Patients with Philadelphia chromosome-positive chronic myelogenous leukemia (CML) were treated with a combination of alpha-interferon and gamma-interferon. Recombinant alpha-2a-interferon (Roferon-A, Hoffmann-LaRoche, Inc., Nutley, NJ) and recombinant gamma-interferon (Genentech, Inc., South San Francisco, CA) were ad...

journal_title：Cancer

authors： Talpaz M,Kurzrock R,Kantarjian H,Rothberg J,Saks S,Evans L,Gutterman JU

更新日期：1991-11-15 00:00:00

abstract：:Breast cancer is the most common malignant tumor among women in the world. In 2005, there were approximately 272,000 new cases diagnosed and more than 70,000 deaths from breast cancer in China. Of the patients who are newly diagnosed with breast cancer each year, approximately 3% to 10% have distant metastases at the ...

journal_title：Cancer

authors： Xu B,Hu X,Feng J,Geng C,Jin F,Li H,Li M,Li Q,Liao N,Liu D,Liu J,Liu Q,Lu J,Liu Z,Ma F,Ouyang Q,Pan Y,Shen K,Sun T,Teng Y,Tong Z,Wang B,Wang H,Wang S,Wang S,Wang T,Wang X,Wang X,Wang Y,Wang Z,Wu

更新日期：2020-08-15 00:00:00

abstract：:A pathology review of breast cancers in Japanese and Caucasian women indicates more numerous in situ carcinomas in the Japanese. Carcinomas with uniform nuclei were also more numerous among Japanese. Japanese women showed more extensive lymphocytic infiltrates adjacent to their tumors than did Caucasian women, and als...

journal_title：Cancer

authors： Stemmermann GN,Catts A,Fukunaga FH,Horie A,Nomura AM

更新日期：1985-07-01 00:00:00

abstract：BACKGROUND:Epithelioid sarcoma is a highly malignant soft tissue tumor that is largely resistant to conventional chemotherapy and radiotherapy. Because paclitaxel has been proven to be effective in other human malignancies refractory to conventional chemotherapy, the authors analyzed the in vitro growth inhibitory effe...

journal_title：Cancer

authors： Reinecke P,Knopf C,Schmitz M,Schneider EM,Gabbert HE,Gerharz CD

更新日期：2000-04-01 00:00:00

abstract：BACKGROUND AND METHODS:A univariate and multivariate analysis for the correlation between histomorphologic factors and prognosis was made using data from 1116 patients with soft tissue sarcoma, including 1005 cases available with complete histologic and follow-up data. RESULTS:The overall 5-year survival rate was 43.6...

journal_title：Cancer

authors： Hashimoto H,Daimaru Y,Takeshita S,Tsuneyoshi M,Enjoji M

更新日期：1992-12-15 00:00:00

abstract：:Prostatic intra-epithelial neoplasia (PIN, or intraductal dysplasia) is considered a precursor of invasive carcinoma, characterized by proliferation and anaplasia of cells lining prostatic ducts and acini. The highest grade of PIN, Grade 3, is thought to represent carcinoma in situ. To quantitate the degree of disrupt...

journal_title：Cancer

authors： Bostwick DG,Brawer MK

更新日期：1987-02-15 00:00:00

abstract：BACKGROUND:There is controversy regarding the optimal management of thyroid cancer. The proportion of patients with low-risk thyroid cancer who received radioactive iodine (RAI) treatment increased over the last 20 years, and little is known about the role played by clinicians in hospital-level RAI use for low-risk dis...

journal_title：Cancer

authors： Haymart MR,Banerjee M,Yang D,Stewart AK,Koenig RJ,Griggs JJ

更新日期：2013-01-15 00:00:00

abstract：BACKGROUND:The antiviral, proapoptotic, antiproliferative gene 2'-5' oligoadenylate synthetase (2-5OAS1) converts adenosine triphosphate into a series of 2'-5' oligoadenylates (2-5A). In turn, 2-5A activates latent ribonuclease (RNaseL), a candidate hereditary prostate cancer gene. OAS1 polymorphism (reference single n...

journal_title：Cancer

authors： Mandal S,Abebe F,Chaudhary J

更新日期：2011-12-15 00:00:00

abstract：BACKGROUND:Fatigue is a common and distressing symptom for patients with gynecologic cancers. Few studies have empirically examined whether it spontaneously resolves. This study was aimed at identifying longitudinal patterns of fatigue and predictors of clinically significant fatigue 1 year after treatment completion. ...

journal_title：Cancer

authors： Poort H,de Rooij BH,Uno H,Weng S,Ezendam NPM,van de Poll-Franse L,Wright AA

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:The lack of comparable metrics to evaluate prevention and early detection patient navigation programs impeded the ability to identify best practices. METHODS:The Prevention and Early Detection Workgroup of the Patient Navigation Leadership Summit was charged with making recommendations for common clinical m...

journal_title：Cancer

authors： Battaglia TA,Burhansstipanov L,Murrell SS,Dwyer AJ,Caron SE,Prevention and Early Detection Workgroup, National Patient Navigation Leadership Summit.

更新日期：2011-08-01 00:00:00

abstract：:Previous studies have indicated that OK-432 is a potent biologic response modifier (BRM) and that it augments immune responses to tumor cells. We studied the direct effect of OK-432 on tumor cells. Established and freshly derived human ovarian carcinoma lines were examined for their susceptibility to OK-432 or its sub...

journal_title：Cancer

authors： Nio Y,Zighelboim J,Berek J,Bonavida B

更新日期：1989-07-15 00:00:00

abstract：BACKGROUND:The incidence of bronchioloalveolar carcinoma of the lung (BAC), a pathologically distinct type of nonsmall cell lung carcinoma (NSCLC), appears to be rising. In this study, the authors compared data on the clinical presentation and clinical courses of patients with Stage IIIB and IV BAC with data on other t...

journal_title：Cancer

authors： Breathnach OS,Ishibe N,Williams J,Linnoila RI,Caporaso N,Johnson BE

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:Multimodality treatment has dramatically improved the outcome of patients with Ewing sarcoma. However, there appears to be little information concerning treatment-related complications in patients who are long-term survivors. METHODS:Forty-one patients with Ewing sarcoma who were treated between 1960-1980 a...

journal_title：Cancer

authors： Fuchs B,Valenzuela RG,Inwards C,Sim FH,Rock MG

更新日期：2003-12-15 00:00:00

abstract：BACKGROUND:Follow-through of a positive screening test is necessary to reap the potential benefits of cancer screening. Racial variation in follow-through diagnostic care may underlie a proportion of the known disparity in prostate cancer mortality. The authors used data from the screening arm of the Prostate, Lung, Co...

journal_title：Cancer

authors： Barocas DA,Grubb R 3rd,Black A,Penson DF,Fowke JH,Andriole G,Crawford ED

更新日期：2013-06-15 00:00:00

abstract：BACKGROUND:Onycholysis has been reported in association with the use of several noncytotoxic drugs and with chemotherapy in 135 patients. Onycholysis may be precipitated by exposure to ultraviolet radiation. METHODS:The authors studied 91 patients who received paclitaxel and 187 patients who received doxorubicin. RES...

journal_title：Cancer

authors： Hussain S,Anderson DN,Salvatti ME,Adamson B,McManus M,Braverman AS

更新日期：2000-05-15 00:00:00

abstract：BACKGROUND:The Early Lung Cancer Action Project (ELCAP) is designed to evaluate baseline and annual repeat screening by low radiation dose computed tomography (low-dose CT) in persons at high-risk for lung cancer. The authors report on the baseline screening experience. For full evaluation of screening, they await the ...

journal_title：Cancer

authors： Henschke CI

更新日期：2000-12-01 00:00:00

abstract：:The National Cancer Institute (NCI) has increased its emphasis in cancer prevention by undertaking a number of human intervention trials. Special emphasis is placed on chemoprevention, diet, and smoking and tobacco use. Some 24 clinical trials are ongoing in chemoprevention to assess the role of specific chemicals (na...

journal_title：Cancer

authors： Cullen JW

更新日期：1988-10-15 00:00:00

abstract：:Small-cell lung cancer (SCLC) represents 15% to 20% of all lung carcinomas. Approximately 30% to 40% of these cases are diagnosed in patients older than 70 years of age. Staging of SCLC classifies patients as having either limited or extensive-stage disease. The standard treatment for limited-stage disease is platinum...

journal_title：Cancer

authors： Pallis AG,Shepherd FA,Lacombe D,Gridelli C

更新日期：2010-03-01 00:00:00

abstract：:Twenty-four children aged 3 months to 18 years (median, 12 years) were treated for neurogenic sarcoma at the Children's Hospital of Philadelphia Cancer Research Center from 1958 through 1984. Sixteen patients had neurofibromatosis (NF). The tumors arose in an extremity or in the trunk (15 patients), the retroperitoneu...

journal_title：Cancer

authors： Raney B,Schnaufer L,Ziegler M,Chatten J,Littman P,Jarrett P

更新日期：1987-01-01 00:00:00

abstract：:It was shown previously that invasive human transitional cell carcinoma cell line EJ, but not the noninvasive RT4 cells, can degrade basement membrane laminin and that the degradation of basement membrane laminin was a result of a redistribution of activated cysteine proteinase cathepsin B to the plasma membrane of th...

journal_title：Cancer

authors： Redwood SM,Liu BC,Weiss RE,Hodge DE,Droller MJ

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND:Metastatic adenocarcinoma in the liver with an unidentified primary tumor site is a common clinical problem. Pathologists often are asked to identify the primary tumor site. The histologic picture itself usually is not helpful, because the histology may be similar in the metastases of tumors with different p...

journal_title：Cancer

authors： Tot T

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:The sensitivity of the intraoperative diagnosis of sentinel lymph node (SLN) micrometastases and the metastases of invasive lobular carcinoma (ILC) is low. The goal of the current study was to assess whether the use of intraoperative, rapid immunohistochistochemistry (IHC) enhances the intraoperative detecti...

journal_title：Cancer

authors： Leikola JP,Toivonen TS,Krogerus LA,von Smitten KA,Leidenius MH

更新日期：2005-07-01 00:00:00

abstract：:During 1982 and 1983, 4496 new cases were recorded in the French Registry of acute leukemia and myelodysplastic syndromes by the French Group of Hematologic Morphology. This cooperative group associated members of 37 university centers spread throughout France; these centers handle the overwhelming majority of acute l...

journal_title：Cancer

authors：

更新日期：1987-09-15 00:00:00

abstract：:Malignant thymoma is a relatively rare condition and a review of the literature reveals approximately 100 reported cases. Only a small percentage of these have been treated with megavoltage radiation therapy; therefore, it is difficult to find the necessary information to establish a proper time-dose relationship for ...

journal_title：Cancer

authors： Marks RD Jr,Wallace KM,Pettit HS

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND:The poor prognosis reported for patients with high-grade glial neoplasms indicates a need for the development of multimodality therapeutic approaches. The addition of chemotherapy has contributed variably to increased survival. The objective of the current study (Southwest Oncology Group [SWOG] 9016) was to ...

journal_title：Cancer

authors： Blumenthal DT,Rankin C,Eyre HJ,Livingston RB,Spence AM,Stelzer KJ,Rushing EJ,Berger MS,Rivkin SE,Cohn AL,Petersdorf SH

更新日期：2008-08-01 00:00:00