The role of clinicians in determining radioactive iodine use for low-risk thyroid cancer.

Abstract:

BACKGROUND:There is controversy regarding the optimal management of thyroid cancer. The proportion of patients with low-risk thyroid cancer who received radioactive iodine (RAI) treatment increased over the last 20 years, and little is known about the role played by clinicians in hospital-level RAI use for low-risk disease. METHODS:Thyroid surgeons affiliated with 368 hospitals that had Commission on Cancer-accredited cancer programs were surveyed. Survey data were linked to data reported to the National Cancer Database. A multivariable analysis was used to assess the relation between clinician decision makers and hospital-level RAI use after total thyroidectomy in patients with stage I, well differentiated thyroid cancer. RESULTS:The survey response rate was 70% (560 of 804 surgeons). The surgeon was identified as the primary decision maker by 16% of the surgeons; the endocrinologist was identified as the primary decision maker by 69%, and a nuclear medicine, radiologist, or other physician was identified as the primary decision maker by 15%. In a multivariable analysis controlling for hospital case volume and hospital type, when the primary decision maker was in a specialty other than endocrinology or surgery, there was greater use of RAI at the hospital (P < .001). A greater number of providers at the hospital where RAI was administered and having access to a tumor board also were associated with increased use of RAI (P < .001 and P = .006, respectively). CONCLUSIONS:The specialty of the primary decision maker, the number of providers administering RAI, and having access to a tumor board were associated significantly with the use of RAI for stage I thyroid cancer. The findings have implications for addressing nonclinical variation between hospitals, with a marked heterogeneity in decision making suggesting that standardization of care will be challenging.

journal_name

Cancer

journal_title

Cancer

authors

Haymart MR,Banerjee M,Yang D,Stewart AK,Koenig RJ,Griggs JJ

doi

10.1002/cncr.27721

subject

Has Abstract

pub_date

2013-01-15 00:00:00

pages

259-65

issue

2

eissn

0008-543X

issn

1097-0142

journal_volume

119

pub_type

杂志文章

相关文献

CANCER文献大全
  • Clinical implications of cytogenetic studies in cutaneous T-cell lymphoma (CTCL).

    abstract::Detailed cytogenetic studies were performed in 41 patients with cutaneous T-cell lymphoma (CTCL): four patients had limited plaques, 13 patients had generalized plaques, eight patients had cutaneous tumors, 16 patients had generalized erythroderma, and four additional patients, who had relatively benign chronic dermat...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19821015)50:8<1539::aid-cncr2820

    authors: Whang-Peng J,Bunn PA Jr,Knutsen T,Matthews MJ,Schechter G,Minna JD

    更新日期:1982-10-15 00:00:00

  • The risk for cancer among children of women who underwent in vitro fertilization.

    abstract:BACKGROUND:The possible association between ovarian carcinoma and ovulation-inducing drugs has led to renewed interest in the potential carcinogenic risks of these drugs. In vitro fertilization (IVF) has been linked to multiple pregnancies and possibly congenital malformations. However, to the authors' knowledge the as...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(20000615)88:12<2845::aid-cncr26>

    authors: Lerner-Geva L,Toren A,Chetrit A,Modan B,Mandel M,Rechavi G,Dor J

    更新日期:2000-06-15 00:00:00

  • Survival impact of surgical resection of primary tumor in patients with stage IV colorectal cancer: results from a large population-based cohort study.

    abstract:BACKGROUND:Currently, there is very low-quality evidence available regarding benefit of surgical resection of the primary tumor (SRPT), in patients with stage IV colorectal cancer (CRC). In the absence of randomization, the reported benefit may reflect selection of younger and healthier patients with good performance s...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.28464

    authors: Ahmed S,Leis A,Fields A,Chandra-Kanthan S,Haider K,Alvi R,Reeder B,Pahwa P

    更新日期:2014-03-01 00:00:00

  • Osteosarcoma of the soft tissue of the larynx: report of a case with light and electron microscopic studies.

    abstract::A case of osteosarcoma arising in the soft tissue of the larynx in an elderly man is presented with light and electron microscopic documentation. The patient developed chronic hoarseness and a recurring polypoid laryngeal tumor, causing acute airway obstruction. He was treated by total laryngectomy, but he died with m...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197811)42:5<2343::aid-cncr282042

    authors: Dahm LJ,Schaefer SD,Carder HM,Vellios F

    更新日期:1978-11-01 00:00:00

  • Relationship between cytokine gene single nucleotide polymorphisms and symptom burden and quality of life in lung cancer survivors.

    abstract:BACKGROUND:Previous research has demonstrated that many lung cancer survivors report difficulties with symptom control and experience a poor quality of life (QOL). Although recent studies have suggested a relationship of single nucleotide polymorphisms (SNPs) in several cytokine genes with cancer susceptibility and pro...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.25255

    authors: Rausch SM,Clark MM,Patten C,Liu H,Felten S,Li Y,Sloan J,Yang P

    更新日期:2010-09-01 00:00:00

  • A reversible enteropathy complicating continuous hepatic artery infusion chemotherapy with 5-fluoro-2-deoxyuridine.

    abstract::This article describes two patients with hepatic metastases from colorectal cancer in whom a reversible enteropathy developed during the administration of hepatic artery infusion chemotherapy with 5-fluoro-2-deoxyuridine (5-FUdR) via an Infusaid Series 400 pump (Infusaid Corp., Sharon, MA). Both patients had severe di...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19851115)56:10<2424::aid-cncr282

    authors: Gluck WL,Akwari OE,Kelvin FM,Goodwin BJ

    更新日期:1985-11-15 00:00:00

  • EphA2 overexpression is associated with angiogenesis in ovarian cancer.

    abstract:BACKGROUND:EphA2 is overexpressed in the majority of ovarian cancers and predicts poor clinical outcome. Based on EphA2's emerging role in angiogenesis, we hypothesized that tumors overexpressing EphA2 demonstrate greater microvessel density (MVD) and matrix metalloproteinase (MMP) expression. METHODS:After Institutio...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.22415

    authors: Lin YG,Han LY,Kamat AA,Merritt WM,Landen CN,Deavers MT,Fletcher MS,Urbauer DL,Kinch MS,Sood AK

    更新日期:2007-01-15 00:00:00

  • Primary fibrosarcoma of bone. A clinicopathologic study of 130 patients.

    abstract::One hundred thirty patients with histologically verified primary fibrosarcoma of bone, unassociated with any pre-existent benign bone condition, were treated at Memorial Sloan-Kettering Cancer Center between 1918 and 1973. This series of cases represents approximately 5% of primary malignant bone tumors treated in our...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197503)35:3<837::aid-cncr2820350

    authors: Huvos AG,Higinbotham NL

    更新日期:1975-03-01 00:00:00

  • The treatment of mycosis fungoides: adjuvant topical mechlorethamine after electron beam therapy.

    abstract::The feasibility of employing adjuvant topical mechlorethamine after electron beam therapy in the treatment of patients with mycosis fungoides is demonstrated. Patients treated with a planned adjuvant topical mechlorethamine schedule had a median disease-free interval of 25 months compared to 17 months for the group tr...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1002/1097-0142(197712)40:6<2851::aid-cncr282040

    authors: Price NM,Hoppe RT,Constantine VS,Fuks ZY,Farber EM

    更新日期:1977-12-01 00:00:00

  • Cervical adenocarcinoma and squamous cell carcinoma incidence trends among white women and black women in the United States for 1976-2000.

    abstract:BACKGROUND:Although cervical carcinoma incidence and mortality rates have declined in the U.S. greatly since the introduction of the Papanicolaou smear, this decline has not been uniform for all histologic subtypes. Therefore, the authors assessed the differential incidence rates of squamous cell carcinoma (SCC) and ad...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.20064

    authors: Wang SS,Sherman ME,Hildesheim A,Lacey JV Jr,Devesa S

    更新日期:2004-03-01 00:00:00

  • A Phase II clinical trial of idarubicin administered to children with relapsed brain tumors.

    abstract:BACKGROUND:Idarubicin (IDR), an anthracycline that is a derivative of daunorubicin, was synthesized in an attempt to find new analogs of daunorubicin with an improved spectrum of activity and diminished acute or chronic toxicity. Because of the favorable pharmacokinetic profile of IDR (with the persistence of its activ...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1002/(sici)1097-0142(19980815)83:4<813::aid-cnc

    authors: Arndt CA,Krailo MD,Steinherz L,Scheithauer B,Liu-Mares W,Reaman GH

    更新日期:1998-08-15 00:00:00

  • Transient neurologic disturbances induced by high-dose methotrexate treatment.

    abstract::Temporary neurologic abnormalities were detected in 9 of 60 patients undergoing treatment with high-dose methotrexate and citrovorum factor rescue (MTX-CF) for osteosarcoma. The incidence of abnormalities and abnormalities themselves were more severe than previously reported. This was attributed to an increased dose a...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19850915)56:6<1356::aid-cncr2820

    authors: Jaffe N,Takaue Y,Anzai T,Robertson R

    更新日期:1985-09-15 00:00:00

  • Correlation between genetic alteration and long-term clinical outcome of patients with oligodendroglial tumors, with identification of a consistent region of deletion on chromosome arm 1p.

    abstract:BACKGROUND:In oligodendroglial tumors, allelic losses on chromosome arms 1p and 19q are not only diagnostic molecular markers but also statistically significant predictors of both chemosensitivity and longer recurrence-free survival. In the current study, the authors attempted to analyze 21 patients genetically and cli...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.11322

    authors: Hashimoto N,Murakami M,Takahashi Y,Fujimoto M,Inazawa J,Mineura K

    更新日期:2003-05-01 00:00:00

  • Prognostic factors for clinically localized prostate carcinoma: analysis of 938 patients irradiated in the prostate specific antigen era.

    abstract:BACKGROUND:Pretreatment serum prostate specific antigen (PSA) level is a powerful prognostic factor for clinically localized prostate carcinoma. The traditional prognostic factors, T classification and Gleason score, appear to have been relegated to a minor position. This study was conducted to evaluate the relative pr...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:

    authors: Zagars GK,Pollack A,von Eschenbach AC

    更新日期:1997-04-01 00:00:00

  • Intraosseous well-differentiated osteosarcoma.

    abstract::A series of 27 patients with intramedullary osteogenic sarcomas that were so well-differentiated histologically as to be confused with benign lesions was studied. Of the 27 patients, 14 were females and 13 were males, and most were adults. The tibia and femur were involved commonly. Roentgenographically, the tumors sh...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197709)40:3<1337::aid-cncr282040

    authors: Unni KK,Dahlin DC,McLeod RA,Pritchard DJ

    更新日期:1977-09-01 00:00:00

  • Promoting colonoscopy screening among low-income Latinos at average risk of colorectal cancer: A randomized clinical trial.

    abstract:BACKGROUND:Screening colonoscopy (SC) for colorectal cancer (CRC) is underused by Latino individuals. The current randomized clinical trial examined the impact of 3 interventions: 1) patient navigation; 2) patient navigation plus standard Centers for Disease Control and Prevention print materials; and 3) patient naviga...

    journal_title:Cancer

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/cncr.32541

    authors: DuHamel KN,Schofield EA,Villagra C,Sriphanlop P,Itzkowitz SH,Cotter G,Cohen N,Erwin DO,Winkel G,Thompson HS,Zauber AG,Jandorf LH

    更新日期:2020-02-15 00:00:00

  • Influence of delay to diagnosis on prognostic indicators of screen-detected breast carcinoma.

    abstract:BACKGROUND:Although delay to diagnosis after a breast screening abnormality causes anxiety, its effect on prognosis is unknown. METHODS:Using pooled data from five Canadian organized breast cancer screening programs, the authors used unconditional logistic regression to evaluate the effect of delay to diagnosis on pro...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.10453

    authors: Olivotto IA,Gomi A,Bancej C,Brisson J,Tonita J,Kan L,Mah Z,Harrison M,Shumak R

    更新日期:2002-04-15 00:00:00

  • The effects of pain severity on health-related quality of life: a study of Chinese cancer patients.

    abstract:BACKGROUND:The health-related functioning of patients with cancer is compromised by several factors, including the disease process, treatment, and the various symptoms that are produced by both disease and treatment. This study was designed to specify the relationship between patients' pain severity and their self-repo...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:

    authors: Wang XS,Cleeland CS,Mendoza TR,Engstrom MC,Liu S,Xu G,Hao X,Wang Y,Ren XS

    更新日期:1999-11-01 00:00:00

  • Relationship between androgen receptor binding activity in human prostate cancer and clinical response to endocrine therapy.

    abstract::The authors investigated the ability of androgen receptor binding in prostate cancer tissue to predict the response of prostate cancer patients to endocrine therapy. The clinical response of 37 previously untreated patients with various grades and stages of prostate cancer was correlated with androgen receptor binding...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19870501)59:9<1599::aid-cncr2820

    authors: Benson RC Jr,Gorman PA,O'Brien PC,Holicky EL,Veneziale CM

    更新日期:1987-05-01 00:00:00

  • The mammalian target of rapamycin pathway is widely activated without PTEN deletion in renal cell carcinoma metastases.

    abstract:BACKGROUND:Inhibitors of the mammalian target of rapamycin (mTOR) are emerging as promising therapies for metastatic renal cell carcinoma (RCC). Because rational treatment strategies require understanding the activation status of the underlying signaling pathway being targeted at the desired stage of disease, the autho...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.25402

    authors: Abou Youssif T,Fahmy MA,Koumakpayi IH,Ayala F,Al Marzooqi S,Chen G,Tamboli P,Squire J,Tanguay S,Sircar K

    更新日期:2011-01-15 00:00:00

  • Analyzing predictive models following definitive radiotherapy for prostate carcinoma.

    abstract:BACKGROUND:As we approach the 21st century, clinically useful predictive models for prostate carcinoma are urgently needed to stratify patients reliably for future treatment strategies. Recently, many investigators have developed models that employ prostate specific antigen (PSA)-based constructs or groupings in an att...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0142(19970915)80:6<1093::aid-cn

    authors: Movsas B,Hanlon AL,Teshima T,Hanks GE

    更新日期:1997-09-15 00:00:00

  • Elective versus therapeutic radical neck dissection in epidermoid carcinoma of the oral cavity: results of a randomized clinical trial.

    abstract::This study concerns 75 patients with squamous cell carcinoma of the oral cavity who were patients at the Gustave-Roussy Institute between December 1966 and July 1973. These patients were divided into two groups. The first group was comprised of 39 patients who underwent elective radical neck dissection; nodal involvem...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1002/1097-0142(19800715)46:2<386::aid-cncr28204

    authors: Vandenbrouck C,Sancho-Garnier H,Chassagne D,Saravane D,Cachin Y,Micheau C

    更新日期:1980-07-15 00:00:00

  • DNA content and other prognostic features in childhood medulloblastoma. Proposal of a scoring system.

    abstract::The authors reviewed clinical features, surgical extent of resection, histologic parameters, and DNA content in 55 children with medulloblastomas and found that complete or near total resection, absence of tumor dissemination, tumor DNA aneuploidy, and low proliferative index correlated with a favorable clinical outco...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.2820690539

    authors: Schofield DE,Yunis EJ,Geyer JR,Albright AL,Berger MS,Taylor SR

    更新日期:1992-03-01 00:00:00

  • External beam radiation treatment for rectal cancer is associated with a decrease in subsequent prostate cancer diagnosis.

    abstract:BACKGROUND:External beam radiation therapy (EBRT) for rectal cancer unavoidably delivers significant radiation dose to the prostate gland. The effect of this incidental exposure on subsequent prostate cancer diagnosis was investigated using the Surveillance, Epidemiology, and End Results (SEER) cancer registry. METHOD...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.23241

    authors: Hoffman KE,Hong TS,Zietman AL,Russell AH

    更新日期:2008-02-15 00:00:00

  • Immunogenicity and safety of single-dose, 13-valent pneumococcal conjugate vaccine in pediatric and adolescent oncology patients.

    abstract:BACKGROUND:Children receiving immunosuppressive treatment for cancer are at high risk for invasive pneumococcal disease. The 13-valent pneumococcal conjugate vaccine (PCV13) can prevent pneumococcal disease in healthy children; however, there is an absence of literature regarding the benefit of PCV13 in immunocompromis...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.30764

    authors: Hung TY,Kotecha RS,Blyth CC,Steed SK,Thornton RB,Ryan AL,Cole CH,Richmond PC

    更新日期:2017-11-01 00:00:00

  • Evaluation of fluorescence polarization of human blood lymphocytes (SCM test) in the diagnosis of cancer.

    abstract::Fluorescence polarization was performed on 82 individuals: 32 patients with malignant diseases, 30 apparently healthy individuals, and 20 patients with nonmalignant diseases. The blood lymphocytes from these cases were isolated and challenged with cancer basic protein (CaBP). Stimulation occurred in the majority of th...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19800901)46:5<1164::aid-cncr2820

    authors: Schnuda ND

    更新日期:1980-09-01 00:00:00

  • Induction paclitaxel in previously untreated, resectable, advanced squamous cell carcinomas of head and neck.

    abstract:BACKGROUND:Previous Phase II trials evaluating paclitaxel as a single agent have produced objective response rates of 38-40%. However, in these studies patients had recurrent disease and had received previous treatment with chemotherapy, radiation, surgery, or some combination of the same. To the authors' knowledge, th...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/1097-0142(20001215)89:12<2587::aid-cncr11>

    authors: Grecula JC,Smith RE,Rhoades CA,Sharma P,Agrawal A,Zhang H,Allen J,Goldman FP,Young D,Schuller DE

    更新日期:2000-12-15 00:00:00

  • Treatment of intrahepatic malignancy with radiofrequency ablation: radiologic-pathologic correlation.

    abstract:BACKGROUND:Radiofrequency (RF)-induced tissue coagulation represents a new approach for the thermal destruction of tumors within the liver. The purpose of the current study was to 1) assess technique safety; 2) determine the extent and evolution of induced cellular damage; and 3) correlate the observed pathologic effec...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:

    authors: Goldberg SN,Gazelle GS,Compton CC,Mueller PR,Tanabe KK

    更新日期:2000-06-01 00:00:00

  • Acute myelocytic leukemia following prolonged streptozotocin therapy.

    abstract::A 69-year-old man with metastatic islet cell carcinoma was treated with streptozotocin and achieved excellent tumor regression. Sixty-seven grams of streptozotocin were given over 28 months. After completion of streptozotocin therapy, the patient had progressive leukopenia. Thirteen months after discontinuation of str...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19810415)47:8<1963::aid-cncr2820

    authors: Green MR,Anderson RE

    更新日期:1981-04-15 00:00:00

  • Atypical squamous cells of undetermined significance on cervical smears: follow-up study of an Asian screening population.

    abstract:BACKGROUND:The current study reports on the significance of cervical smears identified as atypical squamous cells of undetermined significance (ASCUS) in the largest Asian screening population to date. METHODS:From January 1998 to December 1999, 190,000 cervical smears were evaluated by the cervical cytology laborator...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.20045

    authors: Cheung AN,Szeto EF,Ng KM,Fong KW,Yeung AC,Tsun OK,Khoo US,Chan KY,Ng AW

    更新日期:2004-04-25 00:00:00