A phase II study alternating alpha-2a-interferon and gamma-interferon therapy in patients with chronic myelogenous leukemia.

abstract：BACKGROUND:Recent advances in the treatment of nasopharyngeal carcinoma (NPC) have transpired into better treatment outcomes for patients with locoregionally advanced NPC, and have broadened the chemotherapeutic options for patients with metastatic disease. METHODS:Data for this review were identified through searches...

journal_title：Cancer

authors： Ma BB,Chan AT

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:For this report, the authors comprehensively summarized the existing literature on patients with pineoblastoma and identified the variables and treatments that had an impact patient on outcomes. METHODS:A comprehensive search identified 109 studies that collectively described the outcomes of patients with p...

journal_title：Cancer

authors： Tate M,Sughrue ME,Rutkowski MJ,Kane AJ,Aranda D,McClinton L,McClinton L,Barani IJ,Parsa AT

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Preoperative chemoradiation improves survival in esophageal and gastroesophageal junction (GEJ) cancer. We evaluated irinotecan and cisplatin as induction chemotherapy followed by concurrent chemoradiation in esophageal cancer. METHODS:Patients with uT1N1M0 or uT2-4NanyM0 resectable squamous cancer or adeno...

journal_title：Cancer

authors： Ilson DH,Minsky BD,Ku GY,Rusch V,Rizk N,Shah M,Kelsen DP,Capanu M,Tang L,Campbell J,Bains M

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:A hypothesis generated a retrospective analysis of the improvement of survival over time in patients with cutaneous melanoma (CM) in order to identify factors contributing to this progress. METHODS:A cohort of 4791 patients diagnosed with primary CM in southern Germany between 1976 and 2001 was analyzed. Ka...

journal_title：Cancer

authors： Lasithiotakis KG,Leiter U,Eigentler T,Breuninger H,Metzler G,Meier F,Garbe C

更新日期：2007-03-15 00:00:00

abstract：BACKGROUND:Lobular neoplasia (LN), also known as lobular carcinoma in situ, is an incidental histologic finding in tissue removed at breast surgery. Patients with LN are known to be predisposed to develop invasive or intraductal carcinoma (CA). This study investigates factors that influence the cancer risk in LN patien...

journal_title：Cancer

authors： Bodian CA,Perzin KH,Lattes R

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:To elucidate the influence of long term interferon administration on the rate of occurrence of hepatocellular carcinoma (HCC) in patients with hepatitis B virus (HBV)-related cirrhosis, the authors analyzed 313 consecutive patients with cirrhosis. METHODS:Of the 313 patients, 94 underwent long term intermit...

journal_title：Cancer

authors： Ikeda K,Saitoh S,Suzuki Y,Kobayashi M,Tsubota A,Fukuda M,Koida I,Arase Y,Chayama K,Murashima N,Kumada H

更新日期：1998-03-01 00:00:00

abstract：:Seventeen patients with adenocystic carcinoma have received 34 adequate trials of chemotherapy at Princess Margaret Hospital since 1969. There have been five objective responses to chemotherapy in 4 cases, lasting from five to 24 months, and 3 other patients have had stabilized disease for a period of five to seven mo...

journal_title：Cancer

authors： Tannock IF,Sutherland DJ

更新日期：1980-08-01 00:00:00

abstract：:Gonadal dosimetry and spermatogenic activity was monitored in patients given radiation therapy (RT) after unilateral orchiectomy for seminoma. The RT given was, with minor variations, 3200 rad in 16 fractions in four weeks to the para-aortic and ipsilateral pelvic inguinal lymphatics in order to include the orchiectom...

journal_title：Cancer

authors： Hahn EW,Feingold SM,Simpson L,Batata M

更新日期：1982-07-15 00:00:00

abstract：BACKGROUND:Vitiligo is a dermatologic disease characterized by local, dispersed, or diffuse white patches on the skin. The disease is defined as an autoimmune disorder because autoantibodies against membranal components of melanocytes are found in the patients' sera. The current study examined whether the autoantibodie...

journal_title：Cancer

authors： Fishman P,Azizi E,Shoenfeld Y,Sredni B,Yecheskel G,Ferrone S,Zigelman R,Chaitchik S,Floro S,Djaldetti M

更新日期：1993-10-15 00:00:00

abstract：:Sarcoma of the breast represents less than 1% of primary mammary malignancies; this study reports 25 such cases. The largest group had malignant fibrous histiocytoma (44%), followed by liposarcoma (24%) and fibrosarcoma (16%). Also represented were clear cell sarcoma, neurogenic sarcoma, leiomyosarcoma, and alveolar s...

journal_title：Cancer

authors： Pollard SG,Marks PV,Temple LN,Thompson HH

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND:The objective of this study was to assess the impact of a prostate-specific antigen (PSA) complete response (PSA-CR), measured at the end of external-beam radiotherapy and short-term hormone therapy, on treatment outcomes. METHODS:The phase 3 Radiation Therapy Oncology Group 9413 trial, as part of its origi...

journal_title：Cancer

authors： Cury FL,Hunt D,Roach M 3rd,Shipley W,Gore E,Hsu IC,Krisch RE,Seider MJ,Sandler H,Lawton C

更新日期：2013-06-01 00:00:00

abstract：:Six cases of desmoplastic melanoma were studied by light and electron microscopy. The tumors fulfilled one or more of the following criteria: (1) having the presence of atypical intraepidermal melanocytic proliferation bordering the primary lesions; (2) an antecedent history of melanoma at the site of recurrence; (3) ...

journal_title：Cancer

authors： DiMaio SM,Mackay B,Smith JL Jr,Dickersin GR

更新日期：1982-12-01 00:00:00

abstract：:Nineteen patients with locally advanced bladder cancer were treated with irradiation and concomitant 5-fluorouracil intravenous infusion with or without bolus mitomycin. Eighteen of the 19 patients were evaluated for local response. Eleven of the 18 patients (61%) obtained a complete local response within 3 to 6 month...

journal_title：Cancer

authors： Rotman M,Macchia R,Silverstein M,Aziz H,Choi K,Rosenthal J,Braverman A,Laungani GB

更新日期：1987-02-15 00:00:00

abstract：BACKGROUND:LAMP3 is a newly described hypoxia regulated gene of potential interest in hypoxia-induced therapy resistance and metastasis. The prognostic value of LAMP3 in breast cancer was investigated. METHODS:Expression levels of LAMP3 in breast cancer cell lines and patient tissues were determined by real-time polym...

journal_title：Cancer

authors： Nagelkerke A,Mujcic H,Bussink J,Wouters BG,van Laarhoven HW,Sweep FC,Span PN

更新日期：2011-08-15 00:00:00

abstract：:Arylsulfatase B activity has been determined in 24-hour urine samples from 243 patients with colorectal cancer. Elevated activity of the enzyme was obsereved in 172 out of 243 (71%) patients. Employing Dukes' modified classification of colorectal cancer, urine arylsulfatase B activity was elevated in Dukes' A lesions-...

journal_title：Cancer

authors： Morgan LR Jr,Samuels MS,Thomas W,Krementz ET,Meeker W

更新日期：1975-12-01 00:00:00

abstract：BACKGROUND:This study was performed to develop a sensitive method for the detection of circulating hepatocellular carcinoma (HCC) cells in peripheral blood, in advance of the diagnosis of distant metastasis of HCC by conventional means. METHODS:Peripheral blood (5 ml) samples were obtained from 64 patients with HCC an...

journal_title：Cancer

authors： Komeda T,Fukuda Y,Sando T,Kita R,Furukawa M,Nishida N,Amenomori M,Nakao K

更新日期：1995-05-01 00:00:00

abstract：:The incidence of ovarian cancer in Rochester, Minnesota over the 40-year period 1935 through 1974 was determined; and risk factors for epithelial ovarian cancer occurring in Rochester from 1945 to 1974 were examined in 116 patients and 464 controls. Among the characteristics studied, only nulliparity was found to be a...

journal_title：Cancer

authors： Annegers JF,Strom H,Decker DG,Dockerty MB,O'Fallon WM

更新日期：1979-02-01 00:00:00

abstract：BACKGROUND:Uterine leiomyosarcoma (ULMS) is identified in 0.1% to 0.2% of hysterectomy specimens of presumed leiomyoma. To date, there is no preoperative technique that reliably differentiates ULMS from uterine leiomyoma. Increasing use of minimally invasive approaches for the management of leiomyomas may result in ina...

journal_title：Cancer

authors： George S,Barysauskas C,Serrano C,Oduyebo T,Rauh-Hain JA,Del Carmen MG,Demetri GD,Muto MG

更新日期：2014-10-15 00:00:00

abstract：BACKGROUND:To assess the ability of [(18)F]fluorodeoxyglucose (F-18 FDG) positron emission tomography (PET) to predict the viability of residual masses after chemotherapy in patients with metastatic nonseminomatous germ cell tumors (GCT), PET results were compared in a blinded analysis with computed tomography (CT) sca...

journal_title：Cancer

authors： Kollmannsberger C,Oechsle K,Dohmen BM,Pfannenberg A,Bares R,Claussen CD,Kanz L,Bokemeyer C

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:After surgical resection, the residual, invasive glioblastoma (GBM) cells give rise to a recurrent tumor, which, in 96% of patients, arises adjacent to the resection margin. METHODS:In this study, the authors prospectively enrolled 25 patients with GBM who underwent gross total resection followed by adjuvan...

journal_title：Cancer

authors： Mangiola A,de Bonis P,Maira G,Balducci M,Sica G,Lama G,Lauriola L,Anile C

更新日期：2008-08-15 00:00:00

abstract：:The study is a clinicopathologic report on 64 patients with primary adenocarcinoma of the urinary bladder and urachus, with particular reference to important prognostic and therapeutic factors. All tumors exhibited adenocarcinomatous features in at least two thirds of the examined tumor area. Pure forms of the differe...

journal_title：Cancer

authors： Anderström C,Johansson SL,von Schultz L

更新日期：1983-10-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to identify genome-wide single nucleotide variants and mutations in African American patients with colorectal cancer (CRC). There is a need of such studies in African Americans, because they display a higher incidence of aggressive CRC tumors. METHODS:We performed whole exome s...

journal_title：Cancer

authors： Ashktorab H,Daremipouran M,Devaney J,Varma S,Rahi H,Lee E,Shokrani B,Schwartz R,Nickerson ML,Brim H

更新日期：2015-01-01 00:00:00

abstract：:Forty-five immunocompetent patients with solid tumors were immunized with BCG, PPD, and tumor cells. The methods were practical, but the morbidity was significant, including painful draining ulcerations at vaccine sites, possible enhancement of tumor growth in three patients, and the discovery at autopsy of systemic t...

journal_title：Cancer

authors： Gerner RE,Moore GE

更新日期：1976-07-01 00:00:00

abstract：:Flow cytometry was used to compare binding of wheat germ agglutinin (WGA) and Lens culinaris lectin (Lcl) to peripheral lymphocytes (PBL) from normal subjects and 26 patients with chronic lymphocytic leukemia (CLL). As defined by the interactions of WGA and Lcl with cell surface receptors, normal unfractionated PBL an...

journal_title：Cancer

authors： Boldt DH,Nelson MO

更新日期：1983-06-01 00:00:00

abstract：BACKGROUND:There is limited published evidence regarding the efficacy of total skin electron beam radiation for patients with the diffuse erythrodermic form of mycosis fungoides. METHODS:Forty-five patients with erythrodermic mycosis fungoides were managed at McMaster University in Hamilton, Ontario, Canada (n=34), an...

journal_title：Cancer

authors： Jones GW,Rosenthal D,Wilson LD

更新日期：1999-05-01 00:00:00

abstract：:The glucocorticoid receptor (GR) quantitation by a whole-cell assay and/or cytosol technique and the in vitro sensitivity to steroids have been assessed in peripheral blood cells from normal donors and patients with chronic lymphatic leukemia (CLL), acute lymphoblastic leukemia (ALL), lymphosarcoma cell leukemia (LSCL...

journal_title：Cancer

authors： Nanni P,Nicoletti G,Prodi G,Galli MC,De Giovanni C,Grilli S,Lollini PL,Gobbi M,Cavo M,Tura S

更新日期：1982-02-15 00:00:00

abstract：:Fifteen oncocytic (oxyphilic granular cell) neoplasms of the salivary glands collected from three large university medical centers are presented. The histologic and ultrastructural criteria that characterize oncocytes are presented and electron micrographs of two of our cases are discussed. Included in the series are ...

journal_title：Cancer

authors： Gray SR,Cornog JL Jr,Seo IS

更新日期：1976-09-01 00:00:00

abstract：:The relationships between cigarette smoking, occupational exposures, dietary vitamin A and lung cancer is explored in a case-control study. The study is based on 1002 primary lung cancers among white men and 1119 white male controls between 35 and 79 years of age admitted to Roswell Park Memorial Institute from 1957 t...

journal_title：Cancer

authors： Vena JE,Byers TE,Cookfair D,Swanson M

更新日期：1985-08-15 00:00:00

abstract：:In this study the authors applied flow cytometric DNA-ploidy analysis to multiple female genital tract malignant tumors in 43 patients, most of whom (n = 37) had bilateral ovarian cancer. An algorithm was developed for calculation of the likelihood ratio of the probabilities that measured DNA index differences between...

journal_title：Cancer

authors： Smit VT,Fleuren GJ,van Houwelingen JC,Zegveld ST,Kuipers-Dijkshoorn NJ,Cornelisse CJ

更新日期：1990-10-15 00:00:00

abstract：BACKGROUND:Cardiovascular disease (CVD) is the leading cause of death among patients with early-stage breast cancer (BC), but adherence to cardiovascular disease risk factor (CVD-RF) medications is reported to be poor in BC survivors. The objective of the current study was to determine the association between nonadhere...

journal_title：Cancer

authors： Hershman DL,Accordino MK,Shen S,Buono D,Crew KD,Kalinsky K,Trivedi MS,Hur C,Hu J,Unger JM,Wright JD

更新日期：2020-04-01 00:00:00