Breast sarcoma. A clinicopathologic review of 25 cases.

Abstract:

:Sarcoma of the breast represents less than 1% of primary mammary malignancies; this study reports 25 such cases. The largest group had malignant fibrous histiocytoma (44%), followed by liposarcoma (24%) and fibrosarcoma (16%). Also represented were clear cell sarcoma, neurogenic sarcoma, leiomyosarcoma, and alveolar soft part sarcoma (4% each). Of 19 patients treated by wide local excision or simple mastectomy with or without adjuvant radiotherapy, 11 had local recurrence develop, of which one patient died and nine of the remaining ten had metastases develop. Of the remaining eight patients in this group with no local recurrence, only two had metastases develop. Of the six patients treated by radical or Patey mastectomy, none had local recurrence develop, but two died of metastases. No patient had metastases develop more than 5 years after diagnosis. Regional lymph node involvement with tumor was observed in only one patient (with malignant fibrous histiocytoma) despite regional lymphadenopathy in seven. The overall mortality at 5 years is 64% but does not increase thereafter. The authors' findings suggest that failure to establish local control is associated with a poor prognosis and that wide local excision or simple mastectomy does not provide sufficient clearance to be used as first-line treatment. Excision of the axillary lymphatics and adjuvant radiotherapy are unlikely to be beneficial.

journal_name

Cancer

journal_title

Cancer

authors

Pollard SG,Marks PV,Temple LN,Thompson HH

doi

10.1002/1097-0142(19900901)66:5<941::aid-cncr28206

subject

Has Abstract

pub_date

1990-09-01 00:00:00

pages

941-4

issue

5

eissn

0008-543X

issn

1097-0142

journal_volume

66

pub_type

杂志文章

相关文献

CANCER文献大全
  • Breast conservation therapy in the United States following the 1990 National Institutes of Health Consensus Development Conference on the treatment of patients with early stage invasive breast carcinoma.

    abstract:BACKGROUND:A National Institutes of Health (NIH) Consensus Development Conference on the treatment of patients with early stage invasive breast carcinoma, held in June 1990, recommended breast conservation therapy for the majority of women with Stage I or II breast carcinoma. The authors evaluated the national use of b...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:

    authors: Lazovich D,Solomon CC,Thomas DB,Moe RE,White E

    更新日期:1999-08-15 00:00:00

  • Correlation between increased granulocyte elastase release and activation of blood coagulation in patients with lung cancer.

    abstract:BACKGROUND:Coagulopathies often are associated with malignant tumors. The pathogenesis of these complications in cancer is not clear. Host inflammatory (monocyte/macrophage) cell-mediated triggering of clotting activation has been suggested. METHODS:The objective of this study was to evaluate the role of neutrophil-de...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19931001)72:7<2134::aid-cncr2820

    authors: Gabazza E,Taguchi O,Yamakami T,Machishi M,Ibata H,Suzuki S

    更新日期:1993-10-01 00:00:00

  • Transvaginal sonography as a screening method for ovarian cancer. A report of the first 1000 cases screened.

    abstract::From November 1987 to April 1989, 1000 women 40 years or older underwent screening vaginal sonography at the University of Kentucky Medical Center (Lexington, KY). Patients included in this investigation were all asymptomatic and had no known pelvic abnormalities. Each ovary was measured in three planes and ovarian vo...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19900201)65:3<573::aid-cncr28206

    authors: van Nagell JR Jr,Higgins RV,Donaldson ES,Gallion HH,Powell DE,Pavlik EJ,Woods CH,Thompson EA

    更新日期:1990-02-01 00:00:00

  • Apical lung carcinoma.

    abstract::During the period 1955 to 1975, 63 consecutive cases of apical lung carcinoma were treated in the Radiation Therapy Division of the University of Michigan Medical Center (UMMC). Supervoltage external radiation alone or combination of radiation and surgery were the main modalities of treatment used in these patients. O...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19840901)54:5<913::aid-cncr28205

    authors: Ahmad K,Fayos JV,Kirsh MM

    更新日期:1984-09-01 00:00:00

  • Comparison of tumor pathology with duration of survival of North American patients with hepatocellular carcinoma.

    abstract:BACKGROUND:Several of the large studies addressing prognosis and survival from hepatocellular carcinoma (HCC) have been from Europe and Asia, but only a few have emanated from North America. Survival statistics from other parts of the world may not be applicable to the North American population because of etiologic, de...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19950815)76:4<579::aid-cncr28207

    authors: Nzeako UC,Goodman ZD,Ishak KG

    更新日期:1995-08-15 00:00:00

  • Synchronous neoplasms in patients with diminutive colorectal adenomas.

    abstract::The distribution of synchronous neoplasms was retrospectively analyzed in 220 patients undergoing initial colonoscopic evaluation for colorectal neoplasms. In 159 of the 220 patients, an index neoplasm was present in the rectosigmoid region. Of these 159 patients, 32 had an index rectosigmoid adenoma less than 5 mm in...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19871001)60:7<1599::aid-cncr2820

    authors: Tripp MR,Morgan TR,Sampliner RE,Kogan FJ,Protell RL,Earnest DL

    更新日期:1987-10-01 00:00:00

  • Laparoscopic extraperitoneal para-aortic lymphadenectomy in locally advanced cervical cancer: a prospective correlation of surgical findings with positron emission tomography/computed tomography findings.

    abstract:BACKGROUND:Failure to detect metastasis to para-aortic nodes in patients with locally advanced cervical cancer leads to suboptimal treatment. No previous studies have prospectively compared positron emission tomography (PET)/computed tomography (CT) with laparoscopic extraperitoneal staging in the evaluation of para-ao...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/cncr.25739

    authors: Ramirez PT,Jhingran A,Macapinlac HA,Euscher ED,Munsell MF,Coleman RL,Soliman PT,Schmeler KM,Frumovitz M,Ramondetta LM

    更新日期:2011-05-01 00:00:00

  • Cancer trends among Hispanic men in South Florida, 1981-1998.

    abstract:BACKGROUND:Hispanics now represent a majority of residents in Miami-Dade County, Florida. In this report, the authors present new cancer incidence and mortality data for South Florida's Hispanic men for the period 1990-1998 and compare them with data from a previous report from the 1980s. Periodic updating of cancer in...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:

    authors: Wilkinson JD,Wohler-Torres B,Trapido E,Fleming LE,MacKinnon J,Voti L,Peace S

    更新日期:2002-02-15 00:00:00

  • Relationship between androgen receptor binding activity in human prostate cancer and clinical response to endocrine therapy.

    abstract::The authors investigated the ability of androgen receptor binding in prostate cancer tissue to predict the response of prostate cancer patients to endocrine therapy. The clinical response of 37 previously untreated patients with various grades and stages of prostate cancer was correlated with androgen receptor binding...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19870501)59:9<1599::aid-cncr2820

    authors: Benson RC Jr,Gorman PA,O'Brien PC,Holicky EL,Veneziale CM

    更新日期:1987-05-01 00:00:00

  • A prospective randomized trial of thalidomide with topotecan compared with topotecan alone in women with recurrent epithelial ovarian carcinoma.

    abstract:BACKGROUND:Thalidomide is an antiangiogenic agent with immune modulating potential. The objective of this study was to determine response rates among women who were treated for recurrent ovarian cancer using topotecan with or without thalidomide. METHODS:Women were enrolled in this multicenter, prospective, randomized...

    journal_title:Cancer

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/cncr.23164

    authors: Downs LS Jr,Judson PL,Argenta PA,Ghebre R,Geller MA,Bliss RL,Boente MP,Nahhas WA,Abu-Ghazaleh SZ,Chen MD,Carson LF

    更新日期:2008-01-15 00:00:00

  • Infants younger than 1 year of age with rhabdomyosarcoma.

    abstract::Of a total of 1561 patients registered in the Intergroup Rhabdomyosarcoma Study (IRS) as of May 1983, 78 patients (5%) were younger than 1 year of age. These infants did not differ from the older children (1-20 years of age) in male/female ratio, clinical grouping, or survival rates. Infants younger than 1 year of age...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19861215)58:12<2606::aid-cncr282

    authors: Ragab AH,Heyn R,Tefft M,Hays DN,Newton WA Jr,Beltangady M

    更新日期:1986-12-15 00:00:00

  • Manual dissection of adenocarcinoma of the lower third of the rectum specimens for detection of lymph node metastases smaller than 5 mm.

    abstract:BACKGROUND:The question of whether manual dissection when searching for metastatic lymph nodes from rectal cancer (less than 5 mm) is a reliable method remains controversial. METHODS:We examined 50 consecutive cases of primary adenocarcinoma of the rectum treated with a sphincter-sparing total rectum resection, total ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/(SICI)1097-0142(19960215)77:4<607::AID-CNC

    authors: Andreola S,Leo E,Belli F,Bufalino R,Tomasic G,Lavarino C,Baldini MT,Meroni E

    更新日期:1996-02-15 00:00:00

  • A clinicopathologic study of 92 cases of granulosa cell tumor of the ovary with special reference to the factors influencing prognosis.

    abstract::Ninety-two cases of granulosa cell tumor of the ovary have been studied. The clinical and pathologic data from this group were similar to that obtained in previous series. Because of the long natural history of many granulosa cell tumors, crude death rates over a relatively short period give little indication of the t...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197501)35:1<231::aid-cncr2820350

    authors: Fox H,Agrawal K,Langley FA

    更新日期:1975-01-01 00:00:00

  • Detection of tumor cells in the portal and peripheral blood of patients with colorectal carcinoma using competitive reverse transcriptase-polymerase chain reaction.

    abstract:BACKGROUND:In spite of many reports, it remains unclear whether the presence of tumor cells in circulating blood flow predicts a poor prognosis. METHODS:Competitive seminested reverse transcriptase-polymerase chain reaction (RT-PCR), a technique for the quantitative detection of tumor cells, was applied to detect the ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(20010901)92:5<1251::aid-cncr1445

    authors: Sadahiro S,Suzuki T,Tokunaga N,Yurimoto S,Yasuda S,Tajima T,Makuuchi H,Murayama C,Matsuda K

    更新日期:2001-09-01 00:00:00

  • Long-term trends in the incidence rates of upper digestive tract cancer in the Netherlands Antilles.

    abstract::Data from the Cancer Registry in the Netherlands Antilles made clear that the incidence rate of cancer of the upper digestive tract in this country was among the highest in the world. To study the long-term trends in the incidence rate a retrospective population-based case-finding survey was performed. The author pres...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19840401)53:7<1618::aid-cncr2820

    authors: Freni SC

    更新日期:1984-04-01 00:00:00

  • Carcinocythemia (carcinoma cell leukemia) due to metastatic carcinoma of the breast: report of a case.

    abstract::A patient with a 17-year course of metastatic lobular carcinoma of the breast is described who developed large numbers of circulating carcinoma cells which were easily detectable in several routine peripheral blood smears shortly before death. This rare complication of carcinoma has been called "carcinocythemia." Carc...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197712)40:6<3107::aid-cncr282040

    authors: Myerowitz RL,Edwards PA,Sartiano GP

    更新日期:1977-12-01 00:00:00

  • Obesity and screening for breast, cervical, and colorectal cancer in women: a review.

    abstract::The literature examining obesity as a barrier to screening for breast, cervical, and colorectal cancer has not been evaluated systematically. With the increasing prevalence of obesity and its impact on cancer incidence and mortality, it is important to determine whether obesity is a barrier to screening so that cancer...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/cncr.23408

    authors: Cohen SS,Palmieri RT,Nyante SJ,Koralek DO,Kim S,Bradshaw P,Olshan AF

    更新日期:2008-05-01 00:00:00

  • A compound follicular-parafollicular cell carcinoma of the thyroid: a new tumor entity?

    abstract::An unusual thyroid carcinoma is described, showing structural, histochemical and radioimmunologic features of both a follicular and a parafollicular cell carcinoma. Radioimmunoassay revealed high levels of thyroglobulin in the patient's serum and in extracts from metastatic tumor tissue. Immunoreactive thyroglobulin w...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19830915)52:6<1053::aid-cncr2820

    authors: Ljungberg O,Ericsson UB,Bondeson L,Thorell J

    更新日期:1983-09-15 00:00:00

  • Prognosis in adult acute myelogenous leukemia related to performance status and other factors.

    abstract::Pretreatment factors of prognostic value were sought in 54 consecutively treated cases of adult acute myelogenous leukemia. Twenty of 37 patients with a good (greater than 50%) pretreatment Karnofsky performance status (P.S.) achieved complete remission (C.R.), while only 1/17 with a poor P.S. achieved C.R. This diffe...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197607)38:1<329::aid-cncr2820380

    authors: Kansal V,Omura GA,Soong SJ

    更新日期:1976-07-01 00:00:00

  • The prognostic significance of ploidy analysis in operable breast cancer.

    abstract::The nuclear DNA content of 98 operable breast cancers was determined by flow cytometric analysis using paraffin-embedded tissue. All patients were on follow-up and failure of treatment or recurrences were identified. DNA ploidy data in the form of ploidy status and DNA index (DI) has been correlated with various clini...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19911215)68:12<2612::aid-cncr282

    authors: Sharma S,Mishra MC,Kapur BM,Verma K,Nath I

    更新日期:1991-12-15 00:00:00

  • Oxaliplatin and capecitabine in the treatment of patients with recurrent or refractory carcinoma of unknown primary site: a phase 2 trial of the Sarah Cannon Oncology Research Consortium.

    abstract:BACKGROUND:Despite the widespread use of oxaliplatin-based regimens for colorectal and other gastrointestinal cancers, there is surprisingly little information regarding their empiric use for the treatment of carcinoma of unknown primary site (CUP). In the current study, the combination of oxaliplatin and capecitabine ...

    journal_title:Cancer

    pub_type: 杂志文章,多中心研究

    doi:10.1002/cncr.25029

    authors: Hainsworth JD,Spigel DR,Burris HA 3rd,Shipley D,Farley C,Macias-Perez IM,Barton J,Greco FA

    更新日期:2010-05-15 00:00:00

  • Changes associated with the development of resistance to imatinib (STI571) in two leukemia cell lines expressing p210 Bcr/Abl protein.

    abstract:BACKGROUND:Although various mechanisms have been recognized as being associated with the development of resistance to imatinib mesylate in vitro and in clinical situations, their relative significance and contributions remain poorly understood, as is the sequence of events leading to the selection of the resistant phen...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.20131

    authors: Scappini B,Gatto S,Onida F,Ricci C,Divoky V,Wierda WG,Andreeff M,Dong L,Hayes K,Verstovsek S,Kantarjian HM,Beran M

    更新日期:2004-04-01 00:00:00

  • Probably benign lesions at breast magnetic resonance imaging: preliminary experience in high-risk women.

    abstract:BACKGROUND:The purpose of the current study was to determine the frequency of 'probably benign' interpretations at breast magnetic resonance (MR) imaging screening of high-risk women and the frequency of subsequent malignancy in these women. METHODS:The authors performed a retrospective review of the records of 367 as...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.11491

    authors: Liberman L,Morris EA,Benton CL,Abramson AF,Dershaw DD

    更新日期:2003-07-15 00:00:00

  • Everolimus in combination with octreotide long-acting repeatable in a first-line setting for patients with neuroendocrine tumors: an ITMO group study.

    abstract:BACKGROUND:Preclinical and clinical studies suggest synergistic activity between somatostatin analogues and mammalian target of rapamycin inhibitors. The activity and safety of everolimus was assessed in combination with octreotide long-acting repeatable (LAR) in patients with neuroendocrine tumors (NETs) of gastroente...

    journal_title:Cancer

    pub_type: 杂志文章,多中心研究

    doi:10.1002/cncr.28726

    authors: Bajetta E,Catena L,Fazio N,Pusceddu S,Biondani P,Blanco G,Ricci S,Aieta M,Pucci F,Valente M,Bianco N,Mauri CM,Spada F

    更新日期:2014-08-15 00:00:00

  • Thromboprophylaxis with low-molecular-weight heparin in medical patients with cancer.

    abstract::Venous thromboembolism (VTE) is a frequent complication of cancer and cancer treatment and is associated with multiple clinical consequences, including recurrent VTE, bleeding, and an increase in the risk of death. Although the risks associated with VTE have been well recognized in surgical cancer patients, there is a...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/cncr.24665

    authors: Lyman GH

    更新日期:2009-12-15 00:00:00

  • Influence of delay to diagnosis on prognostic indicators of screen-detected breast carcinoma.

    abstract:BACKGROUND:Although delay to diagnosis after a breast screening abnormality causes anxiety, its effect on prognosis is unknown. METHODS:Using pooled data from five Canadian organized breast cancer screening programs, the authors used unconditional logistic regression to evaluate the effect of delay to diagnosis on pro...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.10453

    authors: Olivotto IA,Gomi A,Bancej C,Brisson J,Tonita J,Kan L,Mah Z,Harrison M,Shumak R

    更新日期:2002-04-15 00:00:00

  • Suicide risk among cancer survivors: Head and neck versus other cancers.

    abstract:BACKGROUND:Cancer survivors face psychosocial issues that increase their risk of suicide. This study examined the risk of suicide across cancer sites, with a focus on survivors of head and neck cancer (HNC). METHODS:The Surveillance, Epidemiology, and End Results 18-registry database (from 2000 to 2014) was queried fo...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.31675

    authors: Osazuwa-Peters N,Simpson MC,Zhao L,Boakye EA,Olomukoro SI,Deshields T,Loux TM,Varvares MA,Schootman M

    更新日期:2018-10-15 00:00:00

  • A randomized phase 3 trial comparing nimotuzumab plus cisplatin chemoradiotherapy versus cisplatin chemoradiotherapy alone in locally advanced head and neck cancer.

    abstract:BACKGROUND:Because the addition of nimotuzumab to chemoradiation in patients with locally advanced head and neck cancer improved outcomes in a phase 2 study, the authors conducted a phase 3 study to confirm these findings. METHODS:This open-label, investigator-initiated, phase 3, randomized trial was conducted from 20...

    journal_title:Cancer

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/cncr.32179

    authors: Patil VM,Noronha V,Joshi A,Agarwal J,Ghosh-Laskar S,Budrukkar A,Murthy V,Gupta T,Mahimkar M,Juvekar S,Arya S,Mahajan A,Agarwal A,Purandare N,Rangarajan V,Balaji A,Chaudhari SV,Banavali S,Kannan S,Bhattacharjee A,D

    更新日期:2019-09-15 00:00:00

  • Quantitative imaging of cancer in the postgenomic era: Radio(geno)mics, deep learning, and habitats.

    abstract::Although cancer often is referred to as "a disease of the genes," it is indisputable that the (epi)genetic properties of individual cancer cells are highly variable, even within the same tumor. Hence, preexisting resistant clones will emerge and proliferate after therapeutic selection that targets sensitive clones. He...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/cncr.31630

    authors: Napel S,Mu W,Jardim-Perassi BV,Aerts HJWL,Gillies RJ

    更新日期:2018-12-15 00:00:00

  • Radiation-related myocardial injury. Management of two cases.

    abstract::Pericardial effusion and trifascicular block developed 5 years following mediastinal irradiation for Hodgkin's disease in a 19-year-old patient. Another 24-year-old patients had an acute myocardial infarction followed by severe angina pectoris 5 years following mediastinal irradiation for the same disease. A pericardi...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197611)38:5<1941::aid-cncr282038

    authors: Ali MK,Kahlil KG,Fuller LM,Leachman RD,Sullivan MP,Loh KK,Gamble JF,Shullenberger CC

    更新日期:1976-11-01 00:00:00