Infants younger than 1 year of age with rhabdomyosarcoma.

Abstract:

:Of a total of 1561 patients registered in the Intergroup Rhabdomyosarcoma Study (IRS) as of May 1983, 78 patients (5%) were younger than 1 year of age. These infants did not differ from the older children (1-20 years of age) in male/female ratio, clinical grouping, or survival rates. Infants younger than 1 year of age had a significantly greater frequency of undifferentiated sarcoma, 18% versus 7% in older children (P less than 0.005). Infants also had a significantly greater proportion of cancers with botryoid pathology, 10% versus 4% in older children (P less than 0.005). When reviewed by the newly proposed IRS cytopathologic classification, there was no difference in pathologic types between the two age groups. Infants younger than 1 year of age had a higher rate of bladder-prostate-vagina primary tumor sites than older children, 24% versus 10% (P less than 0.05). In addition, infants tended to receive less of the prescribed doses of chemotherapy and radiation therapy than older children, and to develop more toxicity to treatment than older children. Despite these differences, the overall survival curve for the two age groups appears to be similar. In contrast to Wilms' tumor and neuroblastoma, in which age (less than 1 year) is a favorable prognostic factor, age does not appear to be an important prognostic factor in rhabdomyosarcoma.

journal_name

Cancer

journal_title

Cancer

authors

Ragab AH,Heyn R,Tefft M,Hays DN,Newton WA Jr,Beltangady M

doi

10.1002/1097-0142(19861215)58:12<2606::aid-cncr282

subject

Has Abstract

pub_date

1986-12-15 00:00:00

pages

2606-10

issue

12

eissn

0008-543X

issn

1097-0142

journal_volume

58

pub_type

杂志文章

相关文献

CANCER文献大全
  • Curative radiotherapy in the malignant lymphomas.

    abstract::The clinical experience and technologic improvements of the past 40 years are briefly summarized in terms of their contributions to the present optimistic and aggressive approach to the treatment of malignant lymphoma. The reasoning behind the large-field moderately high-dose technique that has evolved is reviewed and...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(196810)22:4<752::aid-cncr2820220

    authors: Nobler MP

    更新日期:1968-10-01 00:00:00

  • Nonaspirin nonsteroidal anti-inflammatory drugs and gastric cancer risk after Helicobacter pylori eradication: A territory-wide study.

    abstract:BACKGROUND:Despite Helicobacter pylori (HP) eradication, individuals can still develop gastric cancer (GC). Prior studies have demonstrated that nonaspirin nonsteroidal anti-inflammatory drugs (NA-NSAIDs) reduce the risk of GC, but this may be caused by immortal time bias and failure to adjust for HP status. The object...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.33412

    authors: Li B,Cheung KS,Wong IY,Leung WK,Law S

    更新日期:2021-01-20 00:00:00

  • Glandular cardiac myxomas. Histologic, immunohistochemical, and ultrastructural evidence of epithelial differentiation.

    abstract::Histologic, histochemical, immunocytochemical, and ultrastructural features of two cardiac myxomas containing glandular elements are reported. Glandular elements in both cases stained positively with both mucicarmine and periodic acid-Schiff reagent with diastase pretreatment (DPAS). Immunoperoxidase studies demonstra...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19870515)59:10<1767::aid-cncr282

    authors: Goldman BI,Frydman C,Harpaz N,Ryan SF,Loiterman D

    更新日期:1987-05-15 00:00:00

  • Chromosome rearrangement at 17q25 and xp11.2 in alveolar soft-part sarcoma: A case report and review of the literature.

    abstract:BACKGROUND:Despite the characteristic histopathologic appearance of alveolar soft-part sarcoma (ASPS), its histogenesis remains unclear, and cytogenetic analysis of ASPS is limited to eight cases so far because of the extreme rarity of this disease. METHODS:The authors document a cytogenetic study of a primary case of...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:

    authors: Joyama S,Ueda T,Shimizu K,Kudawara I,Mano M,Funai H,Takemura K,Yoshikawa H

    更新日期:1999-10-01 00:00:00

  • Medroxyprogesterone acetate inhibits human pancreatic carcinoma cell growth by inducing apoptosis in association with Bcl-2 phosphorylation.

    abstract:BACKGROUND:A previous study found that medroxyprogesterone acetate (MPA) delayed the in vivo growth of three (AsPC-1, Capan-2, and MiaPaCa-2) of nine human pancreatic carcinoma cell lines transplanted into nude mice (Cancer 1995; 75:1263-72). The current study was undertaken to evaluate the basis for this inhibitor. M...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:

    authors: Abe M,Yamashita J,Ogawa M

    更新日期:2000-05-01 00:00:00

  • Prolymphocytic leukemia: treatment with combination chemotherapy to include doxorubicin.

    abstract::Prolymphocytic leukemia (PL) is a clinically distinct leukemic disorder. Cytochemical and surface marker characteristics help to differentiate PL from other types of leukemia, including chronic lymphocytic leukemia (CLL). In contrast to patients with CLL, those with PL frequently require early therapeutic intervention...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19820415)49:8<1524::aid-cncr2820

    authors: Taylor HG,Butler WM,Rhoads J,Karcher DS,Detrick-Hooks B

    更新日期:1982-04-15 00:00:00

  • Thomsen-Friedenreich antigen presents as a prognostic factor in colorectal carcinoma: A clinicopathologic study of 264 patients.

    abstract:BACKGROUND:Up to now, the expression of the tumor-associated Thomsen-Friedenreich (TF) antigen in colorectal carcinoma has not been thoroughly investigated with particular emphasis on its correlation with established clinicopathologic characteristics and classifications as well as its prognostic relevance. METHODS:For...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:

    authors: Baldus SE,Zirbes TK,Hanisch FG,Kunze D,Shafizadeh ST,Nolden S,Mönig SP,Schneider PM,Karsten U,Thiele J,Hölscher AH,Dienes HP

    更新日期:2000-04-01 00:00:00

  • Orbital lymphoid neoplasms: a clinicopathologic study of 60 patients.

    abstract::Sixty cases of orbital lymphoid neoplasms originally accessioned as malignant lymphomas were analyzed histopathologically and the follow-up data evaluated separately for each category as follows: inflammatory pseudo-tumor, 5; reactive lymphoid hyperplasia, 8; atypical lymphoid hyperplasia, 7; and malignant lymphocytic...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19800801)46:3<576::aid-cncr28204

    authors: Knowles DM 2nd,Jakobiec FA

    更新日期:1980-08-01 00:00:00

  • Expression of orphan nuclear receptor NR4A2 in gastric cancer cells confers chemoresistance and predicts an unfavorable postoperative survival of gastric cancer patients with chemotherapy.

    abstract:BACKGROUND:NR4A2, an orphan nuclear receptor essential in the generation of dopaminergic neurons, has been recently linked to inflammation and cancer. This study sought to identify the role of NR4A2 on chemoresistance and postoperative prognosis of gastric cancer (GC). METHODS:NR4A2 was transfected into GC cells to in...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.28228

    authors: Han Y,Cai H,Ma L,Ding Y,Tan X,Chang W,Guan W,Liu Y,Shen Q,Yu Y,Zhang H,Cao G

    更新日期:2013-10-01 00:00:00

  • Changing trends. An overview of breast cancer incidence and mortality.

    abstract::The incidence of breast cancer rose about 1% per year between 1940 and 1980 according to data in the Connecticut Tumor Registry. A sharp increase of 32% was reported between 1980 and 1987 in the Surveillance, Epidemiology and End Results Program of the National Cancer Institute. Data from this program shows that the i...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.2820741304

    authors: Garfinkel L,Boring CC,Heath CW Jr

    更新日期:1994-07-01 00:00:00

  • Decision-support networks of women newly diagnosed with breast cancer.

    abstract:BACKGROUND:Little is known about the size and characteristics of the decision-support networks of women newly diagnosed with breast cancer and whether their involvement improves breast cancer treatment decisions. METHODS:A population-based sample of patients newly diagnosed with breast cancer in 2014 and 2015, as repo...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.30848

    authors: Wallner LP,Li Y,McLeod MC,Hamilton AS,Ward KC,Veenstra CM,An LC,Janz NK,Katz SJ,Hawley ST

    更新日期:2017-10-15 00:00:00

  • Targeted radiotherapy with [(90)Y]-SMT 487 in mice bearing human nonsmall cell lung tumor xenografts induced to express human somatostatin receptor subtype 2 with an adenoviral vector.

    abstract:BACKGROUND:Novel approaches to increasing the therapeutic efficacy of targeted radiotherapy of cancer are required. One strategy to achieve this goal is to induce high-level expression of a receptor on the surface of tumor cells that can be targeted with a radiolabeled peptide. The objectives of this study were to 1) i...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.10300

    authors: Rogers BE,Zinn KR,Lin CY,Chaudhuri TR,Buchsbaum DJ

    更新日期:2002-02-15 00:00:00

  • Maturation-induction of tumor cells using a human colon carcinoma model.

    abstract::The establishment of a maturation-induction model using human colon cancer cells as targets is reported. Two colon carcinoma cell lines were established from human tumors; one line was heterogeneous and was cloned into two distant subpopulations. Cells from these lines and clones and cells from an established human co...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19800315)45:5+<1178::aid-cncr282

    authors: Dexter DL,Hager JC

    更新日期:1980-03-15 00:00:00

  • Evaluation of three cervical cancer detection programs in Japan with special reference to cost-benefit analysis.

    abstract::Three screening programs for early cervical cancer currently in use in Japan were evaluated according to the following criteria: (1) economic effectiveness; (2) screening efficiency; and (3) access to medical care. The mobile program has the highest benefit-cost ratio (BCR, 1.20) and is hence most cost-effective; its ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19850515)55:10<2514::aid-cncr282

    authors: Takenaga N,Kai I,Ohi G

    更新日期:1985-05-15 00:00:00

  • Bone marrow manifestations of Hodgkin's disease.

    abstract::Bone marrow trephine biopsies were performed on 107 previously untreated patients with Hodgkin's disease (HD). Fifteen patients (14%) exhibited bone marrow involvement. These consisted of two of three patients (67%) with lymphocyte depletion, six of 27 patients (22%) with mixed cellularity, five of 64 patients (8%) wi...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197610)38:4<1717::aid-cncr282038

    authors: O'Carroll DI,McKenna RW,Brunning RD

    更新日期:1976-10-01 00:00:00

  • OVX1 as a marker for early stage endometrial carcinoma.

    abstract:BACKGROUND:Endometrial carcinoma is generally diagnosed only after the onset of postmenopausal bleeding. Although most patients with Stage I disease can be cured, the prognosis worsens significantly when the tumor is no longer confined to the uterine corpus. Serum CA 125 is elevated in only 10-20% cases of Stage I and ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19940401)73:7<1855::aid-cncr2820

    authors: Xu FJ,Yu YH,Daly L,Anselmino L,Hass GM,Berchuck A,Rodriguez GC,Soper JT,Clarke-Pearson DL,Hollis D

    更新日期:1994-04-01 00:00:00

  • Acute and delayed nausea and emesis control in pediatric oncology patients.

    abstract:BACKGROUND:To the authors' knowledge there is little information available regarding the effectiveness of standard antiemetic therapy among cancer patients who receive emetogenic chemotherapy in clinical practice, especially in the pediatric population. The current study was undertaken to determine the effectiveness of...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.21631

    authors: Holdsworth MT,Raisch DW,Frost J

    更新日期:2006-02-15 00:00:00

  • Combination versus successive single agent chemotherapy in lymphocytic lymphoma.

    abstract::Fifty-three patients with advanced lymphocytic lymphoma were randomly assigned to treatment with the combination cyclophosphamide, vincristine, and prednisone (CVP) or the same agents used successively in maximal doses (C-V-P). Complete remissions occurred in 68% with CVP and 48% with C-V-P. For patients with nodular ...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1002/1097-0142(197801)41:1<23::aid-cncr28204101

    authors: Kennedy BJ,Bloomfield CD,Kiang DT,Vosika G,Peterson BA,Theologides A

    更新日期:1978-01-01 00:00:00

  • Sensitive detection of circulating hepatocellular carcinoma cells in peripheral venous blood.

    abstract:BACKGROUND:This study was performed to develop a sensitive method for the detection of circulating hepatocellular carcinoma (HCC) cells in peripheral blood, in advance of the diagnosis of distant metastasis of HCC by conventional means. METHODS:Peripheral blood (5 ml) samples were obtained from 64 patients with HCC an...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19950501)75:9<2214::aid-cncr2820

    authors: Komeda T,Fukuda Y,Sando T,Kita R,Furukawa M,Nishida N,Amenomori M,Nakao K

    更新日期:1995-05-01 00:00:00

  • Mental disorders in cancer patients: a study of 100 psychiatric referrals.

    abstract::Records of 100 consecutive hospitalized cancer patients referred for psychiatric consultation were reviewed. These patients constituted only 5% of those seen by the Psychiatry Consultation Service during the study period. Fifty-six percent of the referred patients were diagnosed as depressed and 40% as having organic ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197809)42:3<1385::aid-cncr282042

    authors: Levine PM,Silberfarb PM,Lipowski ZJ

    更新日期:1978-09-01 00:00:00

  • Oral fluorouracil therapy of hepatoma.

    abstract::Oral fluorouracil was administered weekly to 12 consecutive patients with unresectable hepatoma. Six patients showed an objective response with a significant increase in survival duration compared to nonresponders and to untreated patients. The clinical features of these cases are discussed, along with details of ther...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197705)39:5<1930::aid-cncr282039

    authors: Kennedy PS,Lehane DE,Smith FE,Lane M

    更新日期:1977-05-01 00:00:00

  • Prognostic factors in pediatric spinal cord astrocytoma.

    abstract:BACKGROUND:Factors that could optimize the management of pediatric spinal cord astrocytoma remain unclear and controversial. METHODS:To determine the factors that influence the prognosis of pediatric patients with spinal cord astrocytomas, a series of 73 consecutive patients at 13 French treatment centers with histolo...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0142(19981201)83:11<2391::aid-c

    authors: Bouffet E,Pierre-Kahn A,Marchal JC,Jouvet A,Kalifa C,Choux M,Dhellemmes P,Guérin J,Tremoulet M,Mottolese C

    更新日期:1998-12-01 00:00:00

  • Obesity is associated with breast cancer in African-American women but not Hispanic women in South Los Angeles.

    abstract:BACKGROUND:Obesity is considered a risk factor for breast cancer. Modifying life styles that reduce obesity offers the potential for prevention and improved outcomes from cancer. The effects of obesity and breast cancer among African-American women and Hispanic women have been explored in a limited number of studies. T...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.25956

    authors: Sarkissyan M,Wu Y,Vadgama JV

    更新日期:2011-08-15 00:00:00

  • Prognostic value of the plasminogen activation system in patients with gastric carcinoma.

    abstract:BACKGROUND:Patients with gastric cancer have a poor prognosis and can be cured by surgery only if the cancer is detected in an early stage. Extended surgery, down staging with chemotherapy before operation, and new postoperative treatments are recent approaches to increase survival rates. Categorizing patients' prognos...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0142(19960315)77:6<1035::aid-cn

    authors: Ganesh S,Sier CF,Heerding MM,van Krieken JH,Griffioen G,Welvaart K,van de Velde CJ,Verheijen JH,Lamers CB,Verspaget HW

    更新日期:1996-03-15 00:00:00

  • Peripheral B- and T-lymphocyte counts in patients with sarcoma and breast carcinoma.

    abstract::Peripheral B- and T-lymphocyte counts were studied in 50 patients before they received any therapy for their conditions: 16 had carcinoma of the breast; 8 soft tissue sarcoma; and 26, benign disease. Among 11 males, the six patients with advanced soft tissue sarcoma had significantly lower percentages of T lymphocytes...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197708)40:2<667::aid-cncr2820400

    authors: Lee YT,Marshall GJ,Weiner J,Bateman JR

    更新日期:1977-08-01 00:00:00

  • Impact of state-specific Medicaid reimbursement and eligibility policies on receipt of cancer screening.

    abstract:BACKGROUND:Although state Medicaid programs cover cancer screening, Medicaid beneficiaries are less likely to be screened for cancer and are more likely to present with tumors of an advanced stage than are those with other insurance. The current study was performed to determine whether state Medicaid eligibility and re...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.28704

    authors: Halpern MT,Romaire MA,Haber SG,Tangka FK,Sabatino SA,Howard DH

    更新日期:2014-10-01 00:00:00

  • Adenosquamous carcinoma of the gallbladder warrants resection only if curative resection is feasible.

    abstract:BACKGROUND:Adenosquamous/squamous cell carcinoma of the gallbladder generally has been considered a lethal disease. The objective of this study was to clarify the effectiveness of resection for patients with adenosquamous/squamous cell carcinoma of the gallbladder. METHODS:Twenty-nine patients who underwent resection ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.10578

    authors: Oohashi Y,Shirai Y,Wakai T,Nagakura S,Watanabe H,Hatakeyama K

    更新日期:2002-06-01 00:00:00

  • Transbronchial lung biopsy in the diagnosis of lymphangitic carcinomatosis.

    abstract::The clinical diagnosis of lymphangitic carcinomatosis of the lung has generally been confirmed by open lung or transthoracic needle biopsy, precedures with significant morbidity and mortality, particularly in patients with respiratory insufficiency. We present six cases of lymphangitic carcinomatosis diagnosed by tran...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197810)42:4<1995::aid-cncr282042

    authors: Aranda C,Sidhu G,Sasso LA,Adams FV

    更新日期:1978-10-01 00:00:00

  • Cystic adrenal neoplasms.

    abstract:BACKGROUND:Cystic lesions of the adrenal gland are uncommon and demonstrate a spectrum of histologic changes and may vary from pseudocysts to malignant cystic neoplasms. METHODS:The authors analyzed a series of primary cystic lesions of the adrenal gland to evaluate the clinicopathologic features and histologic spectr...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.20555

    authors: Erickson LA,Lloyd RV,Hartman R,Thompson G

    更新日期:2004-10-01 00:00:00

  • Medical oncology and geriatric medicine: is it time for fellowship integration?

    abstract::Although training programs exist in both medical oncology and geriatrics (approved by the American Board of Internal Medicine), neither is adequate to ensure an appropriate supply of physicians to assume a leadership role in the treatment of the increasing number of geriatric patients who have or will develop a malign...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0142(19971001)80:7<1351::aid-cn

    authors: Bennett JM,Sahasrabudhe DM,Hall WJ

    更新日期:1997-10-01 00:00:00