Obesity is associated with breast cancer in African-American women but not Hispanic women in South Los Angeles.

abstract：BACKGROUND:Whether fatherhood status affects prostate cancer risk remains controversial. Recently, it was proposed that childless men are at lower prostate cancer risk than men with children and that men with sons may be at lower risk than men with daughters only. METHODS:National population-based register data were u...

journal_title：Cancer

authors： Jørgensen KT,Pedersen BV,Johansen C,Frisch M

更新日期：2008-02-15 00:00:00

abstract：:Clofarabine is a new-generation nucleoside analog that has been synthesized to combine the most favorable pharmacokinetic properties of its congeners fludarabine and cladribine. In addition to inhibition of DNA polymerases and DNA synthesis, clofarabine acts as a strong inhibitor of ribonucleotide reductase (RnR), an ...

journal_title：Cancer

authors： Faderl S,Gandhi V,Keating MJ,Jeha S,Plunkett W,Kantarjian HM

更新日期：2005-05-15 00:00:00

abstract：BACKGROUND:Periosteal osteosarcoma is a rare variant of osteosarcoma. Wide surgical removal is the mainstay of treatment, but controversy remains about the role of chemotherapy. The objective of this study was to review and analyze the clinical and treatment-related factors that influence the survival of patients with ...

journal_title：Cancer

authors： Cesari M,Alberghini M,Vanel D,Palmerini E,Staals EL,Longhi A,Abate M,Ferrari C,Balladelli A,Ferrari S

更新日期：2011-04-15 00:00:00

abstract：BACKGROUND:Patients with advanced soft tissue sarcomas (STS) have limited therapeutic options. Sorafenib (BAY 43-9006) is a multitargeted tyrosine kinase inhibitor of raf, vascular endothelial growth factor receptors 1 (VEGFR1) through 3, platelet-derived growth factor B, fms-like tyrosine kinase 3, and c-kit, and some...

journal_title：Cancer

authors： von Mehren M,Rankin C,Goldblum JR,Demetri GD,Bramwell V,Ryan CW,Borden E

更新日期：2012-02-01 00:00:00

abstract：:Chondrosarcoma of the foot is a very unusual entity. A case arising from a solitary osteocartilagenous exostosis is presented and the literature is reviewed and discussed. ...

journal_title：Cancer

authors： Lewis MM,Marcove RC,Bullough PG

更新日期：1975-08-01 00:00:00

abstract：:Knowledge of tumor antigenic expression is crucial to the design of therapeutic strategy. A murine monoclonal antibody (BE4) against a human melanoma membrane antigen, was used to study the in vitro expression of this antigen. By membrane immunofluorescence, BE4 reacted against 5 of 8 melanoma lines as compared to zer...

journal_title：Cancer

authors： Leong SP,Bolen JL,Chee DO,Smith VR,Taylor JC,Benfield JR,Klevecz RR

更新日期：1985-03-15 00:00:00

abstract：BACKGROUND:Patients with hereditary leiomyomatosis and renal cell carcinoma (HLRCC) resulting from fumarate hydratase (FH) mutations may present with skin, uterine, and renal tumors, with each having unique pathologic features. This study investigated the association between prospectively identified suspicious patholog...

journal_title：Cancer

authors： Kopp RP,Stratton KL,Glogowski E,Schrader KA,Rau-Murthy R,Russo P,Coleman JA,Offit K

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:DNA flow cytometry of hepatocellular carcinoma (HCC) cells has been investigated in many studies, but, to the best of our knowledge, there are no data on DNA analysis of cirrhotic parenchyma around the HCC. In this study, cell kinetics and ploidy of parenchymal cells around HCC were performed to ascertain if...

journal_title：Cancer

authors： Ruà S,Comino A,Fruttero A,Torchio P,Bouzari H,Taraglio S,Torchio B,Capussotti L

更新日期：1996-09-15 00:00:00

abstract：BACKGROUND:Multifocal tumor areas occurred in 12-22% of patients with renal cell carcinoma. It is unknown whether these tumors have malignant potential and characterize a higher risk for metastases. The performance of nephron-sparing surgery in patients with low grade or low stage tumors is controversial. METHODS:Prim...

journal_title：Cancer

authors： Junker K,Schlichter A,Junker U,Knöfel B,Kosmehl H,Schubert J,Claussen U

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:In spite of many reports, it remains unclear whether the presence of tumor cells in circulating blood flow predicts a poor prognosis. METHODS:Competitive seminested reverse transcriptase-polymerase chain reaction (RT-PCR), a technique for the quantitative detection of tumor cells, was applied to detect the ...

journal_title：Cancer

authors： Sadahiro S,Suzuki T,Tokunaga N,Yurimoto S,Yasuda S,Tajima T,Makuuchi H,Murayama C,Matsuda K

更新日期：2001-09-01 00:00:00

abstract：:Of 387 patients who died with lung cancer, 28 cases were reviewed (7.2%) which were clinically undiagnosed. The male:female ratio was 3.6 and mean age was 64 years in the males, 47 years in the females. The most frequent presenting symptoms were neurologic. Prior to death, 21 patients had known or suspected metastatic...

journal_title：Cancer

authors： Clary CF,Michel RP,Wang NS,Hanson RE

更新日期：1983-01-15 00:00:00

abstract：BACKGROUND:There is global variation in the onset of hepatocellular carcinoma (HCC). The objective of the current study was to investigate the impact of country of birth on age at the time of HCC diagnosis in the United States. METHODS:Incident HCC cases diagnosed between 2000 and 2012 in the Surveillance, Epidemiolog...

journal_title：Cancer

authors： Yang JD,Altekruse SF,Nguyen MH,Gores GJ,Roberts LR

更新日期：2017-01-01 00:00:00

abstract：:Few studies have incorporated high-dose methotrexate (MTX) with leucovorin rescue in the treatment of small cell lung cancer (SCLC). Potentially therapeutic levels of MTX can be achieved in the central nervous system (CNS) by systemic administration of high doses of this drug. Utilizing a combination chemotherapy prog...

journal_title：Cancer

authors： Neijstrom ES,Capizzi RL,Rudnick SA,Kirsch M,Delaney D,Kahn L,Lipper S,Carney C

更新日期：1983-03-15 00:00:00

abstract：:In 186 women with breast cancer, there was a progressive increase in the proportion of axillary nodal involvement as the number of pregnancies increased from zero to two or more (P = 0.026). Logistic regression analysis demonstrated that this effect was independent of the known relationship of age and tumor size to no...

journal_title：Cancer

authors： Lehrer S,Levine E,Savoretti P,Cropley J,Botstein C,Song HK,Mandell L,Shank B

更新日期：1992-02-15 00:00:00

abstract：:Thirteen patients with a variety of advanced gynecologic malignancies were administered BCG via the dorsal lymphatics of the lower extremity in addition to standard accepted forms of therapy. Prolonged febrile courses, lymphangitis and suppurative adenitis were observed along the lymphatic pathway of the injected lowe...

journal_title：Cancer

authors： Mangan C,Jeglum KA,Sedlacek TV,Giuntoli RL,Wheeler JE,Rubin E,Mikuta JJ

更新日期：1977-12-01 00:00:00

abstract：:The serum lactase dehydrogenase (LDH) of 56 patients with Ewing's sarcoma was examined to determine the use of LDH as a tumor marker. The initial LDH level was used to determine its ability to predict survival. The follow-up LDH level also was examined, as an indicator of recurrent disease. The initial LDH level was f...

journal_title：Cancer

authors： Farley FA,Healey JH,Caparros-Sison B,Godbold J,Lane JM,Glasser DB

更新日期：1987-04-01 00:00:00

abstract：BACKGROUND:During the last two decades, a rising incidence of adenocarcinoma of the esophagus has been observed in the Western world. The prognostic relevance of tumor-biological factors, such as DNA ploidy or c-erbB-2 overexpression, for overall survival following complete resection is still unknown. METHODS:In a ret...

journal_title：Cancer

authors： Nakamura T,Nekarda H,Hoelscher AH,Bollschweiler E,Harbeck N,Becker K,Siewert JR,Harbec N corrected to Harbeck N

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND:Prostate carcinoma is often associated with perineural (PN) invasion. The common occurrence of this phenomenon has led to speculation regarding the mechanisms of this association, yet to date there have been no studies that clearly define biologic differences between PN and nonperineural (NPN) carcinoma cell...

journal_title：Cancer

authors： Yang G,Wheeler TM,Kattan MW,Scardino PT,Thompson TC

更新日期：1996-09-15 00:00:00

abstract：:A Phase I/II accelerated fractionation study for high-grade cerebral astrocytomas began in October 1987. Forty-two patients, 25 men and 17 women, were entered in the study. Median age was 58.5 years of age (range, 32 to 78 years). Performance status was 0, 1, 2, and 3 on Eastern Cooperative Oncology Group (ECOG) scale...

journal_title：Cancer

authors： Shenouda G,Souhami L,Freeman CR,Hazel J,Lehnert S,Joseph L

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND:A study was undertaken to identify new immunogenic human leukocyte antigen (HLA)-A 2402-restricted epitopes from human papillomavirus (HPV) type 16 E7 protein for immunotherapy against cervical cancer. METHODS:Synthetic overlapping peptides were screened by measuring the frequency of CD8(+) cytotoxic T lymp...

journal_title：Cancer

authors： Jang S,Kim YT,Chung HW,Lee KR,Lim JB,Lee K

更新日期：2012-04-15 00:00:00

abstract：:Single meningiomas are histologically classified as benign tumors, but clearly malignant types have been encountered. The standard mode of management is total macroscopic removal with excision of the dural attachment and abnormal bone, if there is any. Despite this aggressive surgery, recurrence rates of approximately...

journal_title：Cancer

authors： Boylan SE,McCunniff AJ

更新日期：1988-04-01 00:00:00

abstract：:A human liposarcoma cell line COLO 222, derived from a primary tumor in a 62-year-old male, elaborates hyaluronic acid. COLO 222 is characterized on the basis of histochemical, ultramorphological, and cytogenetic properties, along with isozyme phenotype and cell products. A chromosome mode of 53 predominates and uniqu...

journal_title：Cancer

authors： Morgan RT,Quinn LA,Moore GE,Semple TU,Woods LK

更新日期：1980-03-15 00:00:00

abstract：BACKGROUND:hMLH1, the human MutL homologue, has been linked to microsatellite instability (MSI) in gastrointestinal tumors. However, to the authors' knowledge, the role of hMLH1, the other mismatch repair genes (MMR), and MSI in ovarian carcinoma has not been well defined. The purpose of the current study was to determ...

journal_title：Cancer

authors： Geisler JP,Goodheart MJ,Sood AK,Holmes RJ,Hatterman-Zogg MA,Buller RE

更新日期：2003-11-15 00:00:00

abstract：BACKGROUND:Vitiligo is a dermatologic disease characterized by local, dispersed, or diffuse white patches on the skin. The disease is defined as an autoimmune disorder because autoantibodies against membranal components of melanocytes are found in the patients' sera. The current study examined whether the autoantibodie...

journal_title：Cancer

authors： Fishman P,Azizi E,Shoenfeld Y,Sredni B,Yecheskel G,Ferrone S,Zigelman R,Chaitchik S,Floro S,Djaldetti M

更新日期：1993-10-15 00:00:00

abstract：:In this study of 454 colorectal carcinoma colectomy specimens, (289 were associated with and 165 were unassociated with schistosomiasis. Schistosome infestation was found to play an etiologic role in bowel malignancy in patients having diffuse involvement of the large intestine and a history of ten years or more of co...

journal_title：Cancer

authors： Ming-Chai C,Chi-Yuan C,Pei-Yu C,Jen-Chun H

更新日期：1980-10-01 00:00:00

abstract：BACKGROUND:Indium-111 labeled antiferritin targets 95% of all Hodgkin's disease lesions with a diameter of 1 cm or more. Subsequent treatment with yttrium-90 labeled antiferritin secures a high response rate in patients with recurrent Hodgkin's disease. METHODS:A total of 87 patients were entered on one of three diffe...

journal_title：Cancer

authors： Vriesendorp HM,Quadri SM,Andersson BS,Wyllie CT,Dicke KA

更新日期：1997-12-15 00:00:00

abstract：:Over a 7 year period, 85 cancer patients were managed by the nutrition service of St. Joseph's Hospital, Toronto. All these patients were nutritionally depleted, had obstruction to the gastrointestinal tract, or had postoperative complications such as enterocutaneous fistulas, evisceration or intraabdominal sepsis, wh...

journal_title：Cancer

authors： Deitel M,Vasic V,Alexander MA

更新日期：1978-06-01 00:00:00

abstract：:The establishment of a maturation-induction model using human colon cancer cells as targets is reported. Two colon carcinoma cell lines were established from human tumors; one line was heterogeneous and was cloned into two distant subpopulations. Cells from these lines and clones and cells from an established human co...

journal_title：Cancer

authors： Dexter DL,Hager JC

更新日期：1980-03-15 00:00:00

abstract：BACKGROUND:The authors previously demonstrated that never-smokers with stage IIIB/IV nonsmall cell lung cancer (NSCLC) lived 50% longer than former/current smokers. This observation persisted after adjusting for age, performance status, and sex. In this study, the authors hypothesized that smoking-dependent differences...

journal_title：Cancer

authors： Paik PK,Johnson ML,D'Angelo SP,Sima CS,Ang D,Dogan S,Miller VA,Ladanyi M,Kris MG,Riely GJ

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Aberrant methylation is a known cause of cancer initiation and/or progression. There are scant data on the genome-wide methylation pattern of nonfunctioning pancreatic neuroendocrine tumors (NFPanNETs) and sporadic and hereditary NFPanNETs. METHODS:Thirty-three tissue samples were analyzed: they included sa...

journal_title：Cancer

authors： Tirosh A,Mukherjee S,Lack J,Gara SK,Wang S,Quezado MM,Keutgen XM,Wu X,Cam M,Kumar S,Patel D,Nilubol N,Tyagi MV,Kebebew E

更新日期：2019-04-15 00:00:00