Orbital lymphoid neoplasms: a clinicopathologic study of 60 patients.

abstract：:From a total of 874 patients with small cell lung cancer (SCC), a series of 104 patients were reviewed to determine if bone marrow relapses are detectable by routine clinical investigations. Autopsy, including microscopical bone marrow examination, was performed in all the 104 patients and bone metastases were disclos...

journal_title：Cancer

authors： Kristjansen PE,Osterlind K,Hansen M

更新日期：1986-12-01 00:00:00

abstract：BACKGROUND:The combination of a platinating agent and etoposide has induced responses in various pediatric tumors. The study estimated the maximum tolerated dose (MTD) of an oxaliplatin and etoposide regimen in children with recurrent solid tumors. METHODS:Oxaliplatin was administered on Day 1 and etoposide on Days 1 ...

journal_title：Cancer

authors： McGregor LM,Spunt SL,Santana VM,Stewart CF,Ward DA,Watkins A,Laningham FH,Ivy P,Furman WL,Fouladi M

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:The carboplatin-based chemotherapeutic regimen M-CAVI (methotrexate, carboplatin, and vinblastine) is active against bladder carcinoma and can be administered to patients who are ineligible to receive cisplatin or doxorubicin. The authors designed a randomized study to evaluate whether M-CAVI offers a therap...

journal_title：Cancer

authors： Bellmunt J,Ribas A,Eres N,Albanell J,Almanza C,Bermejo B,Solé LA,Baselga J

更新日期：1997-11-15 00:00:00

abstract：BACKGROUND:To eliminate cranial irradiation (CrRT)-related sequelae and to minimize the adverse impact of traumatic lumbar puncture (TLP) with blasts, the Taiwan Pediatric Oncology Group (TPOG) introduced a modified central nervous system (CNS)-directed regimen characterized by delayed triple intrathecal therapy (TIT) ...

journal_title：Cancer

authors： Yeh TC,Liang DC,Hou JY,Jaing TH,Lin DT,Yang CP,Peng CT,Hung IJ,Lin KH,Hsiao CC,Jou ST,Chiou SS,Chen JS,Wang SC,Chang TK,Wu KH,Sheen JM,Yen HJ,Chen SH,Lu MY,Li MJ,Chang TT,Huang TH,Chang YH,Chen SH,Yang Y

更新日期：2018-12-01 00:00:00

abstract：:Survival of patients with chronic myeloid leukemia seen in the University of Colorado Leukemia Clinic were reviewed with respect to therapy. A total of 55 patients seen consecutively through mid 1980 were included in this study. Of these patients 30 were treated with busulfan, 14 were treated with hydroxyurea and 11 r...

journal_title：Cancer

authors： Bolin RW,Robinson WA,Sutherland J,Hamman RF

更新日期：1982-11-01 00:00:00

abstract：:The frequency and significance of hyperprolactinemia was studied in 21 consecutive, untreated male patients with bronchogenic carcinoma. Seven patients (33%) were found to have elevated serum prolactin (hPRL) levels. No correlation was demonstrated between increased hPRL levels, tissue histology, or tumor burden. L-do...

journal_title：Cancer

authors： Davis S,Proper S,May PB,Ertel NH

更新日期：1979-08-01 00:00:00

abstract：BACKGROUND:Neovascularization reportedly is correlated with metastasis, recurrence, and prognosis in some types of tumors. Microvessel quantification in so-called "hot spots" has been studied extensively as the only factor reflecting angiogenesis in various malignant tumors. The objective of this report was to evaluate...

journal_title：Cancer

authors： Pavlopoulos PM,Konstantinidou AE,Agapitos E,Kavantzas N,Nikolopoulou P,Davaris P

更新日期：1998-11-15 00:00:00

abstract：:Poor drug compliance may cause a decreased survival of children with malignancies. Children who fail to take their medications are not receiving optimum amounts of chemotherapy and suboptimal therapy causes a shortened survival in children with cancer. This is a study of prednisone compliance in 52 children with cance...

journal_title：Cancer

authors： Smith SD,Rosen D,Trueworthy RC,Lowman JT

更新日期：1979-01-01 00:00:00

abstract：:The techniques of self breast examination and the clinical examination of the breasts are described briefly. The potential value and the limitations of these tests in screening for breast cancer are reviewed. In a Cancer Society Monograph in 1958, Haagensen said, "It is probable that, from the point of view of the gre...

journal_title：Cancer

authors： Venet L

更新日期：1980-08-15 00:00:00

abstract：:Between September 1976 and May 1980, 135 patients with operable breast cancer and positive axillary nodes received l-phenylalanine mustard, adjunct to surgery, 0.15 mg/kg for five days, six weekly, and were randomised prospectively to levamisole 150 mg for three days, two weekly, or a placebo. Treatment was continued ...

journal_title：Cancer

authors： Kay RG,Mason BH,Stephens EJ,Arthur JF,Hitchcock GC,Trindall PL,Rodgers R,Mullins P

更新日期：1983-06-01 00:00:00

abstract：BACKGROUND:The diagnosis of melanomas at an early stage is associated with improved survival, so the recognition of changes in pigmented skin lesions over time is important. We have developed a computer imaging system with the aim of assisting clinicians in differentiating early melanomas from benign pigmented skin les...

journal_title：Cancer

authors： Aitken JF,Pfitzner J,Battistutta D,O'Rourke PK,Green AC,Martin NG

更新日期：1996-07-15 00:00:00

abstract：BACKGROUND:Diabetes is positively associated with various cancers, but its relationship with tumors of the esophagus/esophagogastric junction remains unclear. METHODS:Data were harmonized across 13 studies in the International Barrett's and Esophageal Adenocarcinoma Consortium, comprising 2309 esophageal adenocarcinom...

journal_title：Cancer

authors： Petrick JL,Li N,Anderson LA,Bernstein L,Corley DA,El Serag HB,Hardikar S,Liao LM,Liu G,Murray LJ,Rubenstein JH,Schneider JL,Shaheen NJ,Thrift AP,van den Brandt PA,Vaughan TL,Whiteman DC,Wu AH,Zhao WK,Gammon MD,Coo

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Cisplatin, 5-flourouracil (5-FU), and leucovorin (PFL) chemotherapy has been reported to be effective in the treatment of cancers but severe mucositis or neutropenia are dose limiting toxicities. This Phase II study evaluated the anticancer effect and the toxicities of a new weekly 24-hour infusional PFL che...

journal_title：Cancer

authors： Chi KH,Chan WK,Shu CH,Law CK,Chen SY,Yen SH,Chen KY

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND:Circulating immune complexes (CIC) have been implicated as a cause of malignancy-associated immunosuppression and disease progression. Previous attempts to remove CIC by pheresis or immunoadsorption over a Staphylococcus aureus protein A column have resulted in a few clinical responses, however the relations...

journal_title：Cancer

authors： Fennelly DW,Norton L,Sznol M,Hakes TB

更新日期：1995-04-15 00:00:00

abstract：BACKGROUND:Stomatitis has been found to be a major dose-limiting toxicity from bolus 5-fluorouracil-based (5-FU) chemotherapy regimens, despite the use of oral cryotherapy. Pursuant to preliminary data which suggested that a chamomile mouthwash might ameliorate this toxicity, a prospective trial was developed to test c...

journal_title：Cancer

authors： Fidler P,Loprinzi CL,O'Fallon JR,Leitch JM,Lee JK,Hayes DL,Novotny P,Clemens-Schutjer D,Bartel J,Michalak JC

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND:Although there have been several reports of cytologic features for salivary duct carcinoma (SDC), it still can be difficult to diagnose patients with these tumor accurately at the time of fine-needle aspiration (FNA). Review of the literature indicates that, immunohistochemically, SDC expresses androgen rece...

journal_title：Cancer

authors： Moriki T,Ueta S,Takahashi T,Mitani M,Ichien M

更新日期：2001-10-25 00:00:00

abstract：:To additionally understand the molecular mechanisms and biologic indicators of colonic tumorigenesis through the adenoma-carcinoma sequence, protein kinase C (PKC) activity was examined in the cytosol and particulate fraction of specimen homogenates from 18 human colonic carcinomas and seven coexisting colonic adenoma...

journal_title：Cancer

authors： Kusunoki M,Sakanoue Y,Hatada T,Yanagi H,Yamamura T,Utsunomiya J

更新日期：1992-01-01 00:00:00

abstract：:Actual HL-A typing has been performed on 115 members of cancer family N, a large kindred (over 1000 members ascertained) showing the findings consistent with the cancer family syndrome. In the cancer-prone line (branches C and D) of the family, 20 of 21 members with cancer had one HL-A haplotype, HL-A2-HL-A12 (relativ...

journal_title：Cancer

authors： Lynch HT,Thomas RJ,Terasaki PI,Ting A,Guirgis HA,Kaplan AR,Magee H,Lynch J,Kraft C,Chaperon E

更新日期：1975-10-01 00:00:00

abstract：BACKGROUND:Glioblastoma, which is the most malignant brain tumor, remains incurable and almost always causes death. As a new treatment strategy, the combination of all-trans retinoic acid (ATRA) and paclitaxel was explored for controlling the growth of glioblastoma U87MG xenografts. METHODS:Human glioblastoma U87MG xe...

journal_title：Cancer

authors： Karmakar S,Banik NL,Ray SK

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Previous studies have shown that low levels of p27(Kip1), an inhibitor of G1 cyclin-dependent kinases, are associated with high aggressiveness and poor prognosis in a variety of cancers. Decreased levels of p27 are caused, at least in part, by acceleration of the rate of its ubiquitin-mediated degradation. I...

journal_title：Cancer

authors： Hershko D,Bornstein G,Ben-Izhak O,Carrano A,Pagano M,Krausz MM,Hershko A

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Microsatellite instability occurs frequently in hereditary nonpolyposis colorectal carcinoma, in sporadic gastrointestinal carcinoma, and in other tumors. In these tumors, slippage-related frameshift mutations have been detected at coding mononucleotide repeats in genes such as those for transforming growth ...

journal_title：Cancer

authors： Saeki A,Tamura S,Ito N,Kiso S,Matsuda Y,Yabuuchi I,Kawata S,Matsuzawa Y

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:The prognosis of patients with clinically staged hilar nodal involvement (Stage N1) or clinical Stage II non-small cell lung cancer (NSCLC, Stage T1-2N1M0) treated with radiation therapy (RT) alone is not well established. METHODS:Records of 758 patients with clinical Stage I-III NSCLC treated with RT were ...

journal_title：Cancer

authors： Rosenthal SA,Curran WJ Jr,Herbert SH,Hughes EN,Sandler HM,Stafford PM,McKenna WG

更新日期：1992-11-15 00:00:00

abstract：BACKGROUND:It has been established that comparative genomic hybridization (CGH) on Papanicolaou-stained cervical smears can be used to identify chromosomal imbalances. METHODS:In this study, the authors identified normal and dysplastic squamous epithelial cells cytologically, eliminated surrounding bacteria or leukocy...

journal_title：Cancer

authors： Aubele M,Zitzelsberger H,Schenck U,Walch A,Höfler H,Werner M

更新日期：1998-12-25 00:00:00

abstract：BACKGROUND:Specific kinase activity of the proto-oncogene product pp60(c-src) is reported to be elevated in patients with carcinoma of the colon, and a novel cytoplasmic protein-tyrosine kinase, C-terminal Src kinase (Csk), has been found to inactivate the members of the Src family protein-tyrosine kinase. In this stud...

journal_title：Cancer

authors： Cam WR,Masaki T,Shiratori Y,Kato N,Ikenoue T,Okamoto M,Igarashi K,Sano T,Omata M

更新日期：2001-07-01 00:00:00

abstract：:The cellular DNA content was determined in a consecutive series of 26 classical and two paraosteal osteosarcomas by means of single cell cytophotometry. All classical osteosarcomas regardless of histologic type (osteo-, chondro-, fibroblastic) or grade were found to be hyperploid (abnormally increased DNA content) whi...

journal_title：Cancer

authors： Kreicbergs A,Broström LA,Cewrien G,Einhorn S

更新日期：1982-12-01 00:00:00

abstract：:Patients who are diagnosed with osteosarcoma (OS) today receive the same therapy that patients have received over the last 4 decades. Extensive efforts to identify more effective or less toxic regimens have proved disappointing. As we enter a postgenomic era in which we now recognize OS not as a cancer of mutations bu...

journal_title：Cancer

authors： Roberts RD,Lizardo MM,Reed DR,Hingorani P,Glover J,Allen-Rhoades W,Fan T,Khanna C,Sweet-Cordero EA,Cash T,Bishop MW,Hegde M,Sertil AR,Koelsche C,Mirabello L,Malkin D,Sorensen PH,Meltzer PS,Janeway KA,Gorlick R,Cro

更新日期：2019-10-15 00:00:00

abstract：BACKGROUND:Prostate specific antigen (PSA) is useful as a tumor marker for monitoring patients with prostate cancer after definitive therapy. Limitations have been noted when PSA was used for the early detection of prostate cancer. The use of prostate specific antigen density [PSAD = PSA (ng/ml)/prostate volume (cc)] h...

journal_title：Cancer

authors： Bretton PR,Evans WP,Borden JD,Castellanos RD

更新日期：1994-12-01 00:00:00

abstract：:Twenty-three leukemic children were studied prospectively to detect chronic effects of therapy. All patients received CNS prophylaxis, including 2400 R cranial irradiation, and intermittent maintenance therapy with intravenous methotrexate, cyclophosphamide and cytosine arabinoside. Neurologic symptoms were observed i...

journal_title：Cancer

authors： McIntosh S,Klatskin EH,O'Brien RT,Aspnes GT,Kammerer BL,Snead C,Kalavsky SM,Pearson HA

更新日期：1976-02-01 00:00:00

abstract：BACKGROUND:Effective multidisciplinary rehabilitation programs supporting the return to work have become increasingly relevant for cancer survivors. In Germany, inpatient work-related medical rehabilitation programs consider treatment modules of work-related diagnostics, work-related functional capacity training, psych...

journal_title：Cancer

authors： Fauser D,Wienert J,Beinert T,Schmielau J,Biester I,Krüger HU,Presl A,Bethge M

更新日期：2019-08-01 00:00:00

abstract：:The distribution of synchronous neoplasms was retrospectively analyzed in 220 patients undergoing initial colonoscopic evaluation for colorectal neoplasms. In 159 of the 220 patients, an index neoplasm was present in the rectosigmoid region. Of these 159 patients, 32 had an index rectosigmoid adenoma less than 5 mm in...

journal_title：Cancer

authors： Tripp MR,Morgan TR,Sampliner RE,Kogan FJ,Protell RL,Earnest DL

更新日期：1987-10-01 00:00:00