Medical oncology and geriatric medicine: is it time for fellowship integration?

abstract：BACKGROUND:Although acquired somatic mutations presumably are crucial in carcinogenesis, nothing is known about the chromosome aberrations of bilateral breast carcinomas. METHODS:Eighteen specimens from 16 bilateral carcinomas were analyzed cytogenetically. The banding analysis was supplemented with fluorescence in si...

journal_title：Cancer

authors： Pandis N,Teixeira MR,Gerdes AM,Limon J,Bardi G,Andersen JA,Idvall I,Mandahl N,Mitelman F,Heim S

更新日期：1995-07-15 00:00:00

abstract：:Activity of Poly (C) avid ribonuclease was estimated in sera of 129 patients with different malignancies. All patients had histologically verified carcinomas, normal renal function, and no signs of acute catabolic condition. Activity values were compared with those of normal subjects (U-test, Mann and Whitney) separat...

journal_title：Cancer

authors： Francesconi M,Meryn S,Rogan AM,Szalay S,Graninger W,Schmidbauer CP

更新日期：1984-05-01 00:00:00

abstract：:The clinical findings in 262 patients with melanoma were correlated with an assessment of their cellular-mediated immunity by delayed-type hypersensitivity (DTH) skin tests, by lymphocyte blastogenesis, and by leukocyte enumerations. Patients with systemic metastases (stage IV) and those with evidence of tumor burden ...

journal_title：Cancer

authors： Pritchard DJ,Ritts RE Jr,Taylor WF,Miller GC

更新日期：1978-06-01 00:00:00

abstract：:This survey of the incidence of melanoma in New South Wales, Australia, from 1970 to 1976 revealed a doubling of incidence in the seven year period. The most marked rise occurred in 1972. A marked preponderance of leg melanoma in women and trunk melanoma in men was noted. The incidence of melanoma in men continues to ...

journal_title：Cancer

authors： McCarthy WH,Black AL,Milton GW

更新日期：1980-07-15 00:00:00

abstract：:Giant sections from cystectomy specimens in 45 cases of bladder cancer were examined microscopically after en bloc fixation and processing. There were 35 transitional cell, seven squamous cell, and three mixed transitional cell and squamous carcinomas. Broad front invasion was associated with papillary and superficial...

journal_title：Cancer

authors： Soto EA,Friedell GH,Tiltman AJ

更新日期：1977-02-01 00:00:00

abstract：BACKGROUND:The objective of this study was to assess whether coregistered whole brain (WB) magnetic resonance imaging-positron emission tomography (MRI-PET) would increase the number of correctly upstaged patients compared with WB PET-computed tomography (PET-CT) plus dedicated brain MRI in patients with nonsmall cell ...

journal_title：Cancer

authors： Yi CA,Lee KS,Lee HY,Kim S,Kwon OJ,Kim H,Choi JY,Kim BT,Hwang HS,Shim YM

更新日期：2013-05-15 00:00:00

abstract：BACKGROUND:Neovascularization reportedly is correlated with metastasis, recurrence, and prognosis in some types of tumors. Microvessel quantification in so-called "hot spots" has been studied extensively as the only factor reflecting angiogenesis in various malignant tumors. The objective of this report was to evaluate...

journal_title：Cancer

authors： Pavlopoulos PM,Konstantinidou AE,Agapitos E,Kavantzas N,Nikolopoulou P,Davaris P

更新日期：1998-11-15 00:00:00

abstract：BACKGROUND:The hepatitis activity index (HAI) score describes the histologic status of accompanying chronic hepatitis and was established by pathologists. The aim of this study was twofold: 1) to investigate the correlation between intrahepatic metastatic recurrence (IM) and the HAI score of the noncancerous region of ...

journal_title：Cancer

authors： Ueno S,Tanabe G,Yoshida A,Yoshidome S,Takao S,Aikou T

更新日期：1999-07-15 00:00:00

abstract：BACKGROUND:To the authors' knowledge, comprehensive human pathologic investigations that explore fundamental radiosurgical effects on metastatic brain tumors are sparse in the literature. The objective of this study was to analyze histopathologic findings in a set of clinically recurrent cerebral metastases after patie...

journal_title：Cancer

authors： Szeifert GT,Atteberry DS,Kondziolka D,Levivier M,Lunsford LD

更新日期：2006-06-15 00:00:00

abstract：:Clinically benign whole, untrimmed prostates and pelvic lymph nodes were obtained from 105 patients at autopsy. All 105 patients had premortem serum from which prostate-specific antigen (PSA) levels were obtained. Sixty-eight did not have carcinoma of the prostate (CAP), 28 had CAP less than 1 ml and 9 had CAP larger ...

journal_title：Cancer

authors： Brawn PN,Speights VO,Kuhl D,Riggs M,Spiekerman AM,McCord RG,Coffield KS,Stewart DT,Lind ML

更新日期：1991-10-01 00:00:00

abstract：BACKGROUND:Screening over many years is required to optimize reductions in colorectal cancer (CRC) mortality. However, no prior trials have compared strategies for obtaining long-term adherence. METHODS:Systems of Support to Increase Colorectal Cancer Screening and Follow-Up was implemented in an integrated health car...

journal_title：Cancer

authors： Green BB,Anderson ML,Cook AJ,Chubak J,Fuller S,Meenan RT,Vernon SW

更新日期：2017-11-15 00:00:00

abstract：:Seventeen patients with carcinoma confined to the pancreas and the peripancreatic area received preoperative radiation therapy in an attempt to increase the resectability rate and to reduce the incidence of recurrence. The tumors were considered either unresectable or of borderline resectability. The radiation dose ra...

journal_title：Cancer

authors： Pilepich MV,Miller HH

更新日期：1980-11-01 00:00:00

abstract：BACKGROUND:This randomized pilot trial investigated whether primary chemotherapy was feasible in terms of efficacy, survival, toxicity profile, and quality of life compared with whole-brain radiotherapy (WBRT) given first in chemotherapy-naive patients nonsmall cell lung cancer (NSCLC) with synchronous brain metastasis...

journal_title：Cancer

authors： Lee DH,Han JY,Kim HT,Yoon SJ,Pyo HR,Cho KH,Shin SH,Yoo H,Lee SH,Lee JS

更新日期：2008-07-01 00:00:00

abstract：:Between August 1978 and November 1981, 33 boys with acute lymphocytic leukemia (ALL) (26 non-T, 7 T-cell) younger than 16 years underwent bilateral wedge testicular biopsies at the time of initial diagnosis. Seven (4 non-T, 3 T-cell) demonstrated focal leukemic infiltrates. Rebiopsy after successful induction therapy ...

journal_title：Cancer

authors： Kim TH,Hargreaves HK,Chan WC,Brynes RK,Alvarado C,Woodard J,Ragab AH

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND:Nude mice with xenografted human tumors is the most exploited animal model used to elucidate the efficacy of experimental radioimmunolocalization and radioimmunotherapy. These animals accept transplants and are generally considered immunologically inert with regard to cell-mediated and humoral immune respons...

journal_title：Cancer

authors： Stigbrand T,Ullén A,Sandström P,Rathsman S,Rossi Norrlund R,Arlestig L,Riklund Ahlström K,Hietala SO

更新日期：1997-12-15 00:00:00

abstract：:Two consecutive trials for the treatment of childhood non-Hodgkin's lymphoma were evaluated, carried out by the same cooperative groups. Group A: From June, 1973 to December, 1975, 50 evaluable patients under 16 years of age participated in a study that included vincristine and prednisone plus surgery and/or radiother...

journal_title：Cancer

authors： Sackmann-Muriel F,Diez B,Schvartzman E,Braier JL,Schwartz L,Gallo G,Pavlovsky S

更新日期：1984-12-15 00:00:00

abstract：:Identification of BCR-ABL as the defining leukemogenic event in chronic myelogenous leukemia (CML) revolutionized the treatment of the disease. Imatinib, a potent BCR-ABL inhibitor, is the standard of care for the first-line treatment of patients with chronic-phase CML because of its high long-term response rates and ...

journal_title：Cancer

authors： Kantarjian HM,Cortes J,La Rosée P,Hochhaus A

更新日期：2010-03-15 00:00:00

abstract：BACKGROUND:The use of adjuvant tamoxifen to treat postmenopausal breast carcinoma patients as an adjunct to primary surgery is well established. The current study reports the long term results for a low risk stratum in a randomized trial of adjuvant tamoxifen. The main focus of this analysis was to determine whether ta...

journal_title：Cancer

authors： Dalberg K,Johansson H,Johansson U,Rutqvist LE

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND:Sentinel lymph node (SLN) sampling is used to predict axillary lymph node (AxLN) metastasis in patients with breast carcinoma; AxLN sampling can be avoided in SLN-negative patients. Multistep sectioning and immunohistochemistry are reported to increase the sensitivity of micrometastasis detection. The author...

journal_title：Cancer

authors： Munakata S,Aihara T,Morino H,Takatsuka Y

更新日期：2003-10-15 00:00:00

abstract：BACKGROUND:The purpose of this study was to assess prostate carcinoma detection and discrimination of benign from malignant prostate tissue with contrast-enhanced ultrasonography. METHODS:In all, 301 subjects referred for prostate biopsy were evaluated with contrast-enhanced sonography using continuous harmonic imagin...

journal_title：Cancer

authors： Halpern EJ,Ramey JR,Strup SE,Frauscher F,McCue P,Gomella LG

更新日期：2005-12-01 00:00:00

abstract：:Fifteen oncocytic (oxyphilic granular cell) neoplasms of the salivary glands collected from three large university medical centers are presented. The histologic and ultrastructural criteria that characterize oncocytes are presented and electron micrographs of two of our cases are discussed. Included in the series are ...

journal_title：Cancer

authors： Gray SR,Cornog JL Jr,Seo IS

更新日期：1976-09-01 00:00:00

abstract：BACKGROUND:The clinical dose of 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-1-(2-chloroethyl)-1-nitro- sourea hydrochloride (ACNU) is limited by the bone marrow suppression it produces. The authors investigated whether bone marrow transplantation (BMT) associated with a high dose of ACNU could alleviate marrow toxicity ...

journal_title：Cancer

authors： Soma M,Shoin K,Yamashita J

更新日期：1993-01-15 00:00:00

abstract：:In an article published in this issue of Cancer, D'Arcy et al link the incidence of cancer among recipients of solid organ transplantation (SOT) in the Scientific Registry of Transplant Recipients with data from regional and statewide cancer registries to examine cancer-specific mortality for common malignancies in SO...

journal_title：Cancer

authors： Koff JL,Waller EK

更新日期：2019-03-15 00:00:00

abstract：:Low-dose continuous infusion 5-fluorouracil (LDCI-FU) was administered to 28 women with advanced breast carcinoma. Daily doses ranged from 175 to 250 mg/m2. The LDCI-FU was delivered continuously until the appearance of toxicity and was reinstituted at a 20% dose reduction after toxicity completely resolved. Patients ...

journal_title：Cancer

authors： Huan S,Pazdur R,Singhakowinta A,Samal B,Vaitkevicius VK

更新日期：1989-02-01 00:00:00

abstract：:Three cases of peritoneal papillary serous carcinoma with a complete response to chemotherapy and long-term disease free survival are reported. All three patients presented with multifocal or diffuse peritoneal involvement. Microscopic ovarian serosal surface involvement was demonstrated in two cases. The ovaries were...

journal_title：Cancer

authors： Chen KT,Flam MS

更新日期：1986-09-15 00:00:00

abstract：BACKGROUND:Tobacco smoking, alcohol abuse, and high-risk human papillomavirus (HPV) are risk factors in the etiology of oropharyngeal squamous cell carcinomas (SCCs). The TP53 polymorphism, in which an arginine (R) is changed to proline (P) at codon 72, is functionally significant and could therefore be a predisposing ...

journal_title：Cancer

authors： Perrone F,Mariani L,Pastore E,Orsenigo M,Suardi S,Marcomini B,DaRiva L,Licitra L,Carbone A,Pierotti MA,Pilotti S

更新日期：2007-06-15 00:00:00

abstract：BACKGROUND:In the United States, incidence rates for malignant tumors of the uterine corpus are lower among blacks than among whites, whereas mortality rates are higher among blacks. Reasons for the higher level of mortality among blacks have been debated. METHODS:Using data from the Surveillance, Epidemiology, and En...

journal_title：Cancer

authors： Sherman ME,Devesa SS

更新日期：2003-07-01 00:00:00

abstract：:A pilot study was done to determine the feasibility of adjuvant photodynamic therapy (PDT) in recurrent retroperitoneal sarcomas. Ten patients, who had recurrences after conventional methods of treatment, had repeated resections of the tumor and intraoperative photodynamic treatment to the tumor bed. The methods and e...

journal_title：Cancer

authors： Nambisan RN,Karakousis CP,Holyoke ED,Dougherty TJ

更新日期：1988-03-15 00:00:00

abstract：:From January, 1973, to June, 1976, 226 patients with palpable ovarian masses were evaluated preoperatively by lymphography. Histology showed 166 cases of malignant epithelial tumors, 26 benign tumors, and 34 malignant special tumors (not included in this report). Furthermore, the group of patients included 99 recurren...

journal_title：Cancer

authors： Musumeci R,Banfi A,Bolis G,Candiani GB,De Palo G,Di Re F,Lucina L,Lattuada A,Mangioni C,Mattioli G,Natale N

更新日期：1977-10-01 00:00:00

abstract：:The serum lactase dehydrogenase (LDH) of 56 patients with Ewing's sarcoma was examined to determine the use of LDH as a tumor marker. The initial LDH level was used to determine its ability to predict survival. The follow-up LDH level also was examined, as an indicator of recurrent disease. The initial LDH level was f...

journal_title：Cancer

authors： Farley FA,Healey JH,Caparros-Sison B,Godbold J,Lane JM,Glasser DB

更新日期：1987-04-01 00:00:00