Cerebral metastases pathology after radiosurgery: a multicenter study.

abstract：:Twelve cases of ovarian adenocarcinoma were studied for alterations in proto-oncogenes, and a unique pattern of altered ras proto-oncogenes was observed. Amplification of ras-Ki was found in three of seven ovarian tumors and amplification of ras-Ha in one of 12. In contrast, ras-Ha amplification was not found in any o...

journal_title：Cancer

authors： Zhou DJ,Gonzalez-Cadavid N,Ahuja H,Battifora H,Moore GE,Cline MJ

更新日期：1988-10-15 00:00:00

abstract：BACKGROUND:Informed consent has been proposed as the optimal method for ensuring the ethical entry of patients into clinical trials. However, it is known that problems with informed consent exist from the perspective of both patients and physicians. This has led to the suggestion that a third party, such as a research ...

journal_title：Cancer

authors： Loh WY,Butow PN,Brown RF,Boyle F

更新日期：2002-12-01 00:00:00

abstract：:Pain management often is difficult in patients with bone metastases. Metastatic disease represents >40% of oncologic practice, and >70% of patients with metastatic disease have uncontrolled cancer-related pain. Significant morbidity caused by pathologic fracture and spinal cord compression can result from untreated bo...

journal_title：Cancer

authors： Janjan NA

更新日期：1997-10-15 00:00:00

abstract：:The role of hyperthermic isolation perfusion in the treatment of advanced melanoma of the limbs is clearly important. However, attention has in the past been focussed mainly on surgical aspects of the procedure. Whereas, equivalent interest in chemotherapy considerations has been lacking. A group of 15 patients have b...

journal_title：Cancer

authors： Klein ES,Ben-Ari GY

更新日期：1987-03-15 00:00:00

abstract：BACKGROUND:Greater than one-half of children who are treated for acute lymphoblastic leukemia (ALL) develop ≥1 treatment-related medical conditions in their lifetime, many of which are known risk factors for diabetes mellitus. In the current study, the authors evaluated the prevalence and risk factors of diabetes melli...

journal_title：Cancer

authors： Williams HE,Howell CR,Chemaitilly W,Wilson CL,Karol SE,Nolan VG,Smeltzer MP,Green DM,Ehrhardt MJ,Mulrooney DA,Pui CH,Hudson MM,Robison LL,Ness KK

更新日期：2020-02-15 00:00:00

abstract：BACKGROUND:Epidermal growth factor (EGF) and EGF-regulated processes play an important role in steroid signal transduction. Comparative analysis of EGF and steroid receptor expression and the sensitivity of early stages of proliferation induction, such as activation of phospholipid turnover to EGF and steroids, may pro...

journal_title：Cancer

authors： Gershtein ES,Shatskaya VA,Kostyleva OI,Ermilova VD,Kushlinsky NE,Krasil'nikov MA

更新日期：1995-12-15 00:00:00

abstract：:Combined modality therapy consisting of CHOP-Bleo (cyclophosphamide, Adriamycin [doxorubicin], vincristine (Oncovin), prednisone, and bleomycin) and limited-field radiotherapy was given to 47 patients with Stage III and IIIE diffuse large cell lymphomas. Overall 5-year survival and disease-free survival figures are 64...

journal_title：Cancer

authors： Velasquez W,Fuller LM,Oh KK,Hagemeister FB,Sullivan JA,Manning JT,Shullenberger CC

更新日期：1984-04-01 00:00:00

abstract：:Nine patients from 34 to 74 years of age (median, 67 years of age) with uterine papillary serous carcinoma (UPSC) were treated with whole-abdominal radiation therapy (WART) on an adjuvant basis after cytoreductive surgery. All patients were treated with megavoltage photons to an abdominopelvic field to a median dose o...

journal_title：Cancer

authors： Frank AH,Tseng PC,Haffty BG,Papadopoulos DP,Kacinski BM,Dowling SW,Carcangiu ML,Kohorn EI,Chambers JT,Chambers SK

更新日期：1991-10-01 00:00:00

abstract：BACKGROUND:The bone destruction in myeloma patients is largely responsible for the clinical features of the disease. However, only recently has attention focused on identifying and developing drugs targeted specifically at the osteolysis. Receptor activator of NF-kappaB ligand (RANKL), macrophage inflammatory protein (...

journal_title：Cancer

authors： Oyajobi BO,Mundy GR

更新日期：2003-02-01 00:00:00

abstract：:A strong activity of the tartrate-resistant acid phosphatase, isoenzyme 5b, was observed in mouse spleen. The enzyme of the mouse spleen had similar electrophoretic mobility and related antigenicity to that of the reticulum cells of leukemic reticuloendotheliosis. Enzyme histochemical studies showed many non-phagocyti...

journal_title：Cancer

authors： Kuehler D,Lam KW,Yam LT

更新日期：1981-02-15 00:00:00

abstract：INTRODUCTION:The presence of nodal metastases remains the most significant predictive factor for regional recurrence and survival in patients treated for squamous cell carcinoma of the head and neck. Survival rates are further decreased in patients with nodal metastases that have spread beyond the lymph node capsule, o...

journal_title：Cancer

authors： Myers JN,Greenberg JS,Mo V,Roberts D

更新日期：2001-12-15 00:00:00

abstract：:A case of endometrial adenoacanthoma is reported in which two histologically distinct populations of cells were identified in the primary tumor. The two cell types differed in that one had phagocytosed large numbers of polymorphonuclear leucocytes. A subsequent skin metastasis was composed entirely of cells capable of...

journal_title：Cancer

authors： Chandrasoma P

更新日期：1980-05-01 00:00:00

abstract：BACKGROUND:Flow cytometric analysis of trophoblastic tissue has shown that most partial hydatidiform moles (PMs) are triploid, whereas most complete moles (CMs) are diploid or tetraploid. Ploidy analysis can support a diagnosis of CM or PM. However, in some cases, a precise diagnosis cannot be rendered. METHODS:This s...

journal_title：Cancer

authors： Bocklage TJ,Smith HO,Bartow SA

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:Breast carcinoma survivors are the largest segment of the expanding cancer survivor community. As a result, there has been increasing discussion of the safety and efficacy of hormone replacement therapy for women with a past history of breast carcinoma. Little is known about the willingness of older breast c...

journal_title：Cancer

authors： Ganz PA,Greendale GA,Kahn B,O'Leary JF,Desmond KA

更新日期：1999-09-01 00:00:00

abstract：:Lobular carcinoma in situ (LCIS) has uncertain malignant potential; biologic markers that will identify patients at risk for a poor clinical outcome have been sought actively. Amplification of the c-erbB-2 protooncogene has been correlated with poor prognosis in invasive mammary carcinoma, and immunohistochemical eval...

journal_title：Cancer

authors： Porter PL,Garcia R,Moe R,Corwin DJ,Gown AM

更新日期：1991-07-15 00:00:00

abstract：:A pilot study was done to determine the feasibility of adjuvant photodynamic therapy (PDT) in recurrent retroperitoneal sarcomas. Ten patients, who had recurrences after conventional methods of treatment, had repeated resections of the tumor and intraoperative photodynamic treatment to the tumor bed. The methods and e...

journal_title：Cancer

authors： Nambisan RN,Karakousis CP,Holyoke ED,Dougherty TJ

更新日期：1988-03-15 00:00:00

abstract：:Review of the consultation records of the Gastrointestinal Surgical Oncology service at Roswell Park Memorial Institute from 1982 to 1987 revealed 22 patients with a clinical diagnosis of neutropenic enterocolitis. Ninety-one percent of the patients had hematologic malignancies, and 95% were receiving cytotoxic chemot...

journal_title：Cancer

authors： Wade DS,Nava HR,Douglass HO Jr

更新日期：1992-01-01 00:00:00

abstract：:In this review, I describe the polymerase chain reaction (PCR) and its application to cancer diagnostics. I present recent improvements to PCR methodology, and describe some state-of-the-art detection methods and approaches used to diagnose various cancer markers, including ras genes, BCR/abl translocations, and G-pro...

journal_title：Cancer

authors： Lyons J

更新日期：1992-03-15 00:00:00

abstract：:Androgen deprivation therapy (ADT) is now a well-established standard of care in combination with definitive radiotherapy for patients with unfavorable intermediate-risk to high-risk locally advanced prostate cancer. It is also well established that combination modality treatment with ADT and radiotherapy is superior ...

journal_title：Cancer

authors： Roach M 3rd

更新日期：2014-06-01 00:00:00

abstract：:Regressing atypical histiocytosis (RAH) of skin is a cutaneous noduloulcerative proliferation of atypical neoplastic histiocytes with concomitant polymorphous inflammation, frequently pronounced epidermal hyperplasia, and an unexpectedly indolent biologic course. Spontaneous regression and recurrence without systemic ...

journal_title：Cancer

authors： Flynn KJ,Dehner LP,Gajl-Peczalska KJ,Dahl MV,Ramsay N,Wang N

更新日期：1982-03-01 00:00:00

abstract：BACKGROUND:Stepwise progression of peripheral-type lung adenocarcinoma was characterized morphologically and was related to prognosis. Expression of the tumor suppressor gene p16 in pulmonary adenocarcinoma decreased, mainly as a result of aberrant methylation of the CpG islands of the promoter region. METHODS:Aberran...

journal_title：Cancer

authors： Tanaka R,Wang D,Morishita Y,Inadome Y,Minami Y,Iijima T,Fukai S,Goya T,Noguchi M

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:Management of unresectable colorectal liver metastases (CLM) can be by regional (hepatic arterial infusion [HAI]) or systemic chemotherapy, or by symptom control alone. In this study the costs of each type of management were related to clinical outcome in 134 patients with CLM. METHODS:The costs (both in te...

journal_title：Cancer

authors： Durand-Zaleski I,Earlam S,Fordy C,Davies M,Allen-Mersh TG

更新日期：1998-09-01 00:00:00

abstract：:Two patients with superior vena cava syndrome (SVCS) recurring after maximum-tolerance radiation were treated by placing a Gianturco expandable wire stent (GEWS) into the obstructed superior vena cava. The SVCS symptoms rapidly disappeared and good short-term (6 months) palliation was achieved. GEWS placement is a pro...

journal_title：Cancer

authors： Rösch J,Bedell JE,Putnam J,Antonovic R,Uchida B

更新日期：1987-09-15 00:00:00

abstract：BACKGROUND:Scarce data exist concerning the outcome of very elderly patients with head and neck squamous cell carcinoma (HNSCC). METHODS:The clinical files of 316 patients aged > or = 80 years with HNSCC who were included in the authors' hospital database between 1987 and 2006 were reviewed retrospectively. RESULTS:A...

journal_title：Cancer

authors： Italiano A,Ortholan C,Dassonville O,Poissonnet G,Thariat J,Benezery K,Vallicioni J,Peyrade F,Marcy PY,Bensadoun RJ

更新日期：2008-12-01 00:00:00

abstract：:Two children with metastatic extragonadal endodermal sinus tumor who had failed VAC chemotherapy were treated with combination chemotherapy consisting of cis-platinum, vinblastine, doxorubicin HCl (Adriamycin) and bleomycin (cis-VAB). There was a complete response in both patients with one child remaining tumor-free 3...

journal_title：Cancer

authors： Thomas WJ,Kelleher JF,Duval-Arnould B

更新日期：1981-12-01 00:00:00

abstract：BACKGROUND:Two-thirds of cancer cases are associated with two lifestyle practices: 35% with the typical American diet, and 30% with tobacco use. In contrast to the field of tobacco control, research and resources dedicated to the field of nutrition have been limited, in part because dietary change has been considered c...

journal_title：Cancer

authors： Bal DG,Foerster SB

更新日期：1993-08-01 00:00:00

abstract：:In 25 patients under treatment or during follow-up for acute lymphoblastic leukemia magnetic resonance imaging (MRI) of both knees was compared to history and physical examination to detect osteonecrosis. Results of MRI were classified as: O, normal bone marrow (BM); 1, diffuse decrease in signal intensity; 2, circums...

journal_title：Cancer

authors： Pieters R,van Brenk AI,Veerman AJ,van Amerongen AH,van Zanten TE,Golding RP

更新日期：1987-12-15 00:00:00

abstract：BACKGROUND:The Akt/mammalian target of rapamycin (mTOR) pathway mediates cell survival and proliferation and contributes to tumor progression. Soft tissue leiomyosarcoma continues to show poor prognosis, and little is known about its mechanisms of tumor progression. Here the authors investigated the significance of act...

journal_title：Cancer

authors： Setsu N,Yamamoto H,Kohashi K,Endo M,Matsuda S,Yokoyama R,Nishiyama K,Iwamoto Y,Dobashi Y,Oda Y

更新日期：2012-03-15 00:00:00

abstract：BACKGROUND:Efficient quality assurance and improvement measures are essential ingredients in a well organized cytology-based program for cervical carcinoma screening. Various pap smear review procedures, aiming for optimization of accuracy, are described throughout the literature. Evaluation and synthesis of those meth...

journal_title：Cancer

authors： Arbyn M,Schenck U,Ellison E,Hanselaar A

更新日期：2003-02-25 00:00:00

abstract：:Fiberoptic endoscopic examination and biopsy of the nasopharynx was done in 130 patients as a prospective study. They all had elevated titers of antibodies against the viral capsid antigen of Epstein-Barr virus but no symptoms or signs of nasopharyngeal carcinoma. Each underwent a biopsy from six fixed sites in the na...

journal_title：Cancer

authors： Wei WI,Sham JS,Zong YS,Choy D,Ng MH

更新日期：1991-06-15 00:00:00